• Therapeutic Science for Rehabilitation
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• v.7 no.2
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• pp.41-50
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• 2018

Objective: This study was conducted to investigate the correlation of cognitive function and fall-risk behavioral factors. Methods: The elderly over than 65 year-old with and without cognitive impairment were recruited in four different regional areas. Total 43 data of K-MoCA and FaB were collected. Pearson correlation of total scores of K-MoCA and FaB was analyzed using SPSS 22. Correlation between total score of K-MoCA and each item of FaB which describes the fall-risk behaviors was analyzed as well. Results: The cognitive function was statistically positive correlated with the fall-related behaviors in pearson correlation analysis (p<.01). Nine items of total 30 items of FaB was significantly correlated with total score of K-MoCA. Conclusion: Fall-risk behaviors were decreased as the cognitive level was improved. If the cognitive function was vulnerable, the insight to fall-risk behaviors deficits and various fall-related behavioral factors exits. The high fall-risk behaviors were correlated with cognitive function, so that the cognitive level should be considered in fall prevention intervention in Occupational Therapy.

• The Journal of the Korea Contents Association
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• v.15 no.3
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• pp.184-191
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• 2015

Prostate ultrasound is used to diagnose prostate cancer, BPH, prostatitis and biopsy of prostate cancer to determine the size of prostate. BPH is one of the common disease in elderly men. Prostate is divided into 4 blocks, peripheral zone, central zone, transition zone, anterior fibromuscular stroma. BPH is histologically transition zone urethra accompanying excessive nodular hyperplasia causes a lower urinary tract symptoms(LUTS) caused by urethral closure as causing the hyperplastic nodule characterized finding progressive ambient. Therefore, in this study normal transition zone image for hyperplasia prostate and normal transition zone image is analyzed quantitatively using a computer algorithm. We applied texture features of GLCM to set normal tissue 60 cases and BPH tissue 60cases setting analysis area $50{\times}50pixels$ which was analyzed by comparing the six parameters for each partial image. Consequently, Disease recognition detection efficiency of Autocorrelation, Cluster prominence, entropy, Sum average, parameter were high as 92~98%.This could be confirmed by quantitative image analysis to nodular hyperplasia change transition zone of the prostate. This is expected secondary means to diagnose BPH and the data base will be considered in various prostate examination.

• Korean Journal of Biological Psychiatry
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• v.22 no.4
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• pp.155-162
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• 2015

Objectives Second-generation antipsychotics (SGAs) are frequently used in the treatment of bipolar disorder. However, there is still no consensus on their risk of tardive movement syndromes especially for first-generation antipsychotics (FGAs)-naïve patients. This study aimed to investigate the prevalence and associated factors of SGAs-related tardive dyskinesia and tardive dystonia in patients with bipolar disorder, in a naturalistic out-patient clinical setting. Methods The authors assessed 78 non-elderly patients with bipolar (n = 71) or schizoaffective disorder (n = 7) who received SGAs with a combined use of mood stabilizers for more than three months without previous exposure to FGAs. Multiple direct assessments were performed and hospital records longer than one recent year describing any observed tardive movement symptoms were also reviewed. Results The prevalence rates of tardive dyskinesia and tardive dystonia were 7.7% and 6.4%, respectively. These patients were being treated with ziprasidone, risperidone, olanzapine, quetiapine, or paliperidone at the time of the onset of the movement symptoms. Tardive dyskinesia was mostly observed in the orolingual area, and tardive dystonia was most frequently detected in oromandibular area. A past history of acute dystonia was significantly associated with presence of both tardive movement syndromes. Conclusions Our findings suggest that SGAs-related tardive movement syndromes occur in a substantial portion of bipolar disorder patients. Acute dystonia, a reported risk factor of tardive movement syndromes in the era of FGAs is confirmed as a risk factor of both tardive dyskinesia and tardive dystonia that were induced-by SGAs.

• Journal of Life Science
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• v.30 no.2
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• pp.202-210
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• 2020

As the elderly population increases, it is becoming important to prevent and treat muscle loss caused by aging or disease. Steroidal androgen in the protein assimilation steroid (AAS) system is mainly used to induce muscle improvement, but it is well known that long-term or excessive doses of AAS result in various side effects, although they are prescribed for various muscle and weight loss treatments. Research is therefore underway to explore natural substances that promote muscle renewal with relatively few side effects. However, despite many studies on the improvement of skeletal muscle and the reduction of muscle disease using natural products, there is still a lack of significant clinical results and mechanism studies. The promotion of muscle regeneration through treatment with natural substances typically involves three mechanisms: positive control of the muscle modulating factor (MRF), activation of the protein synthesis mechanism, and inhibition of the protein breakdown mechanism. A study of plant extracts that are known to have muscle neoplasmic stimulation effects, such as black ginseng, plum, and nutmeg, as well as single substances derived from natural products, such as creatine, catechin, and several fatty acids, is therefore described. We also summarize the mechanisms that have been identified so far through which each of these extracts or single materials facilitates muscle regeneration and the signaling pathways that they mediate.

• Journal of Korean Society for Geospatial Information Science
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• v.20 no.4
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• pp.37-44
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• 2012

There are approximately 25,724 shelters to which people can be quickly evacuated for safety in case of emergency across the nation, and Seoul has about 3,870 shelters. Those nationwide shelters are located at a point within a five-minute radius for quick evacuation. Seoul's shelter capacity can hold 285% of its population. The problem is, however, that there is no knowing how many shelters are reachable within five minutes when considering walking speed according to individual differences in age, height, health state, and physical condition. In addition, available service areas become different according to the spatial allocation and distribution of shelters with possible vulnerable points. This study thus defined the pedestrian walking speed at 1m/s, 1.3m/s, and 2m/s by reviewing previous studies and conducted network analysis of the Location Allocation Model with the designated shelters and road networks in Seoul. The results identified the shelter service and vulnerable areas in each administrative district of Seoul according to walking speeds. It was analyzed that the vulnerable areas in which the elderly could not reach a shelter were more than twice as big as those of adult men and women with a fast walking speed.

• Journal of Digital Convergence
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• v.15 no.9
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• pp.15-21
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• 2017

Our current study aimed to verify the mediating effect of growth mindset and grit in the relationship between human rights victimization and self-esteem. The survey was conducted on 233 college students. Reliability analysis, correlation analysis, and Macro Process were performed, and bootstrap method was used to verify the mediating effect of growth mindset and grit. The results were as follows. First, human right victimization were significantly and negatively correlated with self-esteem, growth mindset, and grit while self-esteem were significantly and positively correlated with growth mindset, and grit. Second, as a result of path analysis, the human rights victimization had a significant negative impact on self-esteem, growth mindset and grit. On the other hand, growth mindset and grit had a significant positive effect on self-esteem. Third, growth mindset and grit had a mediating effect in the relationship between human right victimization and self-esteem. This implied that self-esteem of college students can be increased by increasing their growth mindset and grit. Future research is needed to clarify the role of human rights research and growth mindset and self - esteem in college students.

• The Journal of the Korea Contents Association
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• v.16 no.12
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• pp.667-676
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• 2016

The purpose of study was to determine the differences in organizational culture between social enterprises and commercial enterprises and assess the impact on organizational performance in Korea. Main results are as follows. First, Social enterprises employ a lot of low-imcome women and the elderly worker. Second, rational culture is high in profit businesses, but cultural group is high in social enterprises. In commercial enterprise, productivity and efficiency, planning and goal setting, assessing goals and looking for the evaluation of the performance are important. and in social enterprise, affinity and participation, employees individual development and group morale and cohesion, emphasis on mutual cooperation and trust are important. In addition, both social performance and economic performance, social enterprises are higher than in commercial enterprises. Social enterprises are operating transparently based on workers participation and understanding is expected that economic performance is also highly recognized. Third, social performance is higher development and group culture are higher in commercial enterprises, and development, group and hierarchy culture are higher in social enterprises. Economic performance is higher reasonal culture is lower in commercial enterprises, and group culture is higher in social enterprises. Therefore, the social enterprise workers are recognizing social and economic performance are higher than commercial enterprise workers. In short, social enterprises is making discriminatory organizational culture, and this is contributing to achieving organizational performance.

• Korea journal of population studies
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• v.30 no.2
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• pp.45-69
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• 2007

This study analyzes differences of self-rated health status between Korea and three European countries. Self-rated health status is highly correlated with objective health status such as chronic diseases and ADL(Activities of Daily Living)/IADL(Instrumental Activities of Daily Living), but it is also influenced by individual attitude or belief about health. Therefore, differences of self-rated health status among countries are determined by the combination of (1) differences of objective health status and (2) socio-cultural characteristics affecting individuals' attitude and belief. Using 'Korean Longitudinal Study of Ageing(KLoSA 2006)' and 'Survey of Health, Ageing, and Retirement in Europe (SHARE 2004)', we found that Korean older people are more likely to feel negatively on their health status than their European counterpart. The findings are explained in two different ways. First, how strongly the objective health status affects on the subjective health status varies among countries. Korean older people with chronic diseases are more likely to evaluate their health status negatively because of the diseases than their European counterparts do. Second, after controlling the effects of the objective health condition, the subjective health status of Korean older people is still lower than that of the European elderly.

• Korean Journal of Clinical Pharmacy
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• v.23 no.1
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• pp.42-48
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• 2013

Background: Patients diagnosed with cancer tend to have multiple risk factors for drug related problems such as old age, comorbid conditions, self-medication, additional medications for supportive therapy, and the cancer treatment itself. Objective: The aim of this study was to investigate notable polypharmacy and related problems in oncology patients during hospitalization or following clinic visit. Method: The electronic medical records of patients who were discharged from oncology division at Seoul National University Hospital (SNUH) from June $1^{st}$ to June $30^{th}$, 2011 were retrospectively reviewed. Results: A total of 334 discharged patients were included in this study. Among them, 221 patients had pre-admission medications. Forty percent of the patients, including 60.3% of elderly patients (over 65 years of age) were prescribed more than 5 kinds of medications. Twenty percent of the patients were prescribed to take medications more than 7 times a day. Medication duplications were observed in 2.4% of patients. In 10.5% of the reviewed patients, 47 cases of potential drug-drug interaction including 3 cases of contraindication and 17 cases of major clinical implication according to Micromedex were detected. Medication changes were made in 88% of patients during hospitalization and in 94.7% of patients at their first visit after discharge. Antidiarrheal agent (loperamide) was prescribed along with laxatives in 18.5% of the prescriptions and inadequate instructions on how to take it were observed in 63% of the prescriptions. Conclusion: This study identified the prevalence of polypharmacy and related problems in cancer patients, which presents the need for an active role of pharmacists in pharmaceutical care in oncology wards.

• Korean Journal of Construction Engineering and Management
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• v.19 no.3
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• pp.11-22
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• 2018

Existing efforts to reduce total egress time actually focused on reducing travel time. However, consideration to reduce perception time or response time was insufficient although the ratio of travel time is one-third of total egress time and situations which the safety cannot be ensured by only reducing travel time were aroused. Therefore, the concept of disaster information, which could reduce both perception time and response time got attention To analyze the effect of disaster information on occupant behaviour, this study identified a relationship between 10 major disaster information and 3 occupant behaviour factors in terms of reducing egress time. By referring the relationship, this study conducted an virtual egress experiment with survey on 4 cases, the elderly, intellectual disabled, hearing disabled and visual disabled, to identify disaster information which reduce total egress time effectively. Finally, by analyzing the experiment result, this study proposed the process of disaster information effect on occupant behaviour as complementing insufficient occupant behaviour to ensure the minimum level of safety and maximizing relatively high occupant behaviour to ensure enough level of safety. The results are expected to account for relationship between disaster information and occupant behaviour with more explanatory power in terms of egress time. With further studies of disaster information and group behaviour, these series of studies could provide basic references for disaster information and occupant behaviour.