• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.15 no.4 s.97
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• pp.395-403
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• 2005

The dynamic characteristics of delaminated smart composite laminates are studied using animproved layerwise laminate theory. The theory is capable of capturing interlaminar shear stresses that are critical to delamination. The presence of discrete delamination is modeled through the use of Heaviside unit step functions. Stress free boundary conditions are enforced at all free surfaces. Continuity in displacement field and transverse shear stresses are enforced at each ply level. In modeling piezoelectric composite plates, a coupled piezoelectric-mechanical formulation is used in the development of the constitutive equations. Numerical analysis is conducted to investigate the effect of nonlinearity in the transient vibration of bimodular behavior caused by the contact impact of delaminated interfaces. Composite plates with delamination, subject to external loads and voltage history from surface bonded sensors, are investigated and the results are compared with corresponding experimental results and plates without delamination.

• Structural Engineering and Mechanics
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• v.53 no.6
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• pp.1167-1182
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• 2015

In this study, the stresses and electric potential redistributions of a cylinder made from functionally graded piezoelectric material (FGPM) are investigated. All the mechanical, thermal and piezoelectric properties are modeled as power-law distribution of volume fraction. Using the coupled electro-thermo-mechanical relations, strain-displacement relations, Maxwell and equilibrium equations are obtained including the time dependent creep strains. Creep strains are time, temperature and stress dependent, the closed form solution cannot be found for this constitutive differential equation. A semi-analytical method in conjunction with the Mendelson method of successive approximation is therefore proposed for this analysis. Similar to the radial stress histories, electric potentials increase with time, because the latter is induced by the former during creep deformation of the cylinder, justifying industrial application of such a material as efficient actuators and sensors.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2004.11a
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• pp.469-475
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• 2004

The transient analysis of delaminated smart composite laminates is studied using an improved layerwise laminate theory. The theory is capable of capturing interlaminar shear stresses that are critical to delamination. The presence of discrete delamination is modeled through the use of Heaviside unit step functions. Stress free boundary conditions are enforced at all fee surfaces. Continuity in displacement field and transverse shear stresses are enforced at each ply level. In modeling piezoelectric composite plates, a coupled piezoelectric-mechanical formulation is used in the development of the constitutive equations. Numerical analysis is conducted to investigate the effect of nonlinearity in the transient vibration of bimodular behavior caused by the contact impact of delaminated interfaces. Composite plates with delamination, subject to external loads and voltage history from surface bonded sensors, are investigated and the results are compared with corresponding experimental results and plates without delamination.

• Journal of Life Science
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• v.22 no.2
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• pp.281-284
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• 2012

This study demonstrated that upregulation of gene expression of endoplasmic reticulum (ER) stress chaperones (Bip, ERp29, calnexin, and PDI), ER stress sensors (PERK, ATF6, and Ire1), and cAMP phosphodiesterase 7A1 (cAMP PDE7A1) was induced by ER stresses in FRTL5 cells. While removing A23187 from the culture medium restored upregulation of cAMP PDE7A1 gene expression, removal of thapsigargin did not recover its expression. In addition, cAMP PDE7A1 gene expression was strongly inhibited by treatment with A23187 combined with thyroid stimulating hormone (TSH). The results are the first to show that ER stress induces cAMP PDE7A1 gene expression.

• Korean Journal of Agricultural Science
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• v.49 no.2
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• pp.269-284
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• 2022

The development of radish collectors has the potential to increase radish yields while decreasing the time and dependence on human labor in a variety of field activities. Stress and fatigue analyses are essential to ensure the optimal design and machine life of any agricultural machinery. The objectives of this research were to analyze the stress and fatigue of major components of a tractor-mounted radish collector under dynamic load conditions in an effort to increase the design dependability and dimensions of the materials. An experiment was conducted to measure the shaft torque of stem-cutting and transferring conveyor motors using rotary torque sensors at different tractor ground speeds with and without a load. The Smith-Watson-Topper mean stress equation and the rain-flow counting technique were utilized to determine the required shear stress with the distribution of the fatigue life cycle. The severity of the operation was assessed using Miner's theory. All running conditions produced more than 10⁷ of high cycle fatigue strength. Furthermore, the highest severity levels for motor shafts used for stem cutting and transferring and for transportation joints and cutting blades were 2.20, 4.24, 2.07, and 1.07, and 1.97, 3.81, 1.73, and 1.07, respectively, with and without a load condition, except for 5.24 for a winch motor shaft under a load. The stress and fatigue analysis presented in this study can aid in the selection of the most appropriate design parameters and material sizes for the successful construction of a tractor-mounted radish collector, which is currently under development.

• Molecules and Cells
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• v.47 no.1
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• pp.100001.1-100001.8
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• 2024

In eukaryotes, a primary protein quality control (PQC) process involves the destruction of conformationally misfolded proteins through the ubiquitin-proteasome system. Because approximately one-third of eukaryotic proteomes fold and assemble within the endoplasmic reticulum (ER) before being sent to their destinations, the ER plays a crucial role in PQC. The specific functions and biochemical roles of several E3 ubiquitin ligases involved in ER-associated degradation in mammals, on the other hand, are mainly unknown. We identified 2 E3 ligases, ubiquitin protein ligase E3 component N-recognin 1 (UBR1) and ubiquitin protein ligase E3 component N-recognin 2 (UBR2), which are the key N-recognins in the N-degron pathway and participate in the ER stress response in mammalian cells by modulating their stability. Cells lacking UBR1 and UBR2 are hypersensitive to ER stress-induced apoptosis. Under normal circumstances, these proteins are polyubiquitinated through Lys48-specific linkages and are then degraded by the 26S proteasome. In contrast, when cells are subjected to ER stress, UBR1 and UBR2 exhibit greater stability, potentially as a cellular adaptive response to stressful conditions. Although the precise mechanisms underlying these findings require further investigation, our findings show that cytoplasmic UBR1 and UBR2 have anti-ER stress activities and contribute to global PQC in mammals. These data also reveal an additional level of complexity within the mammalian ER-associated degradation system, implicating potential involvement of the N-degron pathway.

• Journal of Sensor Science and Technology
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• v.17 no.4
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• pp.267-272
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• 2008

Energy harvesting from the vibration through the piezoelectric effect has been studied for powering the small wireless sensor nodes. As piezoelectric uni-morph cantilever structure can transfer low vibration to large displacement, this structure was commonly deployed to harvest electric energy from vibrations. Through our previous results, when stress was applied on the cantilever, stress was concentrated on the certain point of the ceramic of the cantilever. In this study, for miniaturing the energy harvester, we investigated how the size of ceramics and the stress distribution in ceramic affects energy harvester characteristics. Even though the area of ceramic was 28.6 % decreased from $10{\times}35{\times}0.5mm^3$ to $10{\times}25{\times}0.5mm^3$, both samples showed almost same maximum power of 0.45 mW and the electro-mechanical coupling factor ($K_{31}$) of 14 % as well. This result indicated that should be preferentially considered to generate high power with small size energy harvester.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2017.05a
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• pp.240-244
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• 2017

Experimental verification in the rig test stage for component development is a vital link between the aeromechanical design and structural integrity validation process. Based on this premise, Non-Intrusive Stress Measuring System was adopted on the axial compressor test rig to measure the static and dynamic tip deflection of all blades by using tip-timing sensors. Through analyzing vibration characteristics, we evaluated the vibratory stresses seen on the blades fatigue critical location; detected synchronous resonances which are the source of High Cycle Fatigue (HCF) in blades; presented non-synchronous vibration response by aerodynamic excitation and individual blade mis-tuning patterns.

• Journal of Sensor Science and Technology
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• v.28 no.5
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• pp.329-333
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• 2019

Solution-processed oxide thin-film transistors (TFTs) have garnered great attention, owing to their many advantages, such as low-cost, large area available for fabrication, mechanical flexibility, and optical transparency. Negative bias stress (NBS)-induced instability of sol-gel IGZO TFTs is one of the biggest concerns arising in practical applications. Thus, understanding the bias stress effect on the electrical properties of sol-gel IGZO TFTs and proposing an effective recovery method for negative bias stressed TFTs is required. In this study, we investigated the variation of transfer characteristics and the corresponding electrical parameters of sol-gel IGZO TFTs caused by NBS and positive bias recovery (PBR). Furthermore, we proposed an effective PBR method for the recovery of negative bias stressed sol-gel IGZO TFTs. The threshold voltage and field-effect mobility were affected by NBS and PBR, while current on/off ratio and sub-threshold swing were not significantly affected. The transfer characteristic of negative bias stressed IGZO TFTs increased in the positive direction after applying PBR with a negative drain voltage, compared to PBR with a positive drain voltage or a drain voltage of 0 V. These results are expected to contribute to the reduction of recovery time of negative bias stressed sol-gel IGZO TFTs.

• Wind and Structures
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• v.32 no.1
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• pp.31-46
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• 2021

The current research deals with, stability/instability and cylindrical composite nano-scaled shell's resonance frequency filled by graphene nanoplatelets (GPLs) under various thermal conditions (linear and nonlinear thermal loadings). The piece-wise GPL-reinforced composites' material properties change through the orientation of cylindrical nano-sized shell's thickness as the temperature changes. Moreover, in order to model all layers' efficient material properties, nanomechanical model of Halpin-Tsai has been applied. A functionally modified couple stress model (FMCS) has been employed to simulate GPLRC nano-sized shell's size dependency. It is firstly investigated that reaching the relative frequency's percentage to 30% would lead to thermal buckling. The current study's originality is in considering the multifarious influences of GPLRC and thermal loading along with FMCS on GPLRC nano-scaled shell's resonance frequencies, relative frequency, dynamic deflection, and thermal buckling. Furthermore, Hamilton's principle is applied to achieve boundary conditions (BCs) and governing motion equations, while the mentioned equations are solved using an analytical approach. The outcomes reveal that a range of distributions in temperature and other mechanical and configurational characteristics have an essential contribution in GPLRC cylindrical nano-scaled shell's relative frequency change, resonance frequency, stability/instability, and dynamic deflection. The current study's outcomes are practical assumptions for materials science designing, nano-mechanical, and micromechanical systems such as micro-sized sensors and actuators.