• Journal of Nutrition and Health
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• 제37권9호
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• pp.825-837
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• 2004

Studies on the health problems of the elderly have been increased with increasing life expectancy of Koreans. To assess the health status of people over 50 years old including the elderly (678 free-living people: men (168), women (510)), anthropometric measurements and biochemical nutritional status were analyzed. General characteristics and the prevalences of specific diseases were also examined. The mean anthropometric values for males and females were heights of 162 cm and 149 cm, respectively; and weights of 59 kg and 52 kg, respectively, which were much lower than the Korean standards established in the Korean Recommended Dietary Allowances. The mean BMI, WHR (waist hip ratio), and body fat rate (%), which are obesity indices, were significantly higher in females than in males. As the age went up, height, weight, lean body mass, and mid-arm circumference decreased. Whereas, blood pressure (SBP) for women increased. Mean blood HDL-cholesterol levels of men and women were 46.0 mg/dl and 46.3 mg/dl, respectively; their triglyceride levels were 129.1 mg/d1 and 135.6 mg/dl, respectively, which were not significantly different. Total cholesterol and LDL-cholesterol levels were significantly higher in females than in males. For man there were significantly different in ${\gamma}$-GTP, Na levels by age. As the age went up for women, RBC, hemoglobin, hematocrit, HDL-cholesterol, ${\gamma}$-GTP and $Ca^{2+}$ levels significantly decreased. Levels of total protein and albumin were above the lower normal limit for the majority of the participants. Prevalence of anemia, assessed by hemoglobin using World Health Organization (WHO) definition, was 43.9% for men and 42.1% for women. Also, many of the subjects were out of the normal range in total cholesterol (women), HDL-cholesterol, TAS (total antioxidant status), APase, RBC, hemoglobin, hematocrit levels. Therefore, measures to improve the biochemical nutritional status for the people in rural area are required.d.

• 한국치위생학회지
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• 제20권1호
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• pp.95-106
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• 2020

Objectives: This study was conducted to investigate the effects of dental hygienists' job satisfaction on turnover intention and intention to stay. Methods: A survey was conducted targeting 273 dental hygienists in dental clinics. The study data were u analyzed using PASW Statistics 20.0 Results: The level of job satisfaction of dental hygienists was 3.30±0.50, and the highest ranked item in the survey was 'I am satisfied with my relationships with patients' 3.72±0.73. Job satisfaction according to general characteristics showed significant differences in age, marriage, education, career, current work experience, position, and schedule for future turnover. The turnover intention according to general characteristics showed significant difference in age and schedule for future turnover. The intention to stay according to general characteristics showed significant differences in age, marriage, education, career, current work experience, number of dentists, number of dental hygienists, and schedule for future turnover. The factors affecting turnover intention were schedule for future turnover, income, co-worker relation and professional time, while those affecting intention to stay were overall professional satisfaction, co-worker relation, schedule for future turnover, professional time, income, number of dental hygienists, patient relations and current work experience. Conclusions: Job satisfaction factors that had a common effect on turnover intention and intention to stay were schedule for future turnover, income, co-worker relation and professional time. To reduce turnover and encourage longevity, adequate pay and positive interpersonal relationships are necessary.

• Journal of Microbiology and Biotechnology
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• 제25권8호
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• pp.1195-1204
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• 2015

Increasing evidence suggests that gut microbiota underpin the development of health and longevity. However, our understanding of what influences the composition of this community of the longevous has not been adequately described. Therefore, illumina sequencing analysis was performed on the gut microbiota of centenarians (aged 100-108 years; RC) and younger elderlies (aged 85-99 years; RE) living in Bama County, Guangxi, China and the elderlies (aged 80-92 years; CE) living in Nanning City, Guangxi, China. In addition, their diet was monitored using a semiquantitative dietary questionary (FFQ 23). The results revealed the abundance of Roseburia and Escherichia was significantly greater, whereas that of Lactobacillus, Faecalibacterium, Parabacteroides, Butyricimonas, Coprococcus, Megamonas, Mitsuokella, Sutterella, and Akkermansia was significantly less in centenarians at the genus level. Both clustering analysis and UniFraq distance analysis showed structural segregation with age and diet among the three populations. Using partial least square discriminate analysis and redundancy analysis, we identified 33 and 34 operational taxonomic units (OTUs) as key OTUs that were significantly associated with age and diet, respectively. Age-related OTUs were characterized as Ruminococcaceae, Clostridiaceae, and Lachnospiraceae, and the former two were increased in the centenarians; diet-related OTUs were classified as Bacteroidales, Lachnospiraceae, and Ruminococcaceae. The former two were deceased, whereas the later one was increased, in the high-fiber diet. The age and high-fiber diet were concomitant with changes in the gut microbiota of centenarians, suggesting that age and high-fiber diet can establish a new structurally balanced architecture of gut microbiota that may benefit the health of centenarians.

• 생명과학회지
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• 제28권8호
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• pp.931-937
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• 2018

뇌공등에 함유되어있는 트립톨라이드는 뛰어난 항염증, 항산화 효능을 가지고 있음이 보고되었다. 예쁜꼬마선충을 이용한 이전 연구에서 트립톨라이드의 섭취가 개체의 항스트레스 효능을 높이고, 수명을 연장시킴이 밝혀졌다. 본 연구에서는 트립톨라이드에 의한 수명연장에 관여하는 세포 내 기전과 트립톨라이드가 노화관련 질환인 당뇨병과 알츠하이머병에 미치는 영향을 평가하였다. 트립톨라이드는 인슐린/IGF-1-like 신호전달 저하에 의한 수명연장 돌연변이인 age-1과 미토콘드리아 전자 전달계 저하에 의한 수명연장 돌연변이인 clk-1의 수명을 유의적으로 증가시킨 반면, 식이제한 유도 돌연변이인 eat-2의 수명에는 유의적인 변화를 유도하지 못했다. 또한 박테리아 희석을 이용한 식이제한에 의해 연장된 수명을 추가적으로 더 연장시키지 못했다. 트립톨라이드 섭취는 고농도의 당 섭취에 의한 체내 독성과 사람 아밀로이드 베타 형질전환 유전자로 인한 체내 독성을 유의적으로 저하시켰다. 이러한 결과들은 트립톨라이드에 의한 수명연장이 식이제한에 의한 수명연장 기전과 중복되며, 트립톨라이드가 노화관련 질환을 저해하는 효능이 있음을 보여준다. 따라서, 트립톨라이드는 식이제한 효능을 대체할 수 있는 식의약품 개발에 활용될 수 있다.

• 한국식품영양과학회지
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• 제33권4호
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• pp.668-678
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• 2004

고령인구 비율이 높은 지역에 거주하는 성인 469명을 대상으로 24시간 회상법을 통해 1년 간 4계절의 식이섭취 조사를 하여 영양 섭취 상태를 양ㆍ질의 평가와 함께 계절적인 차이를 살펴본 결과 다음과 같았다. 조사 대상자의 연평균 1일 열량 섭취량(%RDA)은 1313.3$\pm$334.7 ㎉(72.0%)이며, 단백질은 47.3$\pm$17.0 g(82.2%)으로 남녀간에 권장량 대비 백분율에 유의한 차이가 없었다. 지방과 탄수화물, 식이 섬유소는 각각 20.2$\pm$12.8 g, 228.0$\pm$48.3 g, 12.8$\pm$4.5 g을 섭취하였으며, 남녀간에 유의적인 차이가 있었다. 비타민 및 무기질의 섭취량은 대부분 권장량 수준에 못 미쳤으며, 특히 칼슘, 비타민 B$_2$, 비타민 E, 비타민 D의 섭취는 권장량의 약 50%로 섭취율이 매우 낮았다. 성별에 따라서는 여성이 남성보다 비타민 및 무기질의 섭취량이 낮았으며, 계절별로는 대부분의 비타민과 무기질의 섭취율이 봄에 높았는데 예외적으로 비타민 C는 가을과 겨울에 섭취율이 높았다. 콜레스테롤의 섭취량은 남녀 각각 151.7$\pm$162.0 mg, 124.3$\pm$147.7 mg 이었으며 PUFA : MUFA : SFA의 비율은 1.0 : 1.3 : 1.2이었다. 탄수화물, 단백질, 지방 구성비율(CPF)은 72.7 : 14.4 : 12.9로, 성별에 따라서 탄수화물 에너지 구성비는 여자가 높았으며, 단백질 에너지 구성비는 남자가 높았다. 계절에 따라서는 남녀 모두 봄에 탄수화물 에너지 구성비율이 낮은 반면 단백질 에너지의 구성비율은 높았다. 대부분의 영양소 적정도는 0.8∼0.6의 범위였으나 칼슘, 비타민 A, 비타민 B$_2$, 비타민 E의 경우 0.5내외의 비율을 나타내었다. 성별에 따라서 단백질을 제외한 모든 영양소에서 여자보다 남자가 적정도에서 유의적으로 높았다. 평균 적정도는 0.66으로 다른 계절에 비해 남자는 봄에 높았고, 여자는 봄과 여름에 유의적으로 높았다. 영양의 질적 지수(INQ)는 칼슘, 비타민 A, 비타민 B$_2$, 비타민 E에서 1을 하회하였으며, 단백질을 제외한 모든 영양소에서 남자가 여자보다 질적 지수가 유의적으로 높았다. 계절에 따른 질적 지수는 남녀 모두 비타민 A와 나이아신은 봄에 높은 반면 비타민 C는 가을과 겨울에 유의적으로 높았다. 이와 같은 연구 결과로 볼 때 고령인구 비율이 높은 지역의 주민들은 전체적인 영양소 섭취 상태는 대부분의 영양소에서 권장량에 미달하여 양적으로 매우 부족한 실정이나, 질적인 영양섭취 평가 즉 영양소 적정도 및 평균 적정도, 영양의 질적 지수는 칼슘, 비타민 A, 비타민 B$_2$, 비타민 E를 제외하고 적절한 상태를 보였다. 또한 남녀를 비교할 때 여성이 남성보다 양적 질적 영양소 섭취 평가에서 낮은 상태를 보였다. 계절적으로는 다른 계절에 비해 봄에 영양소 섭취 상태가 좋았고 겨울에 불량한 것으로 나타나 본 연구 지역 주민들은 계절에 따라 영양소 섭취에 대해 영향을 받고 있음을 알 수 있었다. 따라서 전체적으로 열량 및 영양소 섭취량의 증가와 함께 질적으로 부족한 영양소의 섭취량을 증가시키고, 농촌의 특성을 고려하여 계절 식품을 잘 활용할 수 있도록 적절한 식품의 선택과 조리 방법에 대한 교육이 이루어져야 하며, 이러한 영양교육은 상대적으로 영양상태가 취약한 여성에게 우선적으로 실시되어야 하겠다. 그리고 앞으로 미량영양소의 정확한 평가를 위해 더 많은 식품성분 데이터베이스를 구축하고 보완하는 작업이 이루어져야 하겠다.

• 대한지역사회영양학회지
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• 제15권3호
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• pp.308-328
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• 2010

As the older adult period $({\geq}65y)$ is increasing, it is needed to investigate the trend of aging-dependent anthropomeric index and nutrient intake, and establish the more specific dietary guide for the different stages of aging period. To find the difference in nutrient intake among the Koreans aged 50-64, 65-74 and 75 years and older, and also any characteristics of dwellers in longevity area, we recruited 1,083 subjects (385 male and 698 female) aged 50-95 years (mean age, 71.3 yrs) living in Kugoksoondam area (Kurye, Goksung, Soonchang and Damyang counties), known as a longevity-belt region in Jeonlaprovince, Korea. We measured some anthropometric index and collected 2 day-dietary record. Nutrient intakes were analyzed by using DW24 program. The mean height and weight of subjects aged 75 years and older were lower than Korean national reference. BMI and obesity $({\geq}25kg/m^2)$ prevalence were significantly decreasing with aging. Underweight $(BMI<18.5kg/m^2)$ prevalence was also increasing with aging, especially in males, and it was slightly higher than national average, but similar to that in some other rural area. Obesity prevalence of male subjects was lower compared to national prevalence, but abdominal obesity prevalence $(waist{\geq}80cm)$ was very high in females (about 89%). In both genders, the average proportional contribution of carbohydrate, protein and fat to energy intake was not different between 65-74 years and 75 years and older. On overall, nutrient intake and quality of diet of females were inferior to those of males so that many of females aged 75 years and older assumed to be at risk of malnourished status. Fiber, folate and vitamin E intakes were substantially higher compared to those in 2007 KNHNES and other some studies in rural area. While almost nutrient %EAR was significantly decreased with aging in females, there was no significant difference in %EAR for protein, vitamin A, $B_1$, $B_6$, $B_{12}$, niacin, Ca and Zn between 65-74 years and 75 years and older in males. Vitamin $B_2$ for male aged 50-64 years, vitamin $B_2$ and Ca for male aged 65 years and over and female aged 50-74 years, and vitamin $B_2$, vitamin C, Ca and folate intake for female aged 75 years and older were assessed to be at risk to undernutrition based on the prevalence of intake below EAR. MAR of 13 nutrients and the number of nutrients consuming below EAR were significantly decreasing with aging in both genders, however, the number of nutrients of INQ < 1 and the average mini-nutritional assessment score were not significantly different between 65-74 years and 75 years and older. Taken together, decreasing tendency of nutrients intake and the quality of diet with aging was more evident in females than in males, and it is unique that our subjects consumed substantially higher fiber, folate and vitamin E compared to not only urban but also some other rural areas.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2011년도 제42회 하계학술대회
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• pp.2152-2153
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• 2011

According to a sharp increase in demand for electricity supply secure, and $CO_2$ regulation in accordance with global environmental problems and to solve problems, etc. These factor less pollution, higher energy conversion hyoyulin way that the new electrical equipment, nano-composites The rapid degeneration of the unit study utilizing the power that is required is Free. Accordingly, cables, transformers and switchgear (GIS)-capacity of power equipment, such as, high-voltage high-density along with the miniaturization of equipment have made angry the reliability of these devices is becoming a very important issue. Insulation materials used in electrical equipment for high voltage withstand, power equipment, power equipment due to aging and overloading caused by a weakening of the insulation failure and replacement in accordance with the age due to increased costs because of the reliability of electrical equipment should be secured should. Therefore, improved performance and longevity of insulation material is recognized as an important challenge. In this study, power isolation and degeneration of the unit for use in various parts of the molding epoxy resin to improve the insulation performance of the epoxy resin by varying the added amount of nano-SiO2 nanocomposites made epoxy/SiO2 analysis and breakdown properties of the experiment want to improve the electrical properties through the geometry.

• Asian-Australasian Journal of Animal Sciences
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• 제7권2호
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• pp.261-264
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• 1994

The lactation milk yields of 209 buffaloes and cattle were measured on farms in Taplejung and Dhankuta Districts in East Nepal. This includes local and crossbred buffaloes and cows. The average milk yield (${\pm}\;SD$) of 97 local buffaloes was $833\;{\pm}\;94.6\;kg$ whereas that for 83 local cows was only $455\;{\pm}\;61.5\;kg$. The milk yield of buffaloes decreased with number of calvings, but that for the cows increased. The milk yields of 18 Murrah crossbreds were on average 215 kg higher than the yields of local buffaloes, and the yields of 11 Jersey crossbred cows averaged 247 kg more than the local cows. Lactation length (${\pm}\;SD$) which averaged $326\;{\pm}\;100$ days for the buffaloes and $292\;{\pm}\;98$ days for the cows, was not affected by crossbreeding. The milk yields of the crossbreds were more variable than the local buffaloes and cows. In addition to milk yield the overall productivity of a milking animal depends on calf mortality, age at first calving, calving interval, longevity, food intake, the work performance of male cattle and the meat production of male buffaloes. Among these parameters, the work performance of Jersey crossbred and local male cattle was studied later. However, other factors could not be measured.

• 보건행정학회지
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• 제16권4호
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• pp.147-168
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• 2006

Technological innovation has been regarded as the core competence for the economic growth of individual, as well as organization and country. Pharmaceutical innovation, what we call new medicines, influence people's longevity and productivity by increasing output per hour worked. Therefore, using claims data on virtually all the drugs and diseases of over 550,000 people enrolled in National Health Insurance Program in Korea, we examined the impact of the vintage (original FDA and KFDA approval year) of drugs used to treat a patients from July 1st to December 31st in 2002 on the patient's mortality at the end of 2004, controlling for demographic characteristics(age and sex), utilization of medical services, and the nature and complexity of illness. We found that people using newer drugs are less likely to die at the end of 2004, conditional on covariates. The estimated mortality rates were declining with respect to drug vintage for 1970s, 1980s and 1990s and highly significant. In addition to estimating the model for the entire sample, we estimated the model separately for several disease categories classified by Korean Classification of Disease. Estimates of three drug vintage variables for subgroups of people with (1)neoplasms, (2)endocrine, nutritional and metabolic diseases, and (3)the diseases of circulatory system displayed similar patterns.

• The Korean Journal of Ecology
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• 제7권4호
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• pp.185-193
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• 1984

Regneration process of Abies koreana-Pinus koraiensis community consisted of a subalpione coniferous forest in Mt. Jiri, Korea, was studied in relation to age structure, especially to gap formation. The tall-tree layer (ca. 6.5m) is dominated by Abies koreana and Pinus koraiensis, while lower layer by the sapling and juveniles of A. koreana and Picea jezoensis below 2m tall. The ranges of DBH in A. koreana, P. koraiensis and P. jezonesis were 11.8cm~26.4m, 11.7cm~24.5 cm and 18.2cm~21.7 cm, respectively. The trees below 130 cm tall had contagious distribution, while tall and subtall trees had uniform distribution. The average tree ages of A. koreana, P. koraieniensis and P. jezoensis were 60~70 years, 70~80 years and 70~90 years, respectively. The saplings and juveniles below 20 years in tree ages were occupied over 80% of total trees. The coniferous trees in the gaps or around dead trees were composed of sapligs and juveniles which had emerged or invaded about 20 years before and after the gap formation. The Betula type regeneration of the coniferous forest took place in gaps which orginated from the failing down of a single or a few trees by longevity. Accordingly, it is clear that the subalpine coniferous forest composed of A. koreana of A. koreana, P. koraiensis and P. jezoensis in Mt. jiri was supporting by the regeneration pattern of Betula type.