• 대한한의학방제학회지
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• 제25권2호
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• pp.223-251
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• 2017

Objectives : A lot of experiment results of Yugmijihwangtang(YM) are reported in various kinds of journals. Many of them report on the new effects that are not recorded in the traditional medical texts. So it is necessary to take it into consideration that newly reported effects could be of help to clinical practice, because this process of comparison of Donguibogam and scientific experiment results will have basis to lead into the evidence based medicine. Methods : We compared the effects of in Donguibogam and the experiment results of YM. Results : The effects of YM in Donguibogam are to replenish essence and marrow, and to treat red wen, fatigue, treat hypouresis, urinary sediment, urinary urgency, hematuria, hydrocephalus, speech and movement retardation, yin-deficiency, diabetes mellitus, nonalcoholic fatty liver, melanoma, disability to see near and far sight, tinnitus, hearing loss, alopecia, angiogenesis, cough, cough at night, trachyphonia, and, infantile convulsion. The experiment results of YM since 2000 in both Korea and China are to inhibit atopic dermatitis, renal interstitial fibrosis, anti-oxidant, emphysema, stress, glomerulosclerosis, diabetic nephropathy, chronic glomerulonephritis, hemorrhage, plantar sweating, dermal aging, kidney aging, bone loss, breast cancer, pathological myocardial cell, primary liver cancer, thrombosis, osteoporosis, intrauterine growth retardation, chronic renal failure, IgA nepropathy, slow cerebral development, and hippocampal tissue lesions on the one hand, and to help bone formation, renin-angiotensin- aldosterone system, cerebral recovery, cognitive function and expression, osteoblast proliferation and differentiation, learning and memory, cold-tolerance and oxygen deficit-tolerance and anti-fatigue, endometrial formation, humoral and cell-mediated immunity, immune regulation effect, Hypothalamus-Pituitary-Ovary Axis, and spermatogenesis, on the other hand. Conclusion : When we compared the effects of YM with the experiment results of YM, there existed a considerable gap between them. So, from now on, it is expected that a great effort and consideration are needed to solve these gaps from an academic and clinical point of view.

• 한국안광학회지
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• 제17권2호
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• pp.171-176
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• 2012

목적: 본 연구는 스마트폰과 모니터 영상을 짧은 기간 동안 시청한 이후 근거리 사위와 폭주근점의 변화를 비교하였다. 방법: 20~30대(평균나이 $21.84{\pm}5.14$세)의 안질환이 없고 건강한 눈을 가진 50명을 실험 대상자로 하였다. 시청 시간은 5~20분으로, 회복 시간은 10분으로 구성하였다. 근거리 사위와 폭주근점은 스마트폰과 모니터의 시청 전후로 검사하였고, 시각적 피로도에 의한 자각증상은 영상 시청 전후 설문지로 조사하였다. 결과: 스마트폰 영상시청에서 나타난 외사위 경향은 모니터보다 큰 것으로 나타났고, 이러한 외사위의 변화는 10분 후 회복하였다. 스마트폰 시청 이후 나타난 폭주근점은 모니터에서보다 멀어지는 경향을 보였으며, 스마트폰은 모니터보다 더 많은 시각적 피로를 유발하였다. 결론: 지속적인 스마트폰의 작업은 사위 및 폭주근점의 변화를 초래하였고, 이러한 유형의 스트레스로 시각적 피로를 초래할 수 있다. 그러므로 적절한 휴식은 시각적 피로의 회복에 도움을 줄 수 있을 것으로 사료된다.

• 한국패션뷰티학회지
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• 제3권3호
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• pp.48-55
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• 2005

The summary of a study of efficacy of Rose essential oil and Lavender essential oil against physiologic active change s of skin caused to surfactant is as follows. 1. In feed intake efficiency, there is more significant difference than control group, and then in water intake, there are significant differences between each group. It is presented that the water intake efficiency ratio of the group treated by Rose essential oil and Lavender essential oil is higher than all of groups to be participated in experiment. And then, the reason that the group treated Lavender essential oil is lower than any other group is needed water intake to be caused by stress. 2. As the result of serum analysis, in atherosclerotic index(A.I), the cholesterol of control group is higher than that of the group treated. As HDL cholesterol is activated, the dan1aged group is higher than control group, in LDL cholesterol the control group is higher. It is seen that the damaged group of the quantity of HDL cholesterol is lower frequently in A.I. This fact is presented that HDL cholesterol that cholesterol is exhausted is changed, because of the dan1aged group that replacement is activated. 3. As the observed result of alteration of sebaceous glands, it is appeared that the demage of sebaceous glands is destroyed in the damaged group. It is observed that epidermis of the group applied by Rose essential oil after treated surfactant is dry, secretion of phenomenon of water and sebum is appeared more. It is observed that the epidermis recovery of the group applied by Lavender essential oil after treated surfactant is insufficient. And then it is seen that stratum corneum is recovered and the quantity of sebum secretion is decreased. 4. As the observed result of alteration of Mast cell group treated by Rose essential oil and Lavender essential oil for 3 weeks Luna's stain(${\times}100$), it is observed that the damaged group treated by Lavender essential oil is numerous in alteration of mast cell's number and Mast cell's size is larger than the dan1aged group. It is presented that the Mast cell's number and Mast cell's size is larger than the damaged group, the Mast cell's size and quantity of the group treated by Rose essential oil and Lavender essential oil is decreased more.

• 수면정신생리
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• 제9권1호
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• pp.61-67
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• 2002

본 연구는 정상인을 대상으로 바이오피드백 시스템으로 측정된 정신생리적 반응의 특징을 파악하는 것을 목적으로 시행되었다. 연구 결과 20대에서 피부전도반응이 다른 연령대에 비해 유의하게 높았으며, 여성에서 전두부 근전도가 남성에 비해 유의하게 높았다. 한편 정상인에서 바이오피드백 측정치와 자가 평가한 기분 변수와는 관련이 없는 것으로 나타났다. 본 연구의 결과는 향후 바이오피드백 시스템 기기를 이용하여 평가를 할 때 성별, 연령별 특징을 고려해야 함을 시사한다. 본 연구에서 제시된 정신생리변수에 관한 중요한 특징들은 향후 동종의 바이오피드백 시스템을 이용한 연구결과를 비교하는 데 도움이 될 것으로 기대된다.

• 대한치과보철학회지
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• 제58권2호
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• pp.161-168
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• 2020

임플란트 고정성 보철물의 실패는 과도한 교합스트레스와 같은 생역학적인 요인과 세균 감염, 염증과 같은 생물학적인 요인으로 인하여 일어난다. 임플란트 합병증으로 인한 문제가 해결되지 않고 악화되어 심한 골흡수가 일어난 임플란트는 제거되어야 하며, 제거 후 잔존 치아와 잔존 임플란트 및 잔존 치조제를 고려하여 새로운 치료를 계획해야 한다. 본 증례의 환자는 하악 무치악부에 약 10년 전 식립한 하악 고정성 임플란트 보철물 중 일부를 임플란트 주위염으로 인하여 제거하게 되었다. 추가 임플란트 재식립을 위한 잔존 치조골의 상태를 재평가 하고 소수의 임플란트를 추가 식립 후 임플란트 서베이드 크라운을 지대치로 하는 임플란트 융합 가철성 국소의치로 최종 치료하였다. 이를 통해 실패 이후 저작기능을 다시 회복하고 구강위생 관리에 유리한 조건으로 전환하였기에 이를 보고하고자 한다.

• 생명과학회지
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• 제25권11호
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• pp.1324-1330
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• 2015

운동에 종사하는 엘리트 운동선수나 동호인들은 지속적인 같은 동작의 반복, 잦은 경쟁스트레스의 경험, 그리고 신체적인 컨디션이 좋지 않은 상황에서의 과도한 훈련의 요구 때문에 근육, 건, 인대, 염좌 및 골절과 같은 부상을 비롯한 근골격계 질환을 야기한다. 그리고 과도한 오버리칭, 경쟁불안으로 인한 스트레스, 및 피로회복의 부족 등으로 운동기술의 정체를 비롯한 운동수행력의 감소는 물론 심리적인 스트레스와 면역반응의 감소를 경험하게 된다. 따라서 본 연구에서는 과훈련증후군의 원인과 증상 및 치료와 처치에 대해 분석하고 이러한 증후군과 면역반응과 연관성을 비교 및 분석하여 운동 동호인을 비롯한 운동 선수들에게 나타날 수 있는 면역력의 감소를 줄여, 운동수행력의 증진은 물론 건강유지와 면역력 회복을 도모하고자 한다. 본 연구의 목적을 달성하기 위해 본론에서는 과훈련 증후군에 대한 전반적인 내용을 실험연구를 비롯한 관련 연구논문을 중심으로 분석하였고, 아울러 과훈련 증후군과 면역반응 및 알레르기 면역반응과의 연관성에 대해 면밀한 분석을 실시하였다. 본 연구 결과를 토대로 많은 스포츠 현장에서 과훈련증후군에 관한 실험적인 연구와 면역반응 및 알레르기반응과의 연관성 분석을 토대로 한 실험적 연구가 진행되어야 할 것으로 여겨지며, 본 연구가 많은 운동선수들과 동호인들의 건강관리는 물론, 면역력의 증가를 도모하는 데에 도움을 줄 것으로 여겨진다.

• 한국환경과학회지
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• 제18권10호
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• pp.1135-1141
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• 2009

Carrots (Daucus carota L.) are consumed as an important dietary source of provitamin A including $\beta$-carotene, $\alpha$-carotene and lutein. An HPLC method was applied to determine the content of the carotenoid composition in carrot cutivars cultivated in Korea. HPLC analyses were carried out with five carrot cultivars (Socheon-5-chon, Hongsim-5-chon, Myeongju-5-chon, Seonhongbom-5-chon and Betarich) sown at April, 2007 and six cultivars (Yeoreum-5-chon, Hanyeoreum-5-chon, Sinheukjeon-5-chon, Bibariheukjeon, Manina and Betarich) sown at August of the same year. In general, the former varieties are not used for the sowing at summer because of their bolting (growth of floral axis). The former and the latter carrots were harvested after 110 and 96 days from seeding, respectively, and the carotenoids were extracted with acetone after freeze-drying. The amount of $\alpha$-carotene ($117.7{\sim}205.3\;{\mu}g/g{\cdot}DW$) was similar to that of $\beta$-carotene ($113.1{\sim}189.6\;{\mu}g/g{\cdot}DW$) for the carrot cultivars sown at spring, while the content ($46.2{\sim}71.1\;{\mu}g/g{\cdot}DW$) was about a half of $\beta$-carotene content ($92.5{\sim}140.2\;{\mu}g/g{\cdot}DW$) for the latter cultivars. In addition, the average content of lutein ($25.2\;{\mu}g/g{\cdot}DW$) in the former cultivars was eight times higher than that in the latter cultivars ($3.1\;{\mu}g/g{\cdot}DW$). Among the spring cultivation types, Socheon-5-chon and Myeongju-5-chon showed higher amount of $\alpha$-carotene and $\beta$-carotene, while the higher amount was determined in Yeoreum-5-chon and Sinheukjeon-5-chon among the autumn cultivation types. Validation of the HPLC-DAD method showed good linearity ($r^2$ > 0.997) of the three compounds analyzed in a wide concentration range ($0.025{\sim}20\;{\mu}g/ml$). The R.S.D. values for intra-day and inter-day precision were less than 19.2% and the mean recovery of each compound was 85.4~104.7%.

• Composites Research
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• 제29권3호
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• pp.117-124
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• 2016

본 연구에서는 스카프 패치로 수리한 복합재 단일겹침 체결부의 파손강도를 시험과 해석으로 연구하였다. 스카프 비, 모재의 적층패턴, 결함크기를 달리 하며 총 45개의 시편에 대한 시험을 수행하여 파손강도와 파손모드를 분석하였다. 다양한 형상의 시편에 대한 시험 결과, 한 경우를 제외하고는 수리 후의 체결부가 결함이 없는 체결부 강도 이상의 강도를 회복하며, 체결부 인자에 따른 특별한 차이는 나타나지 않는 것을 확인하였다. 파손강도가 낮게 나타난 한 경우에 대한 파손면 분석결과 모재의 표면층인 평직층의 표면처리가 충분치 않은 것이 원인인 것으로 판단되었다. 시험 결과의 분석을 위해 3차원 유한요소해석을 수행하였는데, 유한요소해석에서도 고려한 체결부 인자가 상하부 모재와 패치, 접착층에서의 응력에 큰 영향을 미치지 않는 것을 확인하였다. 이는 단일겹침 체결부의 경우 외부 인장하중이 겹침영역을 통과하면서 상하부 모재로 분산되기 때문인 것으로 판단된다. 시험과 해석 결과 모재 중앙에 결함이 존재하는 단일겹침 체결부의 경우 절차에 따라 패치 접착이 이루어지고, 모재의 표면처리가 충분히 이루어진다면 수리를 통해 손상 전 강도를 회복할 수 있는 것으로 판단된다.

• Korean Journal of Acupuncture
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• 제24권1호
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• pp.171-187
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• 2007

Objectives : This study was performed to determine if Orostachys japonicus A. Berger herbal acupuncture (OjB) provides the protective effect against the loss of cell viability and DNA damage induced by oxidant in renal proximal tubular cells. Methods : The cell viability was evaluated by a MTT reduction assay and DNA damage was estimated by measuring double stranded DNA breaks in opossum kidney (OK) cells, an established proximal tubular cell line. Lipid peroxidation was determined by measuring malondialdehyde (MDA), a product of lipid peroxidation. Results : H2O2 increased the loss of cell viability in a time-dependent manner, which were prevented by 0.1% OjB. The protective effect of OjB was dose-dependent over concentration range of 0.05-0.5%. H2O2 caused ATP depletion and DNA damage, which were prevented by OjB and the hydrogen peroxide scavenger catalase. The loss of cell viability by H2O2 was not affected by the antioxidant DPPD, but lipid peroxidation by the oxidant was completely inhibited by DPPD. Generation of superoxide and H2O2 in neutrophils activated by phorbol-12,13-dibutyrate was inhibited by OjB in a dose-dependent manner. OjB inhibited generation of H2O2 in OK cells treated with antimycin A and exerted a direct H2O2 scavenging effect. Exposure of OK cells to 1 mM tBHP caused a significant depletion of glutathione which was prevented by OjB. OjB accelerated the recovery in cells cultured for 20 hr in normal medium without oxidant following oxidative stress. Conclusions : These results suggest that OjB exerts the protective effect against oxidant-induced cell injury and its protective effect was resulted from radical scavenging and antioxidant activities.

• 동아시아식생활학회지
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• 제22권6호
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• pp.758-771
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• 2012

This research contains awareness of antioxidant and intakes of antioxidant foods for the present evaluate college students in Seoul, 375 patients were investigated. The subjects, the woman college student more than male's responded, showed a uniform distribution in the allowance, grade and the most type of residence is living apart from their family. All male and female college students recognize a lot about health, but male college students had higher than female students interested in the health, on the other hand, female college students had higher than male college students for the health efforts for the promotion of a healthy. Awareness about the oxide and active oxygen is moderate level, but knowledge about active oxygen is low level, they responded that active oxygen was caused when received stress or do strenuous exercise. General Health Functional Foods recognized that the usual intake, but intake of antioxidant was when the activity was caused by active oxygen. They recognized that the antioxidant effect is anti-aging and vitamin, wine and tea, were perceived as antioxidant foods, are popularly known. Usually, people was initially recognized through the internet in university or high school, they desire to obtain information was high but the effort to gain understanding and knowledge about antioxidant are relatively low. The result of comparing the difference of natural antioxidant foods and antioxidant healthy functional foods, recognizes of effects and absorption rate are similar, but recognizes that natural food intake is better recognition in the economics and health functional food is better recognition in the easy intake and nature foods was more preferred than functional foods because of nature friendly. Trying to intake of antioxidant foods is low, but people is expected anti-aging and fatigue recovery through the intake of antioxidant food. People think that intake is irrelevant to the season, but summer is higher than other seasons. Showed that efficacy perceptions about health supplements are higher, but efficacy perceptions about antioxidant health supplements when ingested are at a moderate level, which is lower, due to low antioxidant for understanding. Antioxidant functional health food intake will be affected the gifts or the people around them and purchase is also more influenced by surround people than themselves. So showed that most college students prefer natural antioxidant foods than antioxidant health supplements, in case of ingested antioxidant health supplements also showed that it was consumed by surround people than personal will.