• Journal of Acupuncture Research
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• 제26권4호
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• pp.99-106
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• 2009

Objectives : The antidepressant effect of the subchronic administration of the methanolic extract of wild ginseng(WG) was investigated compared with that of cultivated ginseng(CG, panax ginseng) extract. Methods : To assess the antidepressant effect of the ginseng extracts, tail suspension test(TST) was executed in mice after daily administration of WG or CG extract for five consecutive days. Results : The WG extract at daily dose of 600mg/kg significantly reduced the total duration of immobility in the TST, whereas there was no significant reduction at daily dose of 300mg/kg WG and 600mg/kg CG. There were no individual differences between experimental groups in open field test (OFT) to evaluate psychostimulant effects of WG or CG extract. In the high performance liquid chromatography(HPLC) analysis of the extracts, it was found that WG included four times more ginsenoside Rg1 and Re, three times more Rf, and six times more Rb1 and Rc than CG. Conclusions : It is suggested that WG extract has stronger antidepressant effect than CG extract, which means it includes more antidepressant compounds than CG.

• The Journal of Korean Physical Therapy
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• 제28권2호
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• pp.112-118
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• 2016

Purpose: This study examined thickness changes in abdominal muscles according to difficulty level of core stabilization exercise in healthy subjects. Methods: Thirty healthy subjects (age range: 21-30 years) volunteered under three conditions. In the first condition, the subjects performed an abdominal draw-in maneuver (ADIM). In the second condition, they performed the ADIM during quadruped exercise using a suspension device without extending their lower limbs. In the third condition, the subjects performed the ADIM during quadruped exercise using a suspension device while extending both lower limbs. The changes in thickness of transverse abdominis (TrA), internal oblique (IO), and external oblique (EO) muscles were measured by ultrasonography (US) imaging during the three experimental conditions, and US was used to measure the improvement ratio of muscle thickness at rest. The interventions were conducted over three trials in each condition, and measurements were performed on each subject by one examiner. Results: Our results showed a significantly greater increase in the muscle thickness of TrA and IO muscles after performance of quadruped exercise using a suspension device without knee extension (p<0.05) compared to the other conditions. The results also showed a significantly greater increase in the thickness changes of EO muscle in those who performed the ADIM during quadruped exercise using a suspension device with knee extension (p<0.05) compared with the ADIM only. Conclusion: These findings demonstrated positive evidence that a low-level core stabilization exercise could improve thickness of abdominal muscles.

• 대한토목학회논문집
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• 제36권1호
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• pp.21-29
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• 2016

본 연구에서는 고정하중을 받는 다경간 현수교의 예비해석을 위한 케이블 부재의 초기평형상태 해석방법을 제안한다. 본 연구에서 제안한 초기 평형상태 해석 알고리즘은 타 연구들에서 사용된 기존 방법들보다 간편하고 실용적이며, 3경간 현수교 및 다경간 현수교에 적용 가능하다. 제안방법의 타당성을 검증하기 위해, 3경간 현수교 예제모델과 4경간 현수교인 국내의 새천년대교 및 중국의 Yingwuzhou Bridge 모델을 사용하여 초기평형상태 해석을 수행하였다. 검증 결과, 본 연구에서 제안한 초기평형상태 해석방법에 의한 결과가 3경간 예제모델의 선행 연구결과 및 새천년대교의 설계값과 잘 일치하는 경향을 나타내었으며, 제안 방법은 Yingwuzhou Bridge에 대한 초기형상을 잘 유지하는 초기값들을 도출하였다.

• 동의신경정신과학회지
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• 제21권2호
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• pp.61-73
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• 2010

Objectives : The purpose of this study was to assess anti-depressive effects of Bee Venom(BV) on an Animal Model of Depression induced immobility stress. Methods : There was 2 pre-experiments MTT(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay and Western blot test and 3 main experiments ; forced swimming test, tail suspension test and Y-maze task. Male rats were used for main experiment. The subject was divided into 4 groups(1. control group injected only saline, without immobility stress 2. Negative group injected saline after 2 hours immobility stress 3. Positive group injected Amitriptyline after 2 hours immobility stress 4. BV group injected Bee Venom after 2 hours immobility stress). Each group consisted of 6 rats. Forced swimming test, tail suspension test, Y-maze task were used to evaluate anti-depressive effect of Bee Venom. Results : In MTT assay, as the density of BV increased, the existence rate of primary neuronal cell increased. In Western blot test, the density of CREB and AKT was increasing as time went by. In forced swimming test, BV group showed immobility decreased more than Normal group and Positive group. In tail suspension test, Normal group and Positive group showed immobility decreased more than BV group. In Y-maze task, BV group showed immobility decreased more than Normal group, but Positive group showed immobility decreased more than BV group. Conclusions : These results suggest that Bee Venom may have anti-depressive effect on depression.

• Structural Engineering and Mechanics
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• 제50권2호
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• pp.241-255
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• 2014

The girder of self-anchored suspension bridge is subjected to large compression force applied by main cables. So, serious damage of the girder due to breakage of hangers may cause collapse of the whole bridge. With the time increasing, the hangers may break suddenly for their resistance capacities decrease due to corrosion. Using nonlinear static and dynamic analysis methods and adopting 3D finite element model, the responses of a concrete self-anchored suspension bridge to sudden breakage of hangers are studied in this paper. The results show that the sudden breakage of a hanger has significant effects on tensions of the hangers next to the broken hanger, bending and torsion moments of the girder, moments of the towers and reaction forces of the bearings. The results obtained from dynamic analysis method are very different from those obtained from static analysis method. The maximum tension of hanger produced by breakage of a hanger exceeds 2.2 times of its initial value, the maximum dynamic amplification factor reaches 2.54, which is larger than the value of 2.0 recommended for cable-stayed bridge in PTI codes. If two adjacent hangers on the same side of bridge break one after another, the maximum tension of other hangers exceeds 3.0 times of its initial value. If the safety factor adopted to design hanger is too small, or the hangers have been exposed to corrosion, the bridge may collapse due to breakage of two adjacent hangers.

• EDISON SW 활용 경진대회 논문집
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• 제5회(2016년)
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• pp.246-255
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• 2016

When spring of the suspension is exerted by an external load, a car should be designed to prevent predictable damages and designed for a ride comfort. We used experiments design to design VON-MISES STRESS and K, a constant, of spring of suspension which is installed in a car as a goal level. We analyzed the result from Edison's Elastic - Plastic Analysis SW(CSD_EPLAST) by setting D, d, n as external diameter of coil, internal diameter of coil, the number of total coil respectively. The experiment design let the outcome be as Full-second order by using Box-Behnken which is one of response surface methods. Experimented and analyzed results based on the established experiments design, We found out design parameter which has desired VON-MISES STRESS and the constant K. Additionally, we predicted life time of when the external load was exerted by repeated load by using fatigue equation, and verification of plastic deformation has also been made. Additionally we interpreted a model, which is formed by optimized design parameter, with linear analysis and non-linear analysis, at the same time we also analyzed plastic deformation with the values from the both models. Finally, we predicted fatigue life of optimized model by using fatigue estimation theory and also evaluated a ride comfort with oscillation analysis.

• Journal of Menopausal Medicine
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• 제24권3호
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• pp.163-168
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• 2018

Objectives: To investigate the rate of postoperative urinary retention (POUR) and identify the risk factors for this complication in women who underwent transvaginal uterosacral suspension surgery. Methods: A retrospective chart review was conducted for 75 women who underwent transvaginal uterosacral suspension surgery with vaginal hysterectomy, repair of cystocele, and levator myorrhaphy with/without transobturator anti-incontinence surgery. POUR was defined as a need for continuous intermittent catheterization on the third day subsequent to removal of the urethral indwelling catheter. Results: Acute POUR was reported in 18 women (24.0%). Thirty-six of the 75 patients (48.0%) had undergone anti-incontinence surgery. Crude analysis revealed significant association between the following variables and the risk of POUR: hypertension, the lower average flow rate in the pressure-flow study (PFS), greater post-void residual (PVR) urine volume in PFS, and PVR >30% of the total bladder capacity (TBC) in PFS. In the logistic regression analysis, PVR >30% of the TBC in PFS was identified as the only significant predictor of POUR (odds ratio, 15.4; 95% confidence interval, 2.5-90.9; P = 0.003). Conclusions: The PVR >30% of the TBC in PFS was identified as the only predictive factor of acute POUR in women who underwent transvaginal uterosacral suspension surgery.

• 대한피부과학회지
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• 제56권9호
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• pp.552-555
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• 2018

Vitiligo is a commonly acquired cutaneous depigmentation disorder that affects 0.5~1% of the population worldwide. While phototherapy is the primary treatment for vitiligo, surgical methods can be used for treating patients who are refractory to conventional treatments. Herein, we present the case of a 14-year-old Korean girl who developed vitiligo after hematopoietic stem cell transplantation for the treatment of acute lymphoblastic leukemia. She had multiple depigmented patches on her lower legs that did not respond to narrow-band ultraviolet B phototherapy for 7 months. The depigmented patches were successfully treated by transplantation of non-cultured epidermal cell suspension from the epidermal roof of the suction blister in the right inner thigh. No adverse event, such as secondary infection or scarring in both the donor and recipient sites, was noted. We recommended that non-cultured epidermal cell suspension transplantation using the suction blister method would be a safe and effective option for the treatment of refractory vitiligo.

• 아시안잔디학회지
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• 제23권2호
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• pp.345-352
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• 2009

한국들잔디는 운동경기장이나 골프 코스 등에 폭넓게 쓰이는 난지형 잔디이다. 많은 품종은 영양체로 번식한다. 이 연구는 배아세포 유도와 식물체 재생을 위한 적정 배양액 개발과 배양조건을 연구하여, 한국잔디의 육종과 번식을 위한 세포배양 체계 확보를 목적으로 하였다. 그 결과 $Cu^{++}\;2.5mgL^{-1}$를 유도 배양액에 첨가하는 것이 캘러스 유도를 위한 최적 농도 조건 이였음을 보여주었다. Sub-culture의 횟수의 증가는 캘러스의 질을 향상시켰다. 세포 부유배양을 위한 최적 용량은 2.5에서 10mL 사이였으며 본 연구에서 58%의 식물체 재생산비율을 보였다.

• 대한통합의학회지
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• 제12권2호
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• pp.11-23
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• 2024

Purpose : The purpose of this study was to investigate the effect of exercise using a suspension device (sling and total body resistance exercise; TRX) on physical functional performance and postural balance. Methods : An experimental study comparing 2 different suspension exercise was conducted on 16 healthy college students. 16 subjects were assigned to two groups. They were classified into 8 sling group and 8 TRX group. Miniplus was used to evaluate physical functional performance. In this study, isokinetic resistance mode was used to compare and analyze seven movement patterns. Biorescue was used to evaluate postural balance. The intervention exercises in this study are as follows. Standing lean forward (SLF) using a sling and TRX was performed 3 times a week for 3 weeks. The SLF was held for 10 seconds and then rested for 15 seconds, repeated a total of 10 times for 3 sets. Results : In the TRX group, significant increases were observed in physical functional performance (p<.05). Among the differences between groups, significant differences were confirmed on the front of the right arm, the back of the left arm, and the back of the right arm. In the sling group, significant increases were observed in left, right, front, and overall dynamic balance (p<.05). A significant increase in posterior dynamic balance was confirmed in the TRX group (p<.05). There was no significant difference between groups. Conclusion : Based on the results of this study, TRX was effective in improving physical functional performance, while the sling was effective in enhancing postural balance. However, confirming the effectiveness of slings and TRX in the relationship between physical functional performance and postural balance proved inadequate. Therefore, additional research should be conducted to verify the effects of suspension.