• Natural Product Sciences
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• v.16 no.3
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• pp.192-197
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• 2010

The seeds of Raphanus sativus L. (RSL) and Phaseolus calcaratus Roxburgh (PHCR), the root of Scutellaria baicalensis (SB), and the flower of Lonicera japonica (LJ) have been traditionally used as herbal medicines for anti-inflammation. Unlike the SB and LJ, little information is available for the scientific bases that show the anti-inflammatory mechanisms of RSL and PHCR. In this study, we prepared boiled water extracts from the medicines and determined their potentials in inhibiting nitric oxide (NO) production, cyclooxygenase-2 (COX-2) expression, and tumor necrosis factor (TNF)-$\alpha$ and interleukin (IL)-6 secretion in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. The effects of the medicines on serum IgE levels in ovalbumin (OVA)-administrated mice were also studied. The medicines inhibited production of TNF-$\alpha$ and IL-6, and COX-2 expression in LPSstimulated macrophages. Especially, PHCR water extract showed more potent inhibition on TNF-$\alpha$ production than SB and LJ extracts, but RSL extract did not exert these effects. Similar to the cases of SB and LJ, PHCR extract prevented the phosphorylation of $I{\kappa}B{\alpha}$ and c-Jun, and the activation of NF-${\kappa}B$-DNA binding. Further, oral supplementation of PHCR extract attenuated significantly serum levels of total and OVA-specific IgE in OVAtreated animals. These results suggest a possibility that PHCR water extract can be used for the treatment of inflammatory and allergic diseases.

• Natural Product Sciences
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• v.16 no.3
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• pp.169-174
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• 2010

The seed of Phaseolus calcaratus Roxburgh (PHCR) is traditionally used for anti-pyretic and antiinflammatory effects. Although these effects are believed to be related to its antioxidant potential, little information is available for the mechanisms by which PHCR seed might scavenge free radicals or otherwise act as an antioxidant. In the present study, we purified some fractions from the ethanol extract of PHCR seed and evaluated each fraction's ability to scavenge free radicals generated by cell-free systems. We also identified active compound that is putatively responsible for free radical scavenging by analyzing NMR spectra. PHCR samples exhibited a concentration-dependent radical scavenging activity against hydroxyl radicals, superoxide anions, and DPPH radicals. Of the samples tested, a methanol-eluted sub-fraction from the PHCR extract, named $FF_4$, scavenged these radicals more effectively than the other fractions. We identified catechin-7-O-$\beta$-Dglucopyranoside as the active compound responsible for free radical scavenging potential of $FF_4$.

• Korean Journal of Remote Sensing
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• v.36 no.5_2
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• pp.867-879
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• 2020

As the era of space technology utilization is approaching, the launch of CAS (Compact Advanced Satellite) 500-1/2 satellites is scheduled during 2021 for acquisition of high-resolution images. Accordingly, the increase of image usability and processing efficiency has been emphasized as key design concepts of the CAS 500-1/2 ground station. In this regard, "CAS 500-1/2 Image Acquisition and Utilization Technology Development" project has been carried out to develop core technologies and processing systems for CAS 500-1/2 data collecting, processing, managing and distributing. In this paper, we introduce the results of the above project. We developed an operation system to generate precision images automatically with GCP (Ground Control Point) chip DB (Database) and DEM (Digital Elevation Model) DB over the entire Korean peninsula. We also developed the system to produce ortho-rectified images indexed to 1:5,000 map grids, and hence set a foundation for ARD (Analysis Ready Data)system. In addition, we linked various application software to the operation system and systematically produce mosaic images, DSM (Digital Surface Model)/DTM (Digital Terrain Model), spatial feature thematic map, and change detection thematic map. The major contribution of the developed system and technologies includes that precision images are to be automatically generated using GCP chip DB for the first time in Korea and the various utilization product technologies incorporated into the operation system of a satellite ground station. The developed operation system has been installed on Korea Land Observation Satellite Information Center of the NGII (National Geographic Information Institute). We expect the system to contribute greatly to the center's work and provide a standard for future ground station systems of earth observation satellites.

• Journal of Korea Multimedia Society
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• v.19 no.2
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• pp.411-417
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• 2016

Since the development of Graphic Processing Unit (GPU) in 1999, the development speed of GPUs has become much faster than that of CPUs and currently, the computational power of GPUs exceeds CPUs dozens and hundreds times in terms of decimal calculations and costs much less. Owing to recent technological development of hardwares, general-purpose computing and utilization using GPUs are on the rise. Thus, in this paper, we have identified the elements to be considered for the Smart Grid Security. Focusing on a Performance Improvement of the Basic Algorithm for the Stateful Inspection to Detect DDoS Attacks using CUDA. In the program, we compared the search speeds of GPU against CPU while they search for the suffix trees. For the computation, the system constraints and specifications were made identical during the experiment. We were able to understand from the results of the experiment that the problem-solving capability improves when GPU is used. The other finding was that performance of the system had been enhanced when shared memory was used explicitly instead of a global memory as the volume of data became larger.

• Journal of the Korean Institute of Gas
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• v.26 no.4
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• pp.9-17
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• 2022

This paper is the continuation of our previous paper, which we refer to as numerical analysis of phase behavior and flow properties in an injection tubing during gas phase CO₂ injection. Our study in this paper show the results during supercritcal CO₂ injection under the same project. Geological CO₂ storage technology is one of the most effective method to decrease climate change due to high injectivity and storage capacity and economics. A demonstration-scale CO₂ storage project was performed in a deep aquifer in the Pohang basin, Korea for a technological development in a large-scale CO₂ storage project. A problem to consider in the early stage design of the project was to analyze CO₂ phase change and flow characteristics during CO₂ injection. To solve this problem, injection conditions were decided by calculating injection rate, pressure, temperature, and thermodynamic properties. For this research, we simulated and numerically analyzed CO₂ phase change from liquid to supercritical phase and flow characteristics in injection tubing using OLGA program. Our results provide discharge pressure and temperature conditions of CO₂ injection combined with a pressure of an aquifer.

• Journal of the Korea Concrete Institute
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• v.22 no.6
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• pp.787-796
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• 2010

The main reason of the earth global warming is $CO_2$ and the regulation about it in the whole world has been reinforced to reduce $CO_2$ emission. It is needed that we should reduce it in the process at the production of concrete generated much of $CO_2$ emission as the primary material of construction industry recognized unfriendly environment industry. Based on a concrete, this study was constructed the system to evaluate $CO_2$ emission generated in the stage of material production, transportation, manufacture and developed the program to reduce and evaluate it efficiently. As a result, most of $CO_2$ emission is generated in the stage of material and it is quantitatively evaluated $CO_2$ emission generated in the stage of materials, transportation and manufacture. Moreover, the evaluation system of the volume of $CO_2$ emission which has the friendly environment technology about reduction of $CO_2$ emission at each stage is suggested for quantitatively evaluation $CO_2$ emission generated in the process at the production of concrete and remicon production company could use it to evaluation $CO_2$ emission.

• Journal of Plant Biotechnology
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• v.48 no.4
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• pp.289-303
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• 2021

Covid-19 is an ongoing pandemic as we speak in 2022. This infectious disease is caused by the SARS-CoV-2 virus, which infects cells by binding to the angiotensin-converting enzyme 2 (ACE2) receptor on the cell surface. Thus, strategies that inhibit the binding of SARS-CoV-2 to the ACE2 receptor can stop this contagion. Hanjeli (Coix lacryma-jobi) essential oil contains many bioactive compounds, including dodecanoic acid; tetradecanoic acid; 7-Amino-8-imino-2-(2-imino-2H-chromen-3-yl); and 1,5,7,10-tetraaza-phen-9-one. These compounds suppress viral replication and may prevent Covid-19. Accordingly, this study assessed whether, these four limonoid compounds can block the ACE2 receptor. To this end, their physicochemical properties were predicted using Lipinski's "rule of five" on the SwissADME website, and their toxicity was assessed using the online tools ProTox and pkCSM. Additionally, their interactions with the ACE2 receptor were predicted via molecular docking using Autodock Vina. All the four compounds satisfied the "rule of five" and tetradecanoic acid was predicted to have a higher affinity than the comparison compound remdesivir and the original ligand of ACE2. Molecular docking results suggested that the compounds from hanjeli essential oil interact with the active site of the ACE2 receptor similarly as the original ligand and remdesivir. In conclusion, hanjeli essential oil contains compounds predicted hinder the interaction of SARS-CoV-2 with the ACE2 receptor. Accordingly, our data may facilitate the development of a phytomedical strategy against SARS-CoV-2 infection.

• Journal of Plant Biotechnology
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• v.43 no.3
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• pp.281-292
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• 2016

Plants can recognize and respond in various ways to diverse environmental stresses, including pathogenic microorganisms, salt, drought, and low temperature. Salicylic acid (SA) is one phytohormone that plays important roles in the regulation of plant growth and development. Nonexpressor of pathogenesis-related genes 1 (NPR1) was originally identified as a core protein that could function as a transcriptional co-regulator and SA receptor during systemic acquired resistance (SAR), a plant immune response that could activate PR genes after pre-exposure of a pathogen. Although the function of NPR1 in plant defense response and the role of SA hormone in the regulation of plant physiological processes have been well characterized, the biological role of NPR1 in plant abiotic stress responses is largely unknown. In this review, we will summarize and discuss the current understanding of NPR1 function in response to plant environmental stresses.

• Journal of Mechanical Science and Technology
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• v.17 no.10
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• pp.1450-1457
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• 2003

Structural integrity of either a passenger car or a light truck is one of the basic requirements for a full vehicle engineering and development program. The results of the vehicle product performance are measured in terms of durability, noise/vibration/harshness (NVH), crashworthiness and passenger safety. The level of performance of a vehicle directly affects the marketability, profitability and, most importantly, the future of the automobile manufacturer. In this study, we used the Virtual Proving Ground (VPG) approach for obtaining the dynamic stress or strain history and distribution. The VPG uses a nonlinear, dynamic, finite element code (LS-DYNA) which expands the application boundary outside classic linear, static assumptions. The VPG approach also uses realistic boundary conditions of tire/road surface interactions. To verify the predicted dynamic stress and fatigue critical region, a single bump run test, road load simulation, and field test have been performed. The prediction results were compared with experimental results, and the feasibility of the integrated life prediction methodology was verified.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.23 no.11
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• pp.880-885
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• 2010

The Angle Ring and Cap which is called pressboard are settled at the primary and secondary coil winding of 154 kV transformer that can reduce effectively distance of insulation. As it has not manufactured pressboard of Angle Ring and Cap for high voltage grade, insulation components industry especially high voltage transformer has not participate in a competition with worldwide yet. That's why is difficult to make an specialized shape of insulation components of high voltage grade. Therefore it has finally completed to make an deformation manufacturing utility using an bellowed special analysis tools. This study that uses various analysis program determining optimum shape about insulation of Angle Ring and Cap which is related life of high voltage transformer. In addition to develop forming equipment with an specialized five steps pressing. That is also based on the mechanical strength evaluation and test, it is investigated optimized processing components.