• The Korean Journal of Pain
• /
• v.19 no.2
• /
• pp.285-287
• /
• 2006

Hundreds of drugs have been implicated as the causes of antibody-mediated thrombocytopenia. Naproxen is a commonly used nonsteroidal anti-inflammatory drug, and it is generally considered to be safe with few hematological side effects such as thrombocytopenia. In this case, severe thrombocytopenia associated with petechia and epistaxis appeared after initiation of naproxen therapy in the 59-year-old man. We report here on a case of severe thrombocytopenia that was recognized at 10 days after the use of naproxen, and the patient rapidly recovered to a normal platelet count without bleeding symptoms or any complications, although immunoglobulin or steroid was not used.

• Journal of the Korean Society of Tobacco Science
• /
• v.17 no.1
• /
• pp.62-67
• /
• 1995

Deliveries of tar, nicotine and carbon monoxide in mainstream smoke decreased with increment of exogenous potassium content of tobacco. Potassium malate was more effective than potassium nitrate, potassium carbonate, potassium citrate and potassium oxalate for the reduction of carbon monoxide, but potassium nitrate was more effective than potassium palate, potassium carbonat, potassium citrate and potassium oxalate for the reduction of carbon in the case of nicotine. Puff count and burning rate were slightly changed with added potassium salts.

• Journal of Korean Society for Quality Management
• /
• v.33 no.1
• /
• pp.83-87
• /
• 2005

For the count response we normally consider Poisson regression model. However, the conventional fitting algorithm for Poisson regression model is not reliable at all when the response variable is measured with sizable contamination. In this study, we propose an alternative fitting algorithm that is resistant to outlying values in response and report a case study in semiconductor industry.

• The Journal of the Korea Contents Association
• /
• v.9 no.4
• /
• pp.275-285
• /
• 2009

During an 8 month period from January to August 2007, complete blood count (CBC) samples were taken from various wards and from the outpatient department at Samsung Medical Center. In order to determine whether or not the total white blood cells were over counted, results were obtained from both the 4Diff/channel and the white blood cell channel from the automated blood analysis equipment from S company for comparison. Among patients who were on long term treatments, the number of cases determined to be over counted by comparing the WBC counts during this 8 month period was 25. Clinical chemistry tests were also conducted on the same day on the 25 samples taken. 68% of the patients showed to exceed normal range of aspartate transaminase (AST) and alanine aminotransferase (ALT) indicating abnormal liver function, and the total bilirubin range were also in excess in 60% of the total samples taken. Further clinical information which was obtained from the patients showed 98% of the patients were administered with cefepime which is the 4th generation cephalosporin at the time when the WEC were over counted. It is assumed that a multiple of factors investigated caused the over count of the WEC rather than a single factor.

• Journal of the Korean Society for Precision Engineering
• /
• v.12 no.9
• /
• pp.74-85
• /
• 1995

The purpose of this paper is to evaluate the grade of WA vitrified and resinoid bond grinding wheels by the sue of AE measuring system. When the manufactured 48 kinds of specimens were scratched by the method of OKOSHI'S grade test, the relationship between the amount of bit scratch depth of grinding wheel specimens and the character- istics of AE signals, and the relationship of AE counts and grade were considered as fololws; (1) The higher the grades are AE cumlulative event counts N and AE event count rate n, the smaller the values tend to be. But A $E_{rms}$is in reverse. (2) In the case of same grade, the smaller the grain size is, the higher the value of AE cumulative event counts N and A $E_{rms}$is results of comparison and observation. The grinding wheel with lower elasticity and with higher percentage of pore detected higher value of AE cumula- tive event counts N than with higher elasticity and lower percentage of pore. But A $E_{rms}$ is in reverse. (3) AE cumulative event counts N and bit scratch depth h have normally one to one correspondence. (4) It can be expected that quantitative evaluations of grade by using AE have been carried out by the wave observation of AE signal in line with the relationship between load speed of bit and AE cumulative event counts N & AE event count rate n.' AE event count rate n.ate n.

• Asian-Australasian Journal of Animal Sciences
• /
• v.24 no.7
• /
• pp.1001-1006
• /
• 2011

To determine the efficiency of copper (Cu) supplementation, a feeding experiment was carried out with 240 day old broiler chicks (vencobb-100). Birds were divided into four dietary treatments: i) C - no additives, ii) $T_1$-75 mg inclusion of Cu/kg diet, iii) $T_2$-150 mg inclusion of Cu/kg diet, iv) $T_3$-250 mg inclusion of Cu/kg diet. The present study was carried out in the Department of Animal Physiology, West Bengal University of Animal and Fishery Sciences, Kolkata, India for a period of 42 days (6 weeks). Growth performance was measured in terms of live weight gain, cumulative feed intake and feed conversion ratio at the end of $21^{st}$ and $42^{nd}$ day of the experiment and the result was found to be encouraging for commercial enterprises when the chickens were fed at 150 mg Cu/kg ($T_2$) of their diet. Excess dietary copper more than 150 mg/kg reduced the haemoglobin (Hb) concentration in blood and resulted in the accumulation of copper in the liver with decreased blood Hb concentration and packed cell volumes (PCV). Copper supplementation increased the total erythrocyte count (TEC) as copper is involved in erythropoiesis. But, from the result it is indicated that the dietary copper concentration could not alter the total leukocyte count (TLC). In case of different leucocytes count (DLC), there were no significant differences observed among the different treated groups. Statistical analysis showed significant (p<0.01) difference in plasma concentration of copper, zinc, ferrous and cholesterol among the different copper treated groups. The result indicates that supplementation of copper is an effective way of improving the production performance and haematological parameters in broiler chicken.

• Journal of Periodontal and Implant Science
• /
• v.28 no.1
• /
• pp.187-191
• /
• 1998

Aplastic anemia is a disease characterized by general lack of bone marrow activity; It may affect not only the red blood cells but also the white blood cells and platelets, resulting in pancytopenia. Spontaneous gingival hemorrhage is present in some cases and it is related to the blood platelet deficiency. This case report presents the periodontal treatment of a patient with aplastic anemia. A 43-year-old female was referred for continuous gingival bleeding after periodontal treatment. Periodontal findings revealed generalized gingival imflammation, oozing of blood from gingival crevice, and it was diagnosed as adult periodontitis. Root planing and extraction of the upper left third molar with poor prognosis were put into operation after elevation of the platelet count with platelet transfusion. The extraction socket was sutured with 3-0 silk. Bleeding continued even after digital compression at the upper right second premolar, second molar, and left canine areas, which presented severe inflammation. Although platelets were transfused repeatedly, platelet count did not stay elevated since survival rate of the transfused platelets were low due to alloimmunization. Thrombin gauze packing was not effective. Bleeding ceased 3 days after treatment with transfusion of donor platelets. 20 days after the treatment, the gingiva was generally healthy except upper right second premolar and lateral incisor areas. The result of periodontal treatment was good, but bleeding control after treatment was troublesome. In the periodontal treatment of patient with aplastic anemia, elevation of the platelet count with platelet transfusion seems to be the best method for hemorrhage control.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.38B no.6
• /
• pp.446-453
• /
• 2013

Clustering schemes have been adopted as an efficient solution to prolong network lifetime and improve network scalability. In such clustering schemes cluster ratio is represented by the rate of the number of cluster heads and the number of total nodes, and affects the performance of clustering schemes. In this paper, we mathematically analyze an optimal clustering ratio in wireless sensor networks. We consider a multi-hop to one-hop transmission case and aim to provide the optimal cluster ratio to minimize the system hop-count and maximize packet reception ratio between nodes. We examine its performance through a set of simulations. The simulation results show that the proposed optimal cluster ratio effectively reduce transmission count and enhance energy efficiency in wireless sensor networks.

• Journal of Yeungnam Medical Science
• /
• v.37 no.4
• /
• pp.332-336
• /
• 2020

Homozygous mutations in NUDT15 R139C are known as the major factor associated with thiopurine-induced early leukopenia, particularly in Asian patients. Therefore, NUDT15 genotyping is currently recommended before thiopurine treatment to identify patients who are NUDT15 poor metabolizers and consider the use of an alternative immunomodulatory therapy. We report a case of a 12-year-old Korean girl with Crohn's disease (CD), in whom thiopurine-induced leukopenia was prevented by initiation of azathioprine (AZA) therapy at a low dose (0.5 mg/kg/day) and early detection of significant hair loss and white blood cell (WBC) count decrease at 17 days from the start of AZA treatment. The WBC count dropped from 8,970/μL to 3,370/μL in 2 weeks, and AZA treatment was stopped because of concerns of potential leukopenia in the near future. Her WBC count recovered to 5,120/μL after 3 weeks. Gene analysis later revealed that she had a homozygous mutation in NUDT15 R139C, resulting in a poor metabolizing activity of NUDT15. In situations when NUDT15 genotyping is unavailable, initiation of AZA therapy at 0.5 mg/kg/day with close observation of hair loss and WBC counts within 2 weeks may be an alternative way to prevent thiopurine-induced early leukopenia in Asian children with CD.

• The Korean Journal of Nuclear Medicine Technology
• /
• v.21 no.1
• /
• pp.29-33
• /
• 2017

Purpose In this study, we evaluated image by applying normalization factor during 30 days to the PET images. Materials and Methods Normalization factor was acquired during 30 days. We compared with 30 normalization factors. We selected 3 clinical case (PNS study). We applied for normalization factor to PET raw data and evaluated SUV and count (kBq/ml) by drawing ROI to liver and lesion. Results There is no significant difference normalization factor. SUV and count are not different for PET image according to normalization factor. Conclusion We can get a lot of information doing the quality assurance such as performance of sinogram and detector. That's why we need to do quality assurance daily.