• 한국운동역학회지
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• 제30권2호
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• pp.131-144
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• 2020

Objective: The purpose of this study was to examine the effect of degrees of freedom on the multi-synergies in two hierarchies of human hand system during force production and releasing tasks. Method: In this study, the constrained movements of the aiming and releasing actions using both hands and fingers during archery-like shooting were implemented as experimental tasks. The participants produced a pulling force holding the customized frame (mimicking an archery bow, with a set of force transducers) and kept it consistently for about 5 seconds, and released fingers as quickly as possible in a self-paced manner within the next 5 seconds. An analytical method based on the uncontrolled manifold hypothesis was used to quantify the stability index (synergy index) in two hierarchies including two hands (upper hierarchy) and individual fingers (lower hierarchy). Results: The results confirmed that the positive synergy pattern showed simultaneously at the upper and lower hierarchies, and the kinetic degrees of freedom were associated with the increment of hierarchical synergy indices and the performance indices. Also, the synergy indices of both hierarchies showed significant positive correlations with the performance accuracy during the task. Conclusion: The results of this study suggest that the human control system actively uses extra degrees of freedom to stabilize task performance variables. Further increasing the degree of freedom at one level of hierarchy induces positive interactions across hierarchical control levels, which in turn positively affects the accuracy and precision of task performance.

• 한국전문물리치료학회지
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• 제29권2호
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• pp.147-155
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• 2022

Background: Although various conventional approaches have been employed to reduce spasticity in neurological rehabilitation, only a few studies have shown scientific evidence for its effectiveness. Thus, we introduced a different concept (Ueda method) of rehabilitation therapy that can complement the limitations of conventional therapy. Objects: This study aimed to investigate the immediate effects of the application of the Ueda method on patients with spasticity after stroke via an electrophysiological study. Methods: We conducted a randomized double-blind pilot study in two rehabilitation hospitals involving 30 stroke patients who were randomly allocated to the Ueda (n = 15) and convention (n = 15) groups. Electromyographic data of six examined muscles in both upper extremities of all patients were recorded. The A-ApA index and activation ratios of upper extremity muscles were evaluated and compared between the groups to confirm post-intervention changes in upper-extremity flexor spasticity and flexion synergies. Repeated-measures analysis of variance was conducted to confirm the therapeutic effect (2 × 2) as a function of group (Ueda vs. convention) and time (pre-/post-intervention) on all outcome measures (p < 0.05). Results: In the Ueda group, the mean A-ApA index values differed significantly before and after the intervention (p = 0.041), indicating a weak evidence level; however, the effect size was medium (d = -0.503). The interaction effects of the A-ApA index between the Ueda and convention groups and between pre-intervention and post-intervention stages were significant (p = 0.012). The effect size was large (n_p² = 0.220). In the Ueda group, the activation ratios of the anterior deltoid fiber significantly decreased after the intervention in all reaching tasks. Conclusion: The Ueda method reduces upper-extremity flexor spasticity and changes its synergy in stroke patients and should be considered a rehabilitation therapy for spastic stroke patients.

• IMMUNE NETWORK
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• 제24권2호
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• pp.14.1-14.26
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• 2024

The inflammatory response during cutaneous leishmaniasis (CL) involves immune and non-immune cell cooperation to contain and eliminate Leishmania parasites. The orchestration of these responses is coordinated primarily by CD4⁺ T cells; however, the disease outcome depends on the Th cell predominant phenotype. Although Th1 and Th2 phenotypes are the most addressed as steers for the resolution or perpetuation of the disease, Th17 cell activities, especially IL-17 release, are recognized to be vital during CL development. Th17 cells perform vital functions during both acute and chronic phases of CL. Overall, Th17 cells induce the migration of phagocytes (neutrophils, macrophages) to the infection site and CD8⁺ T cells and NK cell activation. They also provoke granzyme and perforin secretion from CD8⁺ T cells, macrophage differentiation towards an M2 phenotype, and expansion of B and Treg cells. Likewise, immune cells from the inflammatory infiltrate have modulatory activities over Th17 cells involving their differentiation from naive CD4⁺ T cells and further expansion by generating a microenvironment rich in optimal cytokines such as IL-1β, TGF-β, IL-6, and IL-21. Th17 cell activities and synergies are crucial for the resistance of the infection during the early and acute stages; however, if unchecked, Th17 cells might lead to a chronic stage. This review discusses the synergies between Th17 cells and the inflammatory infiltrate and how these interactions might destine the course of CL.

• 패션비즈니스
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• 제3권1호
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• pp.138-146
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• 1999

For an enterprise to survive in extremely competitive world, it had better to down budget and resource of unimportant fields so that the enterprise can concentrate resources on the strong field. Nowadays in Korea, it is important to research outsourcing for strengthen the competitive power in apparel maker because of recent depression. The questionnaire was composed of 14 factors about outsourcing effect. The questionnaires were selected for finial analysis 67 apparel makers in Pusan and Seoul and data was analysed by using paired t-test by SPSS program. Almost of apparel makers (85.07%) has been outsourced the sewing process to contractor or vendor. Outsourcing in this case is marked lower effect than insourcing except reducing cost, economy of time and overcoming internal resources. This means that our outsourcing has been progressed with so many risk. If we have research the successful outsourcing and have a strategic vision and plan with vendor and product mutually beneficial relationship, we can share the risk and creating new business synergies through outsourcing.

• 한국농공학회논문집
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• 제54권6호
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• pp.1-8
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• 2012

To increase the synergies of rural experience tourism and overcome the limitations rural tourism are study. A basic cooperative model and theme model have been set up and comprehensive cooperative tourism model has been offered. In order to the development of model example, experience resources has been investigated and problems and features for 7 rural experience tourism villages of Cheongwon have been identified. The basic cooperative model has been selected main line and part hub type. The theme model has been separated nature experience, history and character experience, traditional culture and theme experience, agriculture and rural area experience. Based on this, The thematic cooperative tourism model and the comprehensive cooperative tourism model, its a schedule have been exemplified.

• Journal of Ecology and Environment
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• 제33권4호
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• pp.271-274
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• 2010

The Ministry of Environment of South Korea has launched its plan to establish the National Ecological Institute. An International Symposium and Workshop was held at Ewha Womans University in Seoul on Thursday, 30 September 2010, to strengthen international cooperation, networking and partnerships for the conservation of biodiversity. This symposium was attended by experts of many major institutions for biodiversity conservation from South Korea and overseas. At the symposium and workshop preceded by a keynote speech by the renowned primatologist and conservation biologist Jane Goodall the participants discussed a wide range of topics including "biodiversity conservation: in situ and ex situ approaches", "conservation of species diversity and ecosystem management", and "international cooperation for biodiversity conservation and research". As a basis for future discussions, this article summarizes how the National Ecological Institute might contribute most effectively to public life and environmental management in South Korea and worldwide. It addresses the following issues: governance and funding, synergies within Korea, participation in international networks, external advice, a broad view of ecological issues, research agenda, building on identity, public outreach, and training the next generation of scientists.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2014년도 춘계 학술논문 발표대회
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• pp.190-191
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• 2014

Recent construction sector integration and fusion technologies in various areas of research and planning systemis being maintained by the system. Past experience of conservative management in this emerging technology-driven business management through the convergence of various technologies and to find synergies to secure the future of construction technology because it is a need. The purpose of this study is builton the basis of technical and Technology Management Contact optimized system for integrated management of the area you want to build.

• 전자공학회지
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• 제24권2호
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• pp.13-26
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• 1997

Throughout the world in major urban centers, the volume of vehicular traffic on roads continues to increase. ITS provides drivers with traffic information and new routing options on route In order to make them move quickly to their destinations. The higher mobility, the more productivity we gain. The ultimate goal of Intelligent Transport System is to improve mobility. ITS world is broad and quite varied, as demonstrated by ITS user services, their distinct needs, and complex Interactions and synergies. ITS ties the transportation and telecommunication worlds together. The complex world of telecommunications is evolving and expanding rapidly. Especially over the last two decades, the birth and unprecedented growth of wireless is really marvelous and further holds tremendous promise into the future. This wireless and emerging technologies will offer extensive opportunities to handle many ITS user services, and alter many of the traditional paradigms of transportation.

• International Journal of Quality Innovation
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• 제2권1호
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• pp.87-105
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• 2001

More than a decade after their development and first wave of deployment, Six Sigma and Lean Manufacturing have recently returned on the corporate agendas of a larger number of corporations across industries and supply chains. In the wake of their re-surge, this commentary addresses the evolution, context, content and deployment patterns of the two distinct management concepts. It also analyses claims in the business press that a merger is taking place between Six Sigma and Lean Manufacturing. Here, it is found that there is not enough evidence to broadly support such claims, and it is only concluded that there is some evidence of an early tend towards a merger and that a possible merger would have many synergies and advantages. Finally, an example from a Scandinavian manufacturing company is provided that explains how Six Sigma and Lean Manufacturing can be used in a beneficial way for companies to reach world-class performance.

• International journal of advanced smart convergence
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• 제10권4호
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• pp.172-182
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• 2021

We look at the business model development of a fan community platform 'Weverse' from two-sided platform (TSP) to multi-sided platform (MSP) and investigate its platform business model. From the Rocket Model's theoretical perspective, the results reveal that Weverse firstly focuses on inviting artists as many as possible starting from BTS, then attracts new artists' fans naturally. For success of this TSP, it forms MSP, 'Weverse Shop' to meet two sides' relevant needs timely and filtered. In third stage of connection, various partnerships are attempted in terms of open platform strategies. For instance, by combining 'VLive' and Weverse, Naver's fan platform business is transferred to Weverse. For core transaction through direct and indirect monetization, several cobranding activities are tried. Lastly, regarding optimization, newly born Weverse being launched in the first half of 2022 is supposed to create further synergies with Naver's R&D capabilities in data, AI, and other technologies like metaverse platform 'ZEPETO' which already sells clothing items of Weverse artists.