• Asian Pacific Journal of Cancer Prevention
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• 제15권11호
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• pp.4411-4416
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• 2014

Breast cancer is the most common cancer in females all over the world with approximately one million new cases each year as well as one of second leading causes of death among females. In Pakistan, the most frequently diagnosed cancer among females is also breast cancer, accounting for nearly one in nine female patients. Its incidence in Pakistan is 2.5 times higher than that in neighboring countries like Iran and India. The risk factors associated with breast cancer are age, family history, early menarche, intake of combined estrogen and progestin menopausal hormones, alcohol consumption, physical inactivity, low socioeconomic status and lack of awareness regarding the disease. This mini-review article aims to provide awareness about breast cancer as well as an updated knowledge about the prevalence, risk factors and disease knowledge of breast cancer in Pakistan.

• 한국농림기상학회지
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• 제7권4호
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• pp.240-249
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• 2005

일반적으로 인도양 동쪽 해수면 온도는 따뜻하고, 서쪽 해수면 온도는 차갑다. 이러한 인도양 동/서쪽의 해수면 온도 변화는 인도 해양 다이폴 현상(Indian Ocean Dipole Mode, IODM)이 그 원인이다. 다이폴의 양의 위상은 서쪽 인도양에 양의 SST 아노말 리가 나타나고, 남동 인도양에는 음의 SST 아노말리가 나타나고 음의 위상은 이와 반대의 SST 아노말리가 나타난다. 반면 태평양의 경우, 일반적으로 서쪽 해수면 온도는 따뜻하고, 동쪽 해수면 온도는 차갑다. 중앙/동(서) 태평양 해양의 양(음)의 SST 아노말리가 현상이 나타날 때는 엘니뇨 시기이다. 이와 반대의 SST 아노말리 현상은 라니냐 시기이다 이러한 태평양의 대기-해양간의 상호작용으로 나타나는 현상을 엘니뇨 난방진동(El Nino Southern Oscillation, ENSO)이라 한다. 본 연구에서는 IODM과 ENSO현상에 따른 동아시아 몬순 변동성을 분석하기 위해 관측자료와 NCAR MCA모델 자료를 사용하였다 IODM과 ENSO 현상과 관련된 SST 아노말리 5가지 실험을 수행하였다. IDO모드는 최고의 값이 나타난 이후 약 $3\~4$계절의 시간 지연을 가지고 동아시아의 여름 몬순 활동에 영향을 주는 반면, ENSO는 동아시아 여름 몬순과 같은 계절에 영향을 준다. IODM 음(양의)위상과 태평양에서의 엘니뇨(라니냐) 현상은 한국과 일본지역에서 몬순 활동을 강화(억제)하는 역할을 한다. 반면 중국 지역에서는 IDOM과 몬순 변동성과는 별다른 연관성이 없는 것으로 나타났다. 그러나 엘니뇨(라니냐)일 때, 중국 지역에서 몬순 활동은 억제(강화)되는 경향을 보였다. IODM은 북태평양 아열대 고기압이 강화 할 때 나타나고, ENSO는 북서 태평양 알류산 저기압의 영향으로 나타난다. 따라서 태평양으로부터 동아시아 쪽으로의 수분 공급은 아열대 고기압과 알류산 저기압의 강화/약화에 의해 결정된다.

• 한국지구과학회지
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• 제28권5호
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• pp.585-597
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• 2007

The characteristics of the rainfall events on the Korean peninsula have been investigated by means of regional and global observational data collected from 1954 to 2004 with an emphasis on extreme cases $80\;mm\;day^{-1}$. According to our analysis, long-term annual rainfall anomalies show an increasing trend. This trend is pronounced in the month of August, when both the amount of monthly rainfall and the frequency of extreme events increase significantly. Composite maps on August during the 8 wet years reveal warm SST anomalies over the eastern Philippine Sea which are associated with enhanced convection and vertical motion and intensified positive SLP over central Eurasia during August. The rainfall pattern suggests that the most significant increase in moisture supply over the southern parts of China and Korea in August is associated with positive SLP changes over Eurasia and negative SLP changes over the subtropical western Pacific off the east coast of south China. The frequent generation of typhoons over the warm eastern Philippine Sea and their tracks appear to influence the extreme rainfall events in Korea during the month of August. The typhoons in August mainly passed the western coast of Korea, resulting in the frequent occurrence of extreme rainfall events in this region. Furthermore, anomalous cyclonic circulations over the eastern Philippine Sea also promoted the generation of tropical cyclones. The position of pressure systems - positive SLP over Eurasia and negative SLP over the subtropical Pacific - in turn provided a pathway for typhoons. The moisture is then effectively transported further north toward Korea and east toward the southern parts of China during the extreme rainfall period.

• 한국항해학회지
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• 제14권2호
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• pp.33-59
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• 1990

In cold season, the developed extratropical cyclones and associated cold fronts, and NW winter monsoon are encountered very frequently in the North Pacific, especially in the northwest part of it. The two sea areas, namely, the northwest part of North Pacific, especially the eastern area far off Japan east coast, and Burmuda Triangle in the North Atlantic are generally known as two of the most dangerous areas in the world because of high incidence of sea casualties. Even large ocean going vessels were sunk frequently due to strong winds and very high seas caused by NW monsoon or developed cyclones during the winter months. The purpose of this paper is to analyse the real state of heavy weather and high sea phenomena on the vesscls at sea, thus helping mariners operate in such conditions.

• Journal of Contemporary Eastern Asia
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• 제10권1호
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• pp.55-71
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• 2011

China has been experiencing high economic growth along with massive change in its industrial structure. How will the industrial structure change affect the Chinese economy? Similar changes were observed by Japan, when the Japanese banking system fell into a structural failure in terms of the inability to respond to the paradigm shift from "catching up" to "frontier economy." This paper is undertaken to highlight the lessons that China can learn from Japan's prolonged financial slump. We point out that big cities in China have already shifted to frontier economy and major provinces are on the same trend. We argue that in spite of economic reform reshaping the Chinese banking system, the financing pattern of state owned commercial banks (SOCB) is not in line with the industrial change. The Chinese banking system should be overhauled or transformed to respond to the increasing uncertainty along with the paradigm shift. Otherwise, China may fall into the same dilemma that Japan had faced in its industrial structure change.

• 한국환경과학회지
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• 제8권6호
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• pp.645-652
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• 1999

In order to simulate and investigate the major characteristics of El Nino/Southern Oscillation(ENSO) and Madden Jullian Oscillation(MJO), an intermediate type atmosphere-ocean coupled model is developed and their results are examined. The atmosphere model is a time-dependent non-linear perturbation moist model which can determine the internal heating for itself. The counterpart of the atmosphere model is GCM-type tropical ocean model which has fine horizontal and vertical grid resolutions. In the coupled experiment, warm SST anomaly and increased precipitation and eastward wind and current anomalies associated with ENSO and MJO are properly simulated in Pacific and Indian Oceans. In spite of some discrepancies in simulation MJO, the observed atmospheric and oceanic low-frequency characteristics in the tropics are successfully identified. Among them, positive SST anomalies centered at the 100m-depth of tropical eastern-central Pacific due to the eastward advection of warm water and reduced equatorial upwelling, and negative anomalies in the Indian and western Pacific seem to be the fundamental features of tropical low-frequency oscillations.

• 대기
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• 제27권3호
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• pp.277-290
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• 2017

Characteristics of precipitation in South Korea during the 2016 Changma period (6/18~7/30) are analyzed in great details. El $Ni{\tilde{n}}o$-induced tropical Indian Ocean (IO) basin-wide warming lasts from spring to early summer and induces the western North Pacific subtropical high (WNPSH) circulation anomaly through an equatorial Kelvin wave during the 2016 Changma period. Along the northern edge of the WNPSH, strong precipitation occurred, in particular, over eastern China and southern Japan. During the Changma period, South Korea had the near-normal mean precipitation amount (~332 mm). However, about 226 mm of rain fell in South Korea during 1 July to 6 July, which amounts to 67% of total Changma precipitation in that year. Upper-level synoptic migratory lows and low-level moisture transport played an essential role, especially from 1 July to 3 July, in triggering an abrupt development of fronts over the Korean Peninsula and the eastern continent China. The front over the eastern China migrates progressively eastward, which results in heavy rainfall over the Korean peninsula from 1 to 3 July. In contrast, from 4 to 6 July, the typhoon (NEPARTAK) affected an abrupt northward advance of the North Pacific subtropical high (NPSH). The northward extension of the NPSH strengthens the Changma front and induces the southerly flows toward the Korean peninsula, giving rise to an increase in heavy rainfall. The NEPARTAK is generated due to interaction of the Madden-Julian Oscillation (MJO), equatorial Rossby wave and Kelvin waves.

• Asian Pacific Journal of Cancer Prevention
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• 제16권14호
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• pp.5655-5661
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• 2015

Purpose: To assess the role of two adjuvant chemotherapy regimens, anthracycline-based and CMF on disease free survival and overall survival breast cancer patients by meta-analysis approach in Eastern Mediterranean and Asian countries to determine which is more effective and evaluate the appropriateness and efficiency of two different proposed statistical models. Materials and Methods: Survival curves were digitized and the survival proportions and times were extracted and modeled to appropriate covariates by two multivariate mixed effects models. Studies which reported disease free survival and overall survival curves for anthracycline-based or CMF as adjuvant chemotherapy that were published in English in the Eastern Mediterranean region and Asia were included in this systematic review. The two transformations of survival probabilities (Ln (-Ln(S)) and Ln(S/ (1-S))) as dependent variables were modeled by a multivariate mixed model to same covariates in order to have precise estimations with high power and appropriate interpretation of covariate effects. The analysis was carried out with SAS Proc MIXED and STATA software. Results: A total of 32 studies from the published literature were analysed, covering 4,092 patients who received anthracycline-based and 2,501 treated with CMF for the disease free survival and in order to analyze the overall survival, 13 studies reported the overall survival curves in which 2,050 cases were treated with anthracycline-based and 1,282 with CMF regimens. Conclusions: The findings illustrated that the model with dependent variable Ln (-Ln(S)) had more precise estimations of the covariate effects and showed significant difference between the effects of two adjuvant chemotherapy regimens. Anthracycline-based treatment gave better disease free survival and overall survival. As an IPD meta-analysis in the Italy the results of Angelo et al in 2011 also confirmed that anthracycline-based regimens were more effective for survival of breast cancer patients. The findings of Zare et al 2012 on disease free survival curves in Asia also provided similar evidence.

• Asian Pacific Journal of Cancer Prevention
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• 제15권21호
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• pp.9535-9541
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• 2014

Background: Identifying risk factors of breast cancer is a key point for preventive strategies to reduce the incidence. The aim of current study was to determine most important risk factors for breast cancer in the Eastern Mediterranean Region (EMR) using a systematic review. Materials and Methods: PubMed, Scopus, Web of Science till August 24, 2012 and the reference lists of all included studies were searched. Analytic studies which had reported odds ratios (OR), relative risk (RR) or required data to calculate them were included. A total of 343 studies were critically appraised and finally 30 studies were meta-analyzed. Heterogeneity between the studies was assessed by $I^2$ and Cochran's Q. Egger's test was used to assess publication bias. Results: Twenty five casecontrol studies, one nested case-control and four cohort studies were included. The largest ORs were obtained for history of no live birth (2.25; 95%CI: 1.58-3.18), body mass index (BMI) more than 30 (2.21; 95%CI: 1.71-2.36), age at first pregnancy more than 30 years old (1.52; 95%CI: 1.30-1.77) and meat consumption more than three times per week (1.39; 95%CI: 1.03-1.87). The other important predictors were higher education and smoking as risk factors, physical activity and ovulatory stimulating medication as protective factors. Conclusions: The most important predictors of breast cancer in EMR were history of no live birth, BMI more than 30, age at first pregnancy more than 30 years old, physical inactivity and smoking. Almost all these risk factors are consistent with known risk factors for this cancer in other parts of the world.

• 한국기후변화학회지
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• 제8권1호
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• pp.11-19
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• 2017

This study examined the relationship between the initiation timing typhoon season in the Northwestern Pacific and the tropical sea surface temperature (SST) using a numerical simulation. The initiation timing of the typhoon season is closely associated with SSTs over the Indian Ocean (IO) and the eastern Pacific (EP) in the preceding winter and early-spring. The experiment based on the Weather and Research Forecast (WRF) model showed that the start date of the typhoon season is delayed for about one month when the SSTs over the IO and the EP increase in the preceding winter. The forced tropical SST pattern induces anticyclonic anomalies in the Northwestern Pacific, which is an unfavorable condition for typhoon development, and hence it could delay the initiation of the typhoon season.