• Journal of the Korean Chemical Society
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• v.53 no.6
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• pp.717-726
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• 2009

Multivariate models were developed for the simultaneous spectrophotometric determination of copper (II), nickel (II) and zinc (II) in water with 1-(2-thiazolylazo)-2-naphthol as chromogenic reagent in the presence of Triton X-100. To overcome the drawback of spectral interferences, principal component regression (PCR) and partial least square (PLS) multivariate calibration approaches were applied. Performances were validated with several test sets, and their results were then compared. In general, no significant difference in analytical performance between PLS and PCR models. The root mean square error of prediction (RMSEP) using three components for $Cu^{2+}$, $Ni^{2+}$ and $Zn^{2+}$ were 0.018, 0.010, 0.011 ppm, respectively. Figures of merit such as sensitivity, analytical sensitivity, limit of detection (LOD) were also estimated. High reliability was achieved when the proposed procedure was applied to simultaneous determination of $Cu^{2+}$, $Ni^{2+}$ and $Zn^{2+}$ in synthetic mixture and tap water.

• Journal of the Korean association of regional geographers
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• v.21 no.1
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• pp.192-205
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• 2015

This study proposes a device for the organizational frameworks and essential (content) elements of world realms in world regional geography subject. Here, the term 'organizational framework' means the method of realms division, reasonable number and naming of realms, and approaches to reams inclusively. And the term 'essential elements' designate the core elements as big ideas that every student must study through world reams. To approach these thesis, the author suggests that there is a growing trend of a combined regional concept to apply for reams division, that it is necessary to rationalize the number of realms and to prepare rather a synthetic approach to realms than a single one. And then, the author presents five essential elements as big ideas of world reams that composed of four by thematic approach and one by global-issue approach. But, this study emphasizes that in organizing the essential elements for a realm it is a better strategy to bring elements selectively with a realm because certain element fulfils function specially to certain realm.

• The KIPS Transactions:PartD
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• v.13D no.5 s.108
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• pp.633-640
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• 2006

Spatial clustering, which groups similar objects based on their distance, connectivity, or their relative density in space, is an important component of spatial data mining. Density-based and grid-based clustering are two main clustering approaches. The former is famous for its capability of discovering clusters of various shapes and eliminating noises, while the latter is well known for its high speed. Clustering large data sets has always been a serious challenge for clustering algorithms, because huge data set would make the clustering process extremely costly. In this paper, we propose an enhanced Density-Grid based Clustering algorithm for Large spatial database by setting a default number of intervals and removing the outliers effectively with the help of a proper measurement to identify areas of high density in the input data space. We use a density threshold DT to recognize dense cells before neighbor dense cells are combined to form clusters. When proposed algorithm is performed on large dataset, a proper granularity of each dimension in data space and a density threshold for recognizing dense areas can improve the performance of this algorithm. We combine grid-based and density-based methods together to not only increase the efficiency but also find clusters with arbitrary shape. Synthetic datasets are used for experimental evaluation which shows that proposed method has high performance and accuracy in the experiments.

• Geophysics and Geophysical Exploration
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• v.1 no.1
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• pp.49-56
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• 1998

Seismic tomography has been widely used as high resolution subsurface imaging techniques in engineering applications. Although most of the techniques have been using travel time inversion, waveform method is being driven forward owing to the progress of computational environments. Although full-waveform inversion method has been known as the best method in terms of model resolving power without high-frequency restriction and weak scattering approximation, it has practical disadvantage that it is apt to get stuck in local minimum if the initial guess is far from the actual model and it consumes so much time to calculate. In this study, 2-D full-waveform inversion algorithm in acoustic medium is developed, which uses result of traveltime tomography as initial model. From the application on synthetic data, it is proved that this approach can efficiently reduce the problem of conventional approaches: our algorithm shows much faster convergence rate and improvement of model resolution. Result of application on physical modeling data also shows much improvement. It is expected that this algorithm can be applicable to real data.

• Biomolecules & Therapeutics
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• v.27 no.5
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• pp.492-501
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• 2019

Nitrogen-containing heterocycles such as quinoline, quinazolinones and indole are scaffolds of natural products and have broad biological effects. During the last years those structures have been intensively synthesized and modified to yield new synthetic molecules that can specifically inhibit the activity of dysregulated protein kinases in cancer cells. Herein, a series of newly synthesized isoquinolinamine (FX-1 to 8) and isoindoloquinazolinone (FX-9, FX-42, FX-43) compounds were evaluated in regards to their anti-leukemic potential on human B- and T- acute lymphoblastic leukemia (ALL) cells. Several biological effects were observed. B-ALL cells (SEM, RS4;11) were more sensitive against isoquinolinamine compounds than T-ALL cells (Jurkat, CEM). In SEM cells, metabolic activity decreased with $10{\mu}M$ up to 26.7% (FX-3), 25.2% (FX-7) and 14.5% (FX-8). The 3-(p-Tolyl) isoquinolin-1-amine FX-9 was the most effective agent against B- and T-ALL cells with IC50 values ranging from 0.54 to $1.94{\mu}M$. None of the tested compounds displayed hemolysis on erythrocytes or cytotoxicity against healthy leukocytes. Anti-proliferative effect of FX-9 was associated with changes in cell morphology and apoptosis induction. Further, influence of FX-9 on PI3K/AKT, MAPK and JAK/STAT signaling was detected but was heterogeneous. Functional inhibition testing of 58 kinases revealed no specific inhibitory activity among cancer-related kinases. In conclusion, FX-9 displays significant antileukemic activity in B- and T-ALL cells and should be further evaluated in regards to the mechanisms of action. Further compounds of the current series might serve as templates for the design of new compounds and as basic structures for modification approaches.

• Journal of Korea Water Resources Association
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• v.55 no.spc1
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• pp.1211-1222
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• 2022

Abnormal condition inevitably occurs during operation of water distribution system (WDS) and requires the isolation of certain areas using isolation valves. In general, the determination of the optimal location of isolation valves considered minimization of hydraulic failures as isolation of certain areas causes a change in hydraulic states (e.g., flow direction, velocity, pressure, etc.). Water quality failure can also be induced by changes in hydraulics, which have not been considered for isolation valve system design. Therefore, this study proposes a new isolation valve system design methodology to prevent unexpected water quality failure events. The new methodology considers flow direction change ratio (FDCR), which accounts for flow direction changes after isolation of the area, as a constraint while reliability is used as the objective function. The optimal design model has been applied to a synthetic grid network and the results are compared with the traditional design approach. Results show that considering FDCR can eliminate flow direction changes while average pressure and coefficient of variation of pressure, velocity, and hydraulic geodesic index (HGI) outperform compared to the traditional design approach. The proposed methodology is expected to be a useful approach to minimizing unexpected consequences by traditional design approaches.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2021.05a
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• pp.43-45
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• 2021

The short-term quantitative precipitation prediction (QPF) system is important socially and economically to prevent damage from severe weather. Recently, many studies for short-term QPF model applying the Deep Neural Network (DNN) has been conducted. These studies require the sophisticated pre-processing because the mistreatment of various and vast meteorological data sets leads to lower performance of QPF. Especially, for more accurate prediction of the non-linear trends in precipitation, the dataset needs to be carefully handled based on the physical and dynamical understands the data. Thereby, this paper proposes the following approaches: i) refining and combining major factors (weather radar, terrain, air temperature, and so on) related to precipitation development in order to construct training data for pattern analysis of precipitation; ii) producing predicted precipitation fields based on Convolutional with ConvLSTM. The proposed algorithm was evaluated by rainfall events in 2020. It is outperformed in the magnitude and strength of precipitation, and clearly predicted non-linear pattern of precipitation. The algorithm can be useful as a forecasting tool for preventing severe weather.

• The Journal of the Acoustical Society of Korea
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• v.25 no.5
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• pp.213-221
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• 2006

Phone segmentation of speech waveform is especially important for concatenative text to speech synthesis which uses segmented corpora for the construction of synthetic units. because the quality of synthesized speech depends critically on the accuracy of the segmentation. In the beginning. the phone segmentation was manually performed. but it brings the huge effort and the large time delay. HMM-based approaches adopted from automatic speech recognition are most widely used for automatic segmentation in speech synthesis, providing a consistent and accurate phone labeling scheme. Even the HMM-based approach has been successful, it may locate a phone boundary at a different position than expected. In this paper. we categorized adjacent phoneme pairs and analyzed the mismatches between hand-labeled transcriptions and HMM-based labels. Then we described the dominant error patterns that must be improved for the speech synthesis. For the experiment. hand labeled standard Korean speech DB from ETRI was used as a reference DB. Time difference larger than 20ms between hand-labeled phoneme boundary and auto-aligned boundary is treated as an automatic segmentation error. Our experimental results from female speaker revealed that plosive-vowel, affricate-vowel and vowel-liquid pairs showed high accuracies, 99%, 99.5% and 99% respectively. But stop-nasal, stop-liquid and nasal-liquid pairs showed very low accuracies, 45%, 50% and 55%. And these from male speaker revealed similar tendency.

• Nuclear Engineering and Technology
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• v.56 no.3
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• pp.803-811
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• 2024

Nuclear accidents such as Fukushima Daiichi have highlighted the potential of passive safety systems to replace or complement active safety systems as part of the overall prevention and/or mitigation strategies. In addition, passive systems are key features of Small Modular Reactors (SMRs), for which they are becoming almost unavoidable and are part of the basic design of many reactors available in today's nuclear market. Nevertheless, their potential to significantly increase the safety of nuclear power plants still needs to be strengthened, in particular the ability of computer codes to determine their performance and reliability in industrial applications and support the safety demonstration. The PASTELS project (September 2020-February 2024), funded by the European Commission "Euratom H2020" programme, is devoted to the study of passive systems relying on natural circulation. The project focuses on two types, namely the SAfety COndenser (SACO) for the evacuation of the core residual power and the Containment Wall Condenser (CWC) for the reduction of heat and pressure in the containment vessel in case of accident. A specific design for each of these systems is being investigated in the project. Firstly, a straight vertical pool type of SACO has been implemented on the Framatome's PKL loop at Erlangen. It represents a tube bundle type heat exchanger that transfers heat from the secondary circuit to the water pool in which it is immersed by condensing the vapour generated in the steam generator. Secondly, the project relies on the CWC installed on the PASI test loop at LUT University in Finland. This facility reproduces the thermal-hydraulic behaviour of a Passive Containment Cooling System (PCCS) mainly composed of a CWC, a heat exchanger in the containment vessel connected to a water tank at atmospheric pressure outside the vessel which represents the ultimate heat sink. Several activities are carried out within the framework of the project. Different tests are conducted on these integral test facilities to produce new and relevant experimental data allowing to better characterize the physical behaviours and the performances of these systems for various thermo-hydraulic conditions. These test programmes are simulated by different codes acting at different scales, mainly system and CFD codes. New "system/CFD" coupling approaches are also considered to evaluate their potential to benefit both from the accuracy of CFD in regions where local 3D effects are dominant and system codes whose computational speed, robustness and general level of physical validation are particularly appreciated in industrial studies. In parallel, the project includes the study of single and two-phase natural circulation loops through a bibliographical study and the simulations of the PERSEO and HERO-2 experimental facilities. After a synthetic presentation of the project and its objectives, this article provides the reader with findings related to the physical analysis of the test results obtained on the PKL and PASI installations as well an overall evaluation of the capability of the different numerical tools to simulate passive systems.

• Korean Journal of Remote Sensing
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• v.36 no.5_3
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• pp.1109-1123
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• 2020

In South Korea with forest as a major land cover class (over 60% of the country), many wildfires occur every year. Wildfires weaken the shear strength of the soil, forming a layer of soil that is vulnerable to landslides. It is important to identify the severity of a wildfire as well as the burned area to sustainably manage the forest. Although satellite remote sensing has been widely used to map wildfire severity, it is often difficult to determine the severity using only the temporal change of satellite-derived indices such as Normalized Difference Vegetation Index (NDVI) and Normalized Burn Ratio (NBR). In this study, we proposed an approach for determining wildfire severity based on machine learning through the synergistic use of Sentinel-1A Synthetic Aperture Radar-C data and Sentinel-2A Multi Spectral Instrument data. Three wildfire cases-Samcheok in May 2017, Gangreung·Donghae in April 2019, and Gosung·Sokcho in April 2019-were used for developing wildfire severity mapping models with three machine learning algorithms (i.e., Random Forest, Logistic Regression, and Support Vector Machine). The results showed that the random forest model yielded the best performance, resulting in an overall accuracy of 82.3%. The cross-site validation to examine the spatiotemporal transferability of the machine learning models showed that the models were highly sensitive to temporal differences between the training and validation sites, especially in the early growing season. This implies that a more robust model with high spatiotemporal transferability can be developed when more wildfire cases with different seasons and areas are added in the future.