• Journal of Life Science
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• v.23 no.12
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• pp.1428-1435
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• 2013

The aim of this study is to investigate the melanogenic effect of Oenanthe javanica ethanolic extracts (OJE) containing quercetin and kaempferol in melanoma cells (B16F1). In order to determine whether OJE inhibits melanin synthesis at the cellular level, the melanoma cells were cultured in the presence of different concentrations of OJE. In the present study, the antioxidant effects of OJE on DPPH radical scavenging, power reduction, lipid peroxidation, and DNA oxidation were evaluated in a cell free system. Furthermore, the effect of OJE on the production of melanin was determined by dopaquinone (DOPA) assay and tyrosinase activity. In addition, the protein expression of tyrosinase, as well as antioxidant enzymes such as superoxide dismutase (SOD)-1, SOD-2 and glutathione reductase (GSH), were examined using Western blot analysis. In this study, it was observed that OJE exhibited an inhibitory effect on lipid peroxidation and blocked the DNA oxidation induced by the hydroxyl radical produced by Fenton's reagent. OJE increased melanin synthesis above 50 ${\mu}g/ml$ and tyrosinase activity was detected above 50 ${\mu}g/ml$. In Western blot analysis, OJE increased the expression levels of tyrosinase, SOD-1, SOD-2, and GSH in a dose-dependent manner. These findings indicate that OJE with antioxidant activity can regulate the tyrosinase activity and melanin production in melanocyte, suggesting that it could promote the development of black hair as well as protect skin from oxidative stress.

• Korean Journal of Materials Research
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• v.10 no.4
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• pp.312-316
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• 2000

A study has been made to investigate the effects of hot isostatic pressing(HIP ping) on bond strength and elevated temperature characteristics of thermal barrier coating(TBC). The specimens were prepared by HIPping of TBC which is composed of the ceramic top coat(8wt%$Y_2$$O_3$-$ZrO_2$) and the metallic bond coat on the matrix of IN738LC superalloy. The results showed that the porosity and microcracks in the ceramic top coat of TBC were significantly decreased by HIP. As a result, the bond strength of the HIPped coating was increased above 48% compared to that of as-coated specimen and microstructure was homogenized. It was found that the thermal cycle resistance of HIPped coating was inferior to that of as-coated specimen. It was considered that this result was mainly caused by the reduction of internal defects in the top coat layer which could play a role in relaxing the thermal stress due to a large difference in thermal expansion between TBC and matrix.

• The Korean Journal of Ecology
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• v.26 no.3
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• pp.135-142
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• 2003

Four legume plants showed better growth by the external nitrogen supply rather than the symbiotic nitrogen fixation only under salt additions. In case of Glycine max and Phaseolus angularis, total nitrogen contents decreased by high salinity level but their amino acid levels significantly increased with the increase of salt treatments and indicated high soluble-/insoluble-N ratios. Cassia tora and Albizzia julibrissin contained less amino acids than G. max and P. angularis but total N (esp. insoluble N fraction) increased with higher salt levels. Asparagine occurred as a main amino acid especially in G. max and P. angularis and can be seen as potential N-storage form in these plants. It might be play an important role for the osmoregulation mechanism under the saline condition. Meanwhile, to investigate what kinds of nitrogen sources are effective for overcoming salt stress on soybean plants, various N forms and concentrations (NH₄NO₃-N, NO₃-N, NH₄NO₃-N; 2.5 and 5 mM) were additionally supplied to the salt gradient medium. Soybean plants treated with NH₄NO₃-N showed the best growth up to 40 mM NaCl and NO₃- fed plants indicated good growth even at 80 mM NaCl treatments. Contrary to NH₄NO₃- and NO₃- fed plants, NH₄/sup +/- fed plants showed remarkable growth reduction and died by 40 and 80 mM NaCl treatments after the first harvest (15th day). Consequently, these results suggest that salt excluding and resistant capacities of soybean plants under NaCl treatments are increased in order of NH₄ - N, control, NO₃- N and NH₄NO₃- N depending on N concentration except NH₄- N treatments.

• Journal of the Korean Recycled Construction Resources Institute
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• v.5 no.1
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• pp.103-110
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• 2010

Recently, reducing usage of cement and using by-product of industry such as blast furnace slag and fly-ash have been increased to reduce $CO_2$ gas emission. That apply to construction. As a result, reduction of environmental stress and recycling of resources are expected. In this study, as basic study to the reuse of resources and reduce Environmental Load, comparing and analyzing hardening characteristics and durability as using the blast furnace slag and fly-ash, examining concrete characteristics substituted the three elements for the blast furnace slag and fly-ash and evaluating the relationship as binder. Through this, it want to provide the basic data for mass utilization. Blast furnace slag powder and replaced at fly-ash compressive strength of concrete in the strength of the initial seven days material age lower level of expression significantly compared to the concrete, but, 28 days after the similar or higher compressive strength than the concrete expression of the was. In addition, the reserves replacement of blast furnace slag powder salt injury increasing resistance are seen improvements, according to the conventional blast furnace slag powder study by the chloride ions on the surface of the concrete are improved being fixation salt injury resistance is considered.

• Korean Journal of Construction Engineering and Management
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• v.16 no.6
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• pp.101-111
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• 2015

The modular construction method has been getting more attention followed by global eco-friendly trend as the domestic construction industry has focused more on remodeling and extension work. The modular construction method is an industrialized construction system which is not likely as the existing construction method it manufactures more than 70% modules at the factory then assembling can be completed in a short amount of time on site. The modular construction method has various strengths; shortening of construction period by on-site work decrease, weight pressure reduction by usage of light steel frames and cost saving by repetitive manufacturing. However, it is currently not expanded due to the existing commercialized construction method. Therefore, this research is in order to help the related authorities make decisions to select the construction method and motivate expansion of modular construction method which can be utilized effectively in the extension works. The intention of this research is to stress differentiation from other construction methods in construction period, construction expenses, labor and forces by comparing and analyzing actual cases, to inform competitiveness of modular construction method by concrete effect analysis and to support adoption of the modular construction method into the domestic industry.

• Journal of the Korean Society of Safety
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• v.28 no.1
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• pp.117-124
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• 2013

Emergency operating procedures(EOPs) of nuclear power plants should be described considering the cognitive capability and limitation of operators and provide appropriate information in the aspect of human factors. Procedures which doesn't consider cognitive characteristics of operators can become causes of human errors. In previous researches, in order to reduce these problems related to the description of EOP, an improvement suggestion for EOP writer's guide has been proposed, which is reflected human factors aspects that should be considered when describing EOPs. The proposed items, however, have a necessity to be validated because it was listed from various documents such as standards and guidelines without any special validation process. For that reason, in this study, a validation process were performed to show that procedures, which are described in compliance with the requirement items proposed in the improved EOP writer's guide, have positive effects in the aspects of human errors and performance comparing with previous procedures. Experiments were performed to compare the performances of two tasks which are described in compliance with each writer's guide of before and after the improvement During each task was performed in experiments, changes of physiological responses such as EEG and ECG were measured to evaluate the cognitive workload and the stress of operators in each task. And also, as the performance, frequencies of errors and cognition speeds of each task were evaluated. In the results of the experiment, the portions of the ${\beta}$ wave decreased in the tasks overall after the improvement. In the case of ECG, change rates of the mean of R-R interval were decreased in the tasks after improvement. In the results of the performance, the cognition and the response time of the tasks after the improvement were predominant with statistical significancies. Error times in the tasks after improvement were decreased or same to the tasks before improvement. Conclusively, it was validated that the procedures were described in compliance with the improved EOP writer's guide had effects on the reduction of human errors and improvement of performance.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.29 no.1
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• pp.30-34
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• 2016

In this paper, we report that selective etching on N-polar face by EC (electro-chemical)-etching effect on the reduction of bowing and strain of FS (free-standing)-GaN substrates. We applied the EC-etching to concave and convex type of FS-GaN substrates. After the EC-etching for FS-GaN, nano porous structure was formed on N-polar face of concave and convex type of FS-GaN. Consequently, the bowing in the convex type of FS-GaN substrate was decreased but the bowing in the concave type of FS-GaN substrate was increased. Furthermore, the FWHM (full width at half maximum) of (1 0 2) reflection for the convex type of FS-GaN was significantly decreased from 601 to 259 arcsec. In the case, we confirmed that the EC-etching method was very effective to reduce the bowing in the convex type of FS-GaN and the compressive stress in N-polar face of convex type of FS-GaN was fully released by Raman measurement.

• Journal of Sensor Science and Technology
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• v.8 no.3
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• pp.265-273
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• 1999

Various oxide films are commonly used as a sacrificial layer or etch mask in the fabrication of microelectromechanical systems (MEMS). Large residual strain of these oxide films causes the wafer to bow, which can have detrimental effects on photolithography and other ensuing processes. This paper investigates the residual strain of tetraethoxysilane (TEOS), low temperature oxide (LTO), 7 wt% and 10 wt% phosphosilicate glass (PSG). Euler beams and a bent-beam strain sensor are used to measure the residual strain. A poly silicon layer is used as the sacrificial layer, which is selectively etched away by $XeF_2$. First, the residual strain of as-deposited films is measured, which is quite large. The residual strain of the films is also measured after annealing them not only at $500^{\circ}C$, $600^{\circ}C$, $700^{\circ}$ and $800^{\circ}C$ in $N_2$ environment for 1 hour but also at the conditions for depositing a $2\;{\mu}m$ thick polysilicon at $585^{\circ}C$ and $625^{\circ}C$. Our results show that the 7 wt% PSG is best suited as the sacrificial layer for $2\;{\mu}$ thick polysilicon processes.

• Journal of the Korean Geosynthetics Society
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• v.13 no.4
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• pp.33-43
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• 2014

Recently, the case to construct the structure on the soft clayey ground has increased and in order to the reduction of the cost of construction and maintenance on the social infrastructure facilities we have been trying to improve the soft clayey ground using the existing methods such as the pre-loading method and the vertical drain method. Like this, when various ground improvement methods are applied on the soft clayey ground, a long-term consolidation settlement will be key issue due to low permeability coefficient of cohesive soil. According to existing research results that relate to the consolidation settlement, the loading periods for existing the standard consolidation test (Oedometer test) to obtain the consolidation parameters are needed for minimum ten days or more. Therefore, in this study, the standard consolidation test (24 hours step-loading) and constant strain rate consolidation test changed by strain rate was performed using the remolded marine clay on Gwangyang bay composed of a soft clayey ground of the south-west coast. From the laboratory test results, the characteristics of compression, strain-effective stress relations by constant strain rate and the variation characteristic of the pore water pressure by different of loading speed and the relation between consolidation parameters and constant strain rate are compared and analyzed.

• Journal of Korean Society of Steel Construction
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• v.20 no.1
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• pp.105-119
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• 2008

In steel deck bridges suffering directly on wheel load according to the number of serviced years, the occurrence of fatigue cracks increases in structural details, which includes the cross section parts of the longitudinal rib and transversal rib, and so on. Through the control method for these fatigue cracks the increased thickness of the steel deck plate or the application of retrofit detail to the inside of the longitudinal rib was observed to be effective. This study suggests structural details for the retrofitted and non-retrofitted longitudinal rib. The target details in this study are the connection parts of the lo ngitudinal and transversal rib, and the slit parts of transverse rib where fatigue cracks were frequently reported in previous studies. In the analyses, detailed structural analyses were performed as parameters, which include the shape, change of size and attached position. From the results the stress reduction in the target details was observed to be larger in the retroffited details. Also, the improvement of fatigue strength is more effective in the retrofitted details with the vertical rib than the bulkhead plate.