• 제목/요약/키워드: t,t-MA

검색결과 632건 처리시간 0.025초

액체$N_2$중 절연재료의 부분방전 열화 연구 (Study of Partial Discharge Degradation of Insulating Materials in Liquid Nitrogen)

  • 김현희;김상현;마대영;장종근;남궁도;조전욱
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1995년도 추계학술대회 논문집 학회본부
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    • pp.406-410
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    • 1995
  • A superconducting cable is one of the promising methods of undground transmission of high electric power in the future. It is very important that composite insulation system of $LN_2$ and polymer films takes into consideration for application high $T_c$ superconductor. This study is about both the partial discharge and properties V-t in $LN_2$. As result, applied voltage doesn't depend on the radius of non-eroded area but eroded area. And eroded area is observed the formation such as the ring of a tree.

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A new bridge-vehicle system part I: Formulation and validation

  • Chan, Tommy H.T.;Yu, Ling;Yung, T.H.;Chan, Jeffrey H.F.
    • Structural Engineering and Mechanics
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    • 제15권1호
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    • pp.1-19
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    • 2003
  • This paper presents the formulation of a new bridge-vehicle system with validation using the field data. Both pitching and twisting modes of the vehicle are considered in the contribution of the dynamic effects in the bridge responses. A heavy vehicle was hired as a control vehicle with known axle weight, axle spacing and spring coefficients. The measured responses were generated from the control vehicle running at a particular speed at a test span at Ma Tau Wai Flyover. The measured responses were acquired using strain gauges installed beneath the girder beams of the test bridge. The simulated responses were generated using BRVEAN that is a self-developed program based on the proposed bridge-vehicle system. The validation shows that the bridge model is valid for representing the test bridge and the governing equations are valid for representing the motion of moving vehicles.

글루타메이트에 의해 산화적 스트레스를 받은 HT22 세포주에서 포공영의 신경세포 보호 활성 (Neuroprotective Effect of Taraxacum platycarpum Extract Against Glutamate-induced Oxidative Stress in HT22 Cells)

  • 이현우;마충제
    • 생약학회지
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    • 제50권2호
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    • pp.118-123
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    • 2019
  • Glutamate acts as an important neurotransmitter in brain. However, high concentration of glutamate showed an excitatory neurotoxicity and resulted to neuronal cell death. Neuronal cell death is known for one of the reason of Alzheimer's disease, a neurodegenerative disease. We tried to find neuroprotective medicinal plants by neuroprotection activity against glutamate injured HT22 cells as a model system. In the course of bioscreening of various medicinal plants, Taraxacum platycarpum extract showed significant neuroprotective activity. We tried to elucidate mechanisms of neuroprotective activity. T. platycarpum extract reduced ROS and intracellular $Ca^{2+}$ concentration increased by glutamate induced neurotoxicity. In addition, mitochondrial membrane potential was restored to the control level. Also, glutathione level, glutathione reductase and glutathione peroxidase activity were increased by T. platycarpum extract treatment. These data suggested that T. platycarpum showed neuroprotective activity via antioxidative activity.

STUDIES ON IMMUNOTOXIC POTENTIAL OF METHAMPHETAMINE (MA) IN Balb/C MICE I. Changes of Lymphoid Organs and Inhibitory Effect of Lymphocyte Proliferation to Mitogen

  • Lim, Chae-Woong;Rim, Byung-Moo;Lee, Ho-Il;Kim, Sang-Ho
    • Toxicological Research
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    • 제11권1호
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    • pp.9-14
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    • 1995
  • The immune system is partially under the control of the sympathetic and parasymphathetic nervous systems through the regulatory feedback loop. Methamphetamine (MA) is a neurotoxic chemical which affects the neurotransmitter system. The objective of this study was to investigate the immunotoxic effect of MA on the major immune target organ and lymphocyte proliferation to the various mitogens. Female Balb/C mice, 15 to 20 g, were injected subcutaneously with 0, 0.5, or 5 mg MA/kg for 14 consecutive days. In MA treated mice, the body weight gain and relative spleen and thymus weight were decreased in doserelated manner. Histopathologically, there was a paucity of lymphold follicles and germinal centers in the spleen, and thymic cortical atrophy with lymphophagocytosis was prominent. Apoptosis also occurred in germinal centers of spleen and thymic cortex. The threshold and peak of lymphocyte proliferation at various concentration of mitogens showed similar patterns. However, the response to lipopolysaccaride (LPS) and pokeweed mitogen (PWM) in the 5 mg MA/kg treated group showed threshold and peak proliferation at high concentration of mitogens (25${\mu}g$ LPS/ml for MA vs 15${\mu}g$ LPS/ml for control; 60${\mu}g$ PWM/ml for MA vs 45${\mu}g$ PWM/ml for control), which suggest that MA impairs T cell dependent-B cell function. This preliminary study indicated that MA affected the lymphold organs and immune function.

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STUDIES ON IMMUNOTOXIC POTENTIAL OF METHAMPHETAMINE (MA) IN Balb/C MICE II. The Functional Alteration of Effector Cells in Immune System

  • Lim, Chae-Woong;Rim, Byung-Moo;Lee, Ho-Il;Kim, Sang-Ho
    • Toxicological Research
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    • 제11권1호
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    • pp.15-21
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    • 1995
  • Several populations of lymphocytes possess receptors for autonomic neurotransmitter, which make lymphocytes susceptible to autonomic stimulation. This study was to evaluate the functional alternation of effector cells of the immune system. Female Balb/C mice, 15-20 g, were injected with MA subcutaneously under various conditions. Mixed lymphocyte reaction (MLR) showed certain T cell subsets were affected by MA. The level of interleukin-2 (IL-2) production was inhibited due to a defect in expression of the IL-2 receptor. In mice injected with 20 mg MA/kg, 1 day before assay, phagocytosis of peritoneal macrophages showed $14.07\pm3%$, which was similar degree to 5 mg MA/kg treatment for 4 consecutive days. Phagocytosis was almost recovered to that of control after 4 day in 20 mg/kg injected mice. Maximum inhibition of plaque forming cell (PFC) occurred when MA was given early, indicating the inductive time point of antibody production was affected. The cortisol level increased in the MA treated group (0.05, 0.20, and $0.08{\mu}g$/dl for control, low, and high dose-MA treated mice, respectively). Based on these results, MA has general suppression effects on the immune systems by functional alteration of effector cells. Considering the increment of serum cortisol levels, MA partially impacts the neuroendocrine system to lead to failure of immune response.

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저장 및 저장후 유통조건에 따른 마늘(Allium sativum L.)의 생리적 특성 변화 (Changes in Physiologcal Properties of Garlic (Allium sativum L.) by Storage and Marketing Condition after Storage)

  • 최선태;장규섭
    • 한국식품저장유통학회지
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    • 제5권2호
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    • pp.105-110
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    • 1998
  • To find out suitable storage and marketing condition, northern type 'seosan' garlic was stored for 3 months at controlled atmosphere(CA), modified atmosphere(MA), low(0~1$^{\circ}C$) and room temperature(20$\pm$5$^{\circ}C$), and then marketed at low(2~3$^{\circ}C$) and room temperature (20$\pm$5$^{\circ}C$)after storage. The physiological properties of garlic were investigated among treatments. The garlic respiration increased after 2 months at room temperature storage, which seem to be dormancy break time. During storage of garlic by CA, MA condition, sprouting and weight loss were prevented effectively by suppress of respiration, and hardness was maintained higher then those of the others. Decay rate occurred 8.1% at room temperature storage, 2% at MA storage but didn't occurred at CA and low temperature storages. When marketed at room and low temperature after storage, increment of respiration and sprouting were delayed, and changes of weight and hardness were low in garlics stored at CA and MA. Decay rate occurred high in garlics stored at MA and room temperature.

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사례 조사를 통한 백화현상의 특징 및 저감 방안 연구 (The study on characteristic of efflorescence phenomenon and reduction plan through research)

  • 박영민;이희두;이해진;임남기
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2002년도 학술논문발표회
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    • pp.1-6
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    • 2002
  • The study offer a suggestion that from result in being a case to efflorescence for decrease a plan: $\circled1$ A efflorescence of concreat a structure will be the prograss plan; In the materials, depress use to the water-sand in the construction, admonish unification of front and rear in the environment, consideration requisite concreat don't the occurrence efflorescence. $\circled2$ Ma sonry building efflorescence establish a ventilation opening and a waterway to ma sonry the times avoid the winter or the rainy season. Ma sonry building efflorescence will be make good among a brick to a brick interval closely mortar. $\circled3$ Tile building, tile of plasticity temperature is appropriate, reduce the deviation, parapet part of efflorescence will be make good closely mortar. A construction material part a meterial developing need Perfection of construction a efflorescence occurrence is the minimum, a plan Part developed so on, composition of a ommection field systematic effort need a efflorescence Prevention a kind of detail.

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Identification of Chinese Yam Necrotic Mosaic Virus(ChYNMV) infecting Chinese yam(Dioscorea opposita Thunb. cv. Jang-Ma) in Korea.

  • D. K. Kang;H. Y. Shin;J. H. Sung;Park, J. H.;M. U. Chang
    • 한국식물병리학회:학술대회논문집
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    • 한국식물병리학회 2003년도 정기총회 및 추계학술발표회
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    • pp.151.1-151
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    • 2003
  • Chinese yam(D. opposita Thunb. cv. Jang-Ma) plants showing necrotic mosaic symptom were collected from their growing fields in Andong, Korea. Electron microscoptic examination of negatively stained preparations showed filamentous particles of 660nm in length. The virues purified partially were used to isolate Viral RNA as template for RT-PCR to amplify the CP gene with ChYNMV specific and oligo dT primers. Amino acids sequeces revealed that the viruses shared 99.3% similarity with ChYNMV(AB044386) which was known as the member of macluravirus. So the viruses from Chinese yam(D. opposita Thunb. cv. Jang-Ma) plants were identified as ChYNMV. Comparing the amino aced sequences of ChYNMV strains with other macluraviruses such as CdMV, NLV and MacMV revealed that N-terminal was the most variable region and conserved regions were present within the genus Macluravirus.

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