• 천문학회보
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• 제36권2호
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• pp.125.1-125.1
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• 2011

After a short description of the observatory, this presentation will highlight some of the most recent scientific achievements based on CFHT observations and how they benefit from the current instrumentation and novel observing modes proposed to the CFHT users. We will then move to the mid-term future with the development of new spectroscopic capabilities (visible wide-field FTS or near-IR spectro-polarimetry) and the study of a novel wide-field imager in the visible using Ground-Layer AO to provide unprecedented image quality on a large field of view. As an option for the long-term future, the concept of a next generation 10-m class telescope to replace the current CFHT 3.6-m will be described. An emphasis will be given on how CFHT is slowly morphing into an Asia-Pacific Rim observatory and on the role the Korean community could play in such an endeavor, from immediate access to first-class astronomical data to partnering with other nations in exciting developments.

• Steel and Composite Structures
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• 제5권5호
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• pp.395-405
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• 2005

This work introduces to the international scientific community the Chinese Code on fire safety design of steel building structures. The aim of the Code is to prevent the structure of a steel building subjected to fire from collapsing, ensure safe evacuation of building occupants, and reduce the cost for repairing the damages of the structure caused by fire. The main contents of the Code is presented in this paper, including the fire duration requirements of structural components, fundamental requirements on fire safety design of steel components, temperature increasing of atmosphere and components in fire, loading effect and capacity of various components in fire, and procedure for fire-resistant design of steel components. The analytical approach is employed in the Code and the effectiveness of the Code is validated through experiments.

• 천문학회보
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• 제38권1호
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• pp.68.1-68.1
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• 2013

The K-GMT group launches a new science program designed to promote the observational research capabilities of Korean Astronomical Society. The science program (SP, hereafter) will provide the access to the observational facilities that is required for the completion of science proposals selected based on their scientific merits. The SP will invite the submission of proposals from all members of Korean Astronomical Society annually starting from mid-2013. We will introduce the rationale, action plan, and major timelines for the new K-GMT SP to the Korean astronomical community members.

• 구강회복응용과학지
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• 제21권2호
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• pp.191-204
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• 2005

Traditionally, the implant treatment require load-free healing period of at least 3 months in the mandible and 6 months in the maxilla. But this long healing period provides patients with the discomfort and economical trouble. Many experiments has been attempted for the outcome of such disadvantage, so recently the immediate loaded implant is getting popularity. Several literature has been published for clinical success of immediate loaded implant. The studies for the success rate of immediate loaded implant in multi-way has been reporting, nevertheless, we don't have yet a probable success. Various studies have been practiced that the advantages and disadvantages associated with immediate loaded implant, and factors that may influence the success of immediate implant, including patient selection, type of bone quality, required implant length, structure of the implant, surgical skill, need for achieving primary stability, control of occlusal force, peri-implant bone activity. The objective of this study is to review the literature related to immediate loading of implants and to discuss factors that may influence this treatment modality, based on scientific evidence.

• 한국지능정보시스템학회:학술대회논문집
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• 한국지능정보시스템학회 2004년도 추계학술대회
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• pp.361-368
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• 2004

The purpose of the study was to explore the potential of the Social Network Analysis as an analytical tool for scientific investigation of learner-learner, or learner-tutor interaction within an Computer Supported Corporative Learning (CSCL) environment. Theoretical and methodological implication of the Social Network Analysis had been discussed. Following theoretical analysis, an exploratory empirical study was conducted to test statistical correlation between traditional performance measures such as achievement and team contribution index, and the centrality measure, one of the many quantitative measures the Social Network Analysis provides. Results indicate the centrality measure was correlated with the higher order learning performance and the peer-evaluated contribution indices. An interpretation of the results and their implication to instructional design theory and practices were provided along with some suggestions for future research.

• 한국농공학회논문집
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• 제61권2호
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• pp.51-61
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• 2019

In this study, interest in rural life of good natural environment rather than busy life is increasing as human life is extended by scientific and medical technology and society has improved. The reckless development of rural villages has caused social problems as the natural environment has been damaged, failing to function as a pleasant home. To address these problems, the government has implemented a rural village development project, but if the site is selected incorrectly, the residents may not be recruited, or applicants may lose their status, or the portion of the infrastructure building fee may increase. In order to prepare objective and clear assessment methods for the target site not to cause such problems, a layering analysis method (AHP: Analytic Method) was used to identify the current status of the rural village formation project, draw assessment items, and determine the importance of each item.

• Asian Pacific Journal of Cancer Prevention
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• 제13권4호
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• pp.1705-1708
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• 2012

The inception of targeted agents has revolutionized the cancer therapy paradigm, both for physicians and patients. A large number of molecular targeted agents for cancer therapy are currently available for clinical use today. Many more are in making, but there are issues that remain to be resolved for the scientific as well as social community before the recommendation of their widespread use in may clinical scenarios can be done, one such issue being cost and cost effectiveness, others being resistance and lack of sustained efficacy. With the current knowledge about available targeted agents, the growing knowledge of intricate molecular pathways and unfolding of wider spectrum of molecular targets that can really matter in the disease control, calls for only the just use of the agents available now, drug companies need to make a serious attempt to reduce the cost of the agents. Research should focus on agents that show sustained responses in preclinical data. More needs to be done in laboratories and by the pharmaceutical industries, before we can truly claim to have entered a new era of targeted therapy in cancer care.

• Asian Pacific Journal of Cancer Prevention
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• 제16권8호
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• pp.3587-3590
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• 2015

In spite of limited data regarding the safety or effectiveness of electronic cigarette introduced into the market as a healthier alternative to tobacco smoking, its popularity has increased enormously. E-cigarettes have penetrated the market rapidly owing to the elaborate marketing network and attractive marketing strategies. Stated advantages include the claim that they help quit smoking and produce less exposure than conventional smoking. The list of disadvantages is even more elaborate. While the majority of the studies supporting health claims and efficacy for quitting smoking are not scientifically sound, they are also challenged by studies providing contradictory results. Owing to the limited evidence on the potential advantages and disadvantages of e-cigarettes, the debate on their safety continues.

• International Journal of Advanced Culture Technology
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• 제8권2호
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• pp.28-33
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• 2020

The Chemist Antoine-Laurent Lavoisier and mathematician Pierre Simon Laplace, who conducted a collaborative research on heat phenomena, are two of the key figures that represent French scientific community in the late 18th century. They joined hands together to understand heat phenomena that had not been fully explained until that time. They studied heat phenomena based on a heat particle model called 'caloric' and this study further expanded into light, magnetism and electricity, laying groundwork for many other research achievements afterwards. This article goes through their individual researches and looks into the process of their joint research based on the analysis of their publications. Further to these, it emphasizes its continuity with the Laplacian Program, a large-scale research project conducted in the early 19th century. Lastly, this article presents how science can merge with history, and at the same time, introduces the prerequisites for successful convergence research through existing research cases.

• BMB Reports
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• 제48권5호
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• pp.266-270
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• 2015

Over the last decade, comprehensive genome-wide sequencing studies have enabled us to find out unexpected genetic alterations of metabolism in cancer. An example is the identification of arginine missense mutations of isocitrate dehydrogenases-1 and -2 (IDH1/2) in glioma, acute myeloid leukemia (AML), chondrosarcomas, and cholangiocarcinoma. These alterations are closely associated with the production of a new stereospecific metabolite, (R)-2-hydroxyglutarate (R-2HG). A large number of follow-up studies have been performed to address the molecular mechanisms of IDH1/2 mutations underlying how these events contribute to malignant transformation. In the meanwhile, the development of selective mutant IDH1/2 chemical inhibitors is being actively pursued in the scientific community and pharmaceutical industry. The present review article briefly discusses the important findings that highlight the molecular mechanisms of IDH1/2 mutations in cancer and provides a current status for development of selective mutant IDH1/2 chemical inhibitors. [BMB Reports 2015; 48(5): 266-270]