• Title/Summary/Keyword: testing effect

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Evaluation of Psychosocial Impact and Quality of Life in BRCA Mutation Family (BRCA 돌연변이 가계의 심리상태 및 삶의 질 평가)

  • Han, Sang-Ah;Kim, Sai-Rhee;Kang, Eun-Young;Kim, Jeong-Hyun;Ha, Tae-Hyeon;Yang, Eun-Joo;Lim, Jae-Young;Han, Won-Shik;Noh, Dong-Young;Kim, Sung-Won
    • Journal of Genetic Medicine
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    • v.7 no.1
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    • pp.67-77
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    • 2010
  • Purpose: The aims of this study are to evaluate psychological impact and quality of life according to the cancer diagnosis and mutation status in Korean families with BRCA mutations. Materials and Methods: Seventeen affected carriers (AC), 16 unaffected carriers (UC) and 13 healthy non carriers (NC) from 13 BRCA mutation families were included in the study. Outcomes were compared with regard to depression (Beck Depression Inventory), anxiety (State-Trait Anxiety Inventory, STAI), optimism (Reevaluation of the Life Orientation test, LOT-R), knowledge of hereditary ovarian cancer, and quality of life (QoL) (SF-36v2 Health Survey, physical component score [PCS], mental component score [MCS]) among three groups. Result: Level of depression, optimism, and PCS were similar in AC, UC, and NC. Anxiety score was elevated in all three groups. MCS was significantly low in AC than in UC and NC (P=0.009, P=0.017). Knowledge of hereditary breast and ovarian cancer was high in AC than NC (P=0.001). MCS was significantly related to whether patient was affected by cancer (P=0.043) and has occupation (P=0.008) or not in multivariable analysis. Conclusion: From this cross sectional study, psychological adverse effect was not related to the carrier status of BRCA mutation. Elevated anxiety in BRCA family members was observed but, independent to affection and the type of genetic mutation. AC showed low mental QoL. Further effort to understand psychological impact and QoL of genetic testing in BRCA family members is required for follow-up in clinical aspects.

College-bound Curriculum Developement for Training of Atomic Industry Technician (원자력산업 중견전문인력 양성을 위한 전문대학 교육과정 개발)

  • Lyu, Kwang-Yeul;Kim, Sung-Soo;Ahn, Sung-Min
    • Journal of radiological science and technology
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    • v.28 no.1
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    • pp.33-44
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    • 2005
  • The objective of this study is to supply the good quality of experts the radiation industries in Korea and develop the major subject matter needed in the radiation industries and the curriculum in order to execute it for the variation of fields of employment at the department of radiation in the junior college and the development of the percentage of employment. In addition, this study is to improve the level of radiation experts engaged in the industries in quality, and it is to improve the social recognition of radiation rather negative now because of the development of radiation industry. As for the core results of this research, it was to suggest the detailed choice method curriculum proper to the service fields of radiation industries, but it may be subject to change due to each college's property and the educational objectives. From the result of this research above, it may be summed up as follows. First, as for the detailed curriculum by the service field, this study was to organize two subject matters: 1. the subject matter proper to the field of using the radiation, and 2. the subject matters proper to the safety control field of radiation. Second, as for the detailed curriculum by the pattern of industries, this study was to organize the four subject matters: 1. the subject matter needed in the manufactures, 2. the subject matter needed in the nondestructive testing industries, 3. the subject matter needed in the sales agencies, and 4. the subject matter needed in the laboratories. This study was to suggest the operational model about the curriculum in order to execute these subject matters. It could be executed as two methods below. First, one method is to execute the major systems by the medical field and industrial field in the third course at the department of radiation in the junior college now. Second, the other method is to make them specialize the industrial radiation in the Advanced Course(one year course) after the graduation of junior college. To operate these curricula successively it needs to assume the deeper research and the development of materials about the subject matters related to the nuclear radiation industries hereafter. In addition, it needs to solve the security of finance like the manpower of professor, space for practice, and the educational appliances, etc. needed in the operation of subject matters. Finally, the effect and result from the development or revision of college curriculum did not come out in a short time. It will require considerable time until the undergraduates at the department in the junior college finish a set of curriculum newly developed, and graduate the university, and can get the results while they engage in their works in the industrial sites. Accordingly, all the interested parties have to anticipate the results of this research with the patience in long-standing point of view. Also, this researcher considers it as it is willing to give them the continuous interest and support.

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The influencing effect on E.Q. and personality that both sports activity & speciality aptitude activity in school-childhood can cause (학동기의 스포츠활동과 특기적성활동의 참가가 감성지수 및 성격특성에 미치는 영향)

  • Lee Han-Ki
    • The Journal of Korean Physical Therapy
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    • v.16 no.1
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    • pp.140-156
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    • 2004
  • This study, to find whether a sports activity and a speciality aptitude activity in school-childhood can affect in forming E.Q, has been done in Gyoung-Nam area and Busan wide city with asked 222 of men and women being in their school-childhood and a group of 85 people who had not joined in such activity, using a E.Q testing paper provided by Dae-Gyo Education Corp,. and Seoul National University Educational Research Institute. Following is the results after analyzing the compiled datas. 1. The E.Q. level difference between people who joined, and who not joined in a sports action activity was reported existing, the total E.Q average of those who joined was resulted 212.6, a point 29.6 higher than those not joined of 183.0 ( p< .05). As for the E.Q causing points, it resulted that the points of the joined group is generally up than that of the non-joined group, especially this difference was remarkable in terms of feeling recognition or feeling control, a finding that deserves an attention ( p<.05) 2. Joining periods of sports activity did also have relation to develping E.Q. of school-childhood according to this research, the total E.Q points of a group joined in the activity more than 2 years was 215.5 points, which was 17.4 points higher than those not joined of 186.5 points ( p< .05). Backing again to E.Q causing points in this case, it resulted without exeption of all main causes that those who joined in more than 2 years are generally higher than that of those joined less than 2 years, especially the difference was regarded as big in terms of feeling recognition or feeling control, a finding that deserves an attention ( p<.01). 3. The E.Q. differnce between those joined in a specialty aptitude activity and not joined was studied existing, the total E.Q average points of those joined in a specialty aptitude activity was 207.8, a higher figure by 21.3 points than those not joined group of 186.5 ( p< .05). As for the E.Q causing points, it resulted without exeption of all main causes that those who joined are generally higher than that of those not joined, especially for feeling recognition or feeling control, this difference was more clear, a finding that deserves an attention ( p<.01). 4. It also resulted that E.Q growth depends on the periods to have joined in a speciality aptitude activity, for example, the total E.Q points of those joined in the activity more than 2 years was 217.1, a total more higher by 13.5 points than 203.6 of those not joined ( p< .05). For the E.Q. causing points, it, with the exception of empathy was resulted that those who joined in the speciality aptitude activity more than 2 years are generally higher than those joined less than 2 years, especially the difference is remarkable in terms of feeling recognition or feeling control, a finding that is also remarkable ( p<.05). 5. The E.Q difference between the men and women who joined in both activities of sports & speciality aptitude was found existing, the total E.Q. average for women was resulted 214.2 points, which was 9.2 points higher than men of 205.0. As for the E.Q. causing points, which, without exeption of main causes, women's was reported being high than that of men, in special is more remarkable in terms of feeling control, a finding that deserves an attention. ( p<.05).

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Fertilizer Recommendation Based on Soil Testing for Tomato in Plastic Film House (토양검정에 의한 시설재배 토마토의 적정 시비량 추천)

  • Hong, Soon-Dal
    • Korean Journal of Soil Science and Fertilizer
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    • v.31 no.4
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    • pp.350-358
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    • 1998
  • To determine the optimum application of fertilizers for the cultivation of tomato in plastic film house, eighteen soils which contained different salt contents were taken from four different areas under plastic film house cultivation, Youngdong, Boeun, Cheongweon county, and Cheongju city. The dry weight and the amount of N, P, and K uptakes of tomato in the plot with no fertilization were considered as the factors representing the fertility of the soil. The differences in the dry weight and in the amounts of N, P, and K uptakes of plants between the plots with fertilization and with no fertilization were considered as the factors representing the total effect of fertilizer and the effects of fertilizer N, P, and K, respectively. These factors of soil fertility and fertilizer effects were estimated by correlation and regression with the chemical properties of the soil in order to find the critical levels and recommended method for optimum fertilization of tomato. The standardized partial regression coefficients of inorganic nitrogen ($NO_3-N+NH_4-N$) contents in soil for the factors of fertility ranged from 247 to 1,159, showing the best, while those of the others ranged from 0.02 to 4.02. Those of inorganic nitrogen ($NO_3-N+NH_4-N$) contents in soil for the electrical conductivity were also the best and were ranged from 35.2 to 36.0 compared with the values of less than 1.0 of the others. These results demonstrate that the content of inorganic nitrogen in the soil is the best index for both soil fertility and electrical conductivity of the soil. The critical level of inorganic nitrogen ($NO_3-N+NH_4-N$) in the soil for maximum productivity with zero value of fertilizer effects for tomato, estimated through Cate-Nelson split method was $220mg\;kg^{-1}$. This was the same value as evaluation for the cultivation of chinese cabbage. In conclusion, for optimal application of fertilizer in plastic film house, 1) no fertilization is recommended when the contents of inorganic nitrogen in the soil is more than $220mg\;kg^{-1}$; however, 2) in the case of less than $220mg\;kg^{-1}$ of inorganic nitrogen content in the soil, the optimal level of fertilization could be estimated through the regression equation between fertilizer effects and content of inorganic nitrogen in the soil.

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The Effect of Instruction for 'Family Life Planning' based on Backward Design on Learners' Understanding and Satisfaction (백워드 수업설계를 적용한 '가족생활 설계' 영역 수업이 학습자의 이해도 및 수업만족도에 미치는 효과)

  • Yoo, Se Jong;Lee, Yon Suk
    • Journal of Korean Home Economics Education Association
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    • v.30 no.3
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    • pp.43-66
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    • 2018
  • The purpose of this study was to conduct the instruction for 'Family Life Planning' based on backward design and measured the learners' understanding and satisfaction for testing validity. In short, the result of this study are as follows: In this study, first of all, the students could explain significant concepts, knowledge, and principles for the planning of family life; they could interpret and apply them; they have perspectives on them; they could empathize them; and they could have self-knowledge. The students could also accomplish high achievements for important concepts related to the field of family life planning. In conclusion, this study showed that the developed instruction was very effective for the students to achieve fruitful results, accelerating the learners' persistent understanding. Second, the learners had high satisfaction on the instruction of Family Life Planning based on backward design with the average score of 3.68 out of the perfect score 4. The students could be satisfied with the developed instruction since they could have high interest in the class thanks to diverse learning materials, and they could take an active part in the learning tasks based on group activities and questions. Also they could apply the contents that they learned through task performances to new situation and context. Therefore, this study proved that the developed instruction enhanced the learners' satisfaction on class.

The effects of the number of times dipped in coloring liquid and final sintering temperature on flexural strength of zirconia ceramics: Zirconia ceramics having improved transparency (착색액 침지 횟수와 최종 소결 온도가 지르코니아 세라믹의 굴곡강도에 미치는 영향)

  • Kong, Moon-Chun;Kim, Kap-Jin;Kown, Tae-Yub;Hong, Min-Ho
    • Korean Journal of Dental Materials
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    • v.44 no.2
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    • pp.171-178
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    • 2017
  • The purpose of this study is to investigate the effect of number of times dipped in coloring liquid and sintering temperature on the flexural strength of zirconia ceramic. In this study, using a zirconia block having improved transparency, specimens with size of $25mm{\times}2mm{\times}1.5mm$ were fabricated. The zirconia ceramic specimens were divided into three groups according to the number of times dipped in coloring liquid by 0, 2 and 4 times, and dyed in the coloring liquid to give color to each specimen. Then, after sintering them at the final temperature of $1,450^{\circ}C$ and $1,600^{\circ}C$, flexural strength was measured using a universal testing machine (total 6 group, n=10 for each group). Also, a scanning electron microscopy (SEM) was performed to observe its microstructure, and the data obtained through the experiment were analyzed with two-way ANOVA. The results of the flexural strength analysis show that the highest value was measured $762.3{\pm}42.3MPa$ in EKL2 group, while the lowest value was $516.4{\pm}77.1MPa$ in EKH4 group. According to the results of the two-way ANOVAs, flexural strength was not related with interaction between sintering temperature and number of times dipped in coloring liquid ($R^2=0.737$). However, there were statistically significant differences in flexural strength depending on sintering temperature (P<0.001). The flexural strength of zirconia ceramics having improved transparency was dependent on sintering temperature. The number of times dipped in the coloring liquid did not affect flexural strength of the zirconia ceramic having improved transparency.

Prediction of Expected Residual Useful Life of Rubble-Mound Breakwaters Using Stochastic Gamma Process (추계학적 감마 확률과정을 이용한 경사제의 기대 잔류유효수명 예측)

  • Lee, Cheol-Eung
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.31 no.3
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    • pp.158-169
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    • 2019
  • A probabilistic model that can predict the residual useful lifetime of structure is formulated by using the gamma process which is one of the stochastic processes. The formulated stochastic model can take into account both the sampling uncertainty associated with damages measured up to now and the temporal uncertainty of cumulative damage over time. A method estimating several parameters of stochastic model is additionally proposed by introducing of the least square method and the method of moments, so that the age of a structure, the operational environment, and the evolution of damage with time can be considered. Some features related to the residual useful lifetime are firstly investigated into through the sensitivity analysis on parameters under a simple setting of single damage data measured at the current age. The stochastic model are then applied to the rubble-mound breakwater straightforwardly. The parameters of gamma process can be estimated for several experimental data on the damage processes of armor rocks of rubble-mound breakwater. The expected damage levels over time, which are numerically simulated with the estimated parameters, are in very good agreement with those from the flume testing. It has been found from various numerical calculations that the probabilities exceeding the failure limit are converged to the constraint that the model must be satisfied after lasting for a long time from now. Meanwhile, the expected residual useful lifetimes evaluated from the failure probabilities are seen to be different with respect to the behavior of damage history. As the coefficient of variation of cumulative damage is becoming large, in particular, it has been shown that the expected residual useful lifetimes have significant discrepancies from those of the deterministic regression model. This is mainly due to the effect of sampling and temporal uncertainties associated with damage, by which the first time to failure tends to be widely distributed. Therefore, the stochastic model presented in this paper for predicting the residual useful lifetime of structure can properly implement the probabilistic assessment on current damage state of structure as well as take account of the temporal uncertainty of future cumulative damage.

Effects of primers on the microtensile bond strength of resin cements to cobalt-chromium alloy (레진 시멘트와 코발트 크롬 합금의 미세인장결합강도에 다양한 프라이머들이 미치는 영향)

  • Jung, Hong-Taek;Campana, Shiela A.;Park, Jin-Hong;Shin, Joo-Hee;Lee, Jeong-Yol
    • The Journal of Korean Academy of Prosthodontics
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    • v.57 no.2
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    • pp.95-101
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    • 2019
  • Purpose: The aim of this study is to evaluate the effects of various primers on the microtensile bond strength (${\mu}TBS$) of resin cements to cobalt-chromium (Co-Cr) dental casting alloy. Materials and methods: Four adhesive primers (Universal primer, Metal primer II, Alloy primer, and Metal/Zirconia primer) and two resin cements (Panavia F2.0, G-CEM LinkAce) were tested. One hundred fifty Co-Cr beams were prepared from Co-Cr ingots via casting ($6mm\;ength{\times}1mm\;width{\times}1mm\;thick$). The metal beams were randomly divided into ten groups according to the adhesive primers and resin cements used; the no-primer groups served as the control (n = 15). After sandblasting with aluminum oxide ($125{\mu}m$ grain), the metal and resin cements were bonded together using a silicone mold. Prior to testing, all metal-resin beams were examined under stereomicroscope, and subjected to the ${\mu}TBS$ test. The mean value of each group was analyzed via one-way ANOVA with Tukey's test as post hoc (${\alpha}=.05$) using SPSS software. Results: The mean ${\mu}TBS$ of all groups was ranged from 20 to 28 MPa. There is no statistically significant difference between groups (P > .05). Mixed failure, which is the combination of adhesive and cohesive failures, is the most prevalent failure mode in both the Panavia F2.0 and G-Cem LinkAce groups. Conclusion: The ${\mu}TBS$ of all tested groups are relatively high; however, the primers used in this study result in no favorable effect in the ${\mu}TBS$ of Panavia F2.0 and G-Cem LinkAce resin cement to Co-Cr alloy.

Application Effect of the Controlled Release Fertilizer Applied on Seedling Tray at Seeding Time in Rice (벼 모판 파종동시처리 완효성비료 시용효과)

  • Won, Tae-Jin;Choi, Byoung-Rourl;Cho, Kwang-Rae;Lim, Gab-June;Chi, Jeong-Hyun;Woo, Sun-Hee
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.64 no.3
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    • pp.204-212
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    • 2019
  • The optimal application rate of a controlled release fertilizer (CRF) on the growth, yield, and seeding time of rice grown on seedling trays was investigated. The experimental field was located at $37^{\circ}22^{\prime}10^{{\prime}{\prime}}N$ latitude and $127^{\circ}03^{\prime}85^{{\prime}{\prime}}E$ longitude in Hwaseong, Gyeonggi-do, Republic of Korea. The soil in the paddy field was a clay loam. The CRF used in the experiment contained $300g\;kg^{-1}$ of nitrogen, $60g\;kg^{-1}$ of phosphate, and $60g\;kg^{-1}$ of potassium, respectively. The CRF was applied at the rate of 0, 200, 300, 400, 500, and 600 grams on rice seedling tray compared with the field application based on soil testing (control), respectively. The CRF can be applied as single application(which can replace basal fertilizer application and two top dressing application) directly to the seedling tray, and showed the minimum release at the seedling period. Considering the plant growth, nitrogen use efficency and yield of rice, the optimal application rate of developed CRF was 500 g per seedling tray and the yield of rice at this application rate was $4.92{\sim}5.04Mg\;ha^{-1}$. The regression formula between the rice yield and application rates of CRF was as follows ; "$Y=0.0002{\chi}^2+0.0963{\chi}+411.6$($R^2$ : 0.9922) in 2010 and $Y=8E-6{\chi}^2+0.2723{\chi}+344.04$($R^2$:0.9864) in 2011, Y : Rice yield ($Mg\;ha^{-1}$), ${\chi}$ : Application rate (grams) of controlled release fertilizer". The optimum application rates of CRF per rice seedling tray by regression formula was 498 grams in 2010 and 513 grams in 2011.

A study of the tensile bond strength between Polyetherketoneketone (PEKK) and various veneered denture base resin (Polyetherketoneketone (PEKK)과 다양한 의치상용 전장 레진 간의 인장결합강도에 관한 연구)

  • Park, Yeon-Hee;Seo, Jae-Min;Lee, Jung-Jin
    • The Journal of Korean Academy of Prosthodontics
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    • v.60 no.3
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    • pp.231-238
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    • 2022
  • Purpose. This study aimed to investigate the effect of different veneering methods on the tensile bond strength between polyetherketoneketone (PEKK) and denture base resins. Materials and methods. A total of 80 PEKK T-shaped specimens were fabricated and the primer (Visio.link) was applied after airborne-particle abrasion with 110 ㎛ alumina oxide powder. According to the veneering method, the specimens were divided into four groups (n = 20) to be veneered with the gingival colored packable photopolymerized composite resin (SR Adoro); flowable photopolymerized composite resin, (Crea.lign); heat-polymerized resin (Vertex); and self-polymerized resin (ProBase Cold). Each group was divided into two subgroups (n = 10) according to the artificial thermal aging. After the tensile bond strength measurement via universal testing machine, the fracture sections of all specimens were observed. Two-way ANOVA and Tukey's HSD post hoc test were used for the statistical analysis (α = .05). Results. The results of the two-way ANOVA showed statistically significant differences in the tensile bond strength according to the veneering method and artificial thermal aging of denture base resins (P<.001). The highest tensile bond strength showed in the packable photopolymerized resin group before and after the artificial thermal aging. The lowest tensile bond strength showed in the heat-polymerized resin group. The mixed and adhesive fracture showed in all groups. Conclusion. The veneering method and artificial thermal aging can influence in the tensile bond strength between the resin and PEKK. The artificial thermal aging can reduce the tensile bond strength.