• Journal of radiological science and technology
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• v.47 no.2
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• pp.125-135
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• 2024

This study analysed the factors that predict and influence heart disease through key indicators related to changes in left atrial and left ventricular size. Measurements recommended by the American Society of Echocardiography were used, and the influence of variables was assessed using multiple regression analysis. The results showed that left atrial volume index(LAVI) was significantly different by age, obesity, diabetes, hypertension, dyslipidaemia, and left ventricular relaxation dysfunction(p<0.05). Left ventricular mass index(LVMI) was significantly different according to age, body mass index, hypertension, diabetes, dyslipidaemia, and left ventricular relaxation dysfunction(p<0.05). Increases in LVMI and relative ventricular wall thickness(RWT) were associated with changes in LAVI(p<0.05). Age, systolic blood pressure, increased LAVI, and RWT influenced changes in LVMI, and left ventricular dysfunction was analysed as an influencing factor for both changes in LAVI and LVMI. Therefore, changes in left atrial and left ventricular size are indicators for early diagnosis and prevention of heart disease, and it is necessary to carefully observe structural changes in the heart and actively manage risk factors for the prevention and management of heart disease.

• Journal of the Korea institute for structural maintenance and inspection
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• v.15 no.2
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• pp.136-143
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• 2011

The oversized and slotted holes are frequently required for the built-up in construction sites. The foreign provisions specify the reduction of the slip load subjected to the size of bolt holes and the direction of load. There are no domestic building codes and researches on the bolt holes. Therefore, it is necessary to evaluate a change of joint strength quantitatively according to the bolt-hole size and surface condition by means of experiment. This study was conducted to evaluate the slip load subjected to the size of bolt holes, and measured on a change of clamping force of high strength bolts during 168 and 800 hours to analyze the trend of relaxation after fastening bolts. Torque shear bolts defined on KS B 2819 was used for the specimen. Test results exhibit that the variation on the slip load of the others was below 10% by contrast with the standard hole and the highest rate of relaxation was 2.66% of the initial clamping force at the case of the long-slotted hole of 2.5D.

• Journal of the Korea institute for structural maintenance and inspection
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• v.25 no.4
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• pp.75-82
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• 2021

The objective of this study is to examine the loss of prestressing stress in the developed prestressing reinforcing units using steel bar and pipe (SP). The main parameters were the reinforcing bar type, the magnitude of prestressed force, and prestressing method. The test results showed that the loss of prestressing stress for SP was highest in the initial prestressing step, which was higher for the compression introduction typed specimens than tension introduction typed specimens. The loss of prestressing stress of SP made with P800 was 1.6% for the compression introduction typed specimen with 0.8f_y, which was lowest than the other specimens. Meanwhile, the relaxation of SP with the respect to the time ranged between 0.4 and 1.9%, irrespective of SP material type, the magnitude of prestressed force, and prestressing method. These values were less than 2.5%, which is the maximum value for the relaxation of prestressed reinforcing steel bars in design codes. Consequently, considering the loss of stress developed in the initial prestressing step, the developed SP material type, prestressing introduction method, and magnitude are recommended to be P800, compression introduction type, and 0.8f_y.

• Journal of Korean Society of Steel Construction
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• v.12 no.5 s.48
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• pp.605-615
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• 2000

Cerebellar model articulation controller (CMAC) is introduced and used for the identification of structural dynamic model. CMAC has fascinating features in learning speed. It can learn structural response within a few seconds. Therefore it is suitable for the real time identification structures. Real time identification is required in the control of structure which may be damaged or undergo severe change in mechanical properties due to shrinkage or relaxation etc. In numerical examples, it is shown that CMAC trained with the dynamic response of three-story building can predict responses under not trained earthquakes with allowable error. Finally, CMAC has great potential in structural and control engineering.

• Structural Engineering and Mechanics
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• v.20 no.6
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• pp.673-693
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• 2005

A general step-by-step simulation for the time-dependent analysis of segmentally-erected prestressed concrete box-girder bridges is presented. A three dimensional finite-element model for the balanced-cantilever construction of segmental bridges, including effects of the load history, material nonlinearity, creep, shrinkage, and aging of concrete and the relaxation of prestressing steel was developed using ABAQUS software. The models included three-dimensional shell elements to model the box-girder walls and Rebar elements representing the prestressing tendons. The step-by-step procedure allows simulating the construction stages, effects of time-dependent deformations of materials and changes in the structural system of the bridges. The structural responses during construction and throughout the service life were traced. A comparison of the developed computer simulation with available experimental results was conducted and good agreement was found. Deflection of the bridge deck, changes in stresses and strains and the redistribution of internal forces were calculated for different examples of bridges, built by the balanced-cantilever method, over thirty-year duration. Significant time-dependent effects on the bridge deflections and redistribution of internal forces and stresses were observed. The ultimate load carrying capacities of the bridges and the behavior before collapse were also determined. It was observed that the ultimate load carrying capacity of such bridges decreases with time as a result of time-dependent effects.

• BMB Reports
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• v.34 no.1
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• pp.1-7
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• 2001

Structural and physical properties of type wild type and various selected mutants of the vnd/NK-2 homeodomain, the protein product of the homeobox, and the implication in genetic disease are reviewed. The structure, dynamics and thermodynamics have been Investigated by NMR and by calorimetry. The interactions responsible for the nucleotide sequence-specific binding of the homeodomain to its consensus DNA binding site have been identified. There is a strong correlation between significant structural alterations within the homeodomain or its DNA complex and the appearance of genetic disease. Mutations in positions known to be important in genetic disease have been examined carefully For example, mutation of position 52 of vnd/NK-2 results in a significant structural modification and mutation of position 54 alters the DNA binding specificity and amity The $^{15}N$ relaxation behavior and heteronuclear Overhauser effect data was used to characterize and describe the protein backbone dynamics. These studies were carried out on the wild type and the double mutant proteins both in the free and in the DNA bound states. Finally, the thermodynamic properties associated with DNA binding are described for the vnd/NK-2 homeodomain. These thermodynamic measurements reinforce the hypothesis that water structure around a protein and around DNA significantly contribute to the protein-DNA binding behavior. The results, taken together, demonstrate that structure and dynamic studies of proteins combined with thermodynamic measurements provide a significantly more complete picture of the solution behavior than the individual studies.

• Structural Engineering and Mechanics
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• v.43 no.6
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• pp.739-759
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• 2012

The tailoring optimization technique recently developed by the author for improving structural response and energy absorption of composites is extended to sandwich shells using a previously developed zig-zag shell model with hierarchic representation of displacements. The in-plane variation of the stiffness properties of plies and the through-the thickness variation of the core properties are determined solving the Euler-Lagrange equations of an extremal problem in which the strain energy due to out-of-plane strains and stresses is minimised, while that due to their in-plane counterparts is maximised. In this way, the energy stored by unwanted out-of-plane modes involving weak properties is transferred to acceptable in-plane modes. As shown by the numerical applications, the critical interlaminar stress concentrations at the interfaces with the core are consistently reduced without any bending stiffness loss and the strength to debonding of faces from the core is improved. The structural model was recently developed by the author to accurately describe strain energy and interlaminar stresses from the constitutive equations. It a priori fulfills the displacement and stress contact conditions at the interfaces, considers a second order expansion of Lame's coefficients and a hierarchic representation that adapts to the variation of solutions. Its functional d.o.f. are the traditional mid-plane displacements and the shear rotations, so refinement implies no increase of the number of functional d.o.f. Sandwich shells are represented as multilayered shells made of layers with different thickness and material properties, the core being treated as a thick intermediate layer.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.11 no.4
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• pp.72-81
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• 2012

This study investigates structural, fatigue and modal analyses at bicycle suspension seat post. When weight is applied to the saddle, models 1 and 2 have the weakest strength at the part connected with saddle. And model 2 is greater total deformation and equivalent stress than model 1. Among the cases of nonuniform fatigue loads at models 1 and 2, 'SAE bracket history' with the severest change of load becomes most unstable but 'Sample history' becomes most stable. In case of 'Sample history' with the average stress of 0 to $-10^4MPa$ and the amplitude stress of 0 to $10^4MPa$, the possibility of maximum damage becomes 4%. This stress state can be shown with 5 to 7times more than the damage possibility of 'SAE bracket history' or 'SAE transmission'. Model 1 has better impulse relaxation and passenger sensitivity than model 2. The structural result of this study can be effectively utilized with the design of bicycle suspension seat post by investigating prevention and durability against its damage.

• Steel and Composite Structures
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• v.17 no.4
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• pp.405-429
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• 2014

In this paper, it is aimed to determine the structural behavior of suspension bridges considering construction stages and different soil conditions. Bosporus Suspension Bridge connecting the Europe and Asia in Istanbul is selected as an example. Finite element model of the bridge is constituted using SAP2000 program considering existing drawings. Geometric nonlinearities are taken into consideration in the analysis using P-Delta large displacement criterion. The time dependent material strength of steel and concrete and geometric variations is included in the analysis. Time dependent material properties are considered as compressive strength, aging, shrinkage and creep for concrete, and relaxation for steel. To emphases the soil condition effect on the structural behavior of suspension bridges, each of hard, medium and soft soils are considered in the analysis. The structural behavior of the bridge at different construction stages and different soil conditions has been examined. Two different finite element analyses with and without construction stages are carried out and results are compared with each other. At the end of the analyses, variation of the displacement and internal forces such as bending moment, axial forces and shear forces for bridge deck and towers are given in detail. Also, displacement and stresses for bridge foundation are given with detail. It can be seen from the analyses that there are some differences between both analyses (with and without construction stages) and the results obtained from the construction stages are bigger. It can be stated that the analysis without construction stages cannot give the reliable solutions. In addition, soil condition have effect on the structural behavior of the bridge. So, it is thought that construction stage analysis using time dependent material properties, geometric nonlinearity and soil conditions effects should be considered in order to obtain more realistic structural behavior of suspension bridges.

• Journal of Photoscience
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• v.9 no.2
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• pp.106-109
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• 2002

Archaeal rhodopsins possess retinal molecule as their chromophores, and their light-energy and light-signal conversions are triggered by all-trans to 13-cis isomerization of the retinal chromophore. Relaxation through structural changes of protein then leads to functional processes, proton pump in bacteriorhodopsin (bR) and transducer activation in phoborhodopsin (pR). It is known that sensory rhodopsins can pump protons in the absence of their transducers. Thus, there should be common and specific features in their protein structural changes for function. In this paper, our r ecent studies on pR from Natronobacterium pharaonis (ppR) by means of low-temperature Fourier-transform infrared (FTIR) spectroscopy are compared with those of bR. In particular, protein structural changes upon retinal photoisomerization are studied. Comparative investigation of ppR and bR revealed the similar structures of the polyene chain of the chromophore and water-containing hydrogen-bonding network, whereas the structural changes upon photoisomerization were more extended in ppR than in bR. Extended protein structural changes were clearly shown by the assignment of the C=O stretch of Asnl05. FTIR studies of a ppR mutant with the same retinal binding site as in bR revealed that the Schiff base region is important to determine their colors.