• 한국융합학회논문지
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• 제8권4호
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• pp.131-137
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• 2017

본 연구에서는 Computer-Aided Design (CAD) 모델로부터 4D CT 데이터로 변환하는 프로그램을 개발하였다. 개발된 프로그램의 성능을 확인하기 위해, 공학과 의학의 융합 모델로 인체 호흡을 모사할 수 있는 호흡모사 팬텀을 CAD 기반 프로그램으로 모델링하였으며, 이 모델을 10개의 위상영상을 포함하는 DICOM형태의 4D CT 데이터로 변환하는 CAD2DICOM을 개발하였다. 이후, 제작된 4D CT 데이터의 정확성 및 유효성을 평가하기 위하여 영상의 해상도, 종양의 체적 및 위치 등을 방사선치료계획시스템을 이용하여 평가하였다. 결과적으로, 제작된 4D CT 데이터가 방사선치료계획시스템 상에 정상적으로 인식됨을 확인하였으며, 모든 위상에서 종양 체적은 8.8cc로 차이가 나타나지 않고 종양의 움직임도 설정된 10mm로 나타나 정확히 반영됨을 확인하였다. 본 연구를 통해 개발된 프로그램을 이용하면 실제 4차원 CT 촬영에서 발생할 수 있는 영상의 인공물(허상)이 없는 표준 영상을 획득할 수 있으므로, 향후 움직임에 민감한 4차원 방사선 치료계획연구 및 4차원 방사선 영상 평가연구 등에 활용될 것으로 사료된다.

• 한국멀티미디어학회논문지
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• 제5권4호
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• pp.372-385
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• 2002

본 논문에서는 실시간 멀티미디어 데이터를 위한 효율적인 버퍼 교체 기법을 제안한다. 제안하는 기법은 실시간 특성을 고려하기 위해 다단계의 우선순위 레벨을 갖는다. 각 우선순위 레벨은 처음 참조된 데이터를 위한 콜드 셋(cold set)과 재 참조된 데이터를 위한 핫 셋(hot set)으로 구분된다. 희생 데이터 선정 작업은 버퍼 할당을 요구하는 트랜잭션의 우선순위 레벨보다 낮은 레벨만을 대상으로 콜드 셋의 최하위 레벨부터 핫 셋의 최상위 레벨까지 순차적으로 수행된다. 콜드 셋의 각 레벨에서는 가장 큰 미디어부터 교체 대상으로 선정하고, 핫 셋의 각 레벨에서는 가장 긴 참조 간격을 갖는 미디어부터 선정한다. 이로 인해 한정된 버퍼 공간에 많은 수의 인기 있는 미디어를 오랫동안 유지시킬 수 있으므로 버퍼 히트 비율이 증가되고, 많은 수의 서비스 요청을 처리할 수 있게 되어 전체적인 시스템 성능은 향상된다. 제안하는 기법에 대한 성능 평가에서는 Priority-Hints 기법을 대상으로 버퍼 히트 비율 및 트랜잭션의 마감시간 초과 비율을 비교한다. 이를 통해 기존의 기법들보다 제안하는 기법의 성능이 뛰어남을 보인다.

• 한국산학기술학회논문지
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• 제18권11호
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• pp.770-777
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• 2017

BIM(Building Information Modeling)은 2000년대 들어서면서 기존의 CAD를 대신하여 통합정보모델로서의 관심과 기대를 받아왔다. 건설산업 전체 중에서 건축분야에서 먼저 활용되기 시작한 BIM기술은 토목분야에서는 상대적으로 늦게 도입이 되기 시작하였다. 그러나 정부에서 2020년부터 모든 SOC사업의 20%를 적용계획을 발표하는 등 토목사업에서의 도입은 가속화 될 것으로 예상된다. BIM을 성공적으로 도입하기 위해서는 통합적 설계정보에 대한 체계적인 구조와 이를 구현하는 기술이 뒷받침되어야 한다. 또한 건설사업에서 정보화는 많은 복잡한 요소들이 얽혀 있어 정보체계간의 관계 정립이 무엇보다 중요하다. 본 연구에서는 토목사업에 BIM을 도입하기 위한 정보관계를 규명하여 통합정보를 구성하기 위한 프레임워크를 제시하고 이를 교량사업에 적용하여 그 효용성을 확인한다. 본 연구는앞으로 토목분야에서 WBS(Work Breakdown Structure)를 BIM에 도입하여 공정 및 공사비 관리를 통합적으로 수행하는데 활용될 수 있다. 또한 BIM을 도입하기 위한 정보체계의 표준화에 대한 방향제시를 통하여 앞으로 토목의 각 분야에서 BIM을 도입하는데 도움이 될 것이다.

• 정보처리학회논문지D
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• 제10D권6호
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• pp.885-896
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• 2003

무선인터넷 기술의 발달과 응용의 확산으로 인하여 위치정보(Location Information)를 이용한 서비스 형태는 아주 다양하여 지고 있으며, LBS(Location-Based Services)라는 형태로 국내외 시장에서 급속히 학장하고 있다. 이러한 서비스의 기본정보인 위치정보는 고부가가치의 정보로 인정되고 있으며 또한 이러한 위치를 기반으로 한 서비스는 기존의 GIS(Geographic Information System)를 일반사람들에게 생활 속의 정보로 밀접하게 홀용할 수 있게 되었다. 즉, LBS로 인하여 GIS는 새로운 패러다임의 전환을 맞이하게 되었으며 대용량 이동체 데이터베이스 (MODB : Moving Object Database) 는 LBS를 위한 핵심 플랫폼 기능으로 인식되고 있다, 이러한 대용량 이동체 데이터베이스와 이동통신망과의 위치획득 인터페이스를 통한 위치정보 획득 기능은 아주 중요한 요소가 되며, 향후 위치를 기반으로 한 다양한 서비스가 제공될 경우, 이동성을 가지는 수많은 고객의 위치정보를 획득함으?? 심각한 시스템의 부하는 미리 예측할 수가 있다. 즉, 대용량의 이동체의 위치정보를 획득함에 있어서, 심각한 통신부하로 인한 LBS 플랫폼의 성능 저하가 발생 할 수가 있다. 따라서, MODB에서는 위치획득 기능은 안정적인 LBS플랫폼이 이동통신망으로부터 대용량의 위치정보를 획득함에 있어서, 이동체의 과거 이동 패턴을 이용하여 불필요한 위치정보 획득 회수를 줄임으로써 시스템 부하를 줄이고자 한다. 본 논문에서는 이러한 이동체의 이동 패턴을 이용하여 다양한 위치획득 모델을 설계하였으며, 시뮬레이션 환경에서 위치획득 모델을 구현함으로써 성능을 평가하였다.A가 다른 처리보다 높았다.구된다.을 나타냈다. 정소, 난소 및 자궁의 조직검사에서는 모든 투여구간에 커다란 변화는 없었다.이라는 중요성에 비추어, 사회문화주의 이론의 제안을 통해 아동의 수학 학습에서의 교사의 적극적인 역할의 가능성을 제시하고 있다. 삼림경관를 나타내었다. 각 화분대 및 아분대 우점수목의 기후환경에 대응하는 생태적 특징으로 작성한 가상 기온변화곡선의 내용은 다음과 같다: 화분대 I은 Butula우점기로서 약 57,000년 BP까지 형성되었으며, 상대적 한냉기로 간주된다. 화분대 II는 EMW우점시기로서 $57,000{\sim}43$,000년 BP에 형성되었으며, Alt Wurm에서 mittel W${\"{u}}$rm으로 전환되는 Interstadial로 간주된다. 화분대 III은 43,000~15,000년 BP간의 가장 오랜 시기를 포함하며, mittel Wurm${\sim}$Jung Wurm기에 해당한다. 한냉기인 화분대 III시기 중에는 Betula, Pinus, Picea 등의 목본류가 교대로 우점하는데, YY1에서 Quercus 와 Picea의 화분조성 변화로 볼 때 아분대 IIId시기가 가장 한냉하였을 것으로 추정된다. 화분아분대 IVa는 하부 화분대와 상부 화분대간의 전환기층으로서 피나무(Tilia)속 우점기로 나타나며, Holocene에 해당하는 화분대 IVb와 V는 약 7,000년 BP부터 현재까지 식생변화로 각각 Quercus와 Pinus가 우점하는 시기로 한국 동해안의 曺(1979)의 화분대 I과 II에 각각 대비된다. Bartlein et al.(1986)의 diagram을 통해 볼 때, 영양지역의

• 한국전자통신학회논문지
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• 제13권4호
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• pp.819-826
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• 2018

일반화된 해밍무게는 선형부호의 중요한 파라미터의 하나로써 암호시스템에 적용할 때 부호의 성능을 결정한다. 그리고 격자도를 이용하여 블록부호를 연판정으로 복호할 때 구현에 필요한 상태복잡도를 평가하는 척도가 되기도 함으로써 그 중요성이 한층 부각되고 있다. 특별히 삼항다항식을 기반으로 하는 유한체 상의 비트-병렬 곱셈기에 대한 연구가 진행되어왔다. 셀룰라오토마타(Cellular Automata, 이하 CA)는 국소적 상호작용에 의해 상태가 동시에 업데이트되는 성질이 있어서 LFSR보다 랜덤성이 우수하다. 본 논문에서는 효과적인 암호시스템 설계에 있어 중요한 요소 중 하나인 의사난수열 생성기의 효과적 합성에 관하여 다룬다. 먼저 간단한 90/150 전이규칙 블록의 특성 다항식의 성질을 분석하고, 이 규칙블록을 이용하여 삼항다항식 $x^2^n+x^{2^n-1}+1$($n{\geq}2$)에 대응하는 가역 90/150 CA와 $2^n$차 최대무게다항식에 대응하는 90/150 가역 CA(RCA)의 합성알고리즘을 제안한다.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2001년도 봄 학술발표논문집 Vol.28 No.1 (A)
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• pp.193-195
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• 2001

현대 사회는 인터넷을 통하여 수많은 정보들을 신속히 얻을 수 있고 공유할 수 있지만, 아직까지 PSTN(Public Switched Telephone Network: 공중전화망)을 이용하는 팩스가 광범위하게 사용되고 있다. 그것은 팩스가 컴퓨터 환경이 주어지지 않는 상황에서도 정보의 교환이 가능하며, 현재 팩스의 기능을 대체할 수 있는 전자메일 못지 않게 상세한 정보를 24시간 주고 받아볼 수 있기 때문이다. 그러나, 공중전화망을 이용한 팩스 전송은 LAN 환경에서의 정보 전송보다 높은 전송 비용 및 느린 전송 속도록 인하여 LAN과 PSTN을 혼용하는 인터넷 팩스 시스템이 개발되었고, 현재 상용 서비스되고 있다. 그런데, 상용 서비스를 하고 있는 인터넷 팩스 업체들은 고가의 장비와 유지/보수비용에 따른 전송 비용을 책정함으로써 공중 전화망을 이용한 전송 비용의 부담을 완전히 해소해 주지는 못하고 있다. 본 논문에서는 상용 업체들의 팩스 시스템과 서비스 형태를 분석하고, 그에 따라 전송 비용을 좀 더 절감할 수 있게 하기 위한 분산 인터넷 팩스 시스템을 설계 및 구현하였다. 즉, 상용 업체에서 제공하는 인터넷 팩스 시스템의 전송 서비스 기능의 대부분을 포함하면서, 팩스 모뎀과 LAN 환경에 연결된 PC를 사용하여 인터넷 팩스 시스템을 구축하게 함으로써 하드웨어의 구입비 및 유지/보수비용을 최소화하였을 뿐만 아니라 지역마다 팩스 서버를 분산 배치하여 별도로 운영하게 함으로써 상용 인터넷 팩스 서비스 업체들이 단독 혹은 일부 분사-지사 형태로 전송 처리해 오던 방법을 완전히 지역별로 작업을 분배 처리할 수 있게 하였다.위를 점하였다.전송과 복원이 이루어질 것이다.하지 않은 경우 단어 인식률이 43.21%인 반면 표제어간 음운변화 현상을 반영한 1-Best 사전의 경우 48.99%, Multi 사전의 경우 50.19%로 인식률이 5~6%정도 향상되었음을 볼 수 있었고, 수작업에 의한 표준발음사전의 단어 인식률 45.90% 보다도 약 3~4% 좋은 성능을 보였다.으로서 hemicellulose구조가 polyuronic acid의 형태인 것으로 사료된다. 추출획분의 구성단당은 여러 곡물연구의 보고와 유사하게 glucose, arabinose, xylose 함량이 대체로 높게 나타났다. 점미가 수가용성분에서 goucose대비 용출함량이 고르게 나타나는 경향을 보였고 흑미는 알칼리가용분에서 glucose가 상당량(0.68%) 포함되고 있음을 보여주었고 arabinose(0.68%), xylose(0.05%)도 다른 종류에 비해서 다량 함유한 것으로 나타났다. 흑미는 총식이섬유 함량이 높고 pectic substances, hemicellulose, uronic acid 함량이 높아서 콜레스테롤 저하 등의 효과가 기대되며 고섬유식품으로서 조리 특성 연구가 필요한 것으로 사료된다.리하였다. 얻어진 소견(所見)은 다음과 같았다. 1. 모년령(母年齡), 임신회수(姙娠回數), 임신기간(姙娠其間), 출산시체중등(出産時體重等)의 제요인(諸要因)은 주산기사망(周産基死亡)에 대(對)하여 통계적(統計的)으로 유의(有意)한 영향을 미치고 있어 $25{\sim}29$세(歲)의 연령군에서, 2번째 임신과 2번째의 출산에서 그리고 만삭의 임신 기간에, 출산시

• 한국게임학회 논문지
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• 제4권4호
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• pp.11-18
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• 2004

과거의 온라인 게임은 일대일 접속으로 두 사람만이 데이터를 주고받으며 게임 할 수 있었으나 현재의 온라인 게임은 MMORPG라고 해서 수만 명의 사람들이 동시에 접속이 가능하다. 특히 우리나라는 세계 어느 나라에서 찾아 볼 수 없는 네트워크 인프라를 확보하고 있다. 거의 모든 가정에 초고속 인터넷 통신망이 설치되어 있으며 높은 인구 밀도는 이런 인프라의 형성을 가속화하는 것을 가능하게 했다. 하지만 이러한 온라인 게임의 급격한 증가는 제한적인 인터넷의 통신용량에 대하여 트래픽의 증가로 이어지고 온라인 게임이 접속이 불안정해지거나 접속이 다운되는 상태로 이어질 가능성이 높다. 이러한 문제를 해결하기 위해 각 게임 서버를 보다 확충함으로서 해결할 수 있으나 그럴 경우 고비용을 필요로 하게 된다. 본 논문에서는 이러한 문제점을 해결하고자 현재의 온라인 게임에서 사용되고 있는 컨텐츠별로 나누어진 게임 서버들을 지 역 클러스터 링 형태로 연결하고, 부하 균등화(Load Balancer)서버로써 특정한 게임 서버의 부하를 감소시키고 게임 서버의 성능 향상과 효율적인 게임 서버 운용을 위하여 부하 균등화 기법을 제안한다. 본 논문에서는 그룹별 각각 다른 서비스를 하고 CPU 사용율의 자원정보를 이용하여 효율적으로 부하를 균등화하는 기법을 제안한다. 각각 서로 다른 게임을 서비스하는 그룹들은 컨텐츠들에 대한 수정, 삭제, 추가 등 자원 정보 변경으로 인하여 깨어질 수도 있는 자원 정보 일관성을 유지하기 위해 네트워크 파일 시스템에 연결되어 운영된다. 성능 실험을 통해 기존의 RR방식과 LC방식보다 제안한 방식이 각각 12%와 10%의 응답시간 향상을 보여주었다.기간효과를 별도로 취급하기는 쉽지 않다.이즈의 영향이 가장 클 것으로 판단된다. 항원성시험에서 casein으로 피하 감작할 경우 푸른색 반점이 나타났으나 효소처리구에서는 이러한 반점이 나타나지 않아 충분히 항원성이 저감화 되었음을 확인하였다. 행동을 평가하는데 있어 적정한 신뢰도와 타당도를 가지고 있었으며 임상 장면에서 아동의 행동 문제에 대한 평가 및 진단에 유용하게 사용될 수 있을 것으로 보인다.식적인 형태소-음소 상응 규칙 적용 능력 모두에서 장애를 보였으며, 거울상 반전 오류 등 시각적 정보 처리 기능의 장애도 나타내었다. 이들 장애는 단어/비단어 읽기 검사와 글자기호감별검사를 통해 신뢰할 수 있고 타당성 있게 구분하고 평가할 수 있었다.치료 시 고려해야 할 것이다.순차처리항목과 계산능력에서 유의하게 높았고(p<.05), KEDI-WISC를 이용한 평가에서는 ADHD- HI형은 대상수가 소수여서 비교할 수 없었으며, ADHD-C형과 ADHD-Ⅰ형 사이에 유의한 차이는 보이지 않았다. CPT, WCST, SST를 이용한 신경심리학적 실행기능의 비교에서 아형간 계량적인 차이는 있었으나 통계적으로 유의한 차이는 보이지 않았다. 결 론：결론적으로 ADHD 세 아형은 임상적으로 뚜렷한 차이를 보였지만, 실행기능상 유의한 차이를 발견할 수 없었다. 향후 보다 잘 고안 된 연구와 발달중인 아동에 적절한 신경심리 평가 도구의 개발을 통해 결과를 보완해야 할 것으로 사료된다.었으나, 주의력에서는 전두엽의 실행능력(executive function)과 관련되는 검사들에서 산소흡입이 특이한 효과를 보여준다는 것이 확인되었고, 기억능력에서는 단기기억능력 평가에서 산소흡입군이

• 인터넷정보학회논문지
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• 제14권6호
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• pp.71-84
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• 2013

컴퓨터 시스템 운용 간에 발생하는 많은 정보들이 기록되는 로그데이터는 컴퓨터 시스템 운용 점검, 프로세스의 최적화, 사용자 최적화 맞춤형 제공 등 다방면으로 활용되고 있다. 본 논문에서는 다양한 종류의 로그데이터들 중에서 은행에서 발생하는 대용량의 로그데이터를 처리하기 위한 클라우드 환경 하에서의 MongoDB 기반 비정형 로그 처리시스템을 제안한다. 은행업무간 발생하는 대부분의 로그데이터는 고객의 업무처리 프로세스 간에 발생하며, 고객 업무 프로세스 처리에 따른 로그데이터를 수집, 저장, 분류, 분석하기 위해서는 별도로 로그데이터를 처리하는 시스템을 구축해야만 한다. 하지만 기존 컴퓨팅환경 하에서는 폭발적으로 증가하는 대용량 비정형 로그데이터 처리를 위한 유연한 스토리지 확장성 기능, 저장된 비정형 로그데이터를 분류, 분석 처리할 수 있는 기능을 구현하기가 매우 어렵다. 이에 따라 본 논문에서는 클라우드 컴퓨팅 기술을 도입하여 기존 컴퓨팅 인프라 환경의 분석 도구 및 관리체계에서 처리하기 어려웠던 비정형 로그데이터를 처리하기 위한 클라우드 환경기반의 로그데이터 처리시스템을 제안하고 구현하였다. 제안한 본 시스템은 IaaS(Infrastructure as a Service) 클라우드 환경을 도입하여 컴퓨팅 자원의 유연한 확장성을 제공하며 실제로, 로그데이터가 장기간 축적되거나 급격하게 증가하는 상황에서 스토리지, 메모리 등의 자원을 신속성 있고 유연하게 확장을 할 수 있는 기능을 포함한다. 또한, 축적된 비정형 로그데이터의 실시간 분석이 요구되어질 때 기존의 분석도구의 처리한계를 극복하기 위해 본 시스템은 하둡 (Hadoop) 기반의 분석모듈을 도입함으로써 대용량의 로그데이터를 빠르고 신뢰성 있게 병렬 분산 처리할 수 있는 기능을 제공한다. 게다가, HDFS(Hadoop Distributed File System)을 도입함으로써 축적된 로그데이터를 블록단위로 복제본을 생성하여 저장관리하기 때문에 본 시스템은 시스템 장애와 같은 상황에서 시스템이 멈추지 않고 작동할 수 있는 자동복구 기능을 제공한다. 마지막으로, 본 시스템은 NoSQL 기반의 MongoDB를 이용하여 분산 데이터베이스를 구축함으로써 효율적으로 비정형로그데이터를 처리하는 기능을 제공한다. MySQL과 같은 관계형 데이터베이스는 복잡한 스키마 구조를 가지고 있기 때문에 비정형 로그데이터를 처리하기에 적합하지 않은 구조를 가지고 있다. 또한, 관계형 데이터베이스의 엄격한 스키마 구조는 장기간 데이터가 축적되거나, 데이터가 급격하게 증가할 때 저장된 데이터를 분할하여 여러 노드에 분산시키는 노드 확장이 어렵다는 문제점을 가지고 있다. NoSQL은 관계형 데이터베이스에서 제공하는 복잡한 연산을 지원하지는 않지만 데이터가 빠르게 증가할 때 노드 분산을 통한 데이터베이스 확장이 매우 용이하며 비정형 데이터를 처리하는데 매우 적합한 구조를 가지고 있는 비관계형 데이터베이스이다. NoSQL의 데이터 모델은 주로 키-값(Key-Value), 컬럼지향(Column-oriented), 문서지향(Document-Oriented)형태로 구분되며, 제안한 시스템은 스키마 구조가 자유로운 문서지향(Document-Oriented) 데이터 모델의 대표 격인 MongoDB를 도입하였다. 본 시스템에 MongoDB를 도입한 이유는 유연한 스키마 구조에 따른 비정형 로그데이터 처리의 용이성뿐만 아니라, 급격한 데이터 증가에 따른 유연한 노드 확장, 스토리지 확장을 자동적으로 수행하는 오토샤딩 (AutoSharding) 기능을 제공하기 때문이다. 본 논문에서 제안하는 시스템은 크게 로그 수집기 모듈, 로그 그래프생성 모듈, MongoDB 모듈, Hadoop기반 분석 모듈, MySQL 모듈로 구성되어져 있다. 로그 수집기 모듈은 각 은행에서 고객의 업무 프로세스 시작부터 종료 시점까지 발생하는 로그데이터가 클라우드 서버로 전송될 때 로그데이터 종류에 따라 데이터를 수집하고 분류하여 MongoDB 모듈과 MySQL 모듈로 분배하는 기능을 수행한다. 로그 그래프생성 모듈은 수집된 로그데이터를 분석시점, 분석종류에 따라 MongoDB 모듈, Hadoop기반 분석 모듈, MySQL 모듈에 의해서 분석되어진 결과를 사용자에게 웹 인터페이스 형태로 제공하는 역할을 한다. 실시간적 로그데이터분석이 필요한 로그데이터는 MySQL 모듈로 저장이 되어 로그 그래프생성 모듈을 통하여 실시간 로그데이터 정보를 제공한다. 실시간 분석이 아닌 단위시간당 누적된 로그데이터의 경우 MongoDB 모듈에 저장이 되고, 다양한 분석사항에 따라 사용자에게 그래프화해서 제공된다. MongoDB 모듈에 누적된 로그데이터는 Hadoop기반 분석모듈을 통해서 병렬 분산 처리 작업이 수행된다. 성능 평가를 위하여 로그데이터 삽입, 쿼리 성능에 대해서 MySQL만을 적용한 로그데이터 처리시스템과 제안한 시스템을 비교 평가하였으며 그 성능의 우수성을 검증하였다. 또한, MongoDB의 청크 크기별 로그데이터 삽입 성능평가를 통해 최적화된 청크 크기를 확인하였다.

• 대한의용생체공학회:의공학회지
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• 제6권2호
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• pp.1-8
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• 1985

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70$\pm$1.32mmHg/min)compared to CF dialyzers(4.32$\pm$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500, 550, 570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500, 550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100, 300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3, 000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.SpO2 with Plethysmograph.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
• /
• 한국우주과학회 1993년도 한국우주과학회보 제2권2호
• /
• pp.17-17
• /
• 1993

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70${\pm}$1.32mmHg/min)compared to CF dialyzers(4.32${\pm}$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500,550,570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500,550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100,300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3,000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.