• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.47 no.6
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• pp.445-453
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• 2021

Objectives: Periodontitis is the most common chronic disease that causes tooth loss and is related to systemic diseases such as cardiovascular disease and diabetes. An objective indicator of the current activity of periodontitis is necessary. Soluble forms of the receptor for advanced glycation end products (sRAGE) are markers that reflect the status of inflammatory diseases. In this study, the relationship between sRAGE and periodontitis was analyzed to determine whether it can be used to diagnose the current state of periodontitis. Patients and Methods: Eighty-four patients without any systemic diseases were diagnosed with periodontitis using three classifications of periodontitis. Demographics and oral examination data such as plaque index (PI), bleeding on probing (BOP) index, and probing pocket depth (PPD) were analyzed according to each classification. In addition, correlation and partial correlation between sRAGE and the values indicating periodontitis were analyzed. Results: In each classification, the level of sRAGE tended to decrease if periodontitis was present or severe, but this change was not statistically significant. sRAGE and periodontitis-related variables exhibited a weak correlation, among which the BOP index showed a relatively strong negative correlation (ρ=-0.20). Based on this, on analyzing the correlation between the BOP index and sRAGE in the group with more severe periodontitis (PPD≥5 mm group, severe group of AAP/CDC [American Academy of Periodontology/Centers for Disease Control and Prevention], periodontitis group of López), the correlation further increased (ρ=-0.23, -0.40, -0.50). Partial correlation analysis of the sRAGE and BOP index showed a stronger negative correlation (ρ=-0.36, -0.55, -0.45). Conclusion: sRAGE demonstrated a tendency to decrease upon increased severity of periodontitis according to the classifications used. Above all, the correlation with the BOP index, which reflects the current state of periodontitis, was higher in the group with severe periodontitis. This indicates that the current status of periodontitis can be diagnosed through sRAGE.

• Journal of Korean Academy of Oral Health
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• v.42 no.4
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• pp.101-108
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• 2018

Objectives: The Korea National Health and Nutrition Examination Survey (KNHANES) is a national surveillance system that has been assessing the health and nutritional status of Koreans since 1998. Based on the National Health Promotion Act, the surveys have been conducted by the Korea Centers for Disease Control and Prevention (KCDC). Methods: An oral examination as part of The National Health and Nutrition Examination was proposed to calculate the sample design and survey participation. The surveying system was presented by classifying the measurement environment, screening, and survey items by year, and the merits and limitations of using the data were suggested by examining the status of survey quality management and the process of disclosing raw data. Results: This nationally representative cross-sectional survey samples approximately 10,000 individuals each year and collects information on oral examinations and oral health interviews. Data for the oral health component of KNHANES was obtained to assess the oral health status of Koreans and determine the prevalence of dental caries and periodontitis. The oral health data quality control of KNHANES was composed of three parts: "Education Program" and "Field Training Program" for quality control of oral health examiners (dentists) by the professional academy, and "Data management" by the KCDC. After completion of the three-step data check, the indicators of dental caries, periodontal disease, and oral health behavior were published in the National Health Statistics. Conclusions: To achieve the goals of oral health indicators, we will continue to monitor so that we can use it as basic data for oral policies and carry out various linkage analyses related to oral diseases.

• Journal of Korean society of Dental Hygiene
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• v.10 no.2
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• pp.335-344
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• 2010

Objectives : Targeting Korean adults, the food pattern are grasped. And, its correlation with oral disease is analyzed. In order to offer basic data to developing the nutritional policy and nutritional program for the future prevention from oral disease, a research was conducted by utilizing the Korean National Health and Nutrition Examination Survey 2005(the 3rd term). Methods : The subjects in this study were 6,526 adults in more than fully 19 years among 9,047 persons who participated in the food intake survey out of those who completed the health interview survey. The statistical analysis was analyzed by using SPSS 12.0 program. Results : 1. As a result of Group Analyzing was indicated to dangerous-type food pattern and protection-type food pattern. 2. As a result of analyzing the answers for having dental caries in the annually personal recognition was indicated to be high in the dangerous-type food pattern, and had not the statistically significant difference. 3. As a result of analyzing the answers for having periodontal disease in the annually personal recognition was indicated to be high in the dangerous-type food pattern, and had the statistically significant difference(p<0.05). 4. As a result of analyzing the food pattern factors that have influence upon both major oral illnesses in the annually personal recognition, the person, who has the dangerous-type food pattern, had high risk level of the periodontal disease in the annually personal recognition. Conclusions : In the above results, as a result of surveying and analyzing importance of the food pattern in the incidence of both major oral illnesses, it is considered that there will be necessity of continuing to research into developing the nutritional policy and nutritional program in order to prevent oral illness in the future.

• Journal of Periodontal and Implant Science
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• v.44 no.1
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• pp.25-32
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• 2014

Purpose: Periodontitis is an infectious disease caused predominantly by gram-negative anerobes. The host inflammatory response to these bacteria causes alveolar bone loss that is characterized as periodontitis. Omega-3 fatty acids (${\omega}$-3 FAs) have anti-inflammatory properties, thus have been used to treat some chronic inflammatory diseases such as cardiovascular disease and rheumatoid arthritis. We aimed to evaluate the effect of dietary supplementation with ${\omega}$-3 FAs as a host modulating agent in patients with chronic periodontitis. Methods: Sixty otherwise healthy subjects with moderate and severe chronic periodontitis were enrolled in our randomised, double-blind, placebo-controlled trial. The control group (CG, n=30) was treated with scaling and root planing (SRP) and given a placebo; the treatment group (TG, n=30) was treated with SRP and dietary supplementation of ${\omega}$-3 FAs (one 300 mg tablet daily for 12 weeks). Periodontal clinical parameters and serum C-reactive protein (CRP) levels were evaluated in all patients at baseline, a 6-week and 12-week period after treatment. Results: A significant reduction in the gingival index, sulcus bleeding index, pocket depth, and clinical attachment level was found in the TG compared to the CG at a 12-week period. However, no statistically significant changes in serum CRP levels were found. Conclusions: Our findings suggest that ${\omega}$-3 FAs can successfully reduce gingival inflammation, pocket depth, and attachment level gain. Dietary supplementation with ${\omega}$-3 FAs may have potential benefits as a host modulatory agent in the prevention and/or C management of chronic periodontitis.

• Journal of dental hygiene science
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• v.13 no.2
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• pp.142-150
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• 2013

The aim of this study was to analyze the factors related to self-reported halitosis. This study performed a questionnaire survey, targeting at 450 adults who lived in Seoul and Gyeonggi area. Main results of this study were as followings. Relationships between socio-demographic characteristics and halitosis showed no significant difference. Relationships between subjective oral health and halitosis, the groups that were treated dental prosthesis, aware of periodontal disease and dry mouth symptoms reported more halitosis (p<0.05). The group that brushed teeth less than twice a day, did not brush teeth after having a snack, and had frequent sweet treat reported more halitosis (p<0.05). The group that more experienced limitation, discomfort, discomfort reported more halitosis (p<0.05). Based on the results derived as above, the self-reported halitosis was shown to be related to periodontal disease, dry mouth, oral hygiene care and quality of life. Therefore, it is considered that preventing periodontal disease and oral dryness as well as reinforcing the oral hygiene care will contribute to prevention of halitosis and enhancement of quality of life.

• International Journal of Oral Biology
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• v.40 no.2
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• pp.79-83
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• 2015

The purpose of the study was to investigate the antimicrobial activity of the methanol extract of Coptidis rhizome against the type strains of cariogenic bacteria, Streptococcus mutans and Streptococcus sobrinus, and the periodontopathogens, Porphyromonas gingivalis, Prevotella intermedia, Treponema denticola and Aggregatibacter actinomycetemcomitans. The antimicrobial activities of the crude extract and the methanol extract fractions of Coptidis rhizome separated by silica gel chromatography were evaluated by determining the minimal bactericidal concentration (MBC) values, using the microdilution method. The cell viability test of the extracts of Coptidis rhizome on the KB cells was also studied by methyl thiazolyl tetrazolium (MTT) assay. Our results showed that the 11th fraction (F11) of the methanol extract had the greatest antimicrobial activity against the tested bacteria, with no associated cytotoxicity on the KB cells, upto a concentration of $50{\mu}g/ml$. These results suggest that the silica gel chromatography fraction F11 of the methanol extract of Coptidis rhizome, could be useful in the development of oral hygiene products as an antimicrobial agent for the prevention of dental caries and periodontal diseases.

• Journal of Oral Medicine and Pain
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• v.21 no.1
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• pp.133-140
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• 1996

Saliva have many important functions in the maintenance of oral health. Saliva contains protective components, antibacterial enzymes, and other rubricating glycoprotein elements. When the salivary flow decreases of the salivary composition changes, a normally healthy mouth can become susceptible to caries, periodontal disease, and mucositis, and other diseases. Salivary peroxidase system acts as an antimicrobial factor in the oral cavity, having a role in the prevention of dental plaque accumulation, dental caries and gingivitis. Recently, this enzyme system has been introduced by many researchers in the form of toothpaste, mouthwash or moisturizing gel for use in patients with various disease states . The author prescribed the peroxidase system containing gel (Oralbalance) to the 18 Burning Mouth Syndrome (BMS) patients for 1 week and investigated the changes of the subjective symptoms, $HOSCN/OSCN^-$ levels of unstimulated whole saliva, and the salivary flow rates. The obtained results were as follows : 1. The patients reported decrease in all symptoms of BMS after the use of peroxidase system containing gel, particulary, a significantly higher decreases of dry mouth and burning symptoms. 2. Decreased $HOSCN/OSCN^-$ levels of unstimulated whole saliva were detected in the patients with BMS after the use of perosidase system containing gel for 1 week. 3. There was no difference between the flow rates of unstimulated whole saliva before and after uses of peroxidase system containing gel for 1 week.

• Journal of Korean society of Dental Hygiene
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• v.14 no.4
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• pp.511-518
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• 2014

Objectives : The purpose of this study is to investigate the correlation factors to oral health-related quality of life in Chinese students studyng in Korea. Methods : A self-reported questionnaire was filled out by 231 students from November, 2012 to January, 2013. Data were analyzed by t-test, one way ANOVA, and Duncan post-hoc test using SPSS version 19.0. Results : Male students and short period staying students tended to have a higher quality of life. Smokers and large city dwellers tended to have a low oral health-related quality of life(p<0.05). The oral health-related quality of life in Chinese students in Korea was closely related to necessity of dental treatment and past experience of dental treatment services(p<0.05). Conclusions : To improve the oral health-related quality of life in foreign students, it is necessary to provide the early prevention of dental caries and periodontal diseases through the systematic and professional dental health care delivery program for the foreign students studying in Korea.

• Journal of Korean society of Dental Hygiene
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• v.12 no.5
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• pp.1059-1069
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• 2012

Objectives : The purpose of this study was to examine the knowledge of orthodontic patients about oral health knowledge and their actual oral hygiene care, which affected the oral hygiene of orthodontic patients. It's specifically meant to provide information on the prevention of the possible side effects of orthodontic treatment and the promotion of the oral health of orthodontic patients. Methods : This study were 227 orthodontic patients of dental clinics specialized in orthodontics. The collected data were analyzed by the statistical package SPSS WIN 18.0. Results : 1.As for Oral health knowledge, they had the best knowledge about smoking and dental checkup among the subfactors of oral health knowledge. 2. As to actual oral hygiene care, what they did best was doing toothbrushing before sleeping and what they did worst was avoiding eating food injurious to teeth. 3. They scored highest in the right toothbrushing(3.85), the use of oral hygiene supplies(3.62), the prevention of periodontal diseases(3.13) in the subfactors of actual oral hygiene care. They scored lowest in dental checkup and diet(2.99). 4. There were significant differences among the patients in oral health knowledge according to age(F=2.95, p<.05). Those who received another treatment during orthodontic treatment had a better oral health knowledge than the others who didn't, and the gap between the two was statistically significant(t=2.26, p<.05). 5. There were differences among the patients in actual health hygiene care according to gender(t=2.71, p<.01), age(F=4.40, p<.01), educational experiences about oral hygiene care(t=3.06, p<.01) and experience of receiving another treatment during orthodontic treatment(t=2.56, p<.05). 6. There was a positive correlation between oral health knowledge and oral hygiene care(r=.261, p<.001). Conclusions :The above-mentioned findings suggest that more education of diet and toothbrushing should be provided for orthodontic patients to improve their oral health care.

• Journal of The Korean Society of Integrative Medicine
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• v.10 no.4
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• pp.103-111
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• 2022

Purpose : In recent years, essential oils have been produced using natural extracts for various uses. Their functionality is currently being tested not only for cosmetics and perfumes but also for other categories of products. Therefore, this study verified their antibacterial effects on S. mutans, P. gingivalis, and L. gasseri which are the representative strains that cause oral diseases. Methods : Eighteen types of natural essential oils were made at a concentration of 50 % (v/v) using Tween 20, and their antibacterial effects were verified by applying S. mutans, P. gingivalis, and L. gasseri. The antibacterial effects were measured with the disc diffusion method. All the experiments were repeated three times, and the mean value of three measurement values for each variable was used for data analysis. A one-way analysis of variance was conducted using these mean values. Results : Of the eighteen types of essential oils tested, sixteen types showed antibacterial effects on S. mutans, and sixteen and fifteen types exhibited antibacterial effects on P. gingivalis and L. gasseri respectively. The types of essential oils with high-level antibacterial activities were geranium, may chang, and bergamot for S. mutans, lemongrass, bergamot, and eucalyptus for P. gingivalis, and lemongrass, machan, and geranium for L. gasseri in order of antibacterial effect. This result was statistically significant (p<.001). In addition, in the case of mandarin oil, it was found that there was no antibacterial activity in all three strains. Conclusion : This study proved the antibacterial activities of essential oils, which are used for various purposes in daily life, against dental caries and periodontal diseases. The study results will likely be applied to different prevention programs for oral health and broadly used to develop products such as oral care items and dentifrices.