• Title/Summary/Keyword: target water level

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Single Dose Toxicity Test of Bojungikkeehapdaechilkitang water extract in Male and Female ICR Mice (보중익기합대칠기탕(補中益氣合大七氣湯) 추출물의 ICR마우스에서 경구 단회투여독성 평가)

  • Bae, Young-Chul;Choi, Bin-Hye;Kim, Dong-Woo;Hur, Jin-Il;Kim, Dae-Jun;Byun, Joon-Seok
    • The Journal of Internal Korean Medicine
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    • v.26 no.2
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    • pp.369-378
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    • 2005
  • An herbal water extract of Bojungikkeehapdaechilkitang(BDT) was prepared to test it for single-dose and repeated-dose toxicity, genotoxicity and reproductive toxicity, and to obtain a 50% lethal dose$(LD_{50})$, approximated lethal dose(ALD), and approximated target organs for BDT. The extract was tested on female and male ICR mice according to KFDA Guideline 1999-61 at doasge level of 2000, 1000, 500, 250 and 125mg/kg/10mL In this study, clinical signs, mortalities and gross findings of principal organs were observed for 14 days of single dosing, and afterwards in some cases. The ALD and $LD_{50}$ of BDT extract obtained in this study was>2000mg/kg for both male and female ICR mice. Also, any possible digestive toxicity of BDT extract was found to be above 1000mg/kg in both male and female ICR mice. The results of this study strongly suggest that BDT extract has no toxic effect at dosage level below 500mg/kg.

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Infant target facilities and facilities for children in elementary school Comparison and Improvement of Indoor Air Quality for Research (영유아 대상 시설의 실내공기질 특성 비교 및 개선방안에 대한 연구)

  • Seo, Byong-Won;Lee, Ju-Hwa;Park, Ji-Hoon;Kang, Seon-Hong
    • Journal of Korean Society of Water and Wastewater
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    • v.27 no.5
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    • pp.591-601
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    • 2013
  • In modern society, we are living indoor at 80 - 90 % or more of the day, therefore most people are exposed to unconscious indoor air pollutants by various causes. When mother and infant, whose level of immunity are weak, are exposed to polluted indoor air, respiratory diseases and atopy can occur by the growth of bacteria. Therefore, appropriate indoor air quality management is important especially at nursery, elementary school and postpartum clinic etc. In this study, we compared the characteristics of the indoor air qualities of primary school facilities and infant facilities. In this study, seasonal effects were investigated. Also the effects of individual activity area were studied for indoor air quality. During summer season(May-August), the air qualities of each 16 elementary school and nursery school were investigated. During winter season(October-december), the air qualities of each 10 elementary school and nursery school were investigated. As a result, during winter season in 10 of 16 nursery school, $CO_2$ concentration exceeded regulation level of 1000 ppm. This resulted from the operation of heating system and poor ventilation. Also the air quality of all parameters during winter season were worse than during summer, maybe due to poor ventilation. Except HCHO, the concentrations of other parameters were higher in nursery school. This seems to result from relatively low individual activity area of nursery school than elementary school. From this research, more strong regulation for ventilation and installation of air purifier should be implemented.

Contamination Levels of Pharmaceuticals and Pesticides in the Gotjawal Regions of Jeju Island and Associated Ecotoxicities (곶자왈 지역의 의약물질과 농약의 오염수준과 생태독성영향)

  • Kang, Ha Byeong;Koh, Su Rim;Choi, Yoonsong;Lee, Sangwoo;Kho, YoungLim;Oh, Dalyoung;Choi, Kyungho
    • Journal of Environmental Health Sciences
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    • v.39 no.5
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    • pp.426-437
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    • 2013
  • Objective: Gotjawal refers to a special geographical designation found in Jeju Province, Korea, where vegetation forms over a rocky area. Due to the important ecological value of Gotjawal, international concern about such areas is growing. However, only limited information is available regarding environmental contamination of Gotjawal. This study was conducted in order to investigate the levels of contamination and associated ecotoxicological effects of surface water bodies in Gotjawal. Methods: Surface water samples were collected at three sampling sites in two Gotjawal areas and were analyzed for several pharmaceuticals and pesticides in consideration of the potential sources of contamination. The ecotoxicity of the samples was measured using water fleas (Daphnia magna and Moina macrocopa) and zebrafish (Danio rerio). In addition, effects on the gene transcription of zebrafish were investigated following exposure to the samples. Results: Nine pharmaceuticals were detected in the samples, but none of the target pesticides were detected. Following acute exposure to two surface water samples, the survival of waterfleas was significantly reduced, but reproduction was not affected. In zebrafish, time-to-hatch was delayed and fry survival was decreased in some samples. On the other hand, at the transcriptional level, there were no genes significantly influenced by exposure to the samples. Conclusion: This is the first study investigating environmental contamination in Gotjawal areas and associated ecotoxicities. Further studies are warranted to identify the cause of acute Daphnia toxicity and to determine potential consequences of longer-term exposure in Gotjawal areas.

Vulnerability Evaluation for Water Supply of Irrigation Facilities: Focusing on Dangjin-si, Yesan-gun, Cheongyang-gun, South Korea (밭관개 시설물의 용수공급에 대한 취약성 평가 - 당진시, 예산군, 청양군을 대상으로 -)

  • Shin, Hyung-Jin;Kwon, Hyung-Joong;Lee, Jae-Yeong;Lee, Jin-Heong;Park, Chan-Gi
    • Journal of The Korean Society of Agricultural Engineers
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    • v.60 no.6
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    • pp.33-42
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    • 2018
  • This study evaluated the vulnerability of irrigation water supplied to the crops. The target areas were selected as Dangjin-si, Yesan-gun, and Cheongyang-gun. The survey items of the climate exposure were annual precipitation and rainless days. The sensitivity survey items were cultivation area, groundwater level, evapotranspiration and groundwater consumption. The survey items of the adaptability were Number of groundwater well and Water supply ratio. The survey methods for these items were investigated in a variety of ways, including "National Climate Data Service System", "Korean Statistical Information Service", "National ground water monitoring network in korea annual report" and "Chungcheongnam-do Statistical Yearbook", "HOMWRS". Vulnerability assessment results were rated within the range of 0~100 points. The first grade was rated 0-25, the second grade 26-50, the third grade 51-75, and the fourth grade 76-100. And the lower the score, the lower the vulnerability. As a result, Cheongyang-gun showed a high vulnerability of over 50 points, Dangjin-si showed a low vulnerability rating of 31.20 points and a Yesan-gun of 36.00 points.

Experiments on the Submarine Cable Protection Methods Considering the Connection Type (체결형상을 고려한 해저케이블 보호공법에 관한 실험)

  • Yoon, Jae Seon;Ha, Taemin
    • Proceedings of the Korea Water Resources Association Conference
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    • 2017.05a
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    • pp.329-329
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    • 2017
  • In this study attempted to evaluate the stability of the protection methods by examining hydraulic characteristics of the area around the point in which marine cable protector is installed such as surf zone occurrence point of shore-end submarine cables suitable for coastal marine environmental conditions, flow rate t the tope of the protector and maximum wave height, and to provide basic data for the selection of the optimal protection method. In performing hydraulic model experiments, the topography of submarine cable installation location was reproduced in 2-D sectional channel, and models appropriate for experimental scale and similitude law were produced and installed for each condition of submarine cables and protectors. Since the topography and submarine cable protectors were reproduced and installed in 2-D sectional channel, the exact reproduction of surf and transformation in shallow water zone was possible, and thus the physical properties could be clearly analyzed. For stability review, an experiment to examine the stability was conducted using a wave maker with 50-year frequency design waves as target, and wave height and cycles were applied based on the approximate lowest low water level(Approx. L.L.W), which is the most dangerous in submarine cable protection methods. As for experimental time, typhoon passing time in summer (about 3 hours) was applied, and wave patterns and deviation ratio of the submarine cable protector were investigated after making irregular waves corresponding to design waves. In addition, current meter and wave height meter were installed at the installation location of the submarine cable protector, and the flow rates and wave height at the top of the protector were measured and analyzed to review hydraulic properties.

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The variation of channel flow through opening the gate at Shimgok-Cheon by using SMS program (SMS를 이용한 인천 심곡천 하구 수문개방에 따른 하천흐름변화 분석)

  • Kim, Chanyeong;Jeong Gwansoo;Kim, Youngkyu
    • Journal of Korea Water Resources Association
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    • v.57 no.6
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    • pp.385-392
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    • 2024
  • By installing the gate at the estuary to prevent the inflow of seawater into the river, it was prevented the inflow of seawater into the river, but as a result, the velocity of the river was rapidly decreased, turning it into a river with almost stoped flow. Since a river must have flow to maintain its function, in this study, it examined improving the flow of the river through the operation of a gate in Simgok-cheon where is a river that has been closed by a hydrological system at the estuary and almost stoped flow. It was considered that if the gate are operated according to the tide level, it could be changed into a river through which water flows by raising it to 0.49 m/s, which is about 10 times faster than the current slow flow rate of 0.05 m/s while maintaining the highest or lowest target elevation.

A Study on Flood Storage Plans of Farmlands for Extreme Flood Reduction (극한홍수 저감을 위한 농경지의 저류지화 방안 연구)

  • Kang, Hyeong-Sik;Cho, Seong-Yun;Song, Young-Il
    • Journal of Korea Water Resources Association
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    • v.44 no.10
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    • pp.787-795
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    • 2011
  • Extreme water events such as heavy rainfalls due to recent climate change are continually increasing and their scale has also shown an increasing trend. To overcome these natural disasters, this policy study suggests securing lateral river space as an effective method for extreme flood. To support the importance of restoration and expansion of lateral river space, Gumi upstream region of the Nakdong River basin was chosen as a target area and flood reduction analysis of the washland by using LISFLOOD model have been examined. The 500-year frequency flood was simulated for the estimation of possibly occurable flood level and it turns out that the secured lateral river space on the selected site effectively lowers about 0.53 m flood level and reduces the flood damage of the city on the lower reaches of the river. In addition, based on this result, multilateral river space securing plans were compared, and conservation easement and natural disaster insurance were suggested for sustainable and cost-effective alternatives. The costs of land purchase and conservation easement for securing the river space were also compared.

A Study on the Application of a Turbidity Reduction System for the Utilization of Thermal Wastewater in High Turbidity Zones (고탁도 해역의 온배수 활용을 위한 탁도저감시스템 적용에 대한 연구)

  • Ha, Shin-Young;Oh, Cheol;Gug, Seung-Gi
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.24 no.7
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    • pp.916-922
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    • 2018
  • Recently, power plant effluent condensers received a Renewable Energy Certificate as components of hydrothermal energy (weighted 1.5 times) as one target item of the Renewable Portfolio Standard (RPS) policy. Accordingly, more attention is being paid to the value of thermal wastewater as a heat source. However, for utilization of thermal wastewater from power plants in high-turbidity areas like the West Sea of Korea, a turbidity reducing system is required to reduce system contamination. In this study, an experimental test was performed over a month on thermal wastewater from power plants located in the West Sea of Korea. It was found that water turbidity was reduced by more than 80 % and that the concentration of organic materials and nutrient salts was partially reduced due to the reduction of floating/drifting materials. To conduct a comparative analysis of the level of contamination of the heat exchanger when thermal wastewater flows in through a turbidity reducing system versus when the condenser effluent flows in directly without passing through the turbidity system, we disassembled and analyzed heat exchangers operated for 30 days. As a result, it was found that the heat exchanger without a turbidity reducing system had a higher level of contamination. Main contaminants (scale) that flowed in to the heat exchanger included minerals such as $SiO_2$, $Na(Si_3Al)O_8$, $CaCO_3$ and NaCl. It was estimated that marine sediment soil flowed in to the heat exchanger because of the high level of turbidity in the water-intake areas.

Intensity Modulated Radiation Therapy Commissioning and Quality Assurance: Implementation of AAPM TG119 (세기조절방사선치료(IMRT)의 Commissioning 및 정도관리: AAPM TG119 적용)

  • Ahn, Woo-Sang;Cho, Byung-Chul
    • Progress in Medical Physics
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    • v.22 no.2
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    • pp.99-105
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    • 2011
  • The purpose of this study is to evaluate the accuracy of IMRT in our clinic from based on TG119 procedure and establish action level. Five IMRT test cases were described in TG119: multi-target, head&neck, prostate, and two C-shapes (easy&hard). There were used and delivered to water-equivalent solid phantom for IMRT. Absolute dose for points in target and OAR was measured by using an ion chamber (CC13, IBA). EBT2 film was utilized to compare the measured two-dimensional dose distribution with the calculated one by treatment planning system. All collected data were analyzed using the TG119 specifications to determine the confidence limit. The mean of relative error (%) between measured and calculated value was $1.2{\pm}1.1%$ and $1.2{\pm}0.7%$ for target and OAR, respectively. The resulting confidence limits were 3.4% and 2.6%. In EBT2 film dosimetry, the average percentage of points passing the gamma criteria (3%/3 mm) was $97.7{\pm}0.8%$. Confidence limit values determined by EBT2 film analysis was 3.9%. This study has focused on IMRT commissioning and quality assurance based on TG119 guideline. It is concluded that action level were ${\pm}4%$ and ${\pm}3%$ for target and OAR and 97% for film measurement, respectively. It is expected that TG119-based procedure can be used as reference to evaluate the accuracy of IMRT for each institution.

Unsteady Flow Model Including a Dam Operation Rule for Flood Control as Internal Boundary Condition (홍수시 댐 운영방안을 내부 경계조건으로 포함하는 부정류 계산모형)

  • Yu, Myoung-Kwan;Jun, Kyung-Soo
    • Journal of Korea Water Resources Association
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    • v.37 no.12
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    • pp.1043-1054
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    • 2004
  • An unsteady flow model for channel network including various internal boundaries if developed. It is a multiply-connected network model based on the Preissmann's four-point scheme and the Newton-Raphson method, where looped double-sweep algorithm is used. The model is capable of simulating flow through hydraulic structures such as dams and submerged weirs. It can also simulate automatic reservoir operation method (Auto ROM) for flood control, that is to maintain a target water level, by incorporating the strategy to the unsteady flow model as internal boundary condition. The model is applied to the Han River system that includes the downstream reaches of Choongju dam and Hwacheon dam as well as the downstream reach of the Paldang dam. Roughness coefficient for the downstream reach of Choongju dam is estimated. Automatic ROM is presumed for the Paldang, Chungpyung, Euiam, and Choonchun dams. The model is tested using historical flood records, and the flood control strategy is successfully simulated.