• 제목/요약/키워드: terminal groups

검색결과 410건 처리시간 0.028초

Age-related Reference Intervals for Total Collagen-I-N-terminal Propeptide in Healthy Korean Population

  • Yoo, Jun-Il;Park, Ae-Ja;Lim, Yong Kwan;Kweon, Oh Joo;Choi, Jee-Hye;Do, Jae Hyuk;Kim, Sunjoo;Kim, Youngri;Ha, Yong-Chan
    • 대한골대사학회지
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    • 제25권4호
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    • pp.235-241
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    • 2018
  • Background: Procollagen type I N-terminal propeptide (PINP) is one of the most clinically useful bone formation biomarkers. Therefore, the purpose of this study was to independently evaluate the performance of automated total PINP assay and established age- and gender- specific reference intervals for PINP in healthy Korean population. Methods: The imprecision, linearity, and detection capability of Elecsys total PINP assay was determined and reference interval was established using 599 serums from Korean population with normal bone mineral densities based on bone densitometry. Age groups were divided into 20s, 30s, 40s, 50s, 60s and over. Results: Elecsys total PINP had excellent performance in imprecision, linearity, and detection capability. When partitioning age groups in Korean male and female populations, there was significant difference in total PINP between different age groups. In male populations, PINP level was decreased with increasing age, then it remained steady after middle-age. In female populations, there was a decreasing tendency similar to that in the male population with a sharp increase in the 50 to 59 age group. Conclusions: Elecsys total PINP assay showed precise and reliable performance in our study. We established age-related PINP reference intervals for Korean male and female population with normal bone mineral densities.

Generalized Stability Criterion for Multi-module Distributed DC System

  • Liu, Fangcheng;Liu, Jinjun;Zhang, Haodong;Xue, Danhong
    • Journal of Power Electronics
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    • 제14권1호
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    • pp.143-155
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    • 2014
  • The stability issues of a multi-module distributed DC power system without current-sharing loop are analyzed in this study. The physical understanding of the terminal characteristics of each sub-module is focused on. All the modules are divided into two groups based on the different terminal property types, namely, impedance (Z) and admittance (Y) types. The equivalent circuits of each group are established to analyze the stability issues, and the mathematical equations of the equivalent circuits are derived. A generalized criterion for multi-module distributed systems is proposed based on the stability criterion in a cascade system. The proposed criterion is independent of the power flow direction.

Synthesis of 2-Substituted Benzofurans from o-Iodophenols and Terminal Alkynes with a Recyclable Palladium Catalyst Supported on Nano-sized Carbon Balls under Copper- and Ligand-Free Conditions

  • Yum, Eul Kgun;Yang, Ok-Kyung;Kim, Ji-Eun;Park, Hee Jung
    • Bulletin of the Korean Chemical Society
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    • 제34권9호
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    • pp.2645-2649
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    • 2013
  • We have developed a one-step synthesis of benzofurans from o-iodophenol and various terminal alkynes, by using Pd catalyst supported on nano-sized carbon balls (NCB) under copper- and ligand free conditions. This recyclable catalyst could be reused more than 5 times in the same heteroannulation reaction. The results have demonstrated that diverse 2-substituted benzofurans with tolerant functional groups can be prepared simply and conveniently under these conditions.

Applications of Tandem Mass Spectrometry in the Structure Determination of Permethylated Sialic Acid-containing Oligosaccharides

  • Yoo, Eun-Sun;Yoon, In-Mo
    • Bulletin of the Korean Chemical Society
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    • 제26권9호
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    • pp.1347-1353
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    • 2005
  • Sets of sialic acid-containing trisaccharides having different internal and terminal linkages have been synthesized to develop a sensitive method for analysis of the reducing terminal linkage positions. The trisaccharides, sialyl($\alpha$ 2-3)Gal($\beta$ 1-3)GalNAc and sialyl($\alpha$ 2-3)Gal($\beta$ 1-X)GlcNAc where X=3, 4 and 6, were synthesized and examined using electrospray ionization (ESI)-collision induced dissociation (CID) tandem mass spectrometry (MS/MS). The compounds chosen for this study are related to terminal groups likely to be found on polylactosamine-like glycoproteins and glycolipids which occur on the surface of mammalian cells. The purpose of this study is to develop tandem mass spectrometral methods to determine detailed carbohydrate structures on permethylated or partially methylated oligosaccharides for future applications on biologically active glycoconjugates and to exploit a faster method of synthesizing a series of structural isomeric oligosaccharides to be used for further mass spectrometry and instrumental analysis.

Synthesis and Liquid Crystalline Properties of Hyperbranched Aromatic Polyesters Consisting of Azoxybenzene Mesogens and Polymethylene Spacers

  • Park, Young-Suk;Lee, Jun-Woo;Jin, Jung-Il
    • Bulletin of the Korean Chemical Society
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    • 제23권9호
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    • pp.1201-1210
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    • 2002
  • A new series of hyperbranched aromatic polyesters containing azoxybenzene mesogens and polymethylene spacers were prepared by polymerizing AB2 type monomers that have the isophthaloyl dicarboxylic acid terminal at one end and the p-oxyp henol terminal at the other end. The monomers contain a built-in azoxybenzene mesogen that is linked to the terminal groups through polymethylene spacers. The polyesters prepared were characterized by solution viscosity, differential scanning calorimetry, X-ray diffractometry and polarizing microscopy. All of the polyesters were found to be thermotropic (nematic). Their glass-transition temperatures and mesophase temperature ranges were very sensitive to the length of the two spacers existing in the repeating unit. The degree of branching of one of the polyesters was determined by the NMR spectroscopy and found to be 0.56.

Kidney transplantation using expanded criteria deceased donors with terminal acute kidney injury: a single center experience in Korea

  • Ko, Kyung Jai;Kim, Young Hwa;Kim, Mi Hyeong;Jun, Kang Woong;Kwon, Kyung Hye;Kim, Hyung Sook;Kim, Sang Dong;Park, Sun Cheol;Kim, Ji Il;Yun, Sang Seob;Moon, In Sung;Hwang, Jeong Kye
    • Annals of Surgical Treatment and Research
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    • 제95권5호
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    • pp.278-285
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    • 2018
  • Purpose: We investigated the clinical outcomes of deceased donor kidney transplantation (KT) using kidneys with terminal acute kidney injury (AKI). Methods: Between February 2000 and December 2013, we performed 202 deceased donor renal transplants from 159 brain dead donors. According to the expanded criteria donor (ECD) and AKI network criteria, we divided 202 recipients into 4 groups: Group I: Non-AKI & standard criteria donor (SCD) (n = 97); group II: Non-AKI & ECD (n = 15); group III: AKI & SCD (n = 52); and group IV: AKI & ECD (n = 38). Results: The incidence of delayed graft function (DFG) was significantly higher in patients with AKI than it was in the non-AKI group (P = 0.008). There were no significant differences among the 4 groups in graft survival (P = 0.074) or patient survival (P = 0.090). However, the long-term allograft survival rate was significantly lower in group IV than it was in other groups (P = 0.024). Conclusion: Allografts from deceased donors with terminal AKI had a higher incidence of DGF than did those from donors without AKI. However, there is no significant difference in graft and patient survival rates among the groups. So, the utilization of renal grafts from ECDs with terminal AKI is a feasible approach to address the critical organ shortage.

의미요법이 청소년 후기 말기 암환자의 생의 의미와 삶의 질에 미치는 효과 (The Effects of Logotherapy on Meaning in Life and Quality of Life of Late Adolescents with Terminal Cancer)

  • 강경아;심정숙;전대근;고명숙
    • 대한간호학회지
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    • 제39권6호
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    • pp.759-768
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    • 2009
  • Purpose: To evaluate the effects of a logotherapy program entitled 'Finding meaning in my life' for adolescents with terminal cancer. Methods: A nonequivalent control group, non-synchronized design was conducted with a convenience sample of 44 late adolescents with terminal cancer. The experimental group (n=22) participated in the 'Finding meaning in my life' program which consisted of five-day sessions for one week. The control group (n=22) received the usual nursing care. The effects were measured using adolescent meaning in life (AMIL), and quality of life (QOL) scales. The collected data were analyzed by descriptive statistics, Chi-square, and t-test using SPSS/PC 17.0 program. Results: There were significant differences in AMIL (t=3.36, p<.05) and QOL (t=2.67, p<.05) between the experimental and control groups. Conclusion: Logotherapy is effective in improving the meaning in life and quality of life of late adolescents with terminal cancer, and can be used to prevent existential distress.

부산항 컨테이너터미널 통합운영 효과측정을 위한 시뮬레이션 연구 (A Simulation Study on the Integrated Operational Effect Measurement of the Container Terminal in Busan Port)

  • 신재영;이장군
    • 한국항해항만학회:학술대회논문집
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    • 한국항해항만학회 2019년도 춘계학술대회
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    • pp.140-141
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    • 2019
  • 부산항은 소규모로 분산된 다수의 컨테이너터미널 운영사에 의해 비효율적으로 운영되고 있다. 특히 2016년 선사들이 얼라이언스가 대형화됨에 따라 부산항의 소규모 터미널은 물량의 분산과 타부두 환적화물 증가 및 선박이 바다에서 대기하는 체선 발생을 야기시키는 원인이 되고 있다. 이에 따라 컨테이너터미널의 대형화를 위한 통합운영과 같은 연구가 진행되고 있다. 따라서 본 연구에서는 부산항 신항의 터미널들을 대상으로 통합운영의 유형을 설정하고 시뮬레이션을 통한 실질적인 효과를 측정하여 통합운영의 이상적인 방향을 제시하는 연구를 하고자한다.

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The Effects of Aroma Foot Baths on Stress and Sleep in Terminal Cancer Patients

  • Kim, Bok Soon;Chae, Sun Hwa;Hwang, In Cheol
    • Journal of Hospice and Palliative Care
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    • 제24권2호
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    • pp.109-115
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    • 2021
  • Purpose: This study aimed to investigate the effects of aroma foot baths on stress and sleep in terminally ill cancer patients. Methods: We performed a non-randomized intervention-control study with 30 terminal cancer patients who were admitted to a palliative care unit. Participants responded to questionnaires on stress and sleep before and after a 5-day interval. The intervention group received a daily aroma foot bath for 5 days. We performed multivariate regression analysis to examine the changes in outcomes on stress and sleep for the intervention group compared to the control group. Results: The differences in baseline characteristics between groups, excluding subjective economic status and general weakness, did not show statistical significance. In contrast to the control group, the intervention group showed a statistically significant change in physical stress and psychological stress levels, but significant changes were not observed in quality of sleep. Compared to the control group, the intervention group showed a significant reduction in physical stress (P=0.068) and psychological stress (P=0.021). Conclusion: Aroma foot baths are effective for reducing stress in patients hospitalized with terminal cancer.