• Parasites, Hosts and Diseases
• /
• v.44 no.2 s.138
• /
• pp.127-131
• /
• 2006

The furcocercus cercariae of Neodiplostomum seoulense (Digenea: Neodiplostomidae) penetrate the skins of tadpoles and shed their tails. The speculated mechanism of this tail loss was physical efforts required to produce a vigorous zigzag motion during skin penetration; no other mechanism has been proposed. We examined the relationship between the host serum and cercarial tail loss. Cercariae of N. seoulense were collected from experimentally infected Segmentina hemisphaerula, and lots of 300 cercariae were cultured in medium 199 contained several types of sera. Cercarial tail degradation was induced in all media, but all the cercariae cultured except those cultured in media containing fetal bovine serum (FBS) died within 48 hr. After 72 hr cultivation in media containing FBS, cercarial tail degradation was induced in 67.0%; in continuous cultivation 13.3% of larvae survived for 7 days. Tail degradation did not occur in the absence of serum and when serum was heat inactivated at $56^{\circ}C$ for 30 min. The addition of 20 mM ethylenediaminetetraacetic acid (EDTA) blocked cercarial tail degradation completely. Moreover, the addition of 20 mM $MgCl_2$ restored tail degradation blocked by EDTA. These results suggest that the alternative complement pathway is related with the N. seoulense cercarial tail degradation induced by serum.

• Korean Journal of Microbiology
• /
• v.16 no.2
• /
• pp.79-89
• /
• 1978

The RK-temperate phage which infected with Bacillus cereus was isolated and the characters were investigated. The induction of RK-temperate phage from host bacterium attained by ultraviolet light irradiation (15W, 30cm, 30-120sec) and mitomycin C treatment (0.2-2 ug/ml). The host range of RK-temperate phage was not revealed with lysogenic and related strains of B. cereus. But B. cereus(PS) 352 which obtained by N-nitrosoguanidine treatment(1,000.$\mu$g/ml) to phage infected with host bacteria was sensitive bacteria of RK-temperate phage. RK-temperate phage was stabilized at the condition of nutrient broth (pH 7-8), Tris-buffer (pH 7-8) and ammonium buffer (pH 8-9) and Sorensen's phosphate buffer (pH 6-7), but unstabilized at other salt solutions and pH range. Also, thermostability was to 45.deg.C but unstabilized at above 50.deg.C. At RK-temperate phage, the measurment values of head, neck, mid tail and end tail were 59nm, 9*16nm, 10*189nm, and 10*14nm respectively. The morphology of head was regular polyhedron, and the end tail was coneate form. On the one hand, the number of capsid protein layer of tail were consist of 4, 35, and 1 at neck, mid tail, and end tail, respectively. RK-temperate phage was identified with DNA phage and G+C contents were 38.63. The latent time of RK-temperate phage was 30 minutes and the burst size was 70-80. And the host bacteria was lysed in case of multi-infection, above moi 1.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2023.05a
• /
• pp.585-587
• /
• 2023

Long-tailed datasets have an imbalanced distribution because they consist of a different number of data samples for each class. However, there are problems of the performance degradation in tail-classes and class-accuracy imbalance for all classes. To address these problems, this paper suggests a learning method for training of long-tailed dataset. The proposed method uses and combines two methods; one is a resampling method to generate a uniform mini-batch to prevent the performance degradation in tail-classes, and the other is a reweighting method to address the accuracy imbalance problem. The purpose of our proposed method is to train the learning models to have uniform accuracy for each class in a long-tailed dataset.

• International Journal of Aeronautical and Space Sciences
• /
• v.10 no.2
• /
• pp.117-124
• /
• 2009

In the environment where various and complicated threat signals exist, RWR (Radar Warning Receiver), which can warn pilot of the existence of threats, has long been a necessary electronic warfare (EW) system to improve survivability of aircraft. The angle of arrival (AOA) information, the most reliable sorting parameter in the RWR, is measured by means of four-quadrant amplitude comparison direction finding (DF) technique. Each of four antennas (usually spiral antenna) of DF unit covers one of four quadrant zones, with 90 degrees apart with nearby antenna. According to the location of antenna installed in helicopter, RWR is subject to signal loss and interference by helicopter body and structures including tail bumper, rotor blade, and so on, causing a difficulty of detecting hostile emitters. In this paper, the performance degradation caused by signal interference by tail rotor blades has been estimated by measuring amplitude video signals into which RWR converts RF signals in case a part of antenna is screened by real tail rotor blade in anechoic chamber. The results show that corruption of pulse amplitude (PA) is main cause of DF error. We have proposed two algorithms for resolving the interference by tail rotor blades as below: First, expand the AOA group range for pulse grouping at the first signal analysis phase. Second, merge each of pulse trains with the other, that signal parameter except PRI and AOA is similar, after the first signal analysis phase. The presented method makes it possible to use RWR by reducing interference caused by blade screening in case antenna is screened by tail rotor blades.

• Nuclear Engineering and Technology
• /
• v.55 no.12
• /
• pp.4350-4356
• /
• 2023

Radiation detection systems working at high count rates suffer from the overlapping of their output electric pulses, known as pulse pile-up phenomenon, resulting in spectrum distortion and degradation of the energy resolution. Pulse tail extrapolation is a pile-up correction method which tries to restore the shifted baseline of a piled-up pulse by extrapolating the overlapped part of its preceding pulse. This needs a mathematical model which is almost always nonlinear, fitted usually by a nonlinear least squares (NLS) technique. NLS is an iterative, potentially time-consuming method. The main idea of the present study is to replace the NLS technique by an integration-based non-iterative method (NIM) for pulse tail extrapolation by an exponential model. The idea of linear extrapolation, as another non-iterative method, is also investigated. Analysis of experimental data of a NaI(Tl) radiation detector shows that the proposed non-iterative method is able to provide a corrected spectrum quite similar with the NLS method, with a dramatically reduced computation time and complexity of the algorithm. The linear extrapolation approach suffers from a poor energy resolution and throughput rate in comparison with NIM and NLS techniques, but provides the shortest computation time.

• Journal of KIISE
• /
• v.44 no.8
• /
• pp.767-773
• /
• 2017

In a distributed system environment, such as a cloud database, the tail latency needs to be kept short to ensure uniform quality of service. In this paper, through experiments on a Cassandra database, we show that long tail latency is caused by a lack of memory space because the database cannot receive any request until free space is reclaimed by writing the buffered data to the storage device. We observed that, since the performance of the storage device determines the amount of time required for writing the buffered data, the performance degradation of Solid State Drive (SSD) due to garbage collection results in a longer tail latency. We propose a garbage collection synchronization technique, called SyncGC, that simultaneously performs garbage collection in the java virtual machine and in the garbage collection in SSD concurrently, thus hiding garbage collection overheads in the SSD. Our evaluations on real SSDs show that SyncGC reduces the tail latency of $99.9^{th}$ and, $99.9^{th}-percentile$ by 31% and 36%, respectively.

• Applied Microscopy
• /
• v.39 no.2
• /
• pp.107-115
• /
• 2009

The programed cell death of the cutaneous epithelial tissue during tail regression stages in anuran tadpoles of the blackspotted frog, Rana nigromaculata were visualized by the histochemical and transmission electron microscopic techniques. Metamorphotic changes in the tail regression during the period of the Shumway stage number 31 to 33 are characterized by the disappearance of mucous layer and formation of compound epithelium through cutaneous thickening. Following the TUNEL (terminal deoxynucleotidyl transferase-mediated biotinylated d-uridine triphosphate nick end labeling) staining technique, the apoptotic cells were detected at the distal region of the tail skin initially, but they can be seen at the proximal region according to their following development. It has been also revealed that the number of the TUNEL-positive cells gradually increased from apical to basal direction of the epithelial layers during the tail regressing stages. Following the TEM observation, the early apoptotic cells shown in the epithelium demonstrated condensation and margination of the chromatin material at the nuclear periphery. Another epithelial apoptotic cells were shown nuclear fragmentation, membrane blebbing and cytoplasmic condensation. Following the process of the apoptotic degradation, well preserved organelles and nuclear fragments can be identified in the cytoplasm of lysosome-rich cells, however they soon reduced to lysosomal residual bodies through the progressive degradation.

• The Journal of the Acoustical Society of Korea
• /
• v.25 no.7
• /
• pp.312-318
• /
• 2006

The conventional lip-synch system has a two-step process, speech segmentation and recognition. However, the difficulty of speech segmentation procedure and the inaccuracy of training data set due to the segmentation lead to a significant Performance degradation in the system. To cope with that, the connected vowel recognition method using Head-Body-Tail (HBT) model is proposed. The HBT model which is appropriate for handling relatively small sized vocabulary tasks reflects co-articulation effect efficiently. Moreover the 7 vowels are merged into 3 classes having similar lip shape while the system is optimized by employing a class dependent SCHMM structure. Additionally in both end sides of each word which has large variations, 8 components Gaussian mixture model is directly used to improve the ability of representation. Though the proposed method reveals similar performance with respect to the CHMM based on the HBT structure. the number of parameters is reduced by 33.92%. This reduction makes it a computationally efficient method enabling real time operation.

• Transactions on Electrical and Electronic Materials
• /
• v.6 no.1
• /
• pp.1-5
• /
• 2005

Continued scaling of MOS devices requires the formation of the ultra shallow and very heavily doped junction. The simulation and experiment results show that the degradation of pMOS performance in logic and SRAM pMOS devices due to the excessive diffusion of the tail and a large amount of dose loss in the extension region. This problem comes from the high-temperature long-time deposition process for forming the spacer and the presence of fluorine which diffuses quickly to the $Si/SiO_{2}$ interface with boron pairing. We have studied the method to improve the pMOS performance that includes the low-energy boron implantation, spike annealing and device structure design using TCAD simulation.

• BMB Reports
• /
• v.41 no.12
• /
• pp.858-862
• /
• 2008

Membrane-type 1 matrix metalloproteinase (MT1-MMP) is a zinc-dependent proteinase found in cholesterol-rich lipid rafts on the plasma membrane. MT1-MMP hydrolyzes extracellular matrix (ECM) proteins, activates pro-matrix metalloproteinase-2 (proMMP-2) and plays an important role in ECM remodeling, cancer cell migration and metastasis. The role of caveolin-1, an integral protein of caveolae, in the activation of MT1-MMP remains largely unknown. Here, we show that the expression of caveolin-1 attenuates the activation of proMMP-2, reduces proteolytic cleavage of ECM and inhibits cell migration. We utilized the cytoplasmic tail domain deletion (${\Delta}CT$) or the E240A mutant of MT1-MMP. Co-expression of caveolin-1 with the wild-type or the ${\Delta}CT$ MT1-MMP decreased the proMMP-2 activation and inhibited collagen degradation and cell migration. Caveolin-1 had no effect on the catalytically inert E240A MT1-MMP. Our findings suggest that caveolin-1 is essential in the down-regulation of MT1-MMP activity by promoting internalization from the cell surface.