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Studies on NO, nNOS, eNOS, iNOS and NE Expression by Acupuncture at SP4, KI4 and LR5 (족삼음경의 락혈에 시술된 침 자극에 의한 NO, NOS, NE 발현 연구)

  • Lee, Yumi;Shin, Wook;Choi, Donghee;Kim, Mirae;Na, Changsu;Youn, Daehwan
    • Korean Journal of Acupuncture
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    • v.34 no.1
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    • pp.37-46
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    • 2017
  • Objectives : The acupuncture about acupoint affects the production of NO, NOS, and NE.Local action of acupuncture is important for acupuncture treatment. To prove this, the revelation degree of NO, NOS, and NE was observed by stimulating the acupuncture at the connecting point of SP4, KI4, and LR5 in the depths of Superficial layer, Middle layer and Deep layer. Methods : Needles were inserted into rats, on each right and left sides of the connecting point, SP4, KI4 and LR5 acupoints which are the stream points of the foot meridian. After insertion, needles were retained for three minutes. After the retention, rat was sacrificed via cardiac puncture, and tissues of each SP4, KI4 and LR5 point near meridian vessel was extracted to examine the changes in the expression of NO, NOS and NE. Results : In terms of the effect in NO production, there was significant increase in the Superficial layer, Middle layer and Deep layer at KI4. In terms of the effect in NE production, there was significant decrease in the Superficial layer at SP4 and increase in the Superficial layer, Middle layer and Deep layer at LR5. In terms of the effect in nNOS production, there was significant increase in the Superficial layer, Middle layer and Deep layer at SP4 also in the Superficial layer at KI4. In terms of the effect in eNOS production, there was a significant increase in the Superficial layer, Middle layer and Deep layer at SP4, KI4 and LR5. In terms of the effect in iNOS production, there was significant increase in the Superficial layer, Middle layer and Deep layer at SP4, KI4 and LR5. Conclusions : The effect of acupuncture applied at the connecting point of six meridians of the foot on the activities of NO, NOS and NE could be observed, and it can be induced from the effect of needle stimulation on disrupted local and systemic nervous responses.

Changes of Pre-Auricular Cutaneous Blood Flow and Skin Temperature after Dry Heat Therapy and Moist Heat Therapy (건열요법과 습열요법 적용후 전이부 표층부 혈류량과 피부온도의 변화)

  • Hong, Yong-Jae;Kim, Cheul;Park, Moon-Soo;Kim, Young-Jun
    • Journal of Oral Medicine and Pain
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    • v.31 no.1
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    • pp.47-57
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    • 2006
  • The purpose of this study was to assess the effects of the superficial heat therapy on the cutaneous blood flow and the skin temperature at pre-auricular region. Two types of the superficial heat therapy-moist hot pack & infrared lamp- were applied to 20 healthy subjects(male: 10, female: 10). For each subject, the two parameters of cutaneous blood flow and skin temperature were measured before and after heat therapy, using laser doppler flowmetry(LDF). The author analyzed the differences of the effects between the two therapies and also characteristics of responsiveness between the two parameters. The results were as follows : 1. The two parameters were significantly increased after both superficial heat therapies. 2. Skin temperature showed a maximum peak immediately after both superficial heat therapies, but cutaneous blood flow showed a maximum peak 4 minutes after both superficial heat therapies. 3. Increased cutaneous blood flow after application of moist hot pack lasted longer than infrared lamp. 4. Increased skin temperature after both superficial heat therapies lasted for 60 minutes, but increased skin temperature after infrared lamp decreased more rapidly than moist hot pack. 5. Amount of changes in cutaneous blood flow after infrared lamp was larger in female than in male, but no significant gender difference was found since 20 minutes after infrared lamp. Both moist hot pack and infrared lamp showed favorable effectiveness in raising cutaneous blood flow and skin temperature. Moist hot pack was slightly superior in maintaining this effect.

Measurement of Bubble Size in Flotation Column using Image Analysis System (이미지 분석시스템을 이용한 부선컬럼에서 기포크기의 측정)

  • An, Ki-Seon;Jeon, Ho-Seok;Park, Chul-Hyun
    • Resources Recycling
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    • v.29 no.6
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    • pp.104-113
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    • 2020
  • Bubble size in froth flotation has long been recognized as a key factor which affects the bubble residence time, the bubble surface area flux (Sb) and the carrying rate (Cr). This paper presents method of bubble size measurement, relationship between operating variables and gas dispersion properties in flotation column. Using high speed camera and image analysis system, bubble size has been directly measured as a function of operating parameters (e.g., superficial gas rate (Jg), superficial wash water rate (Jw), frother concentration) in flotation column. Relationship compared to measured and estimated bubble size was obtained within error ranges of ±15~20% and mean bubble size was 0.718mm. From this system the empirical relationship to control the bubble size and distribution has been developed under operating conditions such as Jg of 0.65~1.3cm/s, Jw of 0.13~0.52cm/s and frother concentration of 60~200ppm. Surface tension and bubble size decreased as frother concentration increased. It seemed that critical coalescence concentration (CCC) of bubbles was 200ppm so that surface tension was the lowest (49.24mN/m) at frother concentration of 200ppm. Bubble size tend to increase when superficial gas rate (Jg) decreases and superficial wash water rate Jw and frother concentration increase. Gas holdup is proportional to superficial gas rate as well as frother concentration and superficial wash water rate (at the fixed superficial gas rate).

Counter-Current Air-Water Flow in Narrow Rectangular Channels With Offset Strip Fins

  • Kim, Byong-Joo;Sohn, Byung-Hu;Koo, Kee-Kahb
    • Journal of Mechanical Science and Technology
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    • v.17 no.3
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    • pp.429-439
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    • 2003
  • Counter-current two-phase flows of air- water in narrow rectangular channels with offset strip fins have been experimentally investigated in a 760 mm long and 100 mm wide test section with 3.0 and 5.0 mm gap widths. The two-phase flow regime, channel-average void fractions and two-phase pressure gradients were studied. Flow regime transition occurred at lower superficial velocities of air than in the channels without fins. In the bubbly and slug flow regimes, elongated bubbles rose along the subchannel formed by fins without lateral movement. The critical void fraction for the bubbly-to-slug transition was about 0.14 for the 3 mm gap channel and 0.2 for the 5 mm gap channel. respectively. Channel-average void fractions in the channels with fins were almost the same as those in the channels without fins. Void fractions increased as the gap width increased, especially at high superficial velocity of air. The presence of fins enhanced the two-phase distribution parameter significantly in the slug flow, where the effect of gap width was almost negligible. Superficial velocity of air dominated the two-phase pressure gradients. Liquid superficial velocity and channel gap width has only a minor effect on the pressure gradients.

Clinical Application of the Adenosine Triphosphate-based Response Assay in Intravesical Chemotherapy for Superficial Bladder Cancer

  • Ge, Wen-Qing;Pu, Jin-Xian;Zheng, Shi-Ying
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.2
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    • pp.689-692
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    • 2012
  • Objective: To investigate correlations between adenosine triphosphate chemotherapy response assay (ATP-CRA) and clinical outcomes after ATP-CRA-based chemotherapy for drug selection in patients receiving intravesical chemotherapy to prevent recurrence of superficial bladder cancer after surgery. Methods: The chemosensitivities of 12 anticancer drugs were evaluated, including 5-Fu ADM, and EPI, using ATP-CRA and primary tumor cell culture in 54 patients. In addition, a further 58 patients were treated according to clinical experience. Differences in post-chemotherapeutical effects between drug sensitivity assay and experience groups were compared. Results: The evaluable rate of the test was 96.3%, the clinical effective rate was 80.8%, the sensitivity rate was 97.6% (41/42), the specificity was 20%, the total predicting accuracy was 74.3%, the positive predictive value was 83.7% (41/49), the negative predictive value was 66.7% (2/3); in the drug sensitivity test group, the clinical effective rate was 80.8%, the experience group response rate was 63.8%, with a significant difference in clinical effects between the ATP-based sensitivity and experience groups (${\chi}^2$=7.0153, P<0.01). Conclusion: ATP-CRA is a stable, accurate and potentially practical chemosensitivity test providing a predictor of chemotherapeutic response in patients with superficial bladder cancer.

Anatomical variations of the innervated radial artery superficial palmar branch flap: A series of 28 clinical cases

  • Yang, Jae-Won
    • Archives of Plastic Surgery
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    • v.47 no.5
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    • pp.435-443
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    • 2020
  • Background The innervated radial artery superficial palmar branch (iRASP) flap was designed to provide consistent innervation by the palmar cutaneous branch of the median nerve (PCMN) to a glabrous skin flap. The iRASP flap is used to achieve coverage of diverse volar defects of digits. However, unexpected anatomical variations can affect flap survival and outcomes. Methods Cases in which patients received iRASP flaps since April 1, 2014 were retrospectively investigated by reviewing the operation notes and intraoperative photographs. The injury type, flap dimensions, arterial and neural anatomy, secondary procedures, and complications were evaluated. Results Twenty-eight cases were reviewed, and no flap failures were observed. The observed anatomical variations were the absence of a direct skin perforator, large-diameter radial artery superficial palmar branch (RASP), and the PCMN not being a single branch. Debulking procedures were performed in 16 cases (57.1%) due to flap bulkiness. Conclusions In some cases, an excessively large RASP artery was observed, even when there was no direct skin perforator from the RASP or variation in the PCMN. These findings should facilitate application of the iRASP flap, as well as any surgical procedures that involve potential damage to the PCMN in the inter-thenar crease region. Additional clinical cases will provide further clarification regarding potential anatomical variations.

Reverse Superficial Sural Artery Flap for Reconstruction of Soft Tissue Defect (역혈행성 비복 동맥 피판술을 이용한 연부 조직 결손의 재건)

  • Lee, Sang-Soo;Lee, Young-Ho;Kim, Joo-Sung;Choi, Jae-Hyuck;Lee, Young-Hyun;You, Yeon-Sik;Nam, Il-Hyun
    • Journal of Korean Foot and Ankle Society
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    • v.6 no.1
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    • pp.46-53
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    • 2002
  • Purpose: We would introduce the reverse superficial sural artery flap to reconstruct soft tissue defect on lower leg, ankle, and hind-foot. Materials and Method: From October 1998 to December 2001, we reconstructed 12cases (l2patients) of soft tissue defect around the hind - foot, ankle, and distal lower extremity with the reverse sural artery flap. Results: The time for flap dissection was 28 minutes in average. The size of the flap was from $4\times3cm$ to $14\times10cm$. All flaps survived. Conclusion: The reverse superficial sural artery flap is the useful technique for the soft tissue defect in the lower leg and the foot.

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Effect of Heat Therapy to Superficial and Deep Body Temperatures according to Applying Dry and Moist Heats on Shoulder and Thigh (어깨와 대퇴부위에 건열과 습열 적용이 피부온도와 심부체온에 미치는 영향)

  • Lim, Nan-Young;Jeong, Hyeon-Cheol;Lee, Seung-Won;Kim, Woo-Jin
    • Journal of Korean Biological Nursing Science
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    • v.13 no.3
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    • pp.269-275
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    • 2011
  • Purpose: This study was designed to help preparing the evidence-based data for the manual of heat applications by finding the differences of superficial and core temperatures after applying dry and moist heats on shoulder and thigh. Methods: Moist and dry heats were alternately applied on the 33 subjects a day apart from May 15, 2010 through June 9, 2010. The experiment was conducted with $23^{\circ}C$ to $25^{\circ}C$ room temperature and 50% to 66% of moisture from 2 to 6 p.m. After heat was applied on the shoulder of the subjects wearing shorts and gowns for 30 minutes, their superficial and core temperatures were measured. The same method was used on the thigh after two hours. Results: Both superficial and core temperatures on the shoulder and thigh increased significantly after heat therapy. There was no significant difference between the temperatures before and after intervention according to applying methods and regions. Conclusion: This study provides a theoretical basis that a dry heat is a convenient nursing intervention for hypothermic patients.

The Treatment of Concentrated Organic Alcoholic Distillery Wastewater by the Fluidized-Bed Biofilm Reactor (생물막 유동층 반응기에 의한 주정공장의 고농도 유기성 폐수처리)

  • 김동석;장희재
    • KSBB Journal
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    • v.6 no.4
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    • pp.345-350
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    • 1991
  • The purpose of this study is to investigate biomass characteristics and organic removal efficiency by changing superficial upflow velocity and organic loading rate in treating alcoholic distillery wastewater. Since the biomass concentration and the thickness of biofilm are very sensitive to superficial upflow velocity, a high concentration of biomass could be achieved by decreasing superficial upflow velocity that lowered the organic removal efficiency. Therefore, superficial upflow velocity should be controlled as to give optimum conditions and removal efficiency. Generally, activated sludge system shows 70% COD removal efficiency at$1.5kgCOD/m^3{\cdot}day$, but the fluidized-bed biofllm reactor shows 80% COD removal efficiency even at 6kgCOD/$m^2{\cdot}day$.

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Pseudoaneurysm of the superficial temporal artery after blunt trauma: case report and literature review

  • Kang, Inho;Mo, Young Woong;Jung, Gyu Yong;Shin, Hea Kyeong
    • Archives of Craniofacial Surgery
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    • v.23 no.3
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    • pp.130-133
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    • 2022
  • An 88-year-old man presented with a left temporal pulsatile mass that developed after blunt trauma. Based on suspicion of hematoma, needle aspiration was performed with the removal of approximately 15 mL of blood. No evident improvement was noted, and active arterial bleeding was observed at the needle puncture site. Doppler ultrasonography revealed a "yin-yang" sign, and the mass was diagnosed as a pseudoaneurysm of the left superficial temporal artery. Under general anesthesia, the superficial temporal artery was ligated and the pseudoaneurysm was removed. Superficial temporal artery pseudoaneurysm is a rare facial tumor that generally occurs after blunt trauma. Due to its rarity, pseudoaneurysms are often misdiagnosed as hematoma. The treatment of choice is excision, although endovascular intervention is a potential treatment option. However, when a pseudoaneurysm is small, conservative treatment can be used.