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Symptom Prevalence and Related Distress in Cancer Patients Undergoing Chemotherapy

  • Thiagarajan, Muthukkumaran;Chan, Caryn Mei Hsien;Fuang, Ho Gwo;Beng, Tan Seng;Atiliyana, MA;Yahaya, NA
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.1
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    • pp.171-176
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    • 2016
  • Background: Much has been done to examine the psychological impact of cancer treatment, but it remains unclear to what extent anxiety and depression is related to symptom prevalence. The present study concerned the characteristics and frequency of distress as related to symptom prevalence in cancer patients undergoing chemotherapy in Malaysia. Materials and Methods: Participants were 303 consecutive adult cancer patients undergoing chemotherapy in an academic medical center. The short form Memorial Symptom Assessment Scale (MSAS-SF), which covers three domains of symptoms (global distress, physical- and psychological symptoms) was used to cross-sectionally measure symptom frequency and associated distress via self-reporting. One-way ANOVA and t-tests were used to test mean differences among MSAS-SF subscale scores. Results: Complete data were available for 303 patients. The mean number of symptoms was 14.5. The five most prevalent were fatigue, dry mouth, hair loss, drowsiness and lack of appetite. Overall, symptom burden and frequency were higher than in other published MSAS-SF studies. Higher symptom frequency was also found to be significantly related to greater distress in cancer patients undergoing chemotherapy. Conclusions: Patients undergoing chemotherapy suffer from multiple physical and psychological symptoms. Better symptom control or palliative care is needed. Greater frequency of reported symptoms may also indicate a subconscious bid by patients for care and reassurance - thus tailored intervention to manage distress should be offered.

MiR-34b/c rs4938723 Polymorphism Significantly Decreases the Risk of Digestive Tract Cancer: Meta-analysis

  • Ji, Tian-Xing;Zhi, Cheng;Guo, Xue-Guang;Zhou, Qiang;Wang, Guo-Qiang;Chen, Bo;Ma, Fei-Fei
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.6099-6104
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    • 2015
  • Background: Previous studies investigating the association between miR-34b/c rs4938723 polymorphism and cancer risk showed inconclusive. Here, we performed meta-analysis to investigate the association between miR- 34b/c rs4938723 polymorphism and digestive cancer risk. Materials and Methods: Literature database including PubMed, OVID, Chinese National Knowledge Infrastructure (CNKI) were searched for publications concerning the association between the miR-34b/c rs4938723 polymorphism and digestive cancer risk. Results: A total of 6 studies consisting of 3246 cases and 3568 controls were included in this meta-analysis. The combined analysis suggested the miR-34b/c rs4938723 polymorphism significantly reduced digestive cancer risk under allelic model, homogeneous co-dominant model and recessive model (C vs T: OR=0.88, 95%CI=0.82-0.95, p-value=0.001; CC vs TT: OR =0.67, 95%CI=0.57-0.80, p-value=0.000; CC vs TT/TC: OR=0.68, 95%CI=0.58-0.80, p-value=0.000). Q-test and I2 test revealed no significant heterogeneity in all genotype comparisons. The Begger's funnel plot and Egger's test did not show significant publication bias. Conclusions: The current evidence supports the conclusion that the miR-34b/c rs4938723 polymorphism decreases an individual's susceptibility to digestive cancers.

Preparation of Lysine-Coated Magnetic Fe2O3 Nanoparticles and Influence on Viability of A549 Lung Cancer Cells

  • Ma, Yu-Hua;Peng, Hai-Ying;Yang, Rui-Xia;Ni, Fang
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.20
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    • pp.8981-8985
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    • 2014
  • Objective: To explore the effect of lysine-coated oxide magnetic nanoparticles (Lys@MNPs) on viability and apoptosis of A549 lung cancer cells. Methods: Transmission electron microscopy (TEM), vibrating sample magnetometer (VSM) and Zeta potentiometric analyzer were employed to characterize Lys@MNPs. Then Lys@MNPs and lung cancer A549 cells were co-cultured to study the effect of Lys@MNPs on cell viability and apoptosis. The pathway of Lys@MNPs entering A549 cells was detected by TEM and cell imaging by 1.5 T MRI. Results: Lys@MNPs were 10.2 nm in grain diameter, characterized by small size, positive charge, and superparamagnetism. Under low-dose concentration of Lys@MNPs (< $40{\mu}g/mL$), the survival rate of A549 cells was decreased but remained higher than 95% while under high-dose concentration ($100{\mu}g/mL$), the survival ratewas still higher than 80%, which suggested Lys@MNPs had limited influence on the viability of A549 cells, with good biocompatibility and and no induction of apoptosis. Moreover, high affinity for cytomembranes, was demonstrated presenting good imaging effects. Conclusion: Lys@MNPs can be regarded as a good MRI negative contrast agents, with promising prospects in biomedicine.

FEEDING RICE STRAW SUPPLEMENTED WITH UREA-MOLASSES LICK BLOCK TO LACTATING COWS IN BHUTAN

  • Ghebrehiwet, T.;Wangdi, P.;Ibrahim, M.N.M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.7 no.3
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    • pp.421-426
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    • 1994
  • Twelve cross bred cows ($300{\pm}20kg$) were fed a basal ration consisting of 1 kg concentrate and untreated or urea treated rice with or without urea-molasses-wheat bran lick block supplementation. The lick blocks were prepared locally using cement as a binding agent. The experiment lasted for 48 days consisting of a preliminary period of 14 days and a measurement period of 34 days. Daily dry ma tter intake (DMI) of straw and lick block, and daily milk yield were recorded during the measurement period. Intake of lick block when fed with untreated straw (US) was significantly higher (p < 0.01) than with urea treated (TS) straw (397 vs 307g $100kg^{-1}$), but lick block supplementation did not significantly affect the in take of US (1.80 vs 1.83kg $100kg^{-1}day^{-1}$) or TS (2.27 vs 2.17kg $100kg^{-1}day^{-1}$). Both urea treatment and lick block supplementation significantly increased (p < 0.01) the milk yield of cows, and the increase due to urea treatment was higher than that due to lick block supplementation. Benefit/cost ratio obtained for feeding US or TS with 1 kg dairy concentrate was similar (5.4), but the marginal return favours TS (5.4:1.0). The benefit/cost ratio for US and TS supplemented with lick block was 3.4 and 3.7. respectively, but the marginal return with US was higher than with TS (1.6:1.0 and 0.9:1.0, respectively).

The Bans on Po in the Early Years of the Joseon Dynasty (조선 초기 포화 금지령)

  • Choi, Kyu-soon;Koh, Bouja
    • The Research Journal of the Costume Culture
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    • v.13 no.5 s.58
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    • pp.729-742
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    • 2005
  • This paper studied the ban on 'Po[포]', including hemp and ramie, on the basis of Joseon Wangcho Silok (the True Record of Joseon Dynasty). Po is the important point which can help to understand the people's life related with clothing. This paper showed that in the early years of the Joseon Dynasty, the state had forced kinds of bans on some fabrics many times. Among the bans of the fabrics-making the main part was the bans on Po, along with rice, used as money in those days. The state had on Po enacted on the policy to intend to promote paper money circulation more widely. However, people didn't want to use paper money. The reason why cloth could be practical and functional as a kind of currency was that people could make clothes with it at any time while they used it as money. People avoided using paper money that could not be used in that way, and so did public officials. At that time, Po that was generally used as money was the hemp of five warp threads. The measurement of the hemp in 7chi[촌; a Korean inch] by 35chok[척] and 32cm by 16m by modern metric. It also showed that it has been thought that the blended fabrics are the fabrics that were made of raw silk-threads and cotton threads as warp and weft respectively. However, the fact that there is a record of 'Jeo Ma Gyo Jik Po[저마교직포의]'(blended fabrics and clothes made of ramie and hemp) and there appear the new proofs of the fieldwork investigation shows that the concept of blended fabrics might be various or changeable as time passed.

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A Study of Occurrence and Alternating Current of a Matal Kwan in Korean Ancient Times (한국 고대 금속관의 발생과 그 교류에 관한 연구)

  • 진미희;권영숙
    • Journal of the Korean Society of Clothing and Textiles
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    • v.19 no.2
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    • pp.297-316
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    • 1995
  • The system and symbolizing ideologic meanings of the metallic Kwon in period of the Three-Kingdoms were comsidered by comparing to their cultural path and structal styles throughout the tree and the deer worship ideology. The results of this study are as followings; Firstly, the beginning of the Korean, mostly northern style was originated from metal tools of the Bronze age in BC 6c-7c. The maJ;lufature of the metallic adornment brought the pr-evailing use of metallic objects of craftwork after the supply of ironmongery. Secondly, the cultmal characteristics of the metallic Kwan in the kor-ean Peninsula were influenced f-rom the northern chinese tribes, Momg Go, Hung No, and Sien-pi who were transmitted from the scythian of the southern Russia having a prefenence for gold. Thir-dly, the metallic Kwon of the Kogmgo and the Baekje era was ideologically based on the ar-t of Buddism of the pattern of blazing flame, the carved pattern of flower- of herb, and the honey. sukle which were tramsmitted to china thr-ough the silk noad. Fourthly, the metallic K wam of the silla era consisted of the tree and the antler types in closely nelated to the tree and the deer ideology which were based on the background of shamanism. It should be raid that the metallic Kwan of the silla esa are connected to the type of nor-them ancient K wan. Lasthy, the metallic Kwan-Mo of the Kaja esa was mosthy original type of flower of herb even if kome of these ar-e similiar to the tree adornment type of silla. This type of flower of herb in based on the scythian type with a statue im silveer founded at Alexandnopol in the southern russia.

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Development and Evaluation of Core Collection Using Qualitative and Quantitative Trait Descriptor in Sesame (Sesamum indicum L.) Germplasm

  • Park, Jong-Hyun;Suresh, Sundan;Raveendar, Sebastin;Baek, Hyung-Jin;Kim, Chung-Kon;Lee, Sokyoung;Cho, Gyu-Taek;Ma, Kyung-Ho;Lee, Chul-Won;Chung, Jong-Wook
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.60 no.1
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    • pp.75-84
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    • 2015
  • Sesame (Sesamum indicum L.) is one of the most important oilseed crops with high oil contents and rich nutrient value. The development of a core collection could facilitate easier access to sesame genetic resources for their use in crop improvement programs and simplify the genebank management. The present study was initiated to the development and evaluation of a core collection of sesame based on 5 qualitative and 10 quantitative trait descriptors on 2,751 sesame accessions. The accessions were different countries of origin. About 10.1 percent of accessions were selected by using the power core program to constitute a core collection consisting of 278 accessions. Mean comparisons using t-test, Nei's diversity index of 10 morphological descriptors and correlation coefficients among traits indicated that the existing genetic variation for these traits in the entire collection has been preserved in the core collection. The results from this study will provide effective information for future germplasm conservation and improvement programs in sesame.

A Study on the Current Status of Baekje Parade Costume Shown in Festivals - Focusing on Hanseong Baekje Cultural Festival and Yeongam Wangin Cultural Festival - (축제에서 재현된 백제행렬복식의 현황연구 - 한성백제문화제와 영암왕인문화축제를 중심으로 -)

  • Ma, Yoo-Ree;Kim, Eun-Jung
    • Journal of the Korea Fashion and Costume Design Association
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    • v.17 no.2
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    • pp.27-43
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    • 2015
  • Festival costume shown in festival parades targeting historical events or figures helps to understand the theme of festival and grants visual effects and at the same time, is an important factor to identify then-cultural environment. Accordingly, this study aims to make a periodic review of traditional costumes used in parades for Hanseong Baekje Cultural Festival and Yeongam Wangin Cultural Festival which are both the festivals that backgrounded Baekje period, make a comparative analysis of the archetypes of reproduction costume vs Baekje costume, understand the problems of festival costume, and seek developmental directions. After making a comparative analysis of reproduction costume shown in festival parades, it was found that king costume, queen costume, governmental official costume, and humble class costume were all different from Baekje costume in terms of configuration, materials, color, shape, and creating method of costumes, and problems were drawn. When it comes to costume items, Pasul and Danryungpoh that didn't belong to Baekje period were worn. The problems in color research can be identified in governmental official costume. The problems in type of costume are shown in the length of po worn outside, margin of width, and degree of restoring accessories. Therefore, it seems to be necessary to convey and identify costume creating method by festival parade-related persons.

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The Effects of Mental Health and Family Problem Solving Communication on Cancer Adjustment of Women with Cancer in Nursing Hospital (요양병원 여성 암 환자의 정신건강, 가족문제해결 의사소통이 암 적응에 미치는 영향)

  • Lim, Sunyoung;Ma, Ryewon;Park, Hyesun
    • Journal of The Korean Society of Integrative Medicine
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    • v.8 no.2
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    • pp.29-39
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    • 2020
  • Purpose : This study investigated the relationship among adjustment of cancer, mental health, and family problem solving communication of women with cancer. The purpose of this study was to determine how to improve the adjustment of cancer of women and improve women's mental health to form family problem solving communication. Methods : This correlational study was conducted among 101 women with cancer living in the Seoul region. Data collection occurred from August 1, 2018, to August 23. The data are reported as means and standard deviations and were analyzed with t tests, ANOVA, and Pearson's correlation regression using SPSS version 21.0. Results : The results of this study showed that adjustment to cancer significantly correlated with the education level of the participants (F=3.27, p<.05) and self-help group participation (F=3.156, p<.05). In this study, the mental health of female cancer patients significantly affected their adjustment to cancer (F=13.13, p<.001). These results explained 19.7% of the variance (F=13.13, p<.001) in mental health and adjustment to cancer in female cancer patients. Conclusion : In this study, mental health was significantly affected adjustment to cancer. The results suggest that adjustment to cancer can be promoted through the development and application of a nursing intervention program considering the mental health of female cancer patients. In addition, further research is required to identify the factors in consideration of various variables in addition to the sociodemographic and disease-related variables that may affect the adjustment to cancer of female cancer patients in nursing hospitals.

Preferences of Koreans and Foreigners for Traditional Recipe Developed containing Deoduk (더덕을 이용한 음식의 전통레시피 개발과 내·외국인의 선호도)

  • Chang, Seo Young;Kim, Na Young;Ma, Yujie;Han, Myung Joo
    • Journal of the Korean Society of Food Culture
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    • v.29 no.1
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    • pp.44-53
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    • 2014
  • Various Korean healthy foods containing Deoduk were developed and standardized recipe. Sensory evaluations of Koreans and foreigners for these developed foods were performed by using the 5-point hedonic scale. The results of the sensory test on foods containing Deoduk were as follows: Deoduk bap (2.90~3.91), Deoduk seolgidduk (3.19~4.40), Deoduk gangjeong (3.00~4.60), riasted Deoduk with red pepper paste (2.73~4.20), Deoduk pine nut juice salad (2.40~3.96), and Seopsansam (3.91~3.81). Deoduk seolgidduk, developed by using a recipe for Sansambyeong which in a Chosun dynasty cook-book, was highly preferred by Africans, Japanese, and Koreans. In particular, all foreigners except Southeast Asians liked Deoduk gangjeong, and both Koreans and foreigners liked Seopsansam. Foreigners' experience of eating foods containing Deoduk was high at 'No' (68.9%), whereas Japanese (60.0%) had previous experience. Exactly 91.6% of Koreans responded 'Yes' to the question of whether or not Deoduk food is good for health, whereas the proportion of foreign respondents who said 'Yes' was 43.2%, 'No' was 5.4%, and 'I don't know' was 51.4%. Deoduk seolgidduk was preferred by Japanese, and most foreigners preferred Deoduk gangjeong and Seopsansam. Therefore, Deoduk could be developed as a healthy food for globalization of Korean food. However, as foreigners' awareness of Deoduk is low, we must positively promote the health function of traditional food ingredients and develop various menus suitable forforeigners' tastes for the globalization of Korean food.