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Analysis of Tranditional Chinese Medicine for Otitis Media with Effusion in Chinese Journals (삼출성 중이염에 대한 중의학 임상 논문 분석)

  • Kim, Su-Jin;Kim, Yeon-Soo;Jee, Seon-Young;Hwangbo, Min
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.33 no.3
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    • pp.69-85
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    • 2020
  • Objectives : The purpose of this study is to investigate the trend of Tranditional Chinese Medicine for Otitis Media with Effusion(OME) in Chinese journals. Methods : Chinese National Knowledge Infrastructure(CNKI) and Wanfang med online were used to search Chinese studies which were published from January, 2010 to April, 2020. Results : Among Chinese studies, Exterior-releasing medicinal(解表藥) and Heat-clearing medicinal(淸熱藥) were the most frequently used. The herbs which used the most frequently are Bupleuri Radix(柴胡), Acori Graminei Rhizoma(石菖蒲). All of studies have reported that Tranditional Chinese Medicine is effective for Otitis Media with Effusion. Conclusions : In analysis of selected studies, Tranditional Chinese Medicine is more effective than Western Medicine Treatments. Recurrence rates and side effects of OME can be reduced by cotreatment of Tranditional Chinese Medicine and Western Medicine Treatments.

Review of International Programs of Chinese Medicine University in China (중국 중의약대학의 외국인 연수프로그램 현황에 대한 고찰연구)

  • Lyu, YeeRan;Lee, Ji-Young;Son, Chang-Gue
    • The Journal of Korean Medicine
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    • v.35 no.3
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    • pp.125-134
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    • 2014
  • Objectives: This study aimed to survey and report on the international programs for Chinese Medicine in China. Methods: Online research was conducted based on a survey of official websites of 25 universities of Chinese medicine. In certain situations, we used e-mail or phone calls to get more detailed information. Results: Among 25 universities of Chinese medicine, 22 operate international programs for Chinese medicine. The main contents of the programs are acupuncture, moxibustion, tuina, Chinese materia medica, cosmetology or qigong, and an average 400 foreign students finish each program yearly. China has maintained the lead in international education of traditional Oriental medicine, and has already established a systematic and remarkable infrastructure for globalization of Chinese medicine. Conclusions: This study can inform the development of strategy in the process of raising the competitiveness of Korean medicine in the world market.

Biosynthesis of rare 20(R)-protopanaxadiol/protopanaxatriol type ginsenosides through Escherichia coli engineered with uridine diphosphate glycosyltransferase genes

  • Yu, Lu;Chen, Yuan;Shi, Jie;Wang, Rufeng;Yang, Yingbo;Yang, Li;Zhao, Shujuan;Wang, Zhengtao
    • Journal of Ginseng Research
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    • v.43 no.1
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    • pp.116-124
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    • 2019
  • Background: Ginsenosides are known as the principal pharmacological active constituents in Panax medicinal plants such as Asian ginseng, American ginseng, and Notoginseng. Some ginsenosides, especially the 20(R) isomers, are found in trace amounts in natural sources and are difficult to chemically synthesize. The present study provides an approach to produce such trace ginsenosides applying biotransformation through Escherichia coli modified with relevant genes. Methods: Seven uridine diphosphate glycosyltransferase (UGT) genes originating from Panax notoginseng, Medicago sativa, and Bacillus subtilis were synthesized or cloned and constructed into pETM6, an ePathBrick vector, which were then introduced into E. coli BL21star (DE3) separately. 20(R)-Protopanaxadiol (PPD), 20(R)-protopanaxatriol (PPT), and 20(R)-type ginsenosides were used as substrates for biotransformation with recombinant E. coli modified with those UGT genes. Results: E. coli engineered with $GT95^{syn}$ selectively transfers a glucose moiety to the C20 hydroxyl of 20(R)-PPD and 20(R)-PPT to produce 20(R)-CK and 20(R)-F1, respectively. GTK1- and GTC1-modified E. coli glycosylated the C3-OH of 20(R)-PPD to form 20(R)-Rh2. Moreover, E. coli containing $p2GT95^{syn}K1$, a recreated two-step glycosylation pathway via the ePathBrich, implemented the successive glycosylation at C20-OH and C3-OH of 20(R)-PPD and yielded 20(R)-F2 in the biotransformation broth. Conclusion: This study demonstrates that rare 20(R)-ginsenosides can be produced through E. coli engineered with UTG genes.

A Comparative Study of the Chinese Characters education in Korea and China (한·중 한자교육 비교)

  • Yu, Hyuna
    • Cross-Cultural Studies
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    • v.27
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    • pp.415-434
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    • 2012
  • The Hanja used in Korean are traditional Chinese characters, but what Chinese people use now is simplified characters. So, there are differences in pronunciation and meaning between the characters used by Korean and Chinese. More than 70% of the Korean language vocabulary derived from or were influenced by hanja. For the inheritance and development of traditional culture,and for the communication among countries of the Chinese characters cultural circle in Northeast Asia, should we build up an authentic Chinese education system. But the government hasn't pay much attention to this work, and the government's policy can't implement the efficient education. Consequently, in these days, there are more and more Korean people who are functionally illiterate in Chinese. Recently, proficiency tests of Chinese characters are expected to promote the development of Chinese education. But, most Koreans' motives for Chinese study are usually to pass the college entrance exam or to compete for jobs. However, after passing the test, the motive for studying gradually fade away. It is the basic problem faced by Korean Chinese character education. Since the 1950s, various character education methods have been studied in China, the research results were appliedin their textbooks and other materials. Therefore, a well-organized and efficient learning-by-step education system was built up. At present, China's literacy education in the textbooks utilizes a range of methods including revisional centralized and distributed. Unfortunately, there is still one shortcoming worthy of concerns: how to solve the problems due to the simplification of traditional Chinese characters? Is it possible to revive traditional Chinese characters? Before adopting the results of research on China's literacy education and applying them to our character education, we should consider our specific situation carefully. Adopting the research results with cautious review and objective criticism should have a positive impact on Korean Chinese character education.

Internet Addiction and Life Satisfaction of Chinese Students in Korea (중국 유학생의 유학생활 만족도와 인터넷 중독에 관한 연구)

  • Fu, Wen Wen;Kim, Min Jeong
    • Korean Journal of Human Ecology
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    • v.23 no.3
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    • pp.557-569
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    • 2014
  • As the number of Chinese students in Korea has significantly increased, the problems of students' life and academic achievement has appeared obviously. Utilizing an analysis on the relationship between the life satisfaction of Chinese students in Korea and the degree of internet addiction, the purposes of this research are to improve the quality of Chinese students' life and to contribute to the growth of Chinese students in Korea. A questionnaire-type survey was conducted on 350 Chinese college students in Daegu. The results of this study are as follows: First, the used time on internet games, chat and on-line TV differs from gender, the duration of internet games and their academic performance. Second, there are significant differences by gender, Korean ability, and academic performance in the life satisfaction of Chinese students in Korea. Third, Chinese college students in Korea are more addicted in the internet than Korean or Chinese college students at their own country. Fourth, the longer playing online game, the longer watching online TV, the less communicating with the Koreans, and the less satisfying with non -study related activities, the more Chinese college students of studying in Korea are addicted in the internet.

The Recognition and Pedagogy of Chinese Tones (중국어 성조의 인지와 교육)

  • Shim So Hee
    • MALSORI
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    • no.40
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    • pp.65-78
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    • 2000
  • Korean learners of Chinese have diniculties in pronouncing Chinese tones which distinguish the meaning of words, because there are not such tones in Korean language. It makes Koreans hard to acquire Chinese. In this paper, I present the followings: First, I examine the characteristics of the tones pronounced by Korean speakers, exploiting the method of modern experimental phonetics. Second, I present the pedagogy of Chinese tones, considering the typical errors shown by the experiments on Korean speakers. The Pedagogy Presented in this Paper, which is based on the results of experiments, is not perfect. However, I expect this paper to serve as instrumental tools to help Korean speakers to improve their command of Chinese.

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A study on the teaching of the Chinese language in the Chosun Dynasty in the context of international exchanges (국제 교류 시각에서 본 조선시대 한문교육 분석)

  • Wang, jinling
    • Journal of the International Relations & Interdisciplinary Education
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    • v.2 no.1
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    • pp.43-55
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    • 2022
  • Through literary research, this study aims to study chinese characters in the Chosun Dynasty from the perspective of international exchange. While sorting out the historical materials, it investigates the implementation organ, educational content and main characteristics of Chinese education in the Chosun Dynasty, its influence on the Korean peninsula at that time and Its enlightenment to today's Chinese international education. The results show that the Chinese language education institutions in the Chosun Dynasty mainly played the role of Chinese language education in the Si service academy and the Sheng Wen Academy. The contents of Chinese language education mainly include the development of oral Chinese teaching materials, the publication of rhymes and other reference books, the compilation of dictionaries and the training of Chinese translators. Through the in-depth study of Chinese rhymes, the Korean Peninsula created its own Korean national character in 1443, getting rid of the will of Chinese characters. The invention of Korean language has greatly encouraged the political, economic and cultural development of the Korean peninsula. In addition, the Chinese language education in the Chosun Dynasty provides a good experience for today's Chinese international education in China.

A comprehensive quality analysis of randomized controlled clinical trials of Asian ginseng and American ginseng based on the CONSORT guideline

  • Chen, Weijie;Li, Xiuzhu;Chen, Zhejie;Hao, Wei;Yao, Peifen;Li, Meng;Liu, Kunmeng;Hu, Hao;Wang, Shengpeng;Wang, Yitao
    • Journal of Ginseng Research
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    • v.46 no.1
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    • pp.71-78
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    • 2022
  • Ginseng is an international herb that has been used for thousands of years. Two species most commonly applied and investigated in the ginseng family are Asian ginseng and American ginseng. The number of randomized controlled clinical trials (RCTs) has conspicuously increased, driven by the rapid development of ginseng. However, the reporting of RCT items of ginseng is deficient because of different trial designs and reporting formats, which is a challenge for researchers who are looking for the data with high quality and reliability. Thus, this study focused on providing an extensive analysis of these two species and examined the quality of the RCTs, based on the Consolidated Standards of Reporting Trials (CONSORT) guideline. Ninety-one RCTs conducted from 1980 to 2019 that were related to Asian ginseng and American ginseng used singly met our inclusion criteria. We found that the reporting quality of the two species has improved during the past 40 years. Publication date and sample size were significantly associated with the reporting quality. Rigorous RCTs designed for the species of ginseng are warranted, which can shed light on product research and development of ginseng in the future.

Stem-leaf saponins from Panax notoginseng counteract aberrant autophagy and apoptosis in hippocampal neurons of mice with cognitive impairment induced by sleep deprivation

  • Cao, Yin;Yang, Yingbo;Wu, Hui;Lu, Yi;Wu, Shuang;Liu, Lulu;Wang, Changhong;Huang, Fei;Shi, Hailian;Zhang, Beibei;Wu, Xiaojun;Wang, Zhengtao
    • Journal of Ginseng Research
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    • v.44 no.3
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    • pp.442-452
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    • 2020
  • Backgroud: Sleep deprivation (SD) impairs learning and memory by inhibiting hippocampal functioning at molecular and cellular levels. Abnormal autophagy and apoptosis are closely associated with neurodegeneration in the central nervous system. This study is aimed to explore the alleviative effect and the underlying molecular mechanism of stem-leaf saponins of Panax notoginseng (SLSP) on the abnormal neuronal autophagy and apoptosis in hippocampus of mice with impaired learning and memory induced by SD. Methods: Mouse spatial learning and memory were assessed by Morris water maze test. Neuronal morphological changes were observed by Nissl staining. Autophagosome formation was examined by transmission electron microscopy, immunofluorescent staining, acridine orange staining, and transient transfection of the tf-LC3 plasmid. Apoptotic event was analyzed by flow cytometry after PI/annexin V staining. The expression or activation of autophagy and apoptosis-related proteins were detected by Western blotting assay. Results: SLSP was shown to improve the spatial learning and memory of mice after SD for 48 h, accomanied with restrained excessive autophage and apoptosis, whereas enhanced activation of phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway in hippocampal neurons. Meanwhile, it improved the aberrant autophagy and apoptosis induced by rapamycin and re-activated phosphoinositide 3-kinase/Akt/mammalian target of rapamycin signaling transduction in HT-22 cells, a hippocampal neuronal cell line. Conclusion: SLSP could alleviate cognitive impairment induced by SD, which was achieved probably through suppressing the abnormal autophagy and apoptosis of hippocampal neurons. The findings may contribute to the clinical application of SLSP in the prevention or therapy of neurological disorders associated with SD.

A Study on Korean-chinese Elementary School Facility In China Yanji (중국 연길시 조선족 소학교시설 기초연구)

  • Kim, Jong-Young
    • Journal of the Korean Institute of Educational Facilities
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    • v.18 no.3
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    • pp.13-21
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    • 2011
  • Yanji city in China is a city most populated with Korean-chinese. This study is to examine architectural planning characteristics for Korean-chinese Elementary schools in Yanji city. Currently, this city includes nine Korean-chinese schools. This research has been processed with regards to three broad aspects. Firstly changing processes of school systems, secondly local distributions and networks of school facilities, and thirdly site plans, floor plans and elevations of school buildings were analyzed and examined for finding their characteristics. For this study, seven Han-chinese Elementary schools were also analyzed. The study result are as following: 1. Korean-chinese schools have followed national education policies and also maintained Korean-chinese native education methods. The schools have undergone merger and separation with Han-chinese Elementary schools. Three Korean-chinese Elementary schools in Japan Colonials, two schools in the period of the Republic of China foundation and its growing, and four schools in 1980s were founded. 2. Yanji city administers the networks of Korean-chinese school districts and Han-chinese districts separately. All school districts apply to lkm standard as attending distance. The networks are adjusted as per population change. 3. The characteristics of buildings' site plans, floor plans and elevations are simple. Layouts of the schools are - type or -type centered playground. Building plans show one side corridor type and 5 stories mostly. Elevations stress central parts. Various forms such as finger types do not appear in mass planning since the school curriculum and extracurricular activities are not seemingly active. Han-chinese Elementary schools have similar conditions.

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