• Title/Summary/Keyword: surface-modification technology

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Functionalization of Electrospun Nano/Micro-fibrous Scaffolds Using Gamma-ray Irradiation (감마선 조사법을 이용한 전기방사 나노/마이크로 섬유 지지체의 표면 기능화)

  • Lim, Jong-Young;Shin, Young Min;Choi, Jong-Bae;Jeong, Jin-Oh;Gwon, Hui-Jeong;Jeong, Sung In;Park, Jong-Seok;Lim, Youn-Mook
    • Journal of Radiation Industry
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    • v.7 no.1
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    • pp.45-49
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    • 2013
  • In tissue engineering application, a fibrous structure of scaffolds has been issued as an alternative system to regulate cell survival and tissue regeneration, and electrospinning technique has been popularly used to generate fibrous meshes or sheets mimicking the structure of native extracellular matrix (ECM). However, recent strategy in the scaffold development is expanded to provide the structural property as well as a biological property of native ECM, a variety of surface modification techniques have been used to introduce biological property. In this study, we developed biomimetic poly(L-lactide-co-${\varepsilon}$-caprolactone) (PLCL) nano- and micro-fibrous scaffolds as a unique platform with structural and biological properties with native ECM using electrospinning method and gamma-ray irradiation. Surface morphology of the scaffolds was observed by scanning electron microscopy, and alteration of surface property was evaluated with toluidine blue O staining, water contact angle measurement and ATR-FTIR analysis.

Surface Treatment of Mg95Zn4.3Y0.7 Alloy Powder Consolidates using Plasma Electrolytic Oxidation (플라즈마 전해산화공정을 이용한 Mg95Zn4.3Y0.7 합금분말 성형체의 표면특성제어)

  • Kim, J.H.;Choi, H.S.;Kim, D.H.;Hwang, D.Y.;Kim, H.S.;Kim, T.S.
    • Journal of Powder Materials
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    • v.15 no.2
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    • pp.95-100
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    • 2008
  • The investigation is to modify the mechanical and chemical properties of Mg alloys using a combination of rapid solidification and surface treatment. As the first approach, $Mg_{95}Zn_{4.3}Y_{0.7}$ was gas atomized and pressure sintered by spark plasma sintering process (SPS), showing much finer microstructure and higher strength than the alloys as cast. Further modification was performed by treating the surface of PM Mg specimen using Plasma electrolytic oxidation (PEO) process. During the PEO processing, MgO layer was initiated to form on the surface of Mg powder compacts, and the thickness and the density of MgO layer were varied with the reaction time. The thickening rate became low with the reaction time due to the limited diffusion rate of Mg ions. The surface morphology, corrosion behavior and wear resistance were also discussed.

Fabrication of Endothelial Cell-Specific Polyurethane Surfaces co-Immobilized with GRGDS and YIGSR Peptides

  • Choi, Won-Sup;Bae, Jin-Woo;Joung, Yoon-Ki;Park, Ki-Dong;Lee, Mi-Hee;Park, Jong-Chul;Kwon, Il-Keun
    • Macromolecular Research
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    • v.17 no.7
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    • pp.458-463
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    • 2009
  • Polyurethane (PU) is widely used as a cardiovascular biomaterial due to its good mechanical properties and hemocompatibility, but it is not adhesive to endothelial cells (ECs). Cell adhesive peptides, GRGDS and YIGSR, were found to promote adhesion and spreading of ECs and showed a synergistic effect when both of them were used. In this study, a surface modification was designed to fabricate an EC-active PU surface capable of promoting endothelialization using the peptides and poly(ethylene glycol) (PEG) spacer, The modified PU surfaces were characterized in vitro. The density of the grafted PEG on the PU surface was measured by acid-base back titration to the terminal-free isocyanate groups. The successful immobilization of pep tides was confirmed by amino acid analysis, following hydrolysis, and contact angle measurement. The uniform distribution of peptides on the surface was observed by scanning electron microscopy (SEM) and atomic force microscopy (AFM). To evaluate the EC adhesive property, cell viability test using human umbilical vein EC (HUVEC) was investigated in vitro and enhanced endothelialization was characterized by the introduction of cell adhesive peptides, GRGDS and YIGSR, and PEG spacer. Therefore, GRGDS and YIGSR co-immobilized PU surfaces can be applied to an EC-specific vascular graft with long-term patency by endothelialization.

Kelvin Ship Wake Modification due to Wind Waves

  • Lee, Kwi-Joo;Shugan, I.V.;An, Jung-Sun
    • Journal of Ocean Engineering and Technology
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    • v.22 no.5
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    • pp.1-6
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    • 2008
  • A kinematics model of a ship wake in the presence of surface waves generated by wind is presented. It was found that a stationary wave structure behind a ship covered a wedge region with the angle at the top of the wake and that only divergent waves were present in a ship wake instead of both the longitudinal and cross-waves, which are known as the Kelvin model. Ship motion at some angle to wind waves can cause an essential asymmetry of the wake, compressing its windward half.

A Study on the Surface Modification of the Super Alloy by Plasma Transferred Arc Overlay Welding Method

  • Kim, Young-Sik;Lim, Chang-Hoon;Hwang, Won-Seok;Choi, Young-Gook
    • Journal of Advanced Marine Engineering and Technology
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    • v.31 no.7
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    • pp.852-856
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    • 2007
  • The Plasma Transferred Arc(PTA) overlay welding method is lately introduced as one of the most useful surface overlay method of the engine component. In this paper, the overlay welding method on the Nimonic super alloy was established by the PTA overlay welding process using the same super alloy powder. The characteristics of the Co-base and Ni-base super alloy overlay layers were investigated through the metallurgical, abrasive and cavitation erosion test. The abrasive and cavitation characteristics were investigated at room and high temperature.

A Study on the Preparation of Antibacterial Biopolymer Film

  • Cho, Dong-Lyun;Na, Kun;Shin, Eun-Kyung;Kim, Hyun-JIn;Lee, Ki-Young;Go, Jin-Hwan;Choi, Choon-Soon
    • Journal of Microbiology and Biotechnology
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    • v.11 no.2
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    • pp.193-198
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    • 2001
  • Preparation of antibacterial biopolymer film which is suitable for food packaging film was investigated using K-carrageenan as a base material. K-Carrageenan showed good biodegradability and film-forming characteristic but poor mechanical properties under humid condition. Also, various bacteria grew well on its surface. The poor mechanical properties could be improved by mixing with alginate at a 1:1 ratio and crosslinking with $CaCl_2$ solution. Antibacterial property coul be provided by modifying the K-carrageenan film surface with acrylic acid plasma followed by ion-exchange with $Ag^+$ ions. Such prepared film still showed good biodegradability by various fongi.

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Comparative Analyses of Commercial Detonation Nanodiamonds

  • Puzyr, A.P.;Burova, A.E.;Bondar, V.S.;Rhee, C.K.;Rhee, W.H.;Hwang, K.C.
    • Journal of Powder Materials
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    • v.18 no.3
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    • pp.297-302
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    • 2011
  • Colloidal stability is one of crucial factors for many applications of nanodiamond. Despite recent development, nanodiamonds available on the market often exhibit a high impurity content, wide size distribution of aggregates and low resistance to sedimentation. In the current study, four commercial nanodiamond powders synthesized by detonation synthesis were surface modified and then separated with respect to the size into six fractions by centrifugation. The fractions were evaluated by zeta potential, particle size distribution and elemental composition. The results showed that the modified nanodiamonds form stable colloidal suspensions without sedimentation for a long time.

A Study on the Surface Modification of Polyimide Film by ion Implantation (이온주입법에 의한 폴리이미드 박막의 표면개질에 대한 연구)

  • Kim, J.T.;Yuk, J.H.;Park, J.K.;Hwang, M.H.;Lim, H.C.;Lee, D.C.
    • Proceedings of the KIEE Conference
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    • 1997.07d
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    • pp.1546-1548
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    • 1997
  • We investigated microhardness, friction, wear and wettability of polyimide for finding out the influence of ion implantation on surface properties. For increasing doses microhardness increased. A reduction of the friction coefficient was most cases correlated with a reduction of wear. The contact angles of water for $B^+$, $N^+$ implanted polyimide decreased from $76^{\circ}$ to zero, as the fluences increased energy of 50, 200 keV.

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Duplex Surface Modification with Micro-arc Discharge Oxidation and Magnetron Sputtering for Aluminum Alloys

  • Tong, Honghui;Jin, Fanya;He, Heng
    • Journal of the Korean Vacuum Society
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    • v.12 no.S1
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    • pp.21-27
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    • 2003
  • Micro-arc discharge oxidation (MDO) is a cost-effective plasma electrolytic process which can be used to improve the wear and corrosion resistance of Al-alloy parts by forming a alumina coating on the component surface. However, the MDO coated Al-alloy components often exhibit relatively high friction coefficients and low wear resistance fitted with many counterface materials, additionally, the pitting corrosion for the MDO coated AI-alloy components, especially for a thinner alumina coating, often occurs in atmosphere circumstance due to the porous alumina coats. Therefore, a duplex treatment, combining a MDO coated ahumina thin layer with a TiN coating, prepared by magnetron sputtering (MS), has been investigated. The Vicker's microhardness, pin-on-disc, electrochemical measurement, salt spray, XRD and SEM tests were used to characterize and analyze the treated samples. The work demonstrates that the MDO/MS coated samples have a combination of a very low friction coefficient and good wear resistance as well as corrosion since the micro-holes on alumina coating are partly or fully covered by TiN material.

Fundamental study on cancer therapy by blocking newborn blood vessels by magnetic force control

  • KIRIMURA, Makoto;AKIYAMA, Yoko;NISHIJIMA, Shigehiro
    • Progress in Superconductivity and Cryogenics
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    • v.20 no.2
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    • pp.11-15
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    • 2018
  • In this study, a cancer treatment by accumulating and aggregating ferromagnetic particles in newborn blood vessels was examined. It is necessary for this treatment to control dispersion-aggregation property of ferromagnetic particles. Ferromagnetic particles required in this method disperse at low magnetic field, aggregate at high magnetic field and maintain the aggregation even after removal of the magnetic field. In order to control the dispersion-aggregation property, the surface of magnetite particles was modified with higher fatty acids having different lengths. As a result, we succeeded to prepare propionic acid-modified magnetite particles that form irreversible aggregation by magnetic field. The model experiments simulating newborn blood vessels showed that these particles can block the flow by the magnetic field, and the blockage was maintained after removal of the magnetic field.