• Title/Summary/Keyword: stripping

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A Case of Naturally Acquired Cheyletiellosis in a Rabbit: Therapeutic Trial of Selamectin (애완토끼에서 발생한 Cheyletiellosis 피부염에 대한 selamectin 치료 1례)

  • Hoh Woo-pil;Oh Won-Seok;Oh Hynn-ho;Lee Kenn-woo;Eom Ki-dong;Oh Tae-ho
    • Journal of Veterinary Clinics
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    • v.22 no.1
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    • pp.56-59
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    • 2005
  • An about 5-month-old, female rabbit was presented with pruritus, alopecia and mucopurulent ocular discharge. On physical examination mild to moderate scales on whole body were observed. Dermatological lesions such as alopecia, erythema, papules, pustules and crusts were observed in the eyelids, nose, inner pinna, medial sites of four feet, metacarpal and metatarsal areas, and cranial site of left stifle joint. Also, mild conjunctivitis, blepharitis and keratitis were found. For extensive dermatologic diagnostic evaluation skin scraping, tape stripping, impression smear, combing, wood' light, bacterial culture and fungal culture were performed. Finally, Cheyletiella spp. was found by combing. Many heterophils and eosinophills were appeared in impression smear. The result of fungal culture was negative. Pasteurella spp was cultured. Definitive diagnosis of Cheyletiellosis and secondary Pasteurella spp infection were established. The rabbit was treated with 6 mg/kg of selamectin topically every two weeks and restricted in cage for one month. During one month of initial treatment, clinical signs such as pruritus, alopecia, scales, papules, pustules and crusts were remarkably improved. However, in spite of good therapeutic response of selamectin the rabbit was dead suddenly at 22 days after second administration of selamectin. This case showed that selamectin was possibly effective for cheyletiellosis in rabbit; safety of selamectin for rabbit was not identified.

Feasibility about the Direct Measurement of 226Ra Using the Gamma-Ray Spectrometry (감마분광분석을 이용한 226Ra의 직접 측정방법에 대한 적용성 평가)

  • Ji, Young-Yong;Chung, Kun Ho;Lim, Jong-Myoung;Kim, Change-Jong;Jang, Mee;Kang, Mun Ja;Park, Sang Tae;Woo, Zuhee;Koo, Boncheol;Seo, Bokyun
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.12 no.2
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    • pp.97-105
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    • 2014
  • In the case of the direct measurement of $^{226}Ra$ using a HPGe gamma-ray spectrometer, the interference between gammarays with 186.21 keV of $^{226}Ra$ and 185.7 keV of $^{235}U$ should be corrected to calculate the net peak area in the energy spectrum. In general, it is very difficult to conduct peaks stripping with difference of about 0.5 keV, although a HPGe with the superior resolution is applied and the maximum channels is applied to the spectrometer. In this study, several interference correction techniques in the direct measurement were surveyed to evaluate the feasibility for the measurement of $^{226}Ra$ using the gamma-ray spectrometery. Applying the interference corrections to the analysis of raw materials and by-products, the method validation for the direct measurement of $^{226}Ra$ was conducted by evaluating the measurement uncertainty, linearity, and range. As a result, the optimum method of the interference correction was selected by comparing with the indirect measurement of which progenies of $^{226}Ra$, such as $^{214}Pb$ and $^{214}Bi$, were analyzed in the secular equilibrium state.

Performance Evaluation of MAC Protocols Considering Various Input Traffic in WDM Metro Ring Networks (WDM 메트로 링 망에서 다양한 입력 트래픽을 고려한 MAC 프로토콜의 성능분석)

  • Lee, Kyu-Jeong;So, Won-Ho
    • Proceedings of the Korean Information Science Society Conference
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    • 2006.10d
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    • pp.24-29
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    • 2006
  • 본 논문에서는 광대역 통신 방송 융합 서비스 제공을 고려한 WDM 메트로 링 망을 위한 매체 접근 제어(Medium Access Control; MAC) 프로토콜의 성능을 분석한다. 현재 인터넷은 통신 방송 융합 망으로 진화하고 있으며 다양한 트래픽 특성을 갖는 서비스가 액세스 망에서 메트로 망으로 유입되고 있다. 그러나 기존 메트로 망의 MAC 프로토콜은 이러한 망 환경 변화를 고려하지 않고 단순하고 동일한 트래픽만을 고려하여 성능을 분석하였다. 따라서 본 논문에서는 메트로 링에 연결된 액세스 노드의 입력 트래픽을 Self-Similar와 Poisson 트래픽으로 분류하여 기존 MAC 프로토콜의 성능을 분석하고 평가한다. 메트로 링 망에 연결된 액세스 노드는 이 두 종류의 트래픽 중에서 하나를 망에 유입하며 채널을 공유하는 노드 수에 따라서 다양한 트래픽 환경이 고려된다. WDM 메트로 링망의 기본 MAC 프로토콜은 CSMA/CA(Carrier Sense Multiple Access with Collision Avoidance)이며, 패킷을 빈 슬롯에 전송하고 송신지에서 패킷을 제거하는 SS (Source-Stripping) 기반으로 운용된다. 본 논문에서는 SS 방식으로 생성된 빈 슬롯을 바로 패킷 전송에 이용하는 방식과 그렇지 않은 방식을 각각 1-Persistent와 non-Persistent로 분류하고 MAC 프로토콜을 분석하여 기존 방식의 장 단점을 비교한다. 또한 전송 공정성과 처리율을 같이 고려하여 적용할 수 있는 확률 기반 p-Persistent MAC 프로토콜도 분석하였으며 시뮬레이션을 통하여 각 프로토콜을 노드 처리율, 전송 지연, 패킷 손실률, 전송 공정성 관점에서 비교하고 평가한다.y 수행을 여러 서버로 분산처리하게 함으로써 성능에 대한 신뢰성을 향상 시킬 수 있는 Load Balancing System을 제안한다.할 때 가장 효과적인 라우팅 프로토콜이라고 할 수 있다.iRNA 상의 의존관계를 분석할 수 있었다.수안보 등 지역에서 나타난다 이러한 이상대 주변에는 대개 온천이 발달되어 있었거나 새로 개발되어 있는 곳이다. 온천에 이용하고 있는 시추공의 자료는 배제하였으나 온천이응으로 직접적으로 영향을 받지 않은 시추공의 자료는 사용하였다 이러한 온천 주변 지역이라 하더라도 실제는 온천의 pumping 으로 인한 대류현상으로 주변 일대의 온도를 올려놓았기 때문에 비교적 높은 지열류량 값을 보인다. 한편 한반도 남동부 일대는 이번 추가된 자료에 의해 새로운 지열류량 분포 변화가 나타났다 강원 북부 오색온천지역 부근에서 높은 지열류량 분포를 보이며 또한 우리나라 대단층 중의 하나인 양산단층과 같은 방향으로 발달한 밀양단층, 모량단층, 동래단층 등 주변부로 NNE-SSW 방향의 지열류량 이상대가 발달한다. 이것으로 볼 때 지열류량은 지질구조와 무관하지 않음을 파악할 수 있다. 특히 이러한 단층대 주변은 지열수의 순환이 깊은 심도까지 가능하므로 이러한 대류현상으로 지표부근까지 높은 지온 전달이 되어 나타나는 것으로 판단된다.의 안정된 방사성표지효율을 보였다. $^{99m}Tc$-transferrin을 이용한 감염영상을 성공적으로 얻을 수 있었으며, $^{67}Ga$-citrate 영상과 비교하여 더 빠른 시간 안에 우수한 영상을 얻을 수 있었다. 그러므로 $^{99m}Tc$-transierrin이 감염 병소의 영상진단에 사용될 수 있을 것으로 기대된

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Development of Integrated Wireless Sensor Network Device with Mold for Measurement of Concrete Temperature (콘크리트 온도 측정을 위한 거푸집 일체형 무선센서네트워크 장치 개발)

  • Lee, Sung Bok;Park, Seong Sik
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.16 no.5
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    • pp.129-136
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    • 2012
  • Temperature of fresh concrete can be effectively used to predict the strength of concrete being cured and make an informed decision for stripping the molds. A hygrothermograph and thermo-couple sensors that require an extensive wiring have been applied to measure a temperature of concrete at the early stage of the curing process on site. However, these methods have limits to provide the temperature data in real time due to harsh working environment including frequent cutting of wires. Therefore, this study is aiming at developing a device based on wireless sensor network to measure the temperature of concrete being cured in formwork. The result showed that the wireless sensor with probe type thermistor which is developed had the same temperature data compared to the existed wire type thermistor, and we confirmed the temperature history of concrete in real time for 28 days throughout the gateway by wireless network that collects the temperature data measured from specimens in laboratory. Also, the network device for transmission can be easily separated from the probe sensor part and reused consistently. If the wireless sensor network device developed uses in the field, the temperature management of concrete will be systematically conducted from at the early stage of the curing, and especially be effective for cold weather concrete construction. In addition, it will contribute to the establishment of advanced quality control system for concrete and productivity of supervisors on site will be increased in the future.

Extraction Behaviour of Np with DEHPA from the Low Nitric Acid Solution Containing Hydrogen Peroxide (과산화수소가 함유된 저산도 질산용액에서 DEHPA 추출제에 의한 Np의 추출거동)

  • Lee, E.H.;Yang, H.B.;Kim, K.K.;Lim, J.K.;Yoo, J.H.
    • Applied Chemistry for Engineering
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    • v.7 no.4
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    • pp.707-714
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    • 1996
  • Extraction behaviour of Np with DEHPA(di-(2-ethyhexyl)Phosphoric acid) from the low nitric acid solution(below 1M $HNO_3$) containing $H_2O_2$ as a reducing agent was studied at a batch system in order to establish the conditions of extraction and stripping and to enhance the extraction rate. As results, it was confirmed that the Np was mainly the pentavalent oxidation state in the low nitric acid solution. The extraction yield of Np was increased with increasing the concentration of DEHPA and $H_2O_2$ and decreased more rapidly with the increase of $HNO_3$ concentration. It was also found that the Np could be extracted into DEHPA even without the addiction any redox agents, although the extraction yield is rather low as about 70%. The extraction rate was proportional to the 0.516 power of $H_2O_2$ concentration and inversely proportional to 0.483 power of $HNO_3$ concentration as follows. $d[Np(V)]/dt=-1.391{\times}10^{-2}[H_2O_2]^{0.516}[HNO_3]^{-0.483}[Np(V)]$ Regardless of the $H_2O_2$, the Np extracted in the organic phase was effectively stripped to the aqueous phase with $H_2C_2O_4$. The Np could be stripped more than 92 % with 0.5M $H_2C_2O_4$.

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Electrochemical Analysis and Applications of Tetracycline Transfer Reaction Process at Liquid/liquid Interfaces (액체/액체 계면에서 테트라사이클린 전이반응의 전기화학적 분석 및 응용)

  • Liu, XiaoYun;Han, Hye Youn;Goh, Eunseo;Lee, Hye Jin
    • Applied Chemistry for Engineering
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    • v.28 no.5
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    • pp.506-512
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    • 2017
  • The transfer reaction characteristics of tetracycline (TC) across a polarized water/1,2-dichloroethane (1,2-DCE) interface was studied via controlling both pH and ionic strength of the aqueous phase in conjunction with cyclic and differential pulse voltammetries. Formal transfer potential values of differently charged TC ionic species at the water/1,2-DCE interface were measured as a function of pH values of the aqueous solution, which led to establishing an ionic partition diagram for TC. As a result, we could identify which TC ionic species are more dominant in the aqueous or organic phase. Thermodynamic properties including the formal transfer potential, partition coefficient and Gibbs transfer energy of TC ionic species at the water/1,2-DCE interface were also estimated. In order to construct an electrochemical sensor for TC, a single microhole supported water/polyvinylchloride-2-nitrophenyloctylether (PVC-NPOE) gel interface was fabricated. A well-defined voltammetric response associated with the TC ion transfer process was achieved at pH 4.0 similar to that of using the water/1,2-DCE interface. Also the measured current increased proportionally with respect to the TC concentration. A $5{\mu}M$ of TC in pH 4.0 buffer solution with a dynamic range from $5{\mu}M$ to $30{\mu}M$ TC concentration could be analyzed when using differential pulse stripping voltammetry.

Lower the Detection Limits of Accelerator Mass Spectrometry

  • John A., Eliades;Song, Jong-Han;Kim, Jun-Gon;Kim, Jae-Yeol;O, Jong-Ju;Kim, Jong-Chan
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.02a
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    • pp.243-244
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    • 2013
  • Over the past 15 years, several groups have incorporated radio-frequency quadrupole (RFQ) based instruments before the accelerator in accelerator mass spectrometry (AMS) systems for ion-gas interactions at low kinetic energy (<40 eV). Most AMS systems arebased on a tandem accelerator, which requires negative ions at injection. Typically, AMS sensitivity abundance ratios for radioactive-to-stable isotope are limited to Xr/Xs >10^-15, and the range of isotopes that can be analyzed is limited because of theneed to produce rather large negative ion beams and the presence of atomic isobaric interferences after stripping. The potential of using low-kinetic energy ion-gas interactions for isobar suppression before the accelerator has been demonstrated for several negative ion isobar systems with a prototype RFQ system incorporated into the AMS system at IsoTrace Laboratory, Canada (Ontario, Toronto). Requisite for any such RFQ system applied to very rare isotope analysis is large transmission of the analyte ion. This requires proper phase-space matching between the RFQ acceptance and the ion beam phase space (e.g. 35 keV, ${\varphi}3mm$, +-35 mrad), and the ability to control the average ion energy during interactions with the gas. A segmented RFQ instrument is currently being designed at Korea Institute for Science and Technology (한국과학기술연구원, KIST). It will consist of: a) an initial static voltage electrode deceleration region, to lower the ion energy from 35 keV down to <40 eV at injection into the first RFQ segment; b) the segmented quadrupole ion-gas interaction region; c) a static voltage electrode re-acceleration region for ion injection into a tandem accelerator. Design considerations and modeling will be discussed. This system should greatly lower the detection limits of the 6 MV AMS system currently being commissioned at KIST. As an example, current detection sensitivity of 41Ca/Ca is limited to the order of 10^-15 while the 41Ca/Ca abundance in modern samples is typically 41Ca/Ca~10^-14 - 10^-15. The major atomic isobaric interference in AMS is 41K. Proof-of-principal work at IsoTrace Lab. has demonstrated that a properly designed system can achieve a relative suppression of KF3-/41CaF3- >4 orders of magnitude while maintaining very high transmission of the 41CaF3- ion. This would lower the 41Ca detection limits of the KIST AMS system to at least 41Ca/Ca~10^-19. As Ca is found in bones and shells, this would potentially allow direct dating of valuable anthropological archives and archives relevant to our understanding of the most pronounced climate change events over the past million years that cannot be directly dated with the presently accessible isotopes.

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High Alloying Degree of Carbon Supported Pt-Ru Alloy Nanoparticles Applying Anhydrous Ethanol as a Solvent

  • Choi, Kwang-Hyun;Lee, Kug-Seung;Jeon, Tae-Yeol;Park, Hee-Young;Jung, Nam-Gee;Chung, Young-Hoon;Sung, Yung-Eun
    • Journal of Electrochemical Science and Technology
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    • v.1 no.1
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    • pp.19-24
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    • 2010
  • Alloying degree is an important structural factor of PtRu catalysts for direct methanol fuel cells (DMFC). In this work, carbon supported PtRu catalysts were synthesized by reduction method using anhydrous ethanol as a solvent and $NaBH_4$ as a reducing agent. Using anhydrous ethanol as a solvent resulted in high alloying degree and good dispersion. The morphological structure and crystallanity of synthesized catalysts were characterized by X-ray diffraction (XRD), high resolution transmission electron microscope (HR-TEM). CO stripping and methanol oxidation reaction were measured. Due to high alloying degree catalyst prepared in anhydrous ethanol, exhibited low onset potential for methanol oxidation and negative peak shift of CO oxidation than commercial sample. Consequently, samples, applying ethanol as a solvent, exhibited not only enhanced CO oxidation, but also increased methanol oxidation reaction (MOR) activity compared with commercial PtRu/C (40 wt%, E-tek) and 40 wt% PtRu/C prepared in water solution.

The effects of Two Terpenoids, UA and ONA on Skin Barrier and Its Application

  • S. W. Lim;S. W. Jung;Kim, Bora;H. C. Ryoo;Lee, S. H.;S. K. Ahn
    • Proceedings of the SCSK Conference
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    • 2003.09b
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    • pp.108-109
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    • 2003
  • Ursolic acid (UA) and Oleanolic acid (ONA), known as urson, micromerol, prunol and malol, are pentacyclic triterpenoid compounds which naturally occur in a large number of vegetarian foods, medicinal herbs, and plants. They may occur in their free acid form or as aglycones for triterpenoid saponins, which are comprised of a triterpenoid aglycone, linked to one or more sugar moieties. Therefore UA and ON A are similar in pharmacological activity. Lately scientific research, which led to the identification of UA and ONA, revealed that several pharmacological effects, such as antitumor, hepatoprotective, anti-inflammatory, antimicrobial, and anti-hyperlipidemic could be attributed to UA and ONA. Here, we introduced the effects of UA and ONA on acute barrier disruption and normal epidermal permeability barrier function. To clarify the effects of UA and ONA on skin barrier recovery, both flank skin of 8-12 weeks hairless mice were topically treated with samples (2mg/ml) after tape stripping, then measured recovery rate using TEWL on hairless mice. The recovery rate increased in UA and ONA treated groups at 6h more than 20% compared to vehicle treated group (p <0.05). For verifying the effects of UA and ONA on normal epidermal barrier, hydration and TEWL were measured for 1 and 3 weeks after UA and ONA applications (2mg/ml per day). We also investigated the features of epidermis and dermis using electron microscopy (EM) and light microscopy (LM). Both samples increased hydration compared to Vehicle group from 1 week without TEWL alteration (p<0.005). EM examination using Ru04 and OsO4 fixation revealed that secretion and numbers of lamellar bodies and complete formation of lipid bilayers were most prominent (ONA$\geq$UA>Vehicle). LM finding showed that stratum corneum was slightly increased and especially epidermal thickening and flattening was observed (UA>ONA>Vehicle). Using Masson-trichrome and elastic fiber staining, we observed collagen thickening and elastic fiber increasing by UA and ONA treatments. In vitro results of collagen and elastin synthesis and elastase inhibitory experiments were also confirmed in vivo findings. This result suggested that the effects of UA and ONA related to not only skin barrier but also collagen and elastic fibers. Taken together, UA and ONA can be relevant candidates to improve barrier function and pertinent agents for cosmetic applications.

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LATEST RESULTS OF THE MAXI MISSION

  • MIHARA, TATEHIRO
    • Publications of The Korean Astronomical Society
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    • v.30 no.2
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    • pp.559-563
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    • 2015
  • Monitor of All-sky X-ray Image (MAXI) is a Japanese X-ray all-sky surveyer mounted on the International Space Station (ISS). It has been scanning the whole sky since 2009 during every 92-minute ISS rotation. X-ray transients are quickly found by the real-time nova-search program. As a result, MAXI has issued 133 Astronomer's Telegrams and 44 Gamma-ray burst Coordinated Networks so far. MAXI has discovered six new black holes (BH) in 4.5 years. Long-term behaviors of the MAXI BHs can be classified into two types by their outbursts; a fast-rise exponential-decay type and a fast-rise flat-top one. The slit camera is suitable for accumulating data over a long time. MAXI issued a 37-month catalog containing 500 sources above a ~0.6 mCrab detection limit at 4-10 keV in the region ${\mid}{b}{\mid}$ > $10^{\circ}$. The SSC instrument utilizing an X-ray CCD has detected diffuse soft X-rays extending over a large solid angle, such as the Cygnus super bubble. MAXI/SSC has also detcted a Ne emission line from the rapid soft X-ray nova MAXI J0158-744. The overall shapes of outbursts in Be X-ray binaries (BeXRB) are precisely observed with MAXI/GSC. BeXRB have two kinds of outbursts, a normal outburst and a giant one. The peak dates of the subsequent giant outbursts of A0535+26 repeated with a different period than the orbital one. The Be stellar disk is considered to either have a precession motion or a distorted shape. The long-term behaviors of low-mass X-ray binaries (LMXB) containing weakly magnetized neutron stars are investigated. Transient LMXBs (Aql X-1 and 4U 1608-52) repeated outbursts every 200-1000 days, which is understood by the limit-cycle of hydrogen ionization states in the outer accretion disk. A third state (very dim state) in Aql X-1 and 4U 1608-52 was interpreted as the propeller effect in the unified picture of LMXB. Cir X-1 is a peculiar source in the sense that its long-term behavior is not like typical LMXBs. The luminosity sometimes decreases suddenly at periastron. It might be explained by the stripping of the outer accretion disk by a clumpy stellar wind. MAXI observed 64 large flares from 22 active stars (RS CVns, dMe stars, Argol types, young stellar objects) over 4 years. The total energies are $10^{34}-10^{36}$ erg $s^{-1}$. Since MAXI can measure the spectrum (temperature and emission measure), we can estimate the size of the plasma and the magnetic fields. The size sometimes exceeds the size of the star. The magnetic field is in the range of 10-100 gauss, which is a typical value for solar flares.