• 공업화학
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• 제32권5호
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• pp.556-561
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• 2021

최근 산화철 나노입자는 외부의 자기장에 반응하는 자성의 특성과 생체적합성이 뛰어나 약물전달시스템(drug delivery system, DDS)에 관한 많은 연구의 소재로 사용되어져 왔다. 본 연구에서는 마이크로니들(microneedles, MNs)의 매트릭스 물질로 HA (hyaluronic acid)와 CMC (carboxy methyl cellulose)를 이용하여 SIONs (superparamagnetic iron oxide nanoparticles)이 함유된 HA-SMNs (hyaluronic acid-superparamagnetic microneedles)와 CMC-SMNs (carboxy methyl cellulose-superparamagnetic microneedles)를 제조하였으며, SEM (scanning electron microscopic), SQUD-VSM (superconducting quantum interference device-vibrating sample magnetometer), FMMD (frequency mixing magnetic detection), 고분자 및 바이오 멤브레인을 이용하여 SMNs의 다양한 특성을 조사하였다. SQUID-VSM 측정 결과 SIONs이 포함된 HA-SMNs와 CMC-SMNs에서 초상자성의 특성이 나타났으며, FMMD 측정에서는 SIONs 농도가 증가함에 따라 신호 강도에 변화가 확인되었다. 또한 SMNs의 바이오 막을 통한 HA-SMNs와 CMC-SMNs의 투과도 분석에서는 각각 평균 92.5%와 98.5%의 피부 투과율이 조사되었다. 이러한 결과를 통해 SMNs 제형은 경피약물전달시스템(transdermal drug delivery system, TDDS) 및 MR(magnetic mesonance) molecular imaging 분야의 전달소재로 활용될 수 있을 것으로 기대한다.

• Progress in Superconductivity
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• 제8권2호
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• pp.158-163
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• 2007

YBCO do superconducting quantum interference device (SQUID) magnetometers based on bicrystal junctions have been fabricated for magnetocardiograph (MCG) measurements. We could fabricate YBCO SQUID magnetometers having magnetic field noise of about $20fT/Hz^{1/2}$ at white noise region. We have developed an MCG system employing the high performance SQUID magnetometers. The lightweight MCG system, requiring liquid nitrogen as a coolant, consists of 6-channel SQUID sensors, an adjustable patient bed with sliding motion, and data analyses software. The MCG system could record quite clear MCG signals in a room with moderate magnetic shielding. In normal operation with multi-position MCG measurements, we could obtain clear 48-point mappings of magnetic field map and current source map with high enough signal qualities far clinical trials.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2002년도 추계학술대회 논문집 Vol.15
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• pp.268-271
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• 2002

The goal of the research is to study and describe a new stressed state of High Temperature Superconducting (High-Tc) YBCO Films, to create of SQUIDs (Superconducting Quantum Interference Device) on the bases of these Films with maximal sensitivity. The experimental investigation of the stressed films grown by laser ablation method and its properties, the fabrication of the dc-SQUIDs with maximal sensitivity on the bases of the stressed YBCO films were carried out. The stressed film having the value of the critical current density $J_{c}=3{\cdot}10^{5}A/cm^{2}$ was the more stable than others.

• 한국초전도ㆍ저온공학회논문지
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• 제5권1호
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• pp.21-26
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• 2003

We designed and constructed a multichannel superconducting quantum interference device (SQUID) magnetometer system to measure magnetic fields from the human brain. We used a new type of SQUID, the double relaxation oscillation SQUID (DROS). With high flux-to-voltage transfers of the DROS, about 10 times larger than the dc SQUIDs, simple flux-locked loop circuits could be used for SQUID operation. Also the large modulation voltage of the DROS, typically being 100 $mutextrm{V}$, enabled stable flux-locked loop operation against the thermal offset voltage drift of the preamplifier. The magnetometers were fabricated using the Nb/AlOx/Nb junction technology. The SQUID system consists of 37 signal magnetometers, distributed on a semispherical surface, and 11 reference channels were installed to pickup background noises. External feedback was used to eliminate the magnetic coupling with the adjacent channels. The liquid helium dewar has a capacity of 29 L and boil-off rate of about 4 L/d with the total 48 channel insert. The magnetometer system has an average noise level of 3 fT/√Hz at 100 Hz, inside a shielded loon, and was applied to measure auditory-evoked fields.

• 한국초전도학회:학술대회논문집
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• 한국초전도학회 1999년도 High Temperature Superconductivity Vol.IX
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• pp.27-32
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• 1999

We developed a 40-channel superconducting quantum interference device (SQUID) system for neuromagnetic measurements. The main features of the system are use of double relaxation oscillation SQUID (DROS), and planar gradiometer for measuring tangential field components. The DROSS with high flux-to-voltage transfers enabled direct readout of the SQUID output by room-temperature electronics and simple flux-locked loop circuits could be used for SQUID operation. The pickup coil is an integrated first-order planar gradiometer with a baseline of 40 mm. The average noise of the 40 channels is around 1.2 fT/cm/${\sqrt{Hz}}$ at 100 Hz, corresponding to the field noise of 5 fT/${\sqrt{Hz}}$ at 100 Hz, operated inside a magnetically shielded room. The 40-Channel system was applied to measure auditory-evoked neuromagnetic fields.

• Progress in Superconductivity
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• 제2권1호
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• pp.20-26
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• 2000

A 40-channel superconducting quantum interference device (SQUID) system was constructed for measuring neuromagnetic fields. Main features of the system are the use of double relaxation oscillation SQUIDs (DROSs), and planar gradiometers measuring magnetic field components tangential to the head surface. The DROSs with high flux-to-voltage transfers enabled direct readout of the SQUID output by room-temperature dc preamplifiers and simple flux-locked loop circuits could be used for SQUID operation. The pickup coil is an integrated first-order planar gradiometer with a baseline of 40 mm. Average noise level of the 40 channels is around 1.2 $fT/cm/{\surd}Hz$ at 100 Hz, corresponding to a field noise of 5 $fT/{\surd}Hz$, operated inside a magnetically shielded room. The SQUID insert was designed to have low thermal load, minimizing the loss of liquid helium. The constructed system was applied to measure auditory-evoked neuromagnetic fields.

• 한국초전도학회:학술대회논문집
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• 한국초전도학회 2003년도 High Temperature Superconductivity Vol.XIII
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• pp.59-59
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• 2003

• 한국초전도학회:학술대회논문집
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• 한국초전도학회 2002년도 High Temperature Superconductivity Vol.XII
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• pp.43-43
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• 2002

• 한국초전도학회:학술대회논문집
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• 한국초전도학회 2002년도 High Temperature Superconductivity Vol.XII
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• pp.45-45
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• 2002

• 한국컴퓨터정보학회:학술대회논문집
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• 한국컴퓨터정보학회 2018년도 제58차 하계학술대회논문집 26권2호
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• pp.179-180
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• 2018

자계 검출 센서는 여러 가지 종류가 있으나 벽면에 흐르는 미소 자계 및 차폐 전선에서 검출이 가능한 구조는 초전도 양자 간섭 소자(SQUID)가 주로 사용되지만 가격 및 물성 재료 특성으로 인하여 특수 용도로 사용되고 있다. 이에 본 연구에서는 전선으로부터 발생되는 저주파 자장을 검출할 수 있고 휴대성 및 가격이 저렴한 구조인 코일형 자계측정기를 개발하기 위해 자기 코어 및 코일 Turn수 변화에 따른 자계 검출 감도를 조사하여 최적의 구조를 설정하였다.