• 사상체질의학회지
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• 제16권2호
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• pp.58-64
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• 2004

1. Objectives However there was a report that dyspepsia occurs more frequently in Soeumin, there has not been any clinical research if structural changes such as gastritis occurs differently according to Sasang Constitution. So in this research, we investigated to find out if there are differences in the degree and types of gastritis and gastrointestinal symptoms according to Sasang Constitution and gender difference. 2. Methods Subjects were 30 men and 38 women, who had visited Kyung-Hee Medical Center for physical examination and took gastroscopy and differential diagnosis of Sasang Constitution in March, 2003. We investigated the degree and types of gastritis and gastrointestinal symptoms. 3. Results and conclusions Gender difference han no relation with types of gastritis, but had significant relation with the degree of gastritis and gastrointestinal symptoms. But Sasang Constitution had no significant relation with the degree and types of gastritis and gastrointestinal symptoms.

• Smart Structures and Systems
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• 제20권6호
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• pp.683-696
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• 2017

In this study, the reliability of nonlinear ultrasonic modulation based fatigue crack detection is improved using a feature-level data fusion approach. When two ultrasonic inputs at two distinct frequencies are applied to a specimen with a fatigue crack, modulation components at the summation and difference of these two input frequencies appear. First, the spectral amplitudes of the modulation components and their spectral correlations are defined as individual features. Then, a 2D feature space is constructed by combining these two features, and the presence of a fatigue crack is identified in the feature space. The effectiveness of the proposed fatigue crack detection technique is experimentally validated through cyclic loading tests of aluminum plates, full-scale steel girders and a rotating shaft component. Subsequently, the improved reliability of the proposed technique is quantitatively investigated using receiver operating characteristic analysis. The uniqueness of this study lies in (1) improvement of nonlinear ultrasonic modulation based fatigue crack detection reliability using feature-level data fusion, (2) reference-free fatigue crack diagnosis without using the baseline data obtained from the intact condition of the structure, (3) application to full-scale steel girders and shaft component, and (4) quantitative investigation of the improved reliability using receiver operating characteristic analysis.

• 한국항공우주학회지
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• 제46권9호
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• pp.767-773
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• 2018

최신 항공기에는 항공기의 건전성을 확인하기 위한 진동데이터 수집 장비가 장착되는 경우가 많다. 이러한 장비를 통해 수집되는 진동 데이터의 분석은 항공기 설계에 정통한 전문가에 의존하는 것이 일반적이며, 설계 분석을 통해 일반 사용자를 위한 대표적이고 객관적인 결함식별 기준을 제시하는 것은 쉽지 않다. 본 논문에서 우리는 기존의 항공기 설계분석 방법이 아닌, 운용 중 수집되는 방대한 양의 진동 데이터에 주성분 분석을 적용하는 방식으로 기동 및 결함유형 식별이 가능한지를 확인하였다. 이를 위해 국내 육군에서 실운용중인 항공기의 진동 데이터를 실측하여 기동 및 결함 유형별로 분류하였고, 분류된 데이터에 주성분 분석 기법을 적용하였다. 그 결과 설계 분석을 하지 않고도 운용 데이터 분석만을 통하여 일반 사용자들을 위한 기동/결함유형 식별 도구의 개발이 가능함이 확인되었다.

• 한국산학기술학회논문지
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• 제15권2호
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• pp.940-951
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• 2014

본 연구는 요양병원의 간호 인력의 간호행위 수행 실태를 파악한 조사연구이다. 연구 자료는 설문지를 이용하여 15곳의 요양병원에 근무하는 131명의 간호사를 대상으로 2013년 3월 7일부터 6월 30일까지 수집하였다. 자료 분석은 SPSS 17.0프로그램을 이용하여 기술통계 및 t-test, ANOVA를 시행하였다. '간호진단하기', '간호목표 설정하기', '환자평가표 작성'을 제외한 88항목의 간호행위를 다양한 범위 내에서 간호사와 간호조무사가 함께 수행하고 있는 것으로 나타났으며 기관의 총 환자 수와 간호사 수에 따라 간호조무사의 간호업무 수행정도는 유의한 차이가 나타났다(p<.001). 따라서 요양병원의 간호업무 중 위임할 수 있는 업무와 위임할 수 없는 업무를 분류하고, 위임에 대한 알고리즘 개발이 필요하며, 위임에 대한 법적, 제도적 규정을 마련할 필요가 있다.

• Korean Journal of Acupuncture
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• 제29권1호
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• pp.47-55
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• 2012

Objectives : The aim of this study was to understand the meaning of meridian in "Woegwasimbeopyogyeol (WGS)" of "The Golden Mirror of Medicine (GMM)". Methods : We compared the meaning of meridian in WGS with in Jagusimbeopyogyeol (JGS) of GMM. Results : Objectivity and clearness is obtained by inserting the meridian and collateral diagram and the partially expanded diagram in WGS and JGS. The meridian song (a quatrain with seven) in WGS is placed at the beginning of the chapter, indicating its importance. Kihyeoldaso of 12 meridians is detailed in WGS, so as to reduce the harmful effect when doctors diagnose, treat and prognose. It is important to understand the meaning of meridian When doctors treat carbunculosis. The symptoms of a disease is classified by parts and shown in diagram, which can play an important role in diagnosis. Conclusions : The WGS follows the meanings of meridian and the complementary structure in JGS.

• Journal of Genetic Medicine
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• 제7권2호
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• pp.111-118
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• 2010

염색체 microarray 검사는 유전체 전체를 한번에 검색하여 초현미경적인 염색체 이상을 매우 정밀하고 정확하게 검출할 수 있다. 외국에서는 현재 자주 활용되는 임상 진단 검사로 자리잡았고, 염색체 검사 또는 표적 부위를 검출하는 FISH 검사나 PCR 기반의 분자유전학적 방법을 대체하고 있다. 최근 발표된 consensus 들은 염색체 microarray 검사를 비특이적인 다발성 기형, 발달지연 또는 정신지체, 자폐증상질환의 환자에서는 염색체 검사보다 먼저 시행할 수 있는 검사로 제안하였다. 염색체 microarray 검사는 핵형 분석에서 검출된 염색체 불균형을 검증하기 위해 염색체 검사에 보조적으로 활용할 수 있고, 염색체 이상에 대한 보다 정확하고 종합적인 분석이 가능하다. 그러나 염색체 microarray 검사는 균형재배열의 염색체 이상과 low-level 모자이시즘을 검출하기 어렵고, 임상적 중요성이 불명확한 CNV에 대한 해석과 검사비용이 고가라는 한계점이 있다. 이러한 이유로 인해 현재로서는 염색체 microarray 검사가 산전 진단 목적으로는 고식적인 염색체 검사를 대신할 수는 없다는 의견이다. 임상검사실에서 염색체 microarray 검사 시행 시, 유전학적 및 세포유전학적 지식과 경험이 결과 분석과 해석 과정에서 요구되며, 적절한 검증 과정 단계와 유전상담이 동반되어야 한다.

• 대한임상독성학회지
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• 제8권2호
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• pp.79-87
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• 2010

Purpose: The previous studies on $H_1$ antihistamine overdose have generally been limited to cases of acute doxylamine succinate (DS) poisoning, yet there have been some studies on diphenhydramine (DPH) overdosing. But many clinicians consider the two drugs to be very similar and to have similar ingredients. The purpose of this study was to clarify the toxicologic characteristics and clinical outcomes between DS and DPH poisoning/overdose. Methods: We reviewed the medical and intensive care records of the patients with acute DS or DPH poisoning and who admitted to our emergency department from January 2008 and April 2010. We collected patient information regarding the features of the poisoning and the clinical and demographic characteristics. The patients were assessed for the clinical outcomes, the GCS, the PSS (Poisoning Severity Score) and the SOFA (Sequential Organ Failure Assessment). Results: Fifty seven patients (45 cases of DS poisoning and 12 cases of DPH poisoning) were enrolled. Compared with the DS group, the DPH group had higher incidences of intubation, serious mental change, QTc prolongation and ECG conduction abnormality (p=0.041, <0.001, 0.014 and 0.044, respectively). The DPH group had a higher PSS and a longer ICU stay. The peak CPK time and the CPK normalization time were longer for the patients with rhabdomyolysis due to DS poisoning. Conclusion: Two common $H_1$ antihistamines, doxylamine and diphenhydramine, are in the same ethanolamine-structural class, but the toxico-clinical outcomes are different according to many aspects. Therefore, clinicians could take a careful approach for the differential diagnosis and management between DS and DPH poisoning.

• Structural Engineering and Mechanics
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• 제71권1호
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• pp.57-63
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• 2019

During the last two decades, much joint research regarding vibration based methods has been done, leading to developing various algorithms and techniques. These algorithms and techniques can be divided into modal methods and signal methods. Although modal methods have been widely used for health monitoring and damage detection, signal methods due to higher efficiency have received considerable attention in various fields, including aerospace, mechanical and civil engineering. Signal-based methods are derived directly from the recorded responses through signal processing algorithms to detect damage. According to different signal processing techniques, signal-based methods can be divided into three categories including time domain methods, frequency domain methods, and time-frequency domain methods. The frequency domain methods are well-known and interest in using them has increased in recent years. To determine dynamic behaviours, to identify systems and to detect damages of bridges, different methods and algorithms have been proposed by researchers. In this study, a new algorithm to detect seismic damage in the bridge's piers is suggested. To evaluate the algorithm, an analytical model of a bridge with simple spans is used. Based on the algorithm, before and after damage, the bridge is excited by a sine force, and the piers' responses are measured. The dynamic specifications of the bridge are extracted by Power Spectral Density function. In addition, the Least Square Method is used to detect damage in the bridge's piers. The results indicate that the proposed algorithm can identify the seismic damage effectively. The algorithm is output-only method and measuring the excitation force is not needed. Moreover, the proposed approach does not need numerical models.

• 대한의용생체공학회:의공학회지
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• 제42권3호
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• pp.80-85
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• 2021

We developed a model to classify the absence of cervical cancer using deep learning from the cervical image to which the histogram equalization algorithm was applied, and to compare the performance of each model. A total of 4259 images were used for this study, of which 1852 images were normal and 2407 were abnormal. And this paper applied Image Sharpening(IS), Histogram Equalization(HE), and Contrast Limited Adaptive Histogram Equalization(CLAHE) to the original image. Peak Signal-to-Noise Ratio(PSNR) and Structural Similarity index for Measuring image quality(SSIM) were used to assess the quality of images objectively. As a result of assessment, IS showed 81.75dB of PSNR and 0.96 of SSIM, showing the best image quality. CLAHE and HE showed the PSNR of 62.67dB and 62.60dB respectively, while SSIM of CLAHE was shown as 0.86, which is closer to 1 than HE of 0.75. Using ResNet-50 model with transfer learning, digital image-processed images are classified into normal and abnormal each. In conclusion, the classification accuracy of each model is as follows. 90.77% for IS, which shows the highest, 90.26% for CLAHE and 87.60% for HE. As this study shows, applying proper digital image processing which is for cervical images to Computer Aided Diagnosis(CAD) can help both screening and diagnosing.

• Journal of Hospice and Palliative Care
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• 제24권4호
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• pp.214-225
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• 2021

Purpose: This study reviewed screening and assessment tools that are used to measure delirium in patients with cancer in hospice and palliative care settings and examined their psychometric properties. Methods: Four databases were searched for studies using related search terms (delirium, tools, palliative care, cancer, and others). The inclusion criteria were a) studies that included screening/assessment tools for measuring delirium in cancer patients receiving hospice/palliative care, and b) studies published in English or Korean. The exclusion criteria were a) studies that were conducted in an intensive care setting, and b) case studies, qualitative studies, systematic reviews, or meta-analyses. Results: Out of the 81 studies identified, only 10 examined the psychometric properties of tools for measuring delirium, and 8 tools were ultimately identified. The psychometric properties of the Memorial Delirium Assessment Scale (MDAS) were the most frequently examined (n=5), and the MDAS showed good reliability, concurrent validity, and diagnostic accuracy. The Delirium Rating Scale had good reliability and diagnostic accuracy. The Delirium Rating Scale-Revised 98 also showed good reliability and structural validity, but its diagnostic performance was not examined in hospice/palliative care settings. The Nursing Delirium Screening Scale showed relatively low diagnostic accuracy. Conclusion: The MDAS showed evidence of being a valid assessment tool for assessing delirium in patients with cancer in palliative care. Few studies examined the diagnostic performance of delirium tools. Therefore, further studies are needed to examine the diagnostic performance of screening/assessment tools for the optimal detection of delirium in patients with cancer in hospice/palliative care.