• Title/Summary/Keyword: support variety

Search Result 1,002, Processing Time 0.029 seconds

Synthesis of Heterocyclic Substituted Pyridine Analogs as Potential Therapeutics for Neurodegenerative Diseases

  • Park, Haeil;Peter A. Crooks
    • Proceedings of the Korean Society of Applied Pharmacology
    • /
    • 1999.04a
    • /
    • pp.1-4
    • /
    • 1999
  • The potential therapeutic benefit of nicotinic ligands in a variety of neurodegenerative pathologies involving the CNS has energized research efforts to develop nicotinic acetylcholine receptor (nAChR) subtype-selective ligands. In particular, there has been a concerted effort to develop nicotinic compounds with selectivity for CNS nAChRs as potential pharmacological tools in the management of these disorders. The characterization of other novel nicotinic ligands such as epibatidine. showing a marked increase in potency at nAChRs, has provided additional support for the development of potent, selective ligands at individual nAChR subtypes. We have developed and studied a number of nicotinic compounds to identify potential candidates exhibiting such selectivity. In the present study, we report the synthesis and biological evaluations of some azabicyclic and azatricyclic nicotine analogs to decipher the relationship among steric requirements of the nicotine's pyrrolidine ring system, binding affinity and subtype-selectivity.

  • PDF

The Study on the Dynamic Bandwidth Allocation Algorithm using by Cell Delay Variation (셀지연변이를 이용한 동적 대역폭 할당 알고리즘에 관한 연구)

  • 신승호;박상민
    • Proceedings of the Safety Management and Science Conference
    • /
    • 2000.11a
    • /
    • pp.131-134
    • /
    • 2000
  • Broadband networks are designed to support a wide variety of services with different traffic characteristics and demands for Quality of Services. Bandwidth allocation methods can be classified into two major categories: static and dynamic. In static allocation, bandwidth is allocated only at call setup time and the allocated bandwidth is maintained during a session. In dynamic allocation, the allocated bandwidth is negotiated during a session. The purpose of this paper is to develop policies for deciding and for adjusting the amount of bandwidth requested for a best effort connection over such as ATM networks. This method is to develop such policies that a good trade off between utilization and latency using cell delay variation to the forecast the incoming traffic in the next period. The performances of the different polices are compared by simulations.

  • PDF

A Keyword Query Processing Technique of OWL Data using Semantic Relationships (의미적 관계를 이용한 OWL 데이터의 키워드 질의 처리 기법)

  • Kim, Youn Hee;Kim, Sung Wan
    • Journal of Korea Society of Digital Industry and Information Management
    • /
    • v.9 no.1
    • /
    • pp.59-72
    • /
    • 2013
  • In this paper, we propose a keyword query processing technique based on semantic relationships for OWL data. The proposed keyword query processing technique can improve user's search satisfaction by performing two types of associative search. The first associative search uses information inferred by the relationships between classes or properties during keyword query processing. And it supports to search all information resources that are either directly or indirectly related with query keywords by semantic relationships between information resources. The second associative search returns not only information resources related with query keywords but also values of properties of them. We design a storage schema and index structures to support the proposed technique. And we propose evaluation functions to rank retrieved information resources according to three criteria. Finally, we evaluate the validity and accuracy of the proposed technique through experiments. The proposed technique can be utilized in a variety of fields, such as paper retrieval and multimedia retrieval.

The Application of MultiLayered Primitive-Composite Model for Integrated Design System of Agricultural Facilities (농업시설물의 통합설계시스템 개발을 위한 객체 모델링에 관한 연구(구조 및 재료 \circled1))

  • 배연정;이정재;윤성수;김한중
    • Proceedings of the Korean Society of Agricultural Engineers Conference
    • /
    • 2000.10a
    • /
    • pp.226-232
    • /
    • 2000
  • The design of agricultural facilities is the consistent activities, which systematically analyze all the actual conditions, design the unit structures, and improve the faming environment through efficient organization of the unit facility. The design of agricultural facilities is composed of site study, preliminary design, primary design, and detail design. Integrated design system can manage and process the information created by and used in all steps of design process. Formal data models of these design activities are important conceptual steps in development of integrated design system. However, most of existing models are not available for agricultural facilities. To support efficiently developing the integrated design system of agricultural facilities, we have developed the Multi-Layered Primitive-Composite mode I through object-oriented analysis of agricultural facilities. The MPC model not only satisfies the characteristics of agricultural facility, such as variety, coupling, informal data, but also improves abilities of integrated design system such as extensibility, flexibility, and granularity. The paper presents a formal definition of the MPC model.

  • PDF

Technical Trend and Challenging Issues for Cellular-Based Industrial IoT (이동통신기반 Industrial IoT 기술 동향)

  • Kim, W.I.;Kim, E.A.;Ko, Y.J.;Song, J.S.;Yoon, C.H.;Moon, S.H.;Kim, C.S.;Baek, S.K.
    • Electronics and Telecommunications Trends
    • /
    • v.33 no.5
    • /
    • pp.51-63
    • /
    • 2018
  • Mobile cellular technology is evolving to accommodate a variety of vertical services, expanding the application from human-to-human communication to the Internet of Things(IoT). In particular, the fourth industrial revolution, bringing in a new vision in future smart factory, necessitates a new paradigm shift in wireless communication. Low latency and high reliability is a key issue in wireless applications for industrial IoT such as factory automation. In this paper, we review the recent progress in 5G URLLC (Ultra-Reliable Low Latency Communication) and discuss use cases, requirements, challenging technical issues, and potential solutions to support wireless factory automation such as discrete automation and process automation.

Parents of Children with Asperger Syndrome: Relationships between Early Attachment Experiences and Parenting Behaviors

  • Angus, Jeanne
    • Child Studies in Asia-Pacific Contexts
    • /
    • v.3 no.1
    • /
    • pp.1-12
    • /
    • 2013
  • Research with parents of children with Asperger Syndrome was conducted to assess whether the level of positive parental attachment correlated positively with positive parenting behaviors and negatively with negative parenting behaviors. Participants were recruited from internet. The Parental Bonding Inventory measured parents' perception of their bonding or attachment with three aspects of their own parents: warmth, control, and care. In the Parenting Behavior Inventory, parents reported recent interaction/reaction behaviors with their child, and results focused on two aspects of parenting, supportive/engaged and hostile/coercive behaviors: each identified as problematic to parenting and attributable to a variety of specific parenting behaviors. Analysis of demographic variables for correlations with positive parenting behaviors and negative parenting behaviors were carried out by Pearson correlations. Two separate standard multiple regressions, one for positive parenting behaviors and one for negative parenting behaviors, were conducted. Findings support the hypothesis that positive early attachment experience of parents has a significant impact upon their own positive parenting skills with their child with Asperger Syndrome. However, multiple regression of negative parenting behavior found no significant negative contribution by parental attachment. Demographic variables proved to be important.

HUMAN-MACHINE INTERACTION IN NUCLEAR POWER PLANTS

  • YOSHIKAWA HIDEKAZU
    • Nuclear Engineering and Technology
    • /
    • v.37 no.2
    • /
    • pp.151-158
    • /
    • 2005
  • Advanced nuclear power plants are generally large complex systems automated by computers. Whenever a rare plant emergency occurs the plant operators must cope with the emergency under severe mental stress without committing any fatal errors. Furthermore, The operators must train to improve and maintain their ability to cope with every conceivable situation, though it is almost impossible to be fully prepared for an infinite variety of situations. In view of the limited capability of operators in emergency situations, there has been a new approach to preventing the human error caused by improper human-machine interaction. The new approach has been triggered by the introduction of advanced information systems that help operators recognize and counteract plant emergencies. In this paper, the adverse effect of automation in human-machine systems is explained. The discussion then focuses on how to configure a joint human-machine system for ideal human-machine interaction. Finally, there is a new proposal on how to organize technologies that recognize the different states of such a joint human-machine system.

A Study on Digital Signal Content System for Facility Management (시설 관리용 디지털 신호 컨텐츠 시스템 연구)

  • Park, Kyeongmo;Ahn, Byeong-Tae
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
    • /
    • 2015.10a
    • /
    • pp.1030-1032
    • /
    • 2015
  • In this paper, we developed a system that output and service using vairous contents with the inspection and management industry facilities in the operating system based on wireless network. This system can output to the display device at the same time, work management and a variety of content to the inspection facilities. And it outputs received contents of the advertising service provider in real-time. Therefore, this system support real-time facility management and various contents in the building at the same time.

  • PDF

Optical Super-highway Network Maintenance and System Trends (초고속통신망 광케이블의 유지보수 및 시스템 발전방향)

  • Choi, Shin-Ho;Lee, Byeong-Wook;Park, Kap-Seok;Jang, Eun-Sang;Kim, Seong-Il
    • Proceedings of the KIEE Conference
    • /
    • 1998.07g
    • /
    • pp.2495-2497
    • /
    • 1998
  • Fiber optic facilities are increasingly being deployed in loop applications for both busines and residential areas. These facilities support a variety of communications services that include high speed data and video using leading technologies such as Synchronous Optical Network (SONET), Wavelength Division Multiplexing(WDM). This proliferation of fiber optic facilities combined with the increasing pressure on network operators to reduce costs are fostering increased automation to reduce labor costs associated with providing and maintaining communications services. Effective fiber management and accurate records can improve the reliability and integrity of the future telecommunications networks and the quality of customer services. This paper describes the trend forward and the need for the deployment of Fiber Administration System (FAS) into the operations enviroment of a typical network provider.

  • PDF

Test and Field Application Analysis for Root Barrier using Aluminum Film Adhered to PVC and Waterproofing using E.P Sheet with Asphalt Membrane for Green Roof System (PVC 및 알루미늄을 진공 접착한 방근시트와 E.P시트 및 도막방수층을 부분 절연한 방수/방근 복합공법의 옥상녹화 적용성 평가에 관한 실험적 연구)

  • Oh, Sang-Keun;Kwon, Si-Won;Park, Jin-Sang;Park, Sang-Chan
    • Proceedings of the Korean Institute of Building Construction Conference
    • /
    • 2006.11a
    • /
    • pp.71-74
    • /
    • 2006
  • The introduction of materials and methods of construction which are appropriated to property of green roofs could be a decisive factor in a long-range durability and economical maintenance cost, moreover, it support to variety construction system and organization. In this paper I focused to assure the basic system for waterproofing materials and root barrier apply to green roof as searching the application of field condition. And I suggest proper waterproofing and root barrier as considering the mutual connection and plant growth. and it can be a standard model to adopt to domestic green roof system.

  • PDF