• Korean Journal of Plant Resources
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• v.34 no.2
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• pp.144-155
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• 2021

This study was conducted to analyze community structure and species composition of Abies koreana forest. Field survey was carried out from June, 2019 to 2020, September. 121 plots (20×20 m) were set up, 5 herb layer plots (3×3 m) were constructed for each plot, and there, Diameter at Breast Height(DBH), height, environmental factor were measured. It was analyzed that water stress did not have a significant effect on the factors affecting the growth of A. koreana in Mt. Halla-san, and in the case of Mt. Deokyu-san, the more forest stands located at the ridge, the higher the tree density. It was found that the factors affecting the distribution of Abies koreana were not consistent according to the environment of study site.

• Journal of the Korea institute for structural maintenance and inspection
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• v.25 no.6
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• pp.19-26
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• 2021

The seismic isolation system have been applied in order to protect the collapse of bridge by seismic load and the vertical load transmitted from the superstructure. However, the failure and damages of non-shrinkage mortar, isolator and wedge in total 12 bridge were reported by Pohang Earthquake. In this study, the damage mechanism and behavior characteristics of elastomeric bearing by an earthquake were evaluated to consider the seismic isolation system including non-shrinkage mortar and the seat concrete of pier. To discuss the effect of installed wedge and damage mode of elastomeric bearing, the compressive-shear tests were carried out. Also, the mechanical behaviors and damage mechanism for each component of elastomeric bearing were evaluated by using finite element analysis. From the test results, the cracks were created at boundary between non-shrinkage mortar and seismic isolator and the shear loads were rapidly increased after bump into wedge. The cause for damage mechanism of seismic isolation system was investigated by comparing stress distribution of anchor socket and non-shrinkage mortar depending on wedge during earthquake.

• Journal of Life Science
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• v.31 no.1
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• pp.100-108
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• 2021

In the oral cavity, there are hundreds of microbial species that exist as planktonic cells or are incorporated into biofilms. The accumulation and proliferation of pathogenic bacteria in the oral biofilm can lead to caries and periodontitis, which are typical oral diseases. The oral bacteria in the biofilm not only can resist environmental stress inside the oral cavity, but also have a 1,000 times higher resistance to antibiotics than planktonic cells by genes exchange through the interaction between cells in the oral biofilm. Therefore, if the formation of oral biofilm is suppressed or removed, oral diseases caused by bacterial infection can be more effectively prevented or treated. In particular, since oral biofilms have the characteristic of forming a biofilm by gathering several bacteria, quorum sensing, a signaling system between cells, can be a target for controlling the oral biofilm. In addition, a method of inhibiting biofilm formation by using arginine, an alkali-producing substrate of oral bacteria, is used to convert the distribution of oral microorganisms into an environment similar to that of healthy teeth or inhibit the secretion of glucosyltransferase by S. mutans to inhibit the formation of non-soluble glucans. It can be a target to control oral biofilm. This method of inhibiting or removing the oral biofilm formation rather than inducing the death of pathogenic bacteria in the oral cavity will be a new strategy that can selectively prevent or therapeutic avenues for oral diseases including dental caries.

• Economic and Environmental Geology
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• v.53 no.6
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• pp.703-713
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• 2020

In many geological fields, including hydrogeology, it is of great importance to determine the heterogeneity of the subsurface media. This study briefly introduces the concept and theory of the method that can estimate the hydraulic properties of the media constituting the aquifer, which was recently introduced by Park (2020). After the introduction, the method was applied to the synthetic aquifer to demonstrate the practicality, from which various implications were drawn. The introduced technique uses a global optimization technique called the covariance matrix adaptation evolution strategy (CMA-ES). Conceptually, it is a methodology to characterize the aquifer heterogeneity by assimilating the groundwater level time-series data due to the imposed hydraulic stress. As a result of applying the developed technique to estimate the hydraulic conductivity of a hypothetical aquifer, it was confirmed that a total of 40000 unknown values were estimated in an affordable computational time. In addition, the results of the estimates showed a close numerical and structural similarity to the reference hydraulic conductivity field, confirming that the quality of the estimation by the proposed method is high. In this study, the developed method was applied to a limited case, but it is expected that it can be applied to a wider variety of cases through additional development of the method. The development technique has the potential to be applied not only to the field of hydrogeology, but also to various fields of geology and geophysics. Further development of the method is currently underway.

• Journal of Life Science
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• v.31 no.5
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• pp.527-535
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• 2021

Lysosomes are organelles surrounded by membranes that contain acid hydrolases; they degrade proteins, macromolecules, and lipids. According to nutrient conditions, lysosomes act as signaling hubs that regulate intracellular signaling pathways and are involved in the homeostasis of cells. Therefore, the lysosomal dysfunction occurs in various diseases, such as lysosomal storage disease, neurodegenerative diseases, and cancers. Multiple forms of stress can increase lysosomal membrane permeabilization (LMP), resulting in the induction of lysosome-mediated cell death through the release of lysosomal enzymes, including cathepsin, into the cytosol. Here we review the molecular mechanisms of LMP-mediated cell death and the enhancement of sensitivity to anticancer drugs. Induction of partial LMP increases apoptosis by releasing some cathepsins, whereas massive LMP and rupture induce non-apoptotic cell death through release of many cathepsins and generation of ROS and iron. Cancer cells have many drug-accumulating lysosomes that are more resistant to lysosome-sequestered drugs, suggesting a model of drug-induced lysosome-mediated chemoresistance. Lysosomal sequestration of hydrophobic weak base anticancer drugs can have a significant impact on their subcellular distribution. Lysosome membrane damage by LMP can overcome resistance to anticancer drugs by freeing captured hydrophobic weak base drugs from lysosomes. Therefore, LMP inducers or lysosomotropic agents can regulate lysosomal integrity and are novel strategies for cancer therapy.

• Journal of the Korea institute for structural maintenance and inspection
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• v.25 no.3
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• pp.77-84
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• 2021

In this study, flexural tests of prestressed high strength spun concrete (PHC) piles reinforced with infilled concrete and longitudinal rebars were conducted, where the longitudinal rebar ratio and the presence of sludge formed on the inner surface of PHC pile were set as key test variables. A total of six PHC pile specimens were manufactured, and their flexural behaviors including failure mode, crack pattern, longitudinal strain distribution in a section and end slip between external PHC pile and infilled concrete were measured and discussed in detail. The test results revealed that the flexural stiffness and strength increased as the longitudinal rebar ratio became larger, and that the sludge formed on the inner surface of PHC pile did not show any detrimental effect on the flexural performance. In addition to the experimental approach, this study presents a nonlinear flexural analysis model considering compatibility conditions and strain and stress distributions of the PHC piles and infilled concrete. The rationality of the nonlinear flexural analysis model was verified by comparing it with test results, and it appeared that the proposed model well evaluated the flexural behavior of PHC piles reinforced with infilled concrete and longitudinal rebars with a good accuracy.

• Economic and Environmental Geology
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• v.54 no.6
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• pp.615-627
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• 2021

The Baekildo fault, a dextral strike-slip fault developed in Baekil Island, Goheung-gun, controls the distribution of tuffaceous sandstone and lapilli tuff and shows a complex fracture system around it. In this study, we examined the spatial variation in the geometry and connectivity of the fracture system by using circular sampling and topological analysis based on a detailed fracture trace map. As a result, both intensity and connectivity of the fracture system are higher in tuffaceous sandstone than in lapilli tuff. Furthermore, the degree of the orientation dispersion, intensity, and average length of fracture sets vary depending on the along-strike variation in structural position in the tuffaceous sandstone. Notably, curved fractures abutting the fault at a high angle occur at a fault bend. Based on the detailed observation and analyses of the fracture system, we conclude as follows: (1) the high intensity of the fracture system in the tuffaceous sandstone is caused by the higher content of brittle minerals such as quartz and feldspar. (2) the connectivity of the fracture system gets higher with the increase in the diversity and average length of the fracture sets. Finally, (3) the fault bend with geometric irregularity is interpreted to concentrate and disturb the local stress leading to the curved fractures abutting the fault at a high angle. This contribution will provide important insight into various geologic and structural factors that control the development of fracture systems around faults.

• Journal of the Korea institute for structural maintenance and inspection
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• v.26 no.2
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• pp.84-91
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• 2022

This study investigated the behavior of out-of-plane skewed moment connections that were designed as IMFs, as per the Korean standards. A total of 14 finite element models were constructed with the consideration of two types (single- and double-sided connections) and four levels of skew angle (0°, 10°, 20°, and 30°). The results indicated that the skewed connections considered in this study met the acceptance criteria for IMFs given by the codes. However, the load-carrying capacities of skewed connections were decreased as the skew angle increased. For the connection with a skew angle of 30°, the peak load was noted to be 13% less and the energy dissipation capacity could be 26% less than that of non-skewed connection. In addition, because of the skewed nature, the stress distribution in the skewed beam flange near the connection was asymmetric and the stresses were concentrated on the beam inner flange. Column twisting induced by the skewed configuration was very small and negligible in the beam and column combination considered in this study.

• Geomechanics and Engineering
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• v.28 no.3
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• pp.299-311
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• 2022

Water-resisting key stratum (WKS) between coal seams is an important barrier that prevents water inrush from goaf in roof under multi-seam mining. The occurrence of water inrush can be evaluated effectively by analyzing the fracture of WKS in multi-seam mining. A "long beam" water inrush mechanical model was established using the multi-seam mining of No. 2+3 and No. 8 coal seams in Xiqu Mine as the research basis. The model comprehensively considers the pressure from goaf, the gravity of overburden rock, the gravity of accumulated water, and the constraint conditions. The stress distribution expression of the WKS was obtained under different mining distances in No. 8 coal seam. The criterion of breakage at any point of the WKS was obtained by introducing linear Mohr strength theory. By using the mechanical model, the fracture of the WKS in Xiqu Mine was examined and its breaking position was calculated. And the risk of water inrush was also evaluated. Moreover, breaking process of the WKS was reproduced with Flac3D numerical software, and was analyzed with on-site microseismic monitoring data. The results showed that when the coal face of No. 8 coal seam in Xiqu Mine advances to about 80 m ~ 100 m, the WKS is stretched and broken at the position of 60 m ~ 70 m away from the open-off cut, increasing the risk of water inrush from goaf in roof. This finding matched the result of microseismic analysis, confirming the reliability of the water inrush mechanical model. This study therefore provides a theoretical basis for the prevention of water inrush from goaf in roof in Xiqu Mine. It also provides a method for evaluating and monitoring water inrush from goaf in roof.

• Korean Journal of Agricultural and Forest Meteorology
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• v.24 no.4
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• pp.275-284
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• 2022

Changes in air temperature, CO₂ concentration and precipitation due to climate change are expected to have a significant impact on soybean productivity. This study was conducted to evaluate the climate change impact on growth and development of determinate soybean cultivar in the southern parts of Korea. The high temperature during vegetative period, which does not accompany the increase of CO₂ concentration, increased the canopy photosynthetic rate in soybean, but after flowering, the high temperature above the optimal ranges interrupts the photosynthetic metabolism. In yield and yield components, high temperature reduced both the pod and seed number and single seed weight, resulting in a reduction of total seed yield. On the other hand, the increase in CO₂ concentration dramatically increased the canopy photosynthetic rate over the whole growth period. In addition, high CO₂ concentration increased the number of pods and seeds, which had a positive effect on total seed yield. Under concurrent elevation of air temperature and CO₂ concentration, canopy photosynthesis increased significantly, but enhanced canopy photosynthesis did not lead to an increase in soybean seed yield. The increase in biomass and branch by enhanced canopy photosynthesis seems to be attributed to an increase in the total number of pods and seeds per plant, which compensates for the negative effects of high temperature on pod development. However, Single seed weight tended to decrease rapidly by high temperature, regardless of CO₂ concentration level. Elevated CO₂ concentration did not compensate for the poor distribution of assimilations from source to sink caused by high temperature. These results show that the damage of future soybean yield and quality is closely related to high temperature stress during seed filling period.