• 대한간호학회지
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• 제41권2호
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• pp.165-174
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• 2011

Purpose: This study was done to identify effects of a fall prevention program on physical fitness and psychological functions in community dwelling elders. Methods: A quasi-experimental study was carried out with a nonequivalent control group pre & post-test design. The program, which included exercises and education, consisted of a 12-week group program and an 8-week self-management program using a health calendar. An experimental group (32) and a control group (21) participated. Results: There were significant differences in SPPB (t=-3.92, p<.001), TUG test (t=4.94, p<.001), standing with right leg (t= -3.60, p=.001), standing with left leg (t=-3.74, p<.001), front and rear maximum step length test (t=-4.34, p<.001), right-left maximum step length test (t=-2.65, p=.011), and fall efficacy (t=-2.42, p=.019). Fall efficacy, fear of falling and depression showed significant differences following the 12-week exercise program and 8-week self-management program in the experimental group. Conclusion: Study findings indicate that the fall prevention program is an effective nursing intervention to enhance physical fitness and psychological functions for elders. Using a health calendar, the self-management program was more effective for psychological functions compared to only the group program. Therefore, health providers should develop diversified fall prevention programs which include motivation plans to encourage clients in participating.

• 약학회지
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• 제51권6호
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• pp.508-516
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• 2007

Thymus magnus is an endemic (Ulleung Island) species in Korea. This plant is used as diaphoretics and carminatives in traditional medicine. In the literature, few scientific assays were realized on this species, such as antibiotic (Streptococcus pneumoniae, Staphylococcus aureus, Salmonella enteritidis, and S. typhimurium) and antifungal activities. In order to clarify whether essential oil of T. magnus have pharmacological effects, anti-inflammatory, sedative, anti-depressant, analgesic, and sleep-prolonged effects were investigated using animal models. From this study, the following conclusions were attained; 1) Essential oil of T. magnus did not show any acute toxicity on mice when orally administered at the dose of 2-3 g/kg body weight. 2) Essential oil of T. magnus possessed strong anti-inflammatory activity, similar to that of a positive control prednisolone. 3) Essential oil of T. magnus had excellent analgesic activity, comparable to that of aspirin. 4) The essential oil of T. magnus possessed strong sleep-prolonged effect on pentobarbital induced-sleep test in mice model. 5) In the hot plate test, the essential oil of T. magnus had moderate effect. 6) And the essential oil of T. magnus had no significant effects in forced-swimming test and open-field test.

• 대한수의학회지
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• 제37권3호
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• pp.613-618
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• 1997

곰팡이에 오염된 저질사료에서 T-2 독소의 존재확인 및 양을 측정하기 위한 Direct Competitive Enzyme Linked Immunosorbent Assay(ELISA)의 Kits를 개발하기 위하여 T-2HS, T-2HS-BSA, T-2HS-HRP 및 T-2 단크론 항체 동을 개발하고저 연구하여 좋은 결과를 얻었다. 분말 옥수수내에 인위적으로 혼합된 T-2 독소의 평균회수율은 83%이었으며, T-2 독소의 추출가능범위는 60ng에서 $6{\mu}g$이었다. 분말옥수수에서 인위적으로 혼합된 T-2 독소의 회수결과에 의하면 이 연구는 T-2 독소의 존재를 확인하기에 적합하고, T-2 독소의 양을 측정하기 위한각종 ELISA Kits 제조의 기틀이 마련되었다.

• Biomolecules & Therapeutics
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• 제15권2호
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• pp.118-122
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• 2007

This study was performed to evaluate the bioequivalency between the Osmetone$^{TM}$ Tablet (Myeongmoon Pharm. Co., Ltd.) as a test formulation and the Relafen$^{TM}$ Tablet (Handok Pharm. Co., Ltd.) as a reference formulation. Twenty-four healthy male volunteers were administered the formulations by the randomized Latin square crossover design, and the plasma samples were determined by a high performance liquid chromatography (HPLC) with Ultra-Violet (UV) detector. AUC$_t$, C$_{max}$ and T$_{max}$ were obtained from the time-plasma concentration curves, and log-transformed AUC$_t$ and C$_{max}$ and log-untransformed T$_{max}$ values for two formulations were compared by statistical tests and analysis of variation. AUC$_t$ was determined to be 897.8${\pm}$431.1 ug.hr/ml for the reference formulation and 902.3${\pm}$408.4 ug.hr/ml for the test formulation. The mean values of C$_{max}$ for the reference and test formulations were 24.2${\pm}$8.9 and 24.0${\pm}$9.5 ug/ml, respectively. The AUC$_t$ and C$_{max}$ ratios of the reference Relafen$^{TM}$ Tablet to the test Osmetone$^{TM}$ Tablet were +5.01% and -0.83%, respectively, showing that the mean differences were satisfied the acceptance criteria within 20%. The results from analysis of variance for logtransformed AUC$_t$ and C$_{max}$ indicated that sequence effects between groups were not exerted and 90% confidence limits of the mean differences for AUC$_t$ and C$_{max}$ were located in ranges from log 0.80 to log 1.25, satisfying the acceptance criteria of the KFDA bioequivalence. The Osmetone$^{TM}$ Tablet as the test formulation was considered to be bioequivalant to the Relafen$^{TM}$ Tablet used as its reference formulation, based on AUC$_t$ and C$_{max}$ values.

• 여성건강간호학회지
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• 제5권1호
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• pp.51-64
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• 1999

Dance movement program. Psychological wellbeing, Middle aged women, Wellbeing with depression tendency, 율동적 동작 프로그램, 우울성향 중년여성 %600an This study was designed to confirm the effects of the Dance Movement Program on psychological health in middle-age women with depression tendency. 67 women with mile to moderate depression scoring between 16-25 were selected among 235 responded to CES-D (Radloff, 1977, Cho and Kim, 1993). The 46 volunteered to participate in the study were assigned the control. 7 attritions occurred during the course of the experiment leaving thirty-nine subject : nineteen experimental and twenty control, for the final analysis. Research subjects revealed to be homogenous demographically and by health-related variables. The 50-minute Dance Movement Program was performed by the experimental group 3 times a week for eight weeks, from October 6 to November 29, 1997. Depression, life satisfaction, self efficacy were measured before and after the course of Dance Movement Program. Plasma serotonin was measured to identify its relationship with depression, Homogeneity tests revealed satisfactory level on relevant research variables. Data were analyzed by $x^2$-test, paired and unpaired t-tests. The results are as follows : 1) The hypothesis that depresson score of experimental group will decreased than control group was supported by t-test(t=2.20, P=.0021) 2) The hypothesis that life satisfaction score of experimental group will increased than control group was supported by t-test(t=1.42, P=.0049). 3) The hypothesis that self-efficacy score of experimental group will increased than control group was not supported by t-test(t=6.20, P=.0616). 4) The hypothesis that level of plasma serotonin will increased than control group was not supported by t-test(t=1.88, P=.0524) Thus, the effects of the Dance Movement Program for the improvement of psychological health gram for the improvement of psychological health for the middle-aged women with depression tendency are scientifically confirmed by this study.

• Biomolecules & Therapeutics
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• 제14권1호
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• pp.50-55
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• 2006

The objective of the study was to evaluate the bioequivalency between the $Rozid^{TM}$ Tablet (Ilhwa Pharm. Co., Ltd.) as a test formulation and the $Rulid^{TM}$ Tablet (Handok Pharm. Co., Ltd) as a reference formulation. Twenty-four healthy male volunteers were administered the formulations by the randomized Latin square crossover design, and the plasma samples were determined by a high performance liquid chromatography (HPLC) with fluorescence detector. $AUC_t,\;C_{max}\;and\;T_{max}$ were obtained from the time-plasma concentration curves, and log-transformed $AUC_t\;and\;C_{max}$ and log-untransformed $T_{max}$ values for two formulations were compared by statistical tests and analysis of variation. $AUC_t$ was determined to be $63.30{\pm}25.57{\mu}g.hr/ml$ for the test formulation and $64.02{\pm}29.27mg.hr/ml$ for the reference formulation. The mean values of $C_{max}$ for the test and reference formulations were $5.07{\pm}2.14\;and\;5.53{\pm}2.60{\mu}g/ml$, respectively. The $AUC_t,\;and\;C_{max}$ ratios of the test $Rozid^{TM}$ Tablet to the reference $Rulid^{TM}$ Tablet were -1.12% and -8.32%, respectively, showing that the mean differences were satisfied the acceptance criteria within 20%. The results from analysis of variance for log-transformed $AUC_t,\;and\;C_{max}$ indicated that sequence effects between groups were not exerted and 90% confidence limits of the mean differences for $AUC_t,\;and\;C_{max}$ were located in ranges from log 0.80 and log 1.25, satisfying the acceptance criteria of the KFDA bioequivalence. The RozidTM Tablet as the test formulation was considered to be bioequivalent to the RulidTM Tablet used as its reference formulation, based on $AUC_t,\;and\;C_{max}$ values.

• 한국추진공학회지
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• 제15권4호
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• pp.79-84
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• 2011

본 논문은 한국형 기동헬기(수리온)에 탑재되는 T700/701K 터보 샤프트 엔진의 개발 현황을 기술한다. T700/701K 엔진은 군용 헬기엔진으로 널리 사용되고 있는 GE사의 T700엔진을 후방 구동형으로 최초 개조 개발한 엔진이다. 주요 개발 내용은 크게 엔진 장착 요구조건에 의한 후방 구동형 개조, 동력터빈 성능 향상 및 엔진 운전 신뢰성 향상을 위한 2채널 FADEC 시스템 적용 등이다. 2006년 6월 사업이 착수되어 개발 및 인증시험용 엔진의 초도 운전이 2008년에 성공적으로 수행되었으며 예비비행 정격시험 수행을 통해 2010년 3월에 첫 비행을 성공적으로 수행하였다. 현재 저주기 피로 시험과 일부 해석을 제외하고 군 인증을 위한 해석 및 시험이 완료 되었으며 2011년 상반기에 인증완료 예정이다.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2010년도 제35회 추계학술대회논문집
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• pp.506-511
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• 2010

본 논문은 한국형 기동헬기(수리온)에 탑재되는 T700/701K 터보 샤프트 엔진의 개발 현황을 기술한다. T700/701K 엔진은 군용 헬기엔진으로 널리 사용되고 있는 GE사의 T700엔진을 후방 구동형으로 최초 개조 개발한 엔진이다. 주요 개발 내용은 크게 엔진 장착 요구조건에 의한 후방 구동형 개조, 동력터빈 성능 향상 및 엔진 운전 신뢰성 향상을 위한 2채널 FADEC 시스템 적용 등이다. 2006년 6월 사업이 착수되어 개발 및 인증시험용 엔진의 초도 운전이 2008년에 성공적으로 수행되었으며 예비비행정격시험 수행을 통해 2010년 3월에 첫 비행을 성공적으로 수행하였다. 현재 LCF 시험과 일부 해석을 제외하고 군 인증을 위한 해석 및 시험이 완료 되었으며 2011년 상반기에 인증완료 예정이다.

• 한국군사과학기술학회지
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• 제14권6호
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• pp.1138-1143
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• 2011

One of the critical items in radar testing is the ability to evaluate the performance of radar systems under real operational environments. But it takes lots of time and cost to operate real targets and analyze the test results due to a large amount of data based on these complicated environments. In this paper, the Radar Simulative T&E Lab. is introduced, and the test and analysis results of the developing radar for predicting the radar system performance are described in the Radar Simulative T&E Lab. This laboratory could be used to test the far-field characteristics of antenna radiation pattern and to perform an effective radar system test and evaluation using a simulative target generator under a low cost repeating test situation.

• 여성건강간호학회지
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• 제7권1호
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• pp.30-43
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• 2001

This was a pre-experimental study to confirm the breast-feeding ability and effect of follow up care on the breast-feeding rate and the breast-feeding method by the mother-infant breast-feeding assessment tool for the mothers who got the breast-feeding education. The subjects were 46 mothers who experienced normal delivery of infants at a college hospital in K-city, Kyungsangbuk-do, from July 1 to October 21, 2000. The instrument for data obtainment were The Mother-Infant Breast-Feeding Assessment Tool of Johnson et al. (1999), and The Breast- Feeding Method Measurement Tool of Jeong, Geum-hee(1997). This instrument was reliable, showing Cronbach $\alpha$.751. This study classified them into 3 groups: at high risk for breast-feeding failure, at risk for breast-feeding problems, and at low risk for breast-feeding failure by the mother-infant breast-feeding assessment tool on the day of discharge from the hospital after delivering individual breast-feeding education to the subjects. This study investigated the breast-feeding rate and the breast-feeding method through mail questionnaire at the four week after childbirth, and through the phone counselling and the home visit for follow up care at the first week and the second week after childbirth. The sixth week after childbirth, this study investigated the breast-feeding rate by phone. The data analyzed the hypothesizes by $x^2$-test, paired t-test, ANOVA, Wilcoxon signed rank test, Wilcoxon rank sum test and trend analysis using SPSS/PC+ WIN 10.0 program. The results were as follows : 1) Hypothesis 1-1, "there won't be any difference the breast-feeding rate of a group at risk for breast-feeding failure by the time elapsed" was supported through constant the breast-feeding rate, because changes in the breast-feeding rate by the time elapsed after childbirth wasn't statistically significant(t= -1.501, p=.270). Hypothesis 1-2, "there won't be any difference the breast-feeding rate of group at low risk for breast-feeding failure by the time elapsed" was supported through constant the breast-feeding rate, because changes in the breast-feeding rate by the time elapsed after childbirth wasn't statistically significant(t=-1.732, p=.225). 2) Hypothesis 2-1, "there won't be any difference between the breast-feeding method of group at risk for breast-feeding failure for four weeks after childbirth and just after childbirth” was rejected, because the mean point of post test appeared to be higher than that of pre test(t=-7.267, p=.000). Hypothesis 2-2, "there won't be any difference between the breast-feeding method of the group at low risk for breast-feeding failure for four weeks after childbirth and just after childbirth" was rejected, because the mean point of post test appeared to be higher than that of pre test(t=-2.501, p=.012). 3)The 3rd hypothesis, "there won't be any difference between breast-feeding method of groups at risk for breast-feeding problems and at low risk for breast-feeding failure at the 4th week after childbirth and just after childbirth" didn't show any difference between the breast-feeding method of groups at risk for breast-feeding problems and at low risk for breast-feeding failure in the advance test(t=-1.521, p=.130) but there was difference between them in post test (t=-2.012, p=.044). As a result, the 3rd hypothesis was supported by pre test, but it was rejected by post test. In conclusion, this study confirmed breast- feeding education and follow up care just after childbirth were effective for the breast-feeding rate and method. Accordingly, it is proposed that successful nursing intervention of breast-feeding to be necessary by continuously providing follow up care through the mother-infant breast-feeding assessment tool as well as to execute individual breast-feeding education to mothers just after childbirth.