• 대한한방소아과학회지
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• 제27권3호
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• pp.1-11
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• 2013

Objectives The purpose of this study is to evaluate the characteristics of autonomic nervous system in heart-weakened children via analyzing heart rate variability (HRV) compare to healthy children. Methods Among the children who have visited the department of pediatrics at OO oriental medicine hospital, the subjects were composed of 62 elementary school students without cardiac disorder, who have yet develop secondary sexual characteristics. Results 1. Mean HRT and SDNN of the heart-weakened group of children were lower than the healthy group, but with no statistical significance. 2. Heart-weakened children had higher LF norm and LF/HF ratio, but lower HF norm than healthy children. The rest of the Frequency Domain Index have no significant differences. 3. Heart-weak score showed a positive correlation with Mean HRT and LF/HF ratio. Conclusions Heart-weakened children had an imbalance in autonomic nervous system due to increase of sympathetic nerve activity and decrease of parasympathetic nerve activity.

• 척추신경추나의학회지
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• 제4권2호
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• pp.47-60
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• 2009

Objectives : The purpose of this study is to investigate the effect of chuna treatment on cervical sprain caused by traffic accident in early stage. Methods : This study carried out on 20 patients who have received hospital treatment in Daejeon Univ. cheonan Oriental Hospital. Non-chuna group got acupunture-therapy, herbal medication, physical therapy and Chuna group got chuna treatment besides. We measured Heart Rate Variability(HRV) and Visual Analog Scale(VAS) on 2nd, 4th day. Results : After being treated by our methods, Chuna Group showed the inclination to balance the sympathetic and parasympathetic nerve. In chuna group, an autonomic nerve activity showed the inclination to increase. But there were no significant difference between both groups. Chuna group's VAS were significantly decreased(p=0.043). Conclusions : The results suggest that Chuna treatment help traffic accident patients in early stage to reduce pain. Refer to autonomic nerve system, chuna treatment seem to do positive effect but Further long tenn study in a large scale is needed.

• 대한한방내과학회지
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• 제42권5호
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• pp.1001-1008
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• 2021

목적: 국소다한증 환자의 홍채진단을 사용한 변증 및 한의 치료에 대한 연구 방법: 국소다한증을 호소하여 내원한 환자에게 한의학 기본 진단법인 사진법을 사용하여 태음인임을 진단하였다. 그리고 카메라를 사용하여 홍채를 촬영하였고, 얻어진 이미지에서 교감신경항진과 관련된 표지인 권축륜의 선명하고 굵은 모습과 다수의 신경긴장선이 존재하는 모습을 통해 교감신경이 항진되어 있음을 확인하였다. 태음인 체질방을 기본으로 교감신경 항진을 조절하는 약재를 가미한 한약처방을 1개월간 복용하도록 하였다. 결과: 다양한 치료에도 호전되지 않던 30년 가까이 된 수족 다한증이 한약치료를 통해 복약 4일차부터 감소하기 시작하여 6주 만에 치료 시작 전과 비교하여 80% 호전되었다. 결론: 만성적이고 다양한 치료에도 반응하지 않던 수족 다한증에 한약 치료가 효과적일 수 있음을 이번 연구를 통해 보고한다.

• 한국한의학연구원논문집
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• 제17권2호
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• pp.85-100
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• 2011

Objectives : This study aimed to investigate the effect of four common types of Qigong position (standing, sitting, supine, and horse-riding position) on the autonomic nervous system. Method : Thirty healthy subjects participated in this study once a week for four weeks. Heart Rate Variability (HRV) was measured three times (before, during, and after the position) while the subject maintained one of four positions for ten minutes. Result : There were significant changes HRV in the standing position. In the sitting position, both the sympathetic and parasympathetic nerves were activated. On the other hand, in the spine position, heart rate (HR) was decreased. Activation of sympathetic and parasympathetic nerves was also observed in this position. Significant increases of indices related to awakening and concentration were observed accompanied by increase of HR and a sympathetic nerve was activated in the riding-horse position. Conclusions : In the present study, it was shown that each Qigong position caused various and significant changes in autonomic nervous system. It would be expected that these results can be applied to choose appropriate Qigong position according to objective of Qigong therapy although it is remained to further evaluate the effects of long-term maintenance of Qigong positions and repeated Qigong training.

• The Korean Journal of Physiology and Pharmacology
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• 제2권3호
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• pp.287-295
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• 1998

Diazepam is known to have cardiovascular depressive effects through a combined action on benzodiazepinergic receptor and the GABA receptor-chloride ion channel complex. Moreover, it is known that barbiturates also have some cardiovascular regulatory effects mediated by the central GABAergic system. Therefore, this study was undertaken to delineate the regulatory actions and interactions of these systems by measuring the responses of the cardiovascular system and renal nerve activity to muscimol, diazepam and pentobarbital, administered intracerebroventricularly in rabbits. When muscimol $(0.03{\sim}0.3\;{\mu}\;g/kg)$, diazepam $(10{\sim}100\;{\mu}\;g/kg)$ and pentobarbital $(1{\sim}10\;{\mu}\;g/kg)$ were injected into the lateral ventricle of the rabbit brain, there were similar dose-dependent decreases in blood pressure (BP) and renal nerve activity (RNA). The relative potency of the three drugs in decreasing BP and RNA was muscimol ＞ pentobarbital ＞ diazepam. Muscimol and pentobarbital also decreased the heart rate in a dose-dependent manner; however, diazepam produced a trivial, dose-independent decrease in heart rate. Diazepam $(30\;{\mu}g/kg)$ augmented the effect of muscimol $(0.1\;{\mu}g/kg)$ in decreasing blood pressure and renal nerve activity, but pentobarbital $(3\;{\mu}g/kg)$ did not. Bicuculline $(0.5\;{\mu}g/kg)$, a GABAergic receptor blocker, significantly attenuated the effect of muscimol in decreasing BP and RNA, either alone or with diazepam, and that of pentobarbital in decreasing BP and RNA, either alone or with muscimol. We inferred that the central benzodiazepinergic and barbiturate systems help regulate peripheral cardiovascular function by modulating the GABAergic system, which adjusts the output of the vasomotor center and hence controls peripheral sympathetic tone. Benzodiazepines more readily modulate the GABAergic system than barbiturates.

• 정신신체의학
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• 제12권1호
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• pp.3-14
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• 2004

신경심장학의 발전으로 중추신경 활성이 심장의 전기적 활동도에 미치는 영향이 밝혀지고 있고, 심박동수변이(Heart rate variability, HRV)가 정신적 스트레스와 심혈관질환의 기계적 연관성을 나타내는 중요한 지표로 제기되고 있다. HRV란 자율신경계의 정상적 상호작용에 의해 나타나는 생리적인 심박수 변동을 타나내며, 자율신경 기능을 정량화하여 측정할 수 있는 방법론이다. 분석 방법은 시간 영역 분석과 주파수 영역 분석으로 나눌 수 있으며, 측정 시간대에 따라 단기간 측정과 24시간 측정 등의 방법이 확립되어 있다. 임상적으로는 변이 정도, 교감신경과 부교감신경의 활성과 균형도를 파악하여 다양한 질환과 스트레스 등의 진단과 치료 및 예후 판정에 활용되고 있다. HRV를 이용한 바이오피드백도 최근 자율신경 관련 질환의 치료에 활용되고 있다. 향후 다양한 프로토콜의 개발과 임상적 적용이 필요할 것으로 보인다.

• 척추신경추나의학회지
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• 제3권1호
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• pp.73-82
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• 2008

Objectives : This study was performed to examine the hypothesis that the structural imbalance affect cardiac function and autonomic reflex system and to investigate the possibility of the chiropractic care for cardiovascular system. Methods : 78 of Dong-Guk University students with structural imbalance were recruited for the investigation from March to June 2007. Heart rate variability, Buss and Durkee Hostility inventory(BDHI) and physical examinations to evaluate psoas muscle contracture were performed. Results : Left psoas muscle contracture was associated with decrease of LF/HF ratio(p=0.048). Conclusion : Left side contracture of psoas muscle showed a tendency to decrease sympathetic activity.

• 대한한방내과학회지
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• 제29권4호
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• pp.904-912
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• 2008

Objectives : The objective of this study was to investigate the correlation between swallowing acid symptom and autonomic nerve system in dyspepsia patients. Methods : The test for heart rate variability (HRV) was done to 50 dyspepsia patients at the Department of Internal Medicine, Kang-Nam Kyung-Hee Korean Hospital. 21 among 50 patients had swallowing acid symptom and 29 didn't. We checked HRV and compared HRV index between the two groups. We also divided the patients into functional dyspepsia and organic dyspepsia groups, and then checked HRV respectively. Results were as follows : 1. In dyspepsia patients with swallowing acid, LF/HF ratio was higher than the dyspepsia patients without swallowing acid but the result was not statistically significant. 2. TP, LF, VLF, and LF/HF ratio was higher in the functional dyspepsia group than in the organic dyspepsia group. Average age in the organic dyspepsia group was significantly higher than in the other group. Both results showed statistically significant difference. 3. In the functional dyspepsia group, LF/HF ratio was significantly higher in patients with swallowing acid symptom than those without. However, in eructation and nausea symptoms, HRV index was not statistically significant. Conclusion : This study shows the ratio of sympathetic and parasympathetic nerve system increased in the swallowing acid patient group compared with the non-swallowing acid patient group in functional dyspepsia patients.

• 대한의료기공학회지
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• 제15권1호
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• pp.89-108
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• 2015

Objects : the relationship between the body changes in microgravity and Su-Seung-Hwa-Gang(body water rising and heat falling) in Korean medicine. Methods : research of papers about the body changes in microgravity and Su-Seung-Hwa-Gang in Korean medicine. Conclusions : In microgravity, there are changes in cardiovascular system and sympathetic nerve system(SNS). A change in the SNS during simulated microgravity could induce several physiological changes. It is associated with Su-Seung-Hwa-Gang in Korean medicine.

• 한국산학기술학회논문지
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• 제16권7호
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• pp.4450-4458
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• 2015

본 연구의 목적은 Yoga와 Pilates 운동 수행이 자율신경계에 미치는 영향을 분석하여 운동처방의 임상적 기초 자료를 제공하고자 하였다. 피험자는 체육전공 대학생 20명을 요가운동군(Yoga Group)과 필라테스운동군(Pilates Group)에 각각 10명씩 배정하였고, 자율신경계 측정은 운동 전, 운동 직후, 회복기 30분 후에 이루어졌다. 그 결과 첫째, 요가는 스트레스 지수와 평균맥박이 시기의 주효과와 시기와 집단의 상호작용효과의 유의한 차이를 보였다. 둘째, 요가는 교감활성과 자율신경균형이 시기의 주효과, 시기와 집단의 상호작용효과, 집단의 주효과 모두 유의한 차이를 보였다. 셋째, 맥박다양성, 부교감활성도, SDNN, RMSSD는 시기의 주효과는 유의한 차이를 보였고, 시기와 집단의 상호작용효과와 집단의 주효과는 통계적으로 유의한 차이를 나타내지 않았다. 따라서 요가는 스트레스 지수를 낮추고 평균맥박 감소의 효과를 얻을 수 있으며, 특히 요가 운동이 필라테스 운동보다 교감활성 감소와 자율신경균형에 더 긍정적인 영향을 미치는 것으로 사료된다.