• Journal of Periodontal and Implant Science
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• v.42 no.1
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• pp.3-12
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• 2012

Purpose: Anti-rheumatic agents target common molecular pathways of inflammation in rheumatoid arthritis (RA) and periodontitis. The purpose of this study was to determine the relative effect of anti-rheumatic agents on the levels of inflammatory biomarkers and periodontal inflammation in RA patients with periodontitis. Methods: A systematic review and meta-analysis were conducted of studies comparing periodontal parameters of inflammation, such as bleeding on probing, and biomarkers of inflammation in RA patients with periodontitis and healthy adults with and without periodontitis. The search included the electronic databases MEDLINE, Cochrane Database of Systematic Reviews, and Google Scholar, inclusive through October 2011, with no language restrictions. Hand searches were conducted of the bibliographies of related journals and systematic reviews. Observational and interventional studies assessing the effects of antirheumatic therapy qualified for inclusion. Two reviewers performed independent data extraction and risk-of-bias assessment. Of the 187 identified publications, 13 studies fulfilled the inclusion criteria. Results: When compared to healthy adults without periodontitis, RA subjects were found to have significantly higher levels of bleeding on probing and limited evidence of higher levels of interleukin-$1{\beta}$ and tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) in gingival crevicular fluid and saliva. No consistent differences were found in periodontal parameters and inflammatory biomarkers between RA subjects and adults with periodontitis. Studies evaluating the effect of anti-TNF-${\alpha}$ therapy in RA subjects with periodontitis have yielded inconsistent results. Conclusions: There are limited data, however, to suggest that anti-TNF-${\alpha}$ agents can reduce local production of inflammatory cytokines and periodontal inflammation in RA patients with periodontitis.

• Journal of Korean Medicine Rehabilitation
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• v.33 no.2
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• pp.19-32
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• 2023

Objectives The purpose of this study is to systematically review the degree of pain and function improvement in acupuncture treatment for patellofemoral pain syndrome (PFPS). Methods Randomized controlled trials (RCTs) were searched from Medline/PubMed, Cochrane Library, Embase, WanFang Data, China National Knowledge Infrastructure (CNKI), Citation Information by NII (CiNII), Koreanstudies Information Service System (KISS), ScienceON, KoreaMed, and Korean Medical Database (KMbase). The methodological quality of selected RCTs' were evaluated according to Cochrane RoB2 tool. Results Total of 158 studies were identified and 7 RCTs were selected for systematic review. Frequently used evaluation method were visual analogue scale and Kujala scores. All studies showed significant effect on pain reduction and knee function between before and after treatment, but showed partial significance between the intervention and control group. Conclusions Research showed that acupuncture treatment is an effective treatment for improving the pain and function of PFPS, but it is difficult to conclude that it has a significant effect compared to other treatments. Selected studies included subjective evaluation indicators and the total of selected studies were small, so the interpretation of the results is limited. Also most of the included studies are evaluated to have some concerns of bias. Therefore, subsequent research should continously be done in more objective and systematic method.

• The Journal of Korean Society for School & Community Health Education
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• v.18 no.2
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• pp.27-42
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• 2017

Objectives: The purpose of this study was to investigate the characteristics of smoking prevention programs and their effectiveness for Korean school-aged children and adolescents by using systematic review and meta-analysis. Methods: Electronic searches were performed in RISS, NAL, DBPia, KISS using keywords according to inclusion criteria. 21 studies published from 2003 to the first half of 2017 that dealt with effects of smoking prevention programs for school-aged children and adolescents were selected for systematic review. Results: All 21 studies were quasi-experimental research designs. More than half of the programs(66.7%) were conducted for male and female. Most of the programs were conducted more than once a week(71.4%). 14 studies(66.7%) did not report using a theoretical model. Five dependent variables(knowledge of smoking, attitude toward smoking, non-smoking intention, self-assertiveness, and self-efficacy) were selected to measure the effectiveness of the smoking prevention programs. Knowledge of smoking was the most effective at hedge's g=0.673. Self-efficacy and self-assertiveness variables were statistically significant at hedge's g=0.461 and hedge's g=0.279, respectively. Effect sizes of attitude toward smoking and non-smoking intention were not statistically significant compared to the control group. As a result of the moderator effect analysis on the knowledge of smoking variable, the statistically significant variables were 'gender of participants'(p<0.01) and 'duration of the program'(p<0.001). Conclusions: The results of this study using systematic review and meta-analysis will be evidence-based data for researchers conducting smoking prevention programs in school-aged children and adolescents.

• Journal of Korean Medicine Rehabilitation
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• v.32 no.3
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• pp.29-35
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• 2022

Objectives The purpose of this systematic review is to analyse randomized controlled trials about acupuncture for patellofemoral pain syndrome (PFPS) and evaluate it's pain improvement effect. Methods Studies will be searched from ten databases (Medline/PubMed, Cochrane Library, EMBASE, China National Knowledge Infrastructure [CNKI], WanFang Data, Citation Information by NII [CiNII], ScienceON, Koreanstudies Information Service System [KISS], KMBASE, and KoreaMed). Participants will be patients diagnosed with PFPS, regardless of cause, gender, age or race, and interventions will be acupuncture, electroacupuncture, dry needling, fire needle, and acupotomy. Other treatments than interventions will be the control group and the main outcome will be reviewed by visual analogue scale (VAS). Results Data will be extracted and assessed according to the Preferred Reporting Items for Systematic Review and Meta-Analysis flow chart and Cochrane risk of bias tools. Meta-analysis will be conducted using random effect model within 95% confidence interval. Conclusions We expect this systematic review to provide useful data about the pain improvements of patellofemoral pain using acupuncture and expect to stimulate and systematize acupuncture treatment on PFPS in the future.

• Journal of Acupuncture Research
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• v.27 no.6
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• pp.1-10
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• 2010

Objectives : The aim of this systematic review was to assess the efficacy of acupuncture and its relevant modality on post-stroke muscle spasticity Methods : We included 7 randomized controlled trials(RCTs) and 1 crossover study on acupuncture on the post-stroke muscle spasticity. Articles searches were performed in various databases in October 2009. Eight studies from 38 articles met the inclusion criteria and were used to assess the quality of clinical trials by means of Jadad scale, STRICTA, CONSORT statement and cochrane-handbook for systematic reviews of interventions. Results : Electrical stimulation such as electroacupuncture and TENS on acupoints was used in five studies. Repeatition of electroacupuncture showed significant decrease of the post-stroke muscle spasticity and persistence of the effect. Only three studies were assessed high quality as the methodological assessment tool(Jadad scale) and none of the studies matched STRICTA recommendations. Conclusions : This systematic review shows that there is beneficial effects of electroacupuncture on the post-stroke muscle spasticity. Further study of large population with high methodological quality will be needed.

• Korean Journal of Construction Engineering and Management
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• v.7 no.1 s.29
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• pp.55-63
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• 2006

As value engineering in design phase is big in the effect of application, analysis by systematic procedures is required. The most important part is the stage of creation for making of idea. It takes much time for us to make good idea involving the brainstorming and delphi in recent making idea. It is expected because most experts in participating in design value engineering is to approach with less effective method. In this study we suggest that application of ASIT(Advanced Systematic Inventive Thinking) is the method as way of creative idea making. ASIT is expected to perform Idea making with systematic procedure and to create effective idea in short time.

• Journal of Korean Biological Nursing Science
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• v.22 no.3
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• pp.157-171
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• 2020

Purpose: The purpose of this study was to analyze the characteristics and effects of the forest therapy programs for adult patients. Methods: Six databases (PubMed, Cochrane library, CiNii, PsychoInFO, AGRICOL, EMBASE) and six domestic databases were systematically searched with language restrictions of Korean, English, and Japanese. The systematic review was based on the Preferred Reporting Items Systematic Reviews and Meta-Analysis (PRISMA) flow diagram. Results: Twenty five studies met the inclusion criteria. A systematic review identified adult patients classified as 1) disease of the circulatory system, 2) mental and behavioral disorders, 3) malignant neoplasms, 4) etc. (diabetes mellitus, chronic pain). This integrative review showed a positive effect of the forest therapy program for adult patients on physiological indices such as blood pressure, heart rate, heart rate variability, level of stress hormone, and natural killer cells as well as social·psychological indices such as the Profile of Mood States (POMS), anxiety, depression, and quality of life. Conclusion: The results of this study could be useful key principles in developing and applying the forest therapy programs in nursing intervention. Further research should be conducted to develop the forest therapy programs suitable for each patient group and measure its effectiveness.

• Korean Parent-Child Health Journal
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• v.22 no.1
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• pp.30-42
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• 2019

Purpose: This study was a systematic review and meta-analysis designed to evaluate the effects of breastfeeding individual visit program. Methods: Based on the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA), a systematic search was conducted using four core electronic databases from October 28, 2018 to November 14, 2018. The topics of breastfeeding individual visit program were analyzed using descriptive analysis and the effects of intervention were meta-analyzed using the Review Manager 5.3 software. Results: A total of 13 studies were included in the review and 12 were included for meta-analysis. Breastfeeding individual visit programs were found to be more effective in breastfeeding rates, attitude, skill and self-efficacy compared to group education or non-education. Conclusion: Effective breastfeeding education can help mothers to start and sustain breastfeeding. Breastfeeding individual visits programs that are more effective than group education to maintain breastfeeding for pregnant women should be developed and applied.

• Restorative Dentistry and Endodontics
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• v.46 no.2
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• pp.19.1-19.12
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• 2021

Objectives: The purpose of this study was to conduct a systematic review and meta-analysis of in vitro studies regarding the effectiveness of reciprocating and rotary instrumentation on microbial reduction in root canals. Materials and Methods: PubMed, Scopus, Web of Science, the Cochrane Library, and the gray literature were searched through December 2019. Studies comparing the influence of reciprocating and rotary instrumentation on the removal of microorganisms from root canals that quantified the antimicrobial effect were included. Data extraction was completed using a systematic form for data collection. The risk of bias of the studies was evaluated. Standardized mean differences (SMDs) and confidence intervals (CIs) were calculated using a random effects meta-analysis. Results: Seventeen in vitro studies were included in this systematic review, of which 7 provided adequate data for inclusion in the meta-analysis. Both reciprocating and rotary systems were similarly effective in reducing the microbial load in infected root canals (SMD [95% CI], 0.0481 [-0.271, 0.367]). Three studies showed a low risk of bias, whereas most of the studies (82%) presented a medium risk. Conclusions: Although both techniques decrease the microbial content (with reductions of 23.32%-88.47% and 23.33%-89.86% for reciprocating and rotary instrumentation, respectively), they are not able to provide complete disinfection of root canals.

• Bulletin of the Korean Chemical Society
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• v.16 no.9
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• pp.845-850
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• 1995

A systematic method is presented to analyze the bandgaps of conjugated polymers in terms of geometrical relaxations and electronic effect of moieties using the equation of Eg=ΔEδr + ΔE1-4 + ΔEel. The relationship between ΔEδr and δr is derived from trans-PA and is transferred to other conjugated polymeric systems. By applying this method to heterocyclic polymers, very useful information is obtained to understand the evolution of bandgaps of PT, PPy and PF in connection with the chemical structures and electronic effect of the heteroatoms. We believe that this method is very helpful to understand the evolution of bandgaps of various conjugated polymers in connection with the chemical structures and electronic effect of moieties. Also, the method is expected to provide valuable information to design a small bandgap polymers.