• 생명과학회지
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• 제9권6호
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• pp.704-708
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• 1999

This research was carried out for evaluating diagnostic value of antibody test in Fragile X syndrome. In antibody test of control individuals and carriers with a premutation, FMRP were detected in the lymphocytes, whereas the lymphocytes of male Fragile X syndrome patients were devoid of FMRP. Five Fragile X syndrome male patient, two Fragile X syndrome female patients, three carriers were diagnosed by southern blot. Five boys who were diagnosed as the patients by antibody test were turned out full mutation and having multiple smear beside normal single band. However, fragile site of X chromosome was not expressed in Fragile X syndrome patients by chromosome analysis. These results showed that antibody test was a fast and simple method, but the diagnostic power was "perpect" for males, whereas the results were less specific for females.r females.

• 동의생리병리학회지
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• 제19권5호
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• pp.1191-1194
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• 2005

The aim of this study was to investigate the change of Heart Rate Variability(HRV) that mild cold stimulus on the forehead of healthy men induces. 34 healthy male subjects participated in the experiments. On the first test series, 15 subjects were applied to the mild cold stimulus by the devise for cold stimulation. In the second test series, 10 subjects With heat Syndrome and 5 subjects With cold Syndrome were applied to the mild cold Stimulus. Aa a additional test, 4 subjects with cold syndrome were applied to the warm stimulus in the last test series. We analyzed the HRV through measuring electrocardiogram.(ECG). The result of this study is comparatively clear. In the first test series, mild cold stimulus made parasympathetic nervous system be activated. In the second test series, mild cold stimulus made parasympathetic nervous system be activated both in subjects with heat syndrome and subjects with cold syndrome, and heat syndrome shows more active parasympathetic nervous system rather than cold syndrome subjects do. In the last test series, 2 subjects with cold syndrome respond the mild cold stimulus. That means warm stimulus of cold condition subjects made parasympathetic nervous system active in 2 of 4 subjects. We found out that mild cold stimulus on forehead makes parasympathetic nervous system be activated in healthy male, and it can be interpreted that mild cold stimulus make healthy human be relaxed. Also, subjects have different fondness of thermal stimulus according to their Cold or Heat condition Preferences. Last test series shows that we need to investigate effect of the warm stimulus heat syndrome subjects.

• Journal of Genetic Medicine
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• 제5권1호
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• pp.7-14
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• 2008

Twenty years have passed since a prenatal screening for Down syndrome and neural tube defect was applied to obstetric field. The Quad test (AFP, hCG, uE3, Inhibin-A) of the second trimester and the combination test (PAPP-A, hCG, NT) of the first trimester became popular now. The recent trend of prenatal screening is to combine these two screening tests together in order to increase a detection rate of Down syndrome. Three types of screening methods are introduced as follows; integrated test, sequential test and contingent test. In addition to combination of each test, an incorporation of characteristic ultrasound findings of Down syndrome is suggested for its risk calculation. The absence of fetal nasal bone would be a very useful marker especially in the first trimester screening test. According to a change of way calculating risk of Down syndrome, obstetrician's role will be more increased not by passive participation, but by active participation using ultrasound in risk calculation.

• 대한한방내과학회지
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• 제20권1호
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• pp.274-279
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• 1999

In order to look about the effect and possibility of oriental medical diagnosis and treatment of pancytopenia of myelodysplastic syndrome. For a patient who has pancytopenia. we diagnose him as myelodysplastic syndrome by CBC, LFT, Ultrasonic wave, Vitamin B12 test, Bone marrow test, Folic acid test and doing Herb-medication, Moxa-Tx continually, we observed the change of WBC, RBC. HGB. MCV, Platelet. ESR with following up CBC test ten times Finally, WBC increased by 900, RBC increased by 400000, MCV was reduced by 7fl. HGB increased by 1.3g/dl. Hct increased by 3.2%, ESR was reduced from 127 to 35mm/h. We diagnosed myelodysplastic syndrome as 'CONSUMPTIVE DISEASE' in oreintal medicine. The treatment effect of pancytopenia was achieved by Herb-medication and Moxa-Tx for invigorating qi, enriching the blood, invigorating the spleen and the kidney-yang, Now we need the study of oriental medical treatment for Aplastic Anemia and AML which is similar this.

• Physical Therapy Rehabilitation Science
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• 제11권4호
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• pp.553-564
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• 2022

Objective: The purpose of this studyaimed to investigate the effects of scapular stabilization training using the different exercise prop for impingement syndrome of factory workers. Design: A randomized controlled trial Methods: Twenty shoulder impingement syndrome subjects were randomly divided into two groups of ten subjects each. Inclusion criteria was presence of positive sign in at least two of Neer test, Hawkins test, Yocum test, Jobe test and Speeds test. Andexclusion criteria, those with surgical history of rotator cuff, those with disease in upper limb other than shoulder impingement syndrome, those who took anti-inflammatory drugs over the past 12 months were excluded from the sample. One group was performed scapula stabilization exercise using elastic bands, while dumbbell group performed the exercise using dumbbell. Both groups performed the exercise after applying the general physical therapy. After applying five days a week for a total of six weeks, range of motion of shoulder joint, muscle strength and pain and function level were evaluated. Results: After the intervention, in both groups, all dependent variables at the 6-week post-test significantly improved compared with the pre-test (p<0.05). In addition, elastic band exercise group showed a significant differences in SPADI function score and SPADI total score compared to the dumbbell group(p<0.05). Conclusions: The elastic band training may be effective methodology using low-to-moderate intensity resistance for SPADI scores.

• 대한두경부종양학회지
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• 제32권1호
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• pp.1-5
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• 2016

Objectives: Frey's syndrome is an infrequent complication after parotidectomy and its incidence varies from 23.5% to 50.8% in the literature. The objective of this study was to evaluate the actual incidence and clinical characteristics of Frey's syndrome. Methods: We analyzed 31 patients who underwent parotidectomy and serial Minor's starch-iodine test. The mean follow-up period was $66{\pm}26.1$ months (range, 24-118 months). The Frey's syndrome was analyzed using a questionnaire for the assessment of the subjective symptom and Minor's starch-iodine test for the objective measurement at 1, 3, 6, and 12 months after the surgery and then every 6 or 12 months. Minor's starch-iodine test was graded from 0 to 3 according to the area of discolorization. Results: Frey's syndrome occurred in 11 patients (35.5%) on the Minor's starch-iodine test. The mean onset of Frey's syndrome on the starch-iodine test was $13.6{\pm}10.4$ months after parotidectomy. Sixteen patients (51.6%) complained about gustatory sweating and flushing. The onset of the subjective symptom was $11.27{\pm}6.96$ months after the surgery. There was a significant correlation between the grade of the starch-iodine test and the severity of subjective symptoms (P <0.001). Various factors including size and location of tumor, incision method, and extent of parotidectomy did not correlate with the Frey's syndrome. Conclusion: The incidence of Frey's syndrome was 35.5% on the Starch-Iodine test, and the onset was about postoperative 13.6 months.

• 한국보건간호학회지
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• 제28권2호
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• pp.270-284
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• 2014

Purpose: This study investigated the effects of lifestyle factors in metabolic syndrome among adolescents. The metabolic syndrome has been reported as a cause of various chronic diseases, including cardiovascular disease and diabetes in adolescents. Method: This study is a cross-sectional study on 1,931 adolescents (1,011 boys and 920 girls) aged 12-19 years from the Korean Health and Nutrition Examination Survey 2010-2012. Data were analyzed by descriptive statistics, t-test, $x^2$-test, and logistic regression in consideration of strata, cluster, and weight as national data. Result: The prevalence of metabolic syndrome in adolescents aged 12-19 years was 4.3% (Boys, 5.4%; Girls, 3.1%). Among lifestyle factors, BMI had significants influences on the metabolic syndrome risk, but other variables did not. Conclusion: The results of this study indicate that further research is necessary on the effect of lifestyle factors in metabolic syndrome and that school health nurses should focus on implementation of effective programs for promotion of activity and healthy foods for prevention and intervention of metabolic syndrome.

• 대한추나의학회지
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• 제2권1호
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• pp.43-50
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• 2001

Objectives : Scalenus anticus syndrome and Piriformis syndrome is representative of myogenic Nerve entrapment syndrome, and their clinical symptoms are similar to HIVD(herniated Intervertebral disc) of cervical or lumbar spine. But, distinguished by muscle test, these syndrome apply to Meridian-muscle therapy. Methods : Meridian-muscle therapy consists of Ashi(阿是)-point therapy, taping therapy, myofascial release technique, manipulation, their based on the traditional meridian-muscle theory. This theory is similar to myofascial pain syndrome in western medicine. The study population consisted of 9 patients who were already diagnosed as Nerve entrapment syndrome with radiological examination & physical examination and muscle test. The evaluation of clinical outcome was done by Visual Analogue Scale (VAS) and Pain Assesment Questionnaire(PAQ). Results and Conclusions : After treatment, All patient's VAS is decreased as $2.11{\pm}1.59$ and the evaluation of clinical effect was excellent(6 cases) or good(3 cases) according to PAQ. Conclusively, Meridian muscle therapy is efficacious against Nerve entrapment syndrome.

• Archives of Reconstructive Microsurgery
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• 제24권1호
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• pp.13-15
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• 2015

Purpose: Since the hand elevation test was first introduced by Ahn in 2001, it has been one of most performing provocative test for diagnosing carpal tunnel syndrome. Although many studies have been published on the hand elevation test, there are no study that can explain why false-negative results of hand elevation test appears in carpal tunnel syndrome patients diagnosed by electromyography (EMG) findings. Therefore we searched out whether hand elevation test is related with EMG severity. Materials and Methods: We made a retrospective study of 654 bilateral carpal tunnel syndrome patients. Among them 134 were studied which had different hand elevation test results on each hands. The paired samples t-test was used to compare the EMG severity of each group. The relationships between hand elevation test and EMG severity were examined using Pearson-product correlations. Comparing whether the frequency of false negative hand elevation were different between both hands, and whether the severity of EMG depends on which side of hand is, was evaluated with Mann-Whitney U-test. Results: Severity of EMG in positive group was moderate to severe on average, whereas mild to moderate on negative group, with significant difference statistically (p<0.001). Correlation between the hand elevation test results and EMG severity also showed significance statistically (p<0.001). Conclusion: Mild severity of EMG was found out to be the factor affecting the false results. However, EMG severity and hand elevation test shows a meaningful correlation, supporting the value of hand elevation test.

• 지역사회간호학회지
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• 제19권3호
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• pp.495-505
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• 2008

Purpose: This study was conducted to identify the relation between farmers' syndrome and the quality of life of residents in suburban areas. Methods: A total of 994 subjects were selected through simple random sampling. Data were collected from June 25 to August 31, 2007. Data analysis included frequency, $X^2$-test, Fisher's exact test, t-test, ANOVA, Duncan test, and Pearson's correlation coefficient using SPSS Win 12.0. Results: 1. Analysis of farmers' syndrome showed that there were statistically significant differences according to age, gender, education, living with, family conversation, health security, monthly income, occupation, general health status, systolic blood pressure, and sleeping time. 2. Analysis of the qualify of life showed that there were statistically significant differences according to age, education, religion, family conversation, health security, monthly income, occupation, and sleeping time. 3. Farmers' syndrome was in a significantly negative correlation with quality of life. Conclusions: Considering the results above, we need to develop nursing interventions for decreasing hypertension, high blood sugar, and farmers' syndrome of residents in suburban area.