• 소성∙가공
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• 제27권2호
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• pp.123-129
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• 2018

In the present study, the mechanical behavior of the spray-formed high speed steel was investigated employing the internal variable theory of inelastic deformation. Special attention was focused on the effect of the microstructure evolution during the hot working process, such as the distribution of carbides to provide a basic database for the production condition of high speed steels with excellent properties. The billets of high speed steel ASP30TM were fabricated by a spray forming, and the subsequently hot-rolled and heat-treated process to obtain uniformly distributed carbide structure. As noted the spray-formed high speed steel showed relatively coarser carbides than hot-rolled and heat-treated one with fine and uniformly distributed carbide structure. The step strain rate tests and high temperature tensile tests were carried out on both the spray-formed and the hot-rolled specimens, to elucidate their high temperature deformation behavior. The spray-formed high speed steel showed much higher flow stress and lower elongation than the hot-rolled and heat-treated steel. During the tensile test at $900^{\circ}C$, the interruption of the deformation for 100 seconds was conducted to reveal that the recovery was a main dynamic deformation mechanism of spray formed high speed steel. The internal variable theory of the inelastic deformation was used to analyze data from the step strain rate tests, revealing that the activation energies for hot deformation of as-spray-formed and hot-worked steels, which were 157.1 and 278.9 kJ/mol, and which were corresponding to the dislocation core and lattice diffusions of ${\gamma}-Fe$, respectively.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2009년도 제33회 추계학술대회논문집
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• pp.627-630
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• 2009

이젝터 시스템은 주유동 제트에 발생되는 전단 응력과 압력차에 의해 흡입 챔버 압력에 영향을 미치거나 이차 흡입 유동을 유도한다. 이젝터는 터빈 기반 복합사이클 추진기관 및 로켓엔진의 고고도 모사 설비, 압력회복장치, 담수화 시스템, 이젝터 램젯시스템과 같이 많은 분야에 적용되어 널리 사용된다. 본 연구에서는 아음속 및 음속 조건에서 작동하는 이젝터의 형상 및 운전 조건을 결정하는 설계 절차를 수립하고자 하였다. 또한, 이론적 방법과 시험적 연구를 통해 축소 확대 디퓨저가 장착된 이젝터의 작동 특성을 파악하였다. 결국, 수치해석을 통해 요구 성능을 만족하는 이젝터의 최적 형상을 결정하였으며 다양한 노즐 목 및 챔버 직경을 변화시킨 이젝터에 대한 성능 시험을 통해 계산 결과를 검증하였다.

• 동의생리병리학회지
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• 제34권2호
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• pp.81-87
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• 2020

Cognitive impairment is symptoms of dementia, a degenerative brain disease that is drawing attention in a rapidly aging society. This study was conducted to investigate the improvement of cognitive function of Leonurus japonicus on scopolamine-induced memory impairment in mice and the effect and mechanism of memory recovery. In vivo studies were conducted on mice orally pretreated with L. japonicus in doses of 50, 100 and 200 mg/kg (p.o.) and scopolamine (1 mg/kg, i.p.) were injected 30 min before the behavioral task. Antioxidant activity was assessed by 2,2-diphenyl-1-picryl hydrazyl (DPPH) assay and 2,2-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay, and acetylcholinesterase (AChE) inhibition activity evaluated by Ellman's method. In behavior studies showed that L. japonicus has an improved the memory of scopolamine-treated mice in Y-maze, passive avoidance and Morris water maze test. In addition, L. japonicus was also exerted free radical scavenging activity and inhibited acetyl cholinesterase activity. These results suggest that L. japonicus improves short-term and long-term memory in scopolamine-induced memory decline model and prevents scopolamine-induced memory impairments through in reduced oxidative stress and acetyl cholinesterase inhibition effect. Thus, L. japonicus is related to functional medicinal materials for prevention and treatment of human dementia patients.

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2007년도 추계학술대회 논문집
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• pp.156-160
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• 2007

Ejector system is a device to transport a low-pressure secondary flow by using a high-pressure primary flow. Ejector system is, in general, composed of a primary nozzle, a mixing section, a casing part for suction of secondary flow and a diffuser. It can induce the secondary flow or affect the secondary chamber pressure by both shear stress and pressure drop which are generated in the primary jet boundary. Ejector system is simple in construction and has no moving parts, so it can not only compress and transport a massive capacity of fluid without trouble, but also has little need for maintenance. Ejectors are widely used in a range of applications such as a turbine-based combined-cycle propulsion system and a high altitude test facility for rocket engine, pressure recovery system, desalination plant and ejector ramjet etc. The primary interest of this study is to set up an applicable model and operating conditions for an ejector in the condition of sonic and subsonic, which can be extended to the hydrogen fuel cell vehicle. Experimental and theoretical investigation on the sonic and subsonic ejectors with a converging-diverging diffuser was carried out. Optimization technique and numerical simulation was adopted for an optimal geometry design and satisfying the required performance at design point of ejector for hydrogen recirculation. Also, some sonic and subsonic ejectors with the function of changing nozzle position were manufactured precisely and tested for the comparison with the calculation results.

• Environmental Sciences Bulletin of The Korean Environmental Sciences Society
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• 제1권2호
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• pp.145-155
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• 1997

The effect of various supplies of lead singly and in combination with aluminium on growth and chlorophyll biosynthesis was investigated in 7-day-old Vigna angularis seedlings. Expose to 50 uM Pb or more drastically reduced root elongation rate. Significant depressions in root growth was observed within 1 day and no recovery of growth was seen over the duration of treatment period. Root elongation decreased depending on the Pb concentrations. Root growth inhibition was stronger than shoot growth inhibition. The initiation of lateral roots appeared to be more sensitive to Pb than the growth of main roots. Inhibition of root and shoot elongation by Pb was lessened by combined exposure of Pb and Al, suggesting that the presence of Al reverse the inhibitory effect of Pb alone. With the histochemical sodium rhodizonate method the rate of Pb uptake was dependent on the Pb concentration and exposure time of the roots to Pb salts. Pb was first deposited on the root surface and then translocated radially in the root cap cells. During a longer Pb administration (up to 72 h) Pb penetration was nonuniform, with accumulation within the cortex or endodermis. There was drastic reduction in chlorophyll content by Pb. The Pb inhibition of chlorophyll synthesis was concentration dependent. $\delta-Aminolevulinic$ acid dehydratase (ALAD) activity exhibited distinct inhibition from control. Reduction in chlorophyll content was accompanied by proportional changes in ALAD activity. Chlorophyll content and ALAD activity were less affected by combined exposure of Pb and Al, suggesting that Al has a protective effect against the inhibiting action of Pb on photosynthetic activity.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2008년도 춘계학술대회논문집
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• pp.256-259
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• 2008

Ejector system is a device to transport a low-pressure secondary flow by using a high-pressure primary flow. Ejector system is, in general, composed of a primary nozzle, a mixing section, a casing part for suction of secondary flow and a diffuser. It can induce the secondary flow or affect the secondary chamber pressure by both shear stress and pressure drop which are generated in the primary jet boundary. Ejector system is simple in construction and has no moving parts, so it can not only compress and transport a massive capacity of fluid without trouble, but also has little need for maintenance. Ejectors are widely used in a range of applications such as a turbine-based combined-cycle propulsion system and a high altitude test facility for rocket engine, pressure recovery system, desalination plant and ejector ramjet etc. The primary interest of this study is to set up an applicable model and operating conditions for an ejector in the condition of sonic and subsonic, which can be extended to the hydrogen fuel cell vehicle. Experimental and theoretical investigation on the sonic and subsonic ejectors with a converging-diverging diffuser was carried out. Optimization technique and numerical simulation was adopted for an optimal geometry design and satisfying the required performance at design point of ejector for hydrogen recirculation. Also, some ejectors with a various of nozzle throat and mixing chamber diameter were manufactured precisely and tested for the comparison with the calculation results.

• Clinical and Experimental Pediatrics
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• 제56권2호
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• pp.80-85
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• 2013

Purpose: Febrile seizures (FS) are seizures that occur between the age of 6 and 60 months, but its pathophysiology still is not fully understood. There is limited information about the correlation between levels of selenium and leptin with FS. This study aimed to determine the relationship between serum levels of selenium and leptin in children with FS. Methods: This case-control study was conducted in a University Hospital in Shahrekord, Iran, in 2011. The serum levels of selenium and leptin of 25 children with simple febrile seizure (case group) were compared with 25 febrile children without seizure (control group) in acute phase and after three months. The levels of serum selenium and leptin were measured by flame atomic absorption spectrophotometer and enzyme-linked immunosorbent assay method, respectively. Results: In acute phase, the mean serum level of selenium in case and control groups were $95.88{\pm}42.55$ and $113.25{\pm}54.43{\mu}g/dL$, respectively, and difference was not significant (P=0.415), but after three months, this level had a significant increase in both groups (P<0.001). In acute phase, the mean serum leptin level in case and control groups were $0.94{\pm}0.5$ and $0.98{\pm}0.84$ ng/mL, respectively, but difference was not significant (P=0.405). After three months, serum leptin level had no significant change in both groups (P=0.882). Conclusion: These observations suggest that serum levels of selenium and leptin have not specific relation with FS but overllay is lower, however, further study is recommended. Also selenium level in stress and acute phase was significantly lower than recovery phase.

• 대한한의학원전학회지
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• 제23권1호
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• pp.257-277
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• 2010

The purpose of this article is to oversee the theory of Chimibyeong(治未病). The aim of Chimibyeong theory is to prevent disease from occuring, worsening, being delivered and so on. In many books, the word Chimibyeong was used as an alternative name for Yangsaeng(養生) or used as a term of preventing a disease or used as a word meaning treating disease in the early stage. But after the period of "Nangyeong(難經)", people extend the meaning of Chimibyeong to all stages of a disease covering the healthy stage, the early stage, the progressive, and the recovery stage of a disease. Especially in urgent cases when pathogenic factor[邪氣] attacks patient to critical situations, it is also regarded as one way of Chimibyeong to repel pathogenic factor out as soon as possible with proper medicines. These days people suffer from increasing mental stress, lack of rest and human relationships, environmental pollution and chronic diseases and so on, and the situation will grow worse. Many governments employ the health policy where preventing disease takes the highest priority because by doing that they can save a huge budget and minimize the economic and social disorder. In this circumstances the idea of pursuing prevention in the theory of Chimibyeong will help people to maintain healthy conditions.

• Preventive Nutrition and Food Science
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• 제20권4호
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• pp.246-252
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• 2015

The hot water extract of leather carp (Cyprinus carpio nudus) has been used as a nourishing tonic soup and as an aid for recovery from physical fatigue. In this study, we investigated the effect of leather carp extract on exercise performance in mice. Swimming endurance and forelimb grip strength were assessed following oral administration of the extract (once per day for 7 days) at a dose of $0.5 mg/10{\mu}L/g$ body weight. After 7 days, mice given the leather carp extract had significantly greater swimming endurance [$105{\pm}18s$ (P<0.05); 52% longer than day 0] and forelimb grip strength [$1.18{\pm}0.05$ Newton (P<0.01); 17% greater than day 0]. The extract increased muscle mass, but had little effect on body weight. Following the swimming exercise, blood glucose, glutathione peroxidase, and superoxide dismutase levels in extract-fed mice were significantly higher (145%, 131%, and 106%, respectively) than in the saline control group. Blood levels of high-density lipoprotein cholesterol were also significantly increased (128%) in mice given the extract compared to the controls. These results suggest that leather carp extract can improve physical exercise performance and prevent oxidative stress caused by exhaustive workouts.

• 대한한의학회지
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• 제32권2호
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• pp.1-13
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• 2011

Background and Objective: Coptidis Rhizoma is a medicinal herb known for its antioxidant and anti-inflammatory effect. The purpose of this study was to examine the effects of CR on the experimental burn elicitation in vitro and in vivo. Material and Methods: In order to know the antioxidant effect on skin cell of mice after burn elicitation, superoxide dismutase (SOD) activity was measured. In vitro, the RAW 264.7 macrophage cells were treated with lipopolysaccharides for experimental inflammation. iNOS mRNA expression was observed after CR-treatment. In order to know effects on the skin regeneration in the burned mice, we counted the nitric oxide (NO) in blood. We also observed the histological structure in the epidermal basal layer and the dermal section, and we studied changes of angiogenesis in the capillaries surrounding the basal layer and dermal papilla. The changes of transcription of iNOS mRNA (inducible nitric oxide synthase mRNA) and changes of NF-${\kappa}$B (nuclear factor ${\kappa}$B) p65 positive reaction were also observed to investigate the changes of the stress in the skin. Results: The results indicated that CR has significant effects on the antioxidant effect on skin cells of mice after burn elicitation by increasing SOD activity in the in vitro test. It seemed that CR decreased the amount of NF-${\kappa}$B which induced the iNOS mRNA dose-dependently and suppress activating NO and angiogenesis. Furthermore, CR facilitated the process of skin recovery after experimental burn. Conclusion: CR can be applied for burned skin via antioxidant effect and skin regeneration.