• Parasites, Hosts and Diseases
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• 제44권2호
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• pp.127-131
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• 2006

The furcocercus cercariae of Neodiplostomum seoulense (Digenea: Neodiplostomidae) penetrate the skins of tadpoles and shed their tails. The speculated mechanism of this tail loss was physical efforts required to produce a vigorous zigzag motion during skin penetration; no other mechanism has been proposed. We examined the relationship between the host serum and cercarial tail loss. Cercariae of N. seoulense were collected from experimentally infected Segmentina hemisphaerula, and lots of 300 cercariae were cultured in medium 199 contained several types of sera. Cercarial tail degradation was induced in all media, but all the cercariae cultured except those cultured in media containing fetal bovine serum (FBS) died within 48 hr. After 72 hr cultivation in media containing FBS, cercarial tail degradation was induced in 67.0%; in continuous cultivation 13.3% of larvae survived for 7 days. Tail degradation did not occur in the absence of serum and when serum was heat inactivated at $56^{\circ}C$ for 30 min. The addition of 20 mM ethylenediaminetetraacetic acid (EDTA) blocked cercarial tail degradation completely. Moreover, the addition of 20 mM $MgCl_2$ restored tail degradation blocked by EDTA. These results suggest that the alternative complement pathway is related with the N. seoulense cercarial tail degradation induced by serum.

• 미생물학회지
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• 제16권2호
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• pp.79-89
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• 1978

The RK-temperate phage which infected with Bacillus cereus was isolated and the characters were investigated. The induction of RK-temperate phage from host bacterium attained by ultraviolet light irradiation (15W, 30cm, 30-120sec) and mitomycin C treatment (0.2-2 ug/ml). The host range of RK-temperate phage was not revealed with lysogenic and related strains of B. cereus. But B. cereus(PS) 352 which obtained by N-nitrosoguanidine treatment(1,000.$\mu$g/ml) to phage infected with host bacteria was sensitive bacteria of RK-temperate phage. RK-temperate phage was stabilized at the condition of nutrient broth (pH 7-8), Tris-buffer (pH 7-8) and ammonium buffer (pH 8-9) and Sorensen's phosphate buffer (pH 6-7), but unstabilized at other salt solutions and pH range. Also, thermostability was to 45.deg.C but unstabilized at above 50.deg.C. At RK-temperate phage, the measurment values of head, neck, mid tail and end tail were 59nm, 9*16nm, 10*189nm, and 10*14nm respectively. The morphology of head was regular polyhedron, and the end tail was coneate form. On the one hand, the number of capsid protein layer of tail were consist of 4, 35, and 1 at neck, mid tail, and end tail, respectively. RK-temperate phage was identified with DNA phage and G+C contents were 38.63. The latent time of RK-temperate phage was 30 minutes and the burst size was 70-80. And the host bacteria was lysed in case of multi-infection, above moi 1.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2023년도 춘계학술발표대회
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• pp.585-587
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• 2023

Long-tailed datasets have an imbalanced distribution because they consist of a different number of data samples for each class. However, there are problems of the performance degradation in tail-classes and class-accuracy imbalance for all classes. To address these problems, this paper suggests a learning method for training of long-tailed dataset. The proposed method uses and combines two methods; one is a resampling method to generate a uniform mini-batch to prevent the performance degradation in tail-classes, and the other is a reweighting method to address the accuracy imbalance problem. The purpose of our proposed method is to train the learning models to have uniform accuracy for each class in a long-tailed dataset.

• International Journal of Aeronautical and Space Sciences
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• 제10권2호
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• pp.117-124
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• 2009

In the environment where various and complicated threat signals exist, RWR (Radar Warning Receiver), which can warn pilot of the existence of threats, has long been a necessary electronic warfare (EW) system to improve survivability of aircraft. The angle of arrival (AOA) information, the most reliable sorting parameter in the RWR, is measured by means of four-quadrant amplitude comparison direction finding (DF) technique. Each of four antennas (usually spiral antenna) of DF unit covers one of four quadrant zones, with 90 degrees apart with nearby antenna. According to the location of antenna installed in helicopter, RWR is subject to signal loss and interference by helicopter body and structures including tail bumper, rotor blade, and so on, causing a difficulty of detecting hostile emitters. In this paper, the performance degradation caused by signal interference by tail rotor blades has been estimated by measuring amplitude video signals into which RWR converts RF signals in case a part of antenna is screened by real tail rotor blade in anechoic chamber. The results show that corruption of pulse amplitude (PA) is main cause of DF error. We have proposed two algorithms for resolving the interference by tail rotor blades as below: First, expand the AOA group range for pulse grouping at the first signal analysis phase. Second, merge each of pulse trains with the other, that signal parameter except PRI and AOA is similar, after the first signal analysis phase. The presented method makes it possible to use RWR by reducing interference caused by blade screening in case antenna is screened by tail rotor blades.

• Nuclear Engineering and Technology
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• 제55권12호
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• pp.4350-4356
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• 2023

Radiation detection systems working at high count rates suffer from the overlapping of their output electric pulses, known as pulse pile-up phenomenon, resulting in spectrum distortion and degradation of the energy resolution. Pulse tail extrapolation is a pile-up correction method which tries to restore the shifted baseline of a piled-up pulse by extrapolating the overlapped part of its preceding pulse. This needs a mathematical model which is almost always nonlinear, fitted usually by a nonlinear least squares (NLS) technique. NLS is an iterative, potentially time-consuming method. The main idea of the present study is to replace the NLS technique by an integration-based non-iterative method (NIM) for pulse tail extrapolation by an exponential model. The idea of linear extrapolation, as another non-iterative method, is also investigated. Analysis of experimental data of a NaI(Tl) radiation detector shows that the proposed non-iterative method is able to provide a corrected spectrum quite similar with the NLS method, with a dramatically reduced computation time and complexity of the algorithm. The linear extrapolation approach suffers from a poor energy resolution and throughput rate in comparison with NIM and NLS techniques, but provides the shortest computation time.

• 정보과학회 논문지
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• 제44권8호
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• pp.767-773
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• 2017

클라우드 데이터베이스와 같은 분산 시스템 환경에서는 균일한 서비스 품질을 보장하기 위해 꼬리 응답시간을 짧게 유지하는 것이 중요하다. 본 논문에서는 카산드라 데이터베이스를 대상으로, 긴 꼬리 응답시간에 해당하는 지연이 메모리 공간 부족으로 인해 발생한다는 것을 보이며, 이러한 지연이 메모리 공간 확보를 위해 버퍼에 저장된 데이터를 저장장치에 완전히 내려쓸 때까지 카산드라가 사용자의 요청을 받지 않기 때문임을 밝힌다. 버퍼에 저장된 데이터를 내려쓰는데 걸리는 시간은 저장장치 성능에 따라 결정되므로 SSD의 가바지 컬렉션으로 인한 성능 저하가 꼬리 응답시간을 더 길게 만들고 있음을 관찰하였다. 우리는 자바가상기계에서의 가비지 컬렉션과 SSD에서의 가비지 컬렉션을 함께 수행하여 SSD의 가비지 컬렉션 비용을 숨기는, SyncGC 기법을 제안한다. 실험 결과, SyncGC 기법을 통해 꼬리 응답시간인 $99.9^{th}$와 $99.9^{th}-percentile$을 각각 31%, 36% 줄일 수 있었다.

• Applied Microscopy
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• 제39권2호
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• pp.107-115
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• 2009

참개구리(Rana nigromaculata) 꼬리 퇴화과정에 따른 피부 상피조직의 분화와 세포자멸사에 의해 초래된 상피의 미세구조적 변화를 TUNEL 조직화학적 염색 및 고배율의 투과전자현미경 관찰을 통해 확인하였다. 꼬리의 퇴화가 시작되는 Shumway 31단계의 올챙이 피부에 발달되어 있던 점액층은 발생 32 단계를 거쳐 사라지고 상피는 비후되어 꼬리의 퇴화가 완료되는 발생 33 단계에 도달하면 성체인 개구리의 다층상피로 전환되었다. TUNEL 염색결과, 꼬리 퇴화과정중 apoptosis 세포의 출현은 원위부(distal region)의 꼬리에서 시작되어 몸통 쪽의 근위부(proximal region)로 이행되었고, 동일 상피층에서는 내강부로부터 기저부로 전이되는 특성을 보였다. 투과 전자현미경 관찰 결과, 세포자멸사에 의한 초기의 변형은 인접세포와의 세포간극이 사라지고 밀착된 후, 핵의 모양이 불규칙해지고 염색질이 응축되었다. 이어서 세포질에 다수의 자유 리보솜이 나타나고, 핵의 분절이 일어난 후, apoptotic body가 출현하며, 이들은 최종적으로 라멜라 구조를 지닌 잔여소체(residual body)를 형성하였다

• 한국음향학회지
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• 제25권7호
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• pp.312-318
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• 2006

기존의 립싱크 시스템은 음소 분할 후, 각각의 음소를 인식하는 2단계의 과정을 거쳤다. 하지만, 정확한 음소 분할의 부재와 음성이 끊긴 분할 된 음소로 이루어진 훈련 데이터들은 시스템의 전체 성능을 크게 떨어뜨렸다. 이런 문제를 해결하기 위해 Head-Body-Tail (HBT) 모델을 이용한 단모음 연속어 인식 기술을 제안한다. 주로 소규모 어휘를 다루는데 적합한 HBT 모델은 Head 와 Tail 부분에 문맥 종속 정보를 포함하여 앞 뒤 문맥에 따른 조음효과를 최대한 반영한다. 또한, 7개의 단모음을 입모양이 비슷한 세 개의 클래스로 분류하여, 클래스에 종속적인 코드북 3개를 가진 반연속HMM (Hidden Markov Model)을 적용하여 시스템을 최적화하고, 변이 부분이 큰 단어의 처음과 끝은 연속HMM의 8 믹스쳐 가우시안 구조를 사용하여 모델링하였다. 제안한 방법은 HBT구조의 연속HW과 대등한 성능을 보이지만, 파라미터 수는 33.92% 감소하였다. 파라미터 감소는 계산 양을 줄여주므로, 시스템이 실시간으로 동작 가능하게 한다.

• Transactions on Electrical and Electronic Materials
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• 제6권1호
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• pp.1-5
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• 2005

Continued scaling of MOS devices requires the formation of the ultra shallow and very heavily doped junction. The simulation and experiment results show that the degradation of pMOS performance in logic and SRAM pMOS devices due to the excessive diffusion of the tail and a large amount of dose loss in the extension region. This problem comes from the high-temperature long-time deposition process for forming the spacer and the presence of fluorine which diffuses quickly to the $Si/SiO_{2}$ interface with boron pairing. We have studied the method to improve the pMOS performance that includes the low-energy boron implantation, spike annealing and device structure design using TCAD simulation.

• BMB Reports
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• 제41권12호
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• pp.858-862
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• 2008

Membrane-type 1 matrix metalloproteinase (MT1-MMP) is a zinc-dependent proteinase found in cholesterol-rich lipid rafts on the plasma membrane. MT1-MMP hydrolyzes extracellular matrix (ECM) proteins, activates pro-matrix metalloproteinase-2 (proMMP-2) and plays an important role in ECM remodeling, cancer cell migration and metastasis. The role of caveolin-1, an integral protein of caveolae, in the activation of MT1-MMP remains largely unknown. Here, we show that the expression of caveolin-1 attenuates the activation of proMMP-2, reduces proteolytic cleavage of ECM and inhibits cell migration. We utilized the cytoplasmic tail domain deletion (${\Delta}CT$) or the E240A mutant of MT1-MMP. Co-expression of caveolin-1 with the wild-type or the ${\Delta}CT$ MT1-MMP decreased the proMMP-2 activation and inhibited collagen degradation and cell migration. Caveolin-1 had no effect on the catalytically inert E240A MT1-MMP. Our findings suggest that caveolin-1 is essential in the down-regulation of MT1-MMP activity by promoting internalization from the cell surface.