• Journal of Microbiology and Biotechnology
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• v.30 no.6
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• pp.893-902
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• 2020

Propolis is a resinous substance that is collected by Apis mellifera from plant sources and is used in traditional medicine. To study the phytochemical constituents and apoptotic potential of Jordanian propolis extract against different cancer cell lines, propolis was extracted using methanol, hexane, and ethyl acetate and was fractionated using chromatographic methods. Cytotoxicity was assessed using MTT and LDH assays. The apoptotic potential was investigated using florescence microscopy, multicaspase assay, Annexin-V and dead cell assay, and cell cycle assay. The phytochemical constituents were analyzed using GC-MS. The methanol extract of propolis exhibited cytotoxic potential against all cell lines tested. The IC₅₀ values of the methanol extract were 47.4, 77.8, 91.2, and 145.0 ㎍/ml for HepG2, LoVo, MDAMB231, and MCF7 cell lines, respectively. The IC₅₀ values of the F1 fraction were 31.6 (MDAMB231), 38.9 (HepG2), 36.7 (LoVo) and 75.5 (MCF7) ㎍/ml. On further purification using thin-layer chromatography, the IC₅₀ values of the F1-3 fraction were found to be 84.31(HepG2), 79.2 (MCF7), 70.4 (LoVo), and 68.9 (MDAMB231) ㎍/ml, respectively. The anticancer potential of the F1 fraction was confirmed through the induction of apoptosis and cell cycle arrest at the G0/G1 phase. The GC-MS analysis of the F1 fraction revealed the presence of 3-methyl-4-isopropylphenol (29.44%) as a major constituent. These findings indicate the potential of propolis extract as a cancer therapy. However, further investigation is required to assess the acute and subacute toxicity of the most active fraction.

• Fisheries and Aquatic Sciences
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• v.26 no.8
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• pp.470-481
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• 2023

Algal overgrowth in shrimp culture ponds can affect the quality of the aquatic environment, thereby adversely affecting the shrimp and causing economic losses. The objective of this study was to evaluate the variation in phytoplankton composition in intensive shrimp ponds in Bac Lieu province, Vietnam. Phytoplankton samples were collected in three black tiger shrimp (Penaeus monodon) ponds and three whiteleg shrimp (Litopenaeus vannamei) ponds. The collected data were analyzed using SPSS and canonical correlation analysis softwares. In total, 75 species of phytoplankton were recorded in black tiger shrimp ponds and 64 species in whiteleg shrimp ponds. Diatoms had the highest species diversity with 29-30 species (39%-47%), followed by green algae with 9-19 species (14%-25%); species numbers of other phyla varied from 5-12 (8%-16%). The total number of phytoplankton species throughout the study varied from 34-50 species. Algal density was relatively high and ranged from 497,091-2,229,500 ind./L and 1,301,134-2,237,758 ind./L in black tiger shrimp and whiteleg shrimp ponds, respectively. The diatom density tended to increase during the final stage of the production cycle in black tiger shrimp ponds. Blue-green algae and dinoflagellates also increased in abundance at the end of the cycle, which can affect shrimp growth. Diatoms were significantly positively correlated with pH, salinity, total ammonia nitrogen, and nitrate (NO₃^-) concentrations (p < 0.05). Blue-green algae and dinoflagellates were positively correlated with salinity, phosphate (PO₄^3-), and NO₃^-. Algal species diversity was lower in the whiteleg shrimp ponds than in the black tiger shrimp ponds. Several dominant algal genera were recorded in the shrimp ponds, including Nannochloropsis, Gyrosigma, Chaetoceros, Alexandrium, and Microcystis. The results of this study provide basic data for further investigations, and they contribute to the management of algae in brackish-water shrimp ponds.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.59 no.4
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• pp.749-753
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• 2010

We investigated the haze and the surface roughness of textured Si substrates etched by $XeF_2$ etching system with the etching parameters of $XeF_2$ pressure, etching time, and etching cycle. Here the haze was obtained as a function of wavelength from the measured reflectance. The haze of textured Si substrates was strongly affected by the etching parameter of etching cycle. The surface roughness of textured Si substrates was calculated with the haze and the scalar scattering theory at the wavelength of 800 nm. Then, the surface roughness was compared with that measured by atomic force microscope. The surce roughness obtained by two methods was changed with the similar tendency n terms of $XeF_2$ etching conditions.

• Journal of Energy Engineering
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• v.10 no.4
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• pp.357-362
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• 2001

A bench type ammonia-water absorber heat exchange cycle was tested by varying the system charging concentration, refrigerating valve opening and weak solution flow rate. It was observed that the cooling capacity was increased as the system charging concentration was increased. Optimum system charging concentration was found for the coolong capacity of the system. The opening rate of refrigerant expansion valve had a direct influence on the refrigerant sub-cooling at the condenser outlet. Optimum sub-cooling was found to be 0~4$^{\circ}C$. As the weak solution flow rate increased the concentration of strong solution and the evaporating pressure decreased. There existed a optimum weak solution flow rate which maximized the cooling capacity and COP.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 1999.05a
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• pp.21-26
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• 1999

In this study, to assess chip breaking characteristics of cold-drawn free machining steels, a newly developed non-dimensional parameter, chip breaking index, C/sub B/ has been adopted. And for comparison with free machining steels, chip breaking characteristics of conventional carbon steels were investigated. Properly controlled chips were produced with the C/sub B/ value of 0.05∼0.2, regardless of steel types. In case of cold-drawn free machining steels, however, cycle times of chip breaking are relatively shorter than those of conventional steels. And properly controlled chips were obtained from wider range of feed rate.

• BMB Reports
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• v.56 no.4
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• pp.209-215
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• 2023

Maintaining internal homeostasis and regulating innate behaviors are essential for animal survival. In various animal species, a highly conserved neuroendocrine system integrates sensory inputs and regulates physiological responses to environmental and internal changes. Diuretic hormones 44 and 31, which are homologs of mammalian corticotropin-releasing factor (CRF) and calcitonin gene-related peptide (CGRP), respectively, control body fluid secretion in Drosophila. These neuropeptides and their receptors have multiple physiological roles, including the regulation of body-fluid secretion, sleep:wake cycle, internal nutrient-sensing, and CO₂-dependent response. This review discusses the physiological and behavioral roles of DH44 and DH31 signaling pathways, consisting of neuroendocrine cells that secrete DH44 or DH31 peptides and their receptor-expressing organs. Further research is needed to understand the regulatory mechanisms of the behavioral processes mediated by these neuroendocrine systems.

• Transactions of the Korean hydrogen and new energy society
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• v.34 no.1
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• pp.83-89
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• 2023

In this study, a computer simulation work has been performed for the separation of electronic grade highly pure carbon dioxide more than 7 N purity through a cryogenic distillation process. For the cold utility as a cooling medium for a condenser of the cryogenic distillation column, propylene was utilized as a refrigerant in the vapor-recompression refrigeration cycle. Through this work, it was concluded that the cryogenic distillation column with two stage compression and refrigeration cycle were essential to obtain a highly-pure liquefied CO₂.

• Transactions of the Korean Society of Automotive Engineers
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• v.4 no.2
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• pp.221-229
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• 1996

The engine speed fluctuation at idle operation mainly comes from cyclic variation of combustion in SI engine. In the present study, engineering model that is representing the cyclic variation of combustion was proposed for the sub-model of the engine cycle simulation. From the observed behaviors of the mass burn rates, probability density functions for the parameters of Wiebe function were defined. The mass burn rate of each cycle is obtained by Monte Cralo perturbation method with the probability function. The simulation results shows that trends of cylinder pressure variation and imep distribution follow up with those of experimental results at idle condition.

• Proceedings of the KSR Conference
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• 2008.06a
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• pp.1097-1104
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• 2008

Life cycle costing is one of the most effective approaches for the cost analysis of long-term life products, like as railroad vehicle. Life cycle costing includes the cost of concept design, development, manufacture, operating, maintenance and disposal. Especially, life cycle costing in the railroad industry has been focused on the maintenance cost. In this paper, we investigated the standard, guide and maintenance information of railroad vehicle. For this purpose, we suggested the unique templates of railroad vehicle maintenance information. We also performed maintenance cost analysis on the some sub-system of railroad vehicle for the case study.

• Journal of Institute of Convergence Technology
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• v.3 no.2
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• pp.1-6
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• 2013

The ionic liquids are known to potential alternative solvents capable of replacing the commercial solvents in various processes including those in nuclear fuel cycle. As to the material, a number of studies have already reviewed the interesting results and addressed the spectroscopic as well as electrochemical behaviors of metal elements included in spent nuclear fuels. It has found that the important properties of metal ions in TBP dissolved ILs have led the development of alternative technologies to traditional solvent extraction processes. On the other hand, the electrochemical deposition of metal ions in ILs have been investigated for the application of the solvents to aqueous as well as to non-aqueous processes. In this work, a review on the application of ILs in nuclear fuel cycle is briefly presented to understand the notable researches on ILs focusing on aqueous processes.