• 제목/요약/키워드: structure prediction

검색결과 2,060건 처리시간 0.027초

USING AN ABSTRACTION OF AMINO ACID TYPES TO IMPROVE THE QUALITY OF STATISTICAL POTENTIALS FOR PROTEIN STRUCTURE PREDICTION

  • Lee, Jin-Woo
    • Journal of the Korean Society for Industrial and Applied Mathematics
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    • 제15권3호
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    • pp.191-199
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    • 2011
  • In this paper, we adopt a position specific scoring matrix as an abstraction of amino acid type to derive two new statistical potentials for protein structure prediction, and investigated its effect on the quality of the potentials compared to that derived using residue specific amino acid identity. For stringent test of the potential quality, we carried out folding simulations of 91 residue A chain of protein 2gpi, and found unexpectedly that the abstract amino acid type improved the quality of the one-body type statistical potential, but not for the two-body type statistical potential which describes long range interactions. This observation could be effectively used when one develops more accurate potentials for structure prediction, which are usually involved in merging various one-body and many-body potentials.

Minimally Complex Problem Set for an Ab initio Protein Structure Prediction Study

  • Kim RyangGug;Choi Cha-Yong
    • Biotechnology and Bioprocess Engineering:BBE
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    • 제9권5호
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    • pp.414-418
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    • 2004
  • A 'minimally complex problem set' for ab initio protein Structure prediction has been proposed. As well as consisting of non-redundant and crystallographically determined high-resolution protein structures, without disulphide bonds, modified residues, unusual connectivities and heteromolecules, it is more importantly a collection of protein structures. with a high probability of being the same in the crystal form as in solution. To our knowledge, this is the first attempt at this kind of dataset. Considering the lattice constraint in crystals, and the possible flexibility in solution of crystallographically determined protein structures, our dataset is thought to be the safest starting points for an ab initio protein structure prediction study.

비선형, 비정상 시계열 예측을 위한 RBF(Radial Basis Function) 회로망 구조 (RBF Network Structure for Prediction of Non-linear, Non-stationary Time Series)

  • 김상환;이종호
    • 대한전기학회논문지:전력기술부문A
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    • 제48권2호
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    • pp.168-175
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    • 1999
  • In this paper, a modified RBF(Radial Basis Function) network structure is suggested for the prediction of a time-series with non-linear, non-stationary characteristics. Coventional RBF network predicting time series by using past outputs sense the trajectory of the time series and react when there exists strong relation between input and hidden activation function's RBF center. But this response is highly sensitive to level and trend of time serieses. In order to overcome such dependencies, hidden activation functions are modified to react to the increments of input variable and multiplied by increment(or dectement) for prediction. When the suggested structure is applied to prediction of Macyey-Glass chaotic time series, Lorenz equation, and Rossler equation, improved performances are obtained.

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An Optimized User Behavior Prediction Model Using Genetic Algorithm On Mobile Web Structure

  • Hussan, M.I. Thariq;Kalaavathi, B.
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제9권5호
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    • pp.1963-1978
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    • 2015
  • With the advancement of mobile web environments, identification and analysis of the user behavior play a significant role and remains a challenging task to implement with variations observed in the model. This paper presents an efficient method for mining optimized user behavior prediction model using genetic algorithm on mobile web structure. The framework of optimized user behavior prediction model integrates the temporary and permanent register information and is stored immediately in the form of integrated logs which have higher precision and minimize the time for determining user behavior. Then by applying the temporal characteristics, suitable time interval table is obtained by segmenting the logs. The suitable time interval table that split the huge data logs is obtained using genetic algorithm. Existing cluster based temporal mobile sequential arrangement provide efficiency without bringing down the accuracy but compromise precision during the prediction of user behavior. To efficiently discover the mobile users' behavior, prediction model is associated with region and requested services, a method called optimized user behavior Prediction Model using Genetic Algorithm (PM-GA) on mobile web structure is introduced. This paper also provides a technique called MAA during the increase in the number of models related to the region and requested services are observed. Based on our analysis, we content that PM-GA provides improved performance in terms of precision, number of mobile models generated, execution time and increasing the prediction accuracy. Experiments are conducted with different parameter on real dataset in mobile web environment. Analytical and empirical result offers an efficient and effective mining and prediction of user behavior prediction model on mobile web structure.

Analysis of structural dynamic reliability based on the probability density evolution method

  • Fang, Yongfeng;Chen, Jianjun;Tee, Kong Fah
    • Structural Engineering and Mechanics
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    • 제45권2호
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    • pp.201-209
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    • 2013
  • A new dynamic reliability analysis of structure under repeated random loads is proposed in this paper. The proposed method is developed based on the idea that the probability density of several times random loads can be derived from the probability density of single-time random load. The reliability prediction models of structure based on time responses under several times random loads with and without strength degradation are obtained by using the stress-strength interference theory and probability density evolution method. The resulting differential equations in the prediction models can be solved by using the forward finite difference method. Then, the probability density functions of strength redundancy of the structures can be obtained. Finally, the structural dynamic reliability can be calculated using integral method. The efficiency of the proposed method is demonstrated numerically through a speed reducer. The results have shown that the proposed method is practicable, feasible and gives reasonably accurate prediction.

뉴로-퍼지 모델을 이용한 단기 전력 수요 예측시스템 (Short-Term Electrical Load Forecasting using Neuro-Fuzzy Models)

  • 박영진;심현정;왕보현
    • 대한전기학회논문지:전력기술부문A
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    • 제49권3호
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    • pp.107-117
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    • 2000
  • This paper proposes a systematic method to develop short-term electrical load forecasting systems using neuro-fuzzy models. The primary goal of the proposed method is to improve the performance of the prediction model in terms of accuracy and reliability. For this, the proposed method explores the advantages of the structure learning of the neuro-fuzzy model. The proposed load forecasting system first builds an initial structure off-line for each hour of four day types and then stores the resultant initial structures in the initial structure bank. Whenever a prediction needs to be made, the proposed system initializes the neuro-fuzzy model with the appropriate initial structure stored and trains the initialized model. In order to demonstrate the viability of the proposed method, we develop an one hour ahead load forecasting system by using the real load data collected during 1993 and 1994 at KEPCO. Simulation results reveal that the prediction system developed in this paper can achieve a remarkable improvement on both accuracy and reliability compared with the prediction systems based on multilayer perceptrons, radial basis function networks, and neuro-fuzzy models without the structure learning.

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Fast Prediction Mode Decision in HEVC Using a Pseudo Rate-Distortion Based on Separated Encoding Structure

  • Seok, Jinwuk;Kim, Younhee;Ki, Myungseok;Kim, Hui Yong;Choi, Jin Soo
    • ETRI Journal
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    • 제38권5호
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    • pp.807-817
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    • 2016
  • A novel fast algorithm is suggested for a coding unit (CU) mode decision using pseudo rate-distortion based on a separated encoding structure in High Efficiency Video Coding (HEVC). A conventional HEVC encoder requires a large computational time for a CU mode prediction because prediction and transformation procedures are applied to obtain a rate-distortion cost. Hence, for the practical application of HEVC encoding, it is necessary to significantly reduce the computational time of CU mode prediction. As described in this paper, under the proposed separated encoder structure, it is possible to decide the CU prediction mode without a full processing of the prediction and transformation to obtain a rate-distortion cost based on a suitable condition. Furthermore, to construct a suitable condition to improve the encoding speed, we employ a pseudo rate-distortion estimation based on a Hadamard transformation and a simple quantization. The experimental results show that the proposed method achieves a 38.68% reduction in the total encoding time with a similar coding performance to that of the HEVC reference model.

항공기 구조물의 체결용 HOLE을 COLD WORKING 할때 생성되는 잔류응력의 영향연구 (A Study on Effects of the Residual Stresses Around Cold Working Hole of the Aircraft Structure)

  • 강수준;최청호
    • 한국군사과학기술학회지
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    • 제2권1호
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    • pp.101-109
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    • 1999
  • 본 논문은 항공기 구조물의 체결용 홀(hole)을 냉간가공(cold working)할때 홀주변에 생성되는 잔류응력이 균열발생 수명과 균열성장에 미치는 영향을 연구한 내용이다. 항공기용 재료로 많이 사용되는 AL7075-T6 및 AL2024-T3 시편으로 측정된 계수를 Morrow의 수명예측식에 적용하여 수정된 냉간가공(cold working)에 관한 수명예측식을 제안하였다. 수정된 계산식으로 얻어진 수명예측값과 실험에 의하여 이미 알려진 값이 비교적 일치함을 보여 이러한 재료에 대하여 수명예측이 가능함을 보였다. 균열성장 예측을 위해 역시 AL7075-T6 재료에 대하여 가중함수(weight function)방법으로 잔류응력 세기계수를 구하여 Forman의 균열성장 예측식을 수정하여 계산 한 결과 이 또한 알려진 실험값과 거의 일치함을 보여 실험에 사용한 재료의 구조물 해석에 유용 할 것으로 보인다. 본 연구는 항공기용 구조물의 홀주변을 냉간가공 (cold working)할 때 생성되는 잔류응력의 영향을 연구하는 기초적인 단계 일 뿐이며, 향후 실제 정비현장에서 적용 할 수 있는 대상분야와 연구 방향에 대한 보다 심층적 연구가 필요함을 보인다.

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Protein Disorder Prediction Using Multilayer Perceptrons

  • Oh, Sang-Hoon
    • International Journal of Contents
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    • 제9권4호
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    • pp.11-15
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    • 2013
  • "Protein Folding Problem" is considered to be one of the "Great Challenges of Computer Science" and prediction of disordered protein is an important part of the protein folding problem. Machine learning models can predict the disordered structure of protein based on its characteristic of "learning from examples". Among many machine learning models, we investigate the possibility of multilayer perceptron (MLP) as the predictor of protein disorder. The investigation includes a single hidden layer MLP, multi hidden layer MLP and the hierarchical structure of MLP. Also, the target node cost function which deals with imbalanced data is used as training criteria of MLPs. Based on the investigation results, we insist that MLP should have deep architectures for performance improvement of protein disorder prediction.