• Advances in Traditional Medicine
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• 제6권1호
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• pp.27-33
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• 2006

The Sasang constitutional medicine classifies the mankind into four constitutional types according to the individual psychological and physical traits. Differences in the Sasang constitutional medicine may be explained by the genetic factors. In order to determine the association of Sasang constitutional classification and interleukin-1 receptor antagonist (IL-1Ra) in genetic susceptibility to ischemic stroke, we classified the four constitutional types in ischemic stroke patients (n = 125) and the healthy control subjects (n = 107), and genotyped for IL-1Ra polymorphism by polymerase chain reaction (PCR) methods. The distribution of the $IL1RN^*1/IL1RN^*2$ genotype in the ischemic stroke patients was significantly different from the healthy controls (OR = 6.09; P =0.0134). And the prevalence of $IL1RN^*1/IL1RN^*2$ genotype was increased in Taeum-in ischemic stroke patients, as compared to Taeum-in healthy controls (OR = 14.71; P = 0.0144). These results suggest that $IL1RN^*1/IL1RN^*2$ genotype in Taeum-in might be associated with the increasing risk for ischemic stroke. Furthermore, this relationship could provide the basis for a new approach in the investigation of the etiology of ischemic stroke.

• 사상체질의학회지
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• 제22권2호
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• pp.60-69
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• 2010

1. Objectives: The purpose of this study was to analyze the serum lipid, digestive enzymes, thyroid hormone of each Sasang type groups which were classified by Sasang medicine specialist. 2. Methode: The subjects were 1084 (male:female=399:685) person with 371 of Taeeum type, 324 of Soeum type, 389 of Soyang type after the Sasang type classification. The blood samples of the 1084 subjects were to analyze the serum lipid(triglyceride, total cholesterol, HDL-cholesterol, LDL-cholesterol), digestive enzymes(lipase, amylase), thyroid hormone(T3, TSH). The general linear model (SPSS 12.0) were used for the analysis. 3. Results: Taeeum type group ($133.50\pm89.84$, $189.41\pm33.11$, $107.29\pm28.66$) showed significantly higher triglyceride, total cholesterol, LDL-cholesterol than other two group. In digestive enzymes(lipase, amylase), we found significant differences in the order of Soeum>Soyang>Taeeum. Soeum type group($116.23\pm21.38$) has lower T3 than Soyang type group ($119.90\pm21.60$) with marginal significance (p=0.066). 4. Conclusions: The Results of present study showed that Taeeum type showed significantly highest in triglyceride, total cholesterol, LDL-cholesterol. Soeum type showed significantly highest in digestive enzymes. Blood sample of each Sasang type group will serve as an important evidence for further study showing that the Sasang typology has biological basis.

• 사상체질의학회지
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• 제27권1호
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• pp.82-109
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• 2015

Objectives This research was proposed to present Clinical Practice Guideline (CPG) for Prevention of Sasangin disease pattern of Sasang Constitutional Medicine (SCM) and diseases closely related with Sasang constitution. Each CPG was developed by the national-wide experts committee consisting of SCM professors. Methods At first, we searched the literatures related to SCM such as "Dongeuisusebowon", Textbook of SCM and Clinical Guidebook of SCM. Also we searched the articles related to the studies about risk factors for Sasangin disease pattern of both at home and abroad. Finally, we selected leading risk factors of Sasangin disease pattern and developed CPG for prevention of Sasangin disease pattern of SCM. And then, we searched the literatures related SCM such as "Dongeuisusebowon" and the articles on the correlation between disease and Sasang constitution using case-control studies, observational studies or cross sectional studies of both at home and abroad. Next, we selected diseases closely related with Sasang constitution on the basis of articles including prevalence rate and odds ratio between disease and Sasang constitution and finally developed CPG for these diseases. Results and Conclusions We categorized risk factors of Sasang disease pattern into 2 types: non-modifiable and potentially modifiable. 3 items (age, sex and genetic factors) were classified as non-modifiable risk factors of Sasang disease pattern. 6 items (original symptom, stress, diet and nutrition, physical activity, alcohol and drug misuse) were classified as less well-documented or potentially modifiable risk factors of Sasangin disease pattern. We found out Sasang constitution is more likely to develop some diseases. It was proven that Sasang constitution increase the risk of hypertension, diabetes mellitus, metabolic syndrome, stroke, nonalcoholic fatty liver and obstructive sleep apnea. And there is high probability of Sasang constitution being potential risk factor for obesity, hyperlipidemia, allergy and cancer. Also, we found out Taeeumin is independent risk factor for hypertension, diabetes mellitus, metabolic syndrome, stroke, nonalcoholic fatty liver and obstructive sleep apnea. Therefore we recommend that Taeeumin need to prevent these disease by regular checkups and aggressive management.

• 사상체질의학회지
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• 제21권3호
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• pp.48-62
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• 2009

1. Objectives: The purpose of this study was to analyze the physical and psychological characteristics of each Sasang type groups which were classified by Sasang medicine specialist. 2. Methods: The subjects were 115 (85.2% of male) university students with $26.8\pm5.4$ yrs. of age and $12.9\pm1.7$ yrs. of education. We can get 30 of Soyang type, 39 of Taeeum type, 46 of Soeum type after the Sasang type classification. Their physical characteristics were measured with Bioelectrical Impedance Analysis (Inbody 720, Biospace, Seoul), and psychological characteristics with Temperament and Character Inventory (Maumsarang, Seoul). The general linear model (SPSS 12.0, SPSS Inc, Chicago) were used for the analysis with gender and age as covariance. 3. Results and Conclusions: Taeeum type group ($75.64\pm13.01$, $26.12\pm4.16$, $15.74\pm2.42$, $11.30\pm1.80$, $3.93\pm0.62$, $18.43\pm7.70$) showed significantly bigger weight, intra-cellular water, extra-cellular water, protein, mineral, body fat mass than Soeum type group ($61.32\pm8.56$, $22.54\pm3.87$, $13.70\pm2.15$, $9.74\pm1.68$, $3.35\pm0.51$, $10.79\pm3.97$). In obesity degree such as Body Mass Index and Waist-hip ratio, and circumference measures in chest, waist and hip, we found significant differences in the order of Taeeum>Soyang>Soeum. As a psychological perspectives Soyang type group ($41.90\pm13.32$) has higher NS (Novelty-Seeking) score than Soeum type group ($35.22\pm11.22$) with marginal significance (p=0.052). In sub-scale measurements Soeum type group ($10.61\pm3.69$) has significantly lower value than other two groups in P3 (Ambition). The results of present study showed that Taeeum type by specialist has same physical characteristics as previously reported QSCC II based studies. Temperament profile of each Sasang type group will serve as an important evidence for further study showing that the Sasang typology has biological basis.

• 동의생리병리학회지
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• 제30권6호
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• pp.426-431
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• 2016

Sasang Digestive Function Inventory (SDFI) and Sasang Personality Questionnaire (SPQ) were developed on the basis of clinical experiences of Korean medicine hospital and previous studies have used these for analyzing Sasang constitutional characteristics mainly in hospital level. The purpose of this study is to analyze Sasang constitutional characteristics using SDFI and SPQ in clinical level. The SPQ, SDFI, height and weight were measured with 79 patients over 18-years-old from Jan. 2015 to Apr. 2016 in the clinic, Daegu, Korea that specializes in tinnitus and performs Sasang constitution diagnosis. We used ANOVA in analyzing the differences of the scores of SPQ, SDFI, BMI and PI in each Sasang types (Tae-Yang, So-Yang, Tae-Eum), and Bonferroni test or Dunnett's T3 for post verification. The SDFI-T(F=3.215) and SDFI-D(F=4.347) scores were significantly different(p<0.05) and SPQ score was not different in each Sasang types(p>0.05). And Weight(F=4.294), BMI(F=12.386) and PI(F=14.490) were significantly different in each Sasang types(p<0.001). We found that SDFI(SDFI-D) and BMI PI can explain the Sasang constitutional characteristics, that is equivalent to previous studies and might be used for clinical index in making objective questionnaire for Sasnag constitutional diagnosis in clinical level.

• 셀메드
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• 제5권1호
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• pp.7.1-7.7
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• 2015

According to Ayurveda, an individual can be classified into any one of the seven constitutional types (Prakriti) depending on the dominance of one, two, or three Doshas. A 'Dosha' is representative of fundamental mechanisms that are responsible for homeostasis, and thus, to health. In the recent years, there have been several efforts to see whether certain physiological, haematological or biochemical parameters have any relationship with the constitutional types or not. The objective of the present study was to see if the results of autonomic function tests vary according to Prakriti of an individual. We conducted this study in clinically healthy volunteers of both the gender belonging to the age group of 17 to 35 years after obtaining their written consent. The Prakriti of these volunteers was assessed on the basis of a validated questionnaire and also by traditional method of interviewing. After confirming that the primary Dosha ascertained by both these methods matched, 106 volunteers were grouped into three on the basis of primary Dosha and were subjected to various autonomic function tests such as cold pressor test, standing-to-lying ratio, Valsalva ratio and pupillary responses such as pupil cycle time and pupil size measurement in light and dark. The results suggest that, the autonomic function tests in the healthy individuals may correlate linearly with the primary Dosha expressed in an individual. In particular, people with Kapha as the most dominant Dosha showed a tendency to have either a higher parasympathetic activity or a lower sympathetic activity with respect to their cardiovascular reactivity in comparison to the individuals with Pitta or Vata as the most dominant Dosha.

• 사상체질의학회지
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• 제10권1호
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• pp.25-40
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• 1998

Sasang Constitutional Medicine is the constition medicine and the basis which constitution reveals is the distinction of the nature and emotion. Therefore the theory of the nature and emotion is the foundation which Sasang Constitution Medicine is coming into being. The author studied the progress that the distinction of the nature and emotion was formed and analized the phenomenon presented by the distinction of it as the principle of the movement of Yin and Yang. The results are following; 1. The beginning of the operation of the nature begins from some one part(cho ; 焦) among four part. That consists of the first factor of constitution-revelation. In accordance with the distinction of the nature, the second factor, that is the distinction of the emotion is determined and the united distinction of the nature and emotion presents the Sasang constitution. 2. The operation of the nature and emotion is the movement of Qi by the property of Yin and Yang and that is the phenomenon presented by the logical and scientifical law. 3. The ontology of Lee Je-ma is Qi-monism. 4. Four emotion(Sorrow, Anger, Joy, Presure) are not partional concept of the emotion but total concept which include all of it.

• 사상체질의학회지
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• 제10권2호
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• pp.291-304
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• 1998

This thesis on the basis of the "Sasang"(the four classification by the physical constitution) that becomes the focus of the public interest in Korea intends to grasp a color image and serve basic materials for the color usage in the interior design planning. It tries to identify the relationship between physical constitution and color. The color planning for experiment plans to be related to Korean traditional color. Analysis result on color and color image to patterns of interior color shows that the physical constitution in measure difference is bigger than sex among the many image evaluation items. Therefore, the interior color preference of Korean is bright hue and tint such as warm and cool color.

• 사상체질의학회지
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• 제11권2호
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• pp.341-359
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• 1999

1. 연구 목적 양생(養生)을 중시하는 사상의학(四象醫學)에 있어서 체질식이요법은 체질진단, 약물치료에 못지 않게 중요하다. 하지만 체질별 식이요법의 중요성에도 불구하고 학자들간에 체질음식에 대한 이견(異見)으로 인하여 혼란이 있어왔던 것도 사실이다. 따라서 식품 각각에 대한 역사적 유래, 특성, 효능에 대한 문헌고찰을 통하여 사상체질 식이요법의 이론적 배경을 제시할 필요성이 제기된다. 고려 때 상추쌈 문화를 원(元)나라에 전파시켰던 우리 나라에서 상추는 꼭 필요한 야채 중의 하나로 채소의 대장이라 할 수 있다. 상추는 백거, 와거, 고거 등으로 표기되었는데, 사실상 같은 식물이라 할 수 있다. 그러나 고거는 고채(苦菜)의 이명(異名)으로도 사용되었기 때문에 용어의 혼란이 있어왔다. 또한 고채(苦菜)가 어느 식물을 지칭하는 지에 대하여서도 논란의 소지가 있다. 따라서 본고에서는 상추와 고채(苦菜)를 같이 고찰하였다. 2. 연구 방법 본초서(本草書) 뿐만 아니라 농서(農書), 유서(類書), 개인문집 등을 비교 분석하였다. 3. 연구 결과 (1) 인조(仁祖) 11년(1633) "향약집성방(鄕藥集成方)"이 중간(重刊)되면서 백거의 두주(頭註)로 붙여진 사나부노(斜羅夫老)는 와거(부로)일 가능성도 있으나, 곡곡채(曲曲菜)인 사데풀(S brachyotus A.P. DC.)을 지칭하는 것으로 보아야 한다. 따라서 백거의 향명(鄕名)으로 사나부노(斜羅夫老)가 쓰여진 것은 오류일 가능성이 높다. (2) 상추는 생채(生菜)에서 나온 단어로 '자부두(紫夫豆) ${\rightarrow}$ 부루, 부로, 부로(阜蘆) ${\rightarrow}$생채(生菜)(상채, 상취, 상춰, 상치) ${\rightarrow}$ 상치 ${\rightarrow}$상추'의 과정을 거쳐 오늘날의 상추가 되었다. (3) 상추가 고려국(高麗國)에서 중국으로 갔다는 것은 괘를 고(高)로 잘못 쓰는 바람에 나타난 오류이다. (4) 한성(寒性)이 있는 상추를 금(金)기운으로 보았기 때문에 적상추보다 백상추가 좋으며 가을에 먹으면 좋다고 본 것이다. (5) 상추가 도입된 이후 고거를 주로 설명하였지만 1500년대 말(末) 이후 우리 나라에서는 와거 만을, 중국에서는 백거와 와거를 각각 설명하는 경향을 보인다. 또한 "동의보감(東醫寶鑑)"의 와거는 이전(以前) 의서(醫書)에 나오는 백거의 효능설명과 일치하고 있다. (6) 상추는 소양인의 갈 흉격열증(胸膈熱症)에 응용될 수 있는 식품이다. (7) 시골집 장독대 옆에 상추밭을 조성하는 까닭은 염분이 필요한 뱀의 접근을 막고자 한 것으로 매우 합리적이다. (8) 무더운 여름에 상추파종시 저온처리를 통하여 휴면타파가 가능하다. 이는 한성(寒性)이 있는 상추에 인위적으로 서늘한 기운을 주는 것으로 해석된다. (9) 의서(醫書)와 농서(農書)에서는 고채(苦菜)를 고들빼기, 유서(類書)에서는 씀바귀로 번역하고 있으며. "본초강목(本草綱目)"의 고채(苦菜)의 효능은 "증류본초(證類本草)"의 고거와 고채(苦菜)를 합하여 설명하고 있다.

• 사상체질의학회지
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• 제33권3호
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• pp.87-94
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• 2021

Objectives The purpose of this study is to examine the meaning of the Soeumin's Softness and Non-softness in the mouth(口中和, 口中不和). Methods We examined The Existing Doctors's using of the Softness and Non-softness in the mouth, and considered Jema Lee's using of the Softness and Non-softness in the mouth. Afterward, we considered the meaning of the Soeumin's Softness and Non-softness in the mouth in 『Donguisusebowon(東醫壽世保元)』. Results and Conclusion 1. Junggyeong Jang used the Softness in the mouth, and he didn't use the Non-softness in the mouth in 『Sanghanlun(傷寒論)』. 2. The Next Generation Doctors used the Softness in the mouth, and they didn't use the Non-softness in the mouth. Especially, Dongwon Lee used the Softness in the mouth as the Knowing the taste of food, and used the Non-softness in the mouth as the Non-knowing the taste of food. 3. Jema Lee used the Softness and Non-softness in the mouth as urgent indicator of the Soeumbyeong diarrhea in 『Gabobon(甲午本)』, and used the Softness and Non-softness in the mouth as classification indicator of the Taeeumbyeong and Soeumbyeong in 『Sinchuckbon(辛丑本)』. 4. The Non-softness in the mouth is Jema Lee's specific term. It means dry of mouth, thirsty and the Non-knowing the taste of food. 5. The change from the Non-softness to Softness in the mouth is recovery indicator of the Soeumin's disease. It is the basis for setting the Drinking water(能飮水) as the Soeumin's igiljeung(二吉證).