• Title/Summary/Keyword: terminal groups

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Morphological Changes in the Mammary Organ Culture of the Rat Treated with 7,12-Dimethylbenz[$\alpha$]anthracene and N-methyl-N-nitrosourea (7,12-Dimethylbenz[$\alpha$anthracene 및 N-methyl-N-nitrosourea를 투여한 랫드 유선 조직 배양에 대한 형태학적 변화)

  • 문지영;정자영;김옥희;이형환
    • Toxicological Research
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    • v.16 no.4
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    • pp.275-284
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    • 2000
  • The organ culture model of the whole mammary gland has many advantages for the study of branching morphogenesis and biological characteristics, including tumorigenesis. Prior to whole gland organ culture, rats were treated with 7,12-dimethylbenz[a]anthracene (DMBA) or N-methyl-N-nitrosourea (MNU) for one week. The tramdorming effect and the morphological changes were assessed by the whole mount preparations and histopathological examination in terminal end buds (TEB), terminal ducts (TD), alveolar buds (AB), alveolar lobules (AL) and hyperplastic alveolar nodules (HAN) of the mammary gland. Grossfindings of the mammary glands at dissection were higher branching morphogenesis and larger volume in carcinogen-treated groups than in carcinogen-non-treated groups. Results of the whole mount method were coincided with those of the histopathological observations. Circular TEB, normally maintained AB, AL, and high cellular density were more frequently observed in carcinogen-treated groups than in carcinogen-nan-treated groups. Histopathologically, as a preneoplastic marker, HAN was maintained only in mammary organ culture of the carcinogen-treated groups. These findings suggest that in vivo trans-formation effects by carcinogens persisted during the mammary organ culture. These results were more characteristic in DMBA than in MNU-treated group. Ducts and terminal ducts appeared to have lost morphology during their growths in case of without diethylstilbestrol (DES). The fact that in vitro organ culture without DES was resulted in abnormal ductular morphogenesis confirms that DES is a physiological regulator of ductular epithelial cell growth.

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Effect of Using Smartphones for Tele-rehabilitation on Head Position and Neck Dysfunction in Workers with Visual Display Terminal Syndromes (스마트폰을 이용한 원격 재활이 영상표시단말기 작업자의 머리 위치 및 목 기능장애에 미치는 영향)

  • So, Yun-Ho;Kwon, Gi-Hwan;Kim, Tae-Ho;Cho, Jeong-Min;Lim, Jae-Heon
    • PNF and Movement
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    • v.15 no.2
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    • pp.149-157
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    • 2017
  • Purpose: The purpose of this study was to assess the effect of using smartphones for tele-rehabilitation on head position and neck dysfunction in workers with visual display terminal (VDT) syndromes over a four-week period. Methods: Sixteen VDT workers volunteered to participate in stretch exercise and posture education sessions. The subjects were divided into three groups as follows: five subjects in the visit group (VSG), six subjects in the video group (VEG), and five subjects in tele-rehabilitation group (TG). The subjects in all the groups performed the exercises three days per week for four weeks. Cranial rotation angle (CRA), craniovertebral angle (CVA) measurement, and neck disability index (NDI) tests were performed before and four weeks after the intervention. Results: No significant difference in the CRA and CVA variables was found among groups. No significant difference in the CRA variable was found within each group. A significant difference in the CRA variable was found in the VSG after the four-week intervention. No significant difference in NDI was found among the groups. The NDIs among all the groups were significantly decreased after the intervention when compared with the NDIs measured before the intervention. Conclusion: The use of smartphones in the tele-rehabilitation of VDT workers with neck pain was found to be as effective on neck function as the conventional intervention method. The tele-rehabilitation of VDT workers with neck dysfunctions may be presented as an alternative way.

Analysis of Market and Management for Global Container Terminal Operators (글로벌 컨테이너 터미널 운영사의 시장 및 경영 현황 분석)

  • Lee, Joo-Ho;Won, Seung-Hwan;Choi, Na-Young-Hwan;Yun, Won-Young
    • Journal of Korea Port Economic Association
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    • v.32 no.3
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    • pp.47-66
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    • 2016
  • Once it has been built, a container terminal is impossible to move to another location. It is hard to rectify wrong decisions in a container terminal. This highlights the importance of decision making for a container terminal. The port management about a container terminal has developed from a cargo interface location between sea and land transport, to the standardization of information and procedures due to globalization among global shipping and terminal operators. This research focuses on the current states of market and management for global container terminal operators by investigating up-to-date data for them. The current market states for global container terminal operators are analyzed by using by Herfindahl-Hirschman Index. The analyses of current management states for global container terminal operators are divided into profitability analysis, activity analysis, and bankruptcy risk analysis. Finally, global container terminal operators are clustered into three groups by the current management states.

Effects of Spiritual Nursing Care on Loneliness and Spiritual Well-Being of Terminal Cancer Patients (영적 간호가 말기 암환자의 외로움과 영적 안녕에 미치는 효과)

  • Yoon, Me-Ok
    • Journal of Home Health Care Nursing
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    • v.16 no.1
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    • pp.31-39
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    • 2009
  • Purpose: This study utilized a non-equivalent control group pre-post design to assess the effects of spiritual nursing care on loneliness and spiritual well-being of terminal cancer patients. Method: Forty-one terminal cancer patients in a general hospital, were divided into an experimental group of 20 patients and a control group of 21 patients. Those in the experimental group received four weeks of treatment three times a week for about 45 minutes each session. The treatment included nurses' spiritual care involving five instruments of spiritual nursing intervention, each of which was used according to the six types of spiritual need assessment. Data was analyzed with descriptive statistics including real number, percentage, $X^2$-test, t-test, and ANCOVA. Result: There were significant differences between the experimental and control groups in the level of loneliness and spiritual well-being. Conclusion: Spiritual nursing care was verified as an effective program that can lessen the loneliness and improve the spiritual well-being of patients with terminal cancer.

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Synthesis and Characterization of Aliphatic Hyperbranched Polyesters (지방족 고차가지구조 폴리에스테르의 합성 및 물성)

  • Kim Jang-Yup;Ok Chang-Yul;Lee Sang-Won;Huh Wansoo
    • Polymer(Korea)
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    • v.29 no.6
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    • pp.575-580
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    • 2005
  • The hydroxy terminated aliphatic hyperbranched polyesters having different generations were synthesized by using melt polycondensation procedure. Then, the terminal groups of hyperbranched polyesters were modified by using acryloyl chloride and characterized by $\^{1}H$-NMR and GPC techniques. As a result of the modification of terminal groups for hyperbranched polyesters, the phase of the polymers were changed from sticky solid to high viscous liquid indicating that the glass transition temperatures of modified hyperbranched polyesters were lower than the original one. The thermal stabilities of hydroxy terminated hyperbranched polyesters were higher than those of terminal group-modified polymers.

The analysis on the screen design of terminal display (터미날 화면의 설계 특성에 관한 비교분석)

  • 황우상;이동춘
    • Proceedings of the ESK Conference
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    • 1995.10a
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    • pp.62-74
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    • 1995
  • This study surveys four characteristics (overall density, local density, grouping, complexity) to effect user's performance on the on-line terminal displays of commercial banks, and makes the new screen by the screen design procedure. The new screen includes to increase the number of groups and to arrange the items on the screen. And then, this study carrys out experiments to compare performance(operating time and error number ) by each screen. The result is described that the operating time decreases about 20% at the new OUT-screen than the existing OUT-screens; about 25% at the new IN-screen.

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Adaptive second-order nonsingular terminal sliding mode power-level control for nuclear power plants

  • Hui, Jiuwu;Yuan, Jingqi
    • Nuclear Engineering and Technology
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    • v.54 no.5
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    • pp.1644-1651
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    • 2022
  • This paper focuses on the power-level control of nuclear power plants (NPPs) in the presence of lumped disturbances. An adaptive second-order nonsingular terminal sliding mode control (ASONTSMC) scheme is proposed by resorting to the second-order nonsingular terminal sliding mode. The pre-existing mathematical model of the nuclear reactor system is firstly described based on point-reactor kinetics equations with six delayed neutron groups. Then, a second-order sliding mode control approach is proposed by integrating a proportional-derivative sliding mode (PDSM) manifold with a nonsingular terminal sliding mode (NTSM) manifold. An adaptive mechanism is designed to estimate the unknown upper bound of a lumped uncertain term that is composed of lumped disturbances and system states real-timely. The estimated values are then added to the controller, resulting in the control system capable of compensating the adverse effects of the lumped disturbances efficiently. Since the sign function is contained in the first time derivative of the real control law, the continuous input signal is obtained after integration so that the chattering effects of the conventional sliding mode control are suppressed. The robust stability of the overall control system is demonstrated through Lyapunov stability theory. Finally, the proposed control scheme is validated through simulations and comparisons with a proportional-integral-derivative (PID) controller, a super twisting sliding mode controller (STSMC), and a disturbance observer-based adaptive sliding mode controller (DO-ASMC).

Synthesis, End-Functionalization and Characterization of Hyperbranched Polysiloxysilanes from $AB_3$ Type Monomer

  • Ishida, Yoshihito;Yokomachi, Kazutoshi;Seino, Makoto;Hayakawa, Teruaki;Kakimoto, Masa-aki
    • Macromolecular Research
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    • v.15 no.2
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    • pp.147-153
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    • 2007
  • Hyperbranched polysiloxysilanes (HBPSs), with a variety of terminal functional groups (vinyl, epoxy, carboxyl and hydroxyl), were synthesized by the self-polymerization of an $AB_3$ type monomer of tris(dimethylvinylsiloxy) silane, with subsequent end-functionalizations, such as epoxidation and radical addition reaction, respectively. The ratio of the $\alpha-and$ $\beta-addition$ linkages in the HBPS polymerized by hydrosilylation of the $AB_3$ monomer was found to be approximately 1 to 3. The thermal stability and solubility were affected by the terminal functional groups.

Photoresponsive Azobenzene-cored Dendrons with Terminal Vinyl Groups

  • Choi, Dae-Ock;Lee, Ji-Hye;Shin, Kyong-Ha;Shin, Eun-Ju
    • Bulletin of the Korean Chemical Society
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    • v.28 no.6
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    • pp.983-989
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    • 2007
  • Azobenzene-cored dendrons having the photoisomerizable azobenzene core and terminal vinyl groups have been prepared. Absorption bands of azobenzene-cored dendrons are similar except more intense 280 nm band in higher generation azobenzene dendron. All three azobenzene-cored dendrons show reversible photoisomerization similar to simple azobenzene, irrespective of the generation of dendron. On 350 nm irradiation, absorption band around 344 nm decreases and 436 nm band increases. Photoisomerization reactions are very fast for all three azobenzene-cored dendron and the reaction efficiency is dependent of its generation and solvent. In the dark, slow thermal reversion to original absorption spectrum is observed.

Purification of the NADH Reductase Component of the Steroid $9{\alpha}$-hydroxylase from Mycobacterium fortuitum

  • Kang, Hee-Kyoung;Lee, Sang-Sup
    • Archives of Pharmacal Research
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    • v.20 no.6
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    • pp.590-596
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    • 1997
  • The NADH reductase component of the steroid 9.alpha.-hydroxylase from Mycobacterium fortuitum was purified to homogeneity. Recovery of the enzyme from the 50-60% ammonium sulfate saturated fraction was 49%, with a purification factor of 100-fold. The NADH reductase has a relative molecular of 60 KDa as determined by SDS-PAGE. The absorption maxima at 410 and 450 nm indicate the presence of iron-sulfur group and flavin. These prosthetic groups seemed to function as redox groups that transfer electrons from NADH to the following protein. The $K_M$ value for NADH as substrate was $68{\mu}M$. The $NH_2$-terminal amino acid sequence of the reductase was determined as Met-Asp-Ala-Ile-Thr-Asn-Val-Pro-Leu-Pro-Ala-Asn-Glu-Pro-Val-His-Asp-Tyr-Ala-Thr. This sequence does not show a homology with the $NH_2$ -terminal sequences reported for the reductase component of other monooxygenases, suggesting that the NADH reductase component of the steroid 9.alpha.-hydroxylase system is novel.

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