• Nuclear Engineering and Technology
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• 제51권2호
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• pp.432-438
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• 2019

In the study of nuclear structure, the fast timing technique can be used to measure the lifetime of excited states. In the paper, we have developed a new fast timing system, which is made up of two $LaBr_3:Ce$ detectors and a set of waveform sampling system. The sampling system based on domino ring sampler version 4 chip (DRS4) can digitize and store the waveform information of detector signal, with a smaller volume and higher timing accuracy, and the waveform data are performed by means of digital waveform analysis methods. The coincidence time resolution of the fast timing system for two annihilation 511 keV ${\gamma}$ photon is 200ps (FWHM), the energy resolution is 3.5%@511 keV, and the energy linear response in the large dynamic range is perfect. Meanwhile, to verify the fast timing performance of the system, the $^{152}Gd-2_1^+$ state form ${\beta}^+$ decay of $^{152}Eu$ source is measured. The measured lifetime is $45.3({\pm}5.0)ps$, very close to the value of the National Nuclear Data Center (NNDC: $46.2({\pm}3.9)ps$). The experimental results indicate that the fast timing system is capable of measuring the lifetime of dozens of ps. Therefore, the system can be widely used in the research of the fast timing technology.

• The Journal of Korean Physical Therapy
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• 제31권2호
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• pp.67-75
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• 2019

Purpose: Patients with brain damage suffer from limitations in performing the activities of daily living (ADL) because of their motor function and visual perception impairment. The aim of this study was to help improve the motor function and visual perception ability of patients with brain damage by providing them with virtual reality-based contents. The usability results of the patients and specialists group were also evaluated. Methods: The ADL contents consisted of living room, kitchen, veranda, and convenience store, similar to a real home environment, and these were organized by a rehabilitation specialist (e.g., neurologist, physiotherapist, and occupational therapist). The contents consisted of tasks, such as turning on the living room lights, organizing the drawers, organizing the kitchen, watering the plants on the veranda, and buying products at convenience stores. To evaluate the usability of the virtual reality-based visual cognitive rehabilitation service, general elderly subjects (n=11), stroke patients (n=7), stroke patients with visual impairment (n=4), and rehabilitation specialists (n=11) were selected. The questionnaires were distributed to the subjects who were using the service, and the subjective satisfaction of individual users was obtained as data. The data were analyzed using SPSS 21.0 software. The general characteristics of the users and the evaluation scores of the experts were analyzed using descriptive statistics. Results: The usability test result of this study showed that the mean value of the questionnaire related to content understanding and difficulty was high, between 4-5 points. Conclusion: The virtual reality rehabilitation service of this study is an efficient service that can improve the function, interest, and motivation of stroke patients.

• 한국융합학회논문지
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• 제12권1호
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• pp.49-55
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• 2021

최근에는 데이터베이스의 발달로 금융, 보안, 네트워크 등에서 생성된 많은 데이터가 저장 가능하며, 기계학습 기반 분류기를 통해 분석이 이루어지고 있다. 이 때 주로 야기되는 문제는 데이터 불균형으로, 학습 시 다수 범주의 데이터들로 과적합이 되어 분류 정확도가 떨어지는 경우가 발생한다. 이를 해결하기 위해 소수 범주의 데이터 수를 증가시키는 오버샘플링 전략이 주로 사용되며, 데이터 분포에 적합한 기법과 인자들을 다양하게 조절하는 과정이 필요하다. 이러한 과정의 개선을 위해 본 연구에서는 스모트와 생성적 적대 신경망 등 다양한 기법 기반의 오버샘플링 조합과 비율을 유전알고리즘을 통해 탐색하고 최적화 하는 전략을 제안한다. 제안된 전략과 단일 오버샘플링 기법으로 신용카드 사기 탐지 데이터를 샘플링 한 뒤, 각각의 데이터들로 학습한 분류기의 성능을 비교한다. 그 결과 유전알고리즘으로 기법별 비율을 탐색하여 최적화 한 전략의 성능이 기존 전략들 보다 우수했다.

• 한국프랜차이즈경영연구
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• 제10권3호
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• pp.13-23
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• 2019

Purpose - The recent franchise industry is rapidly developing. Some franchisees have a low barriers to entry and competition among companies is intensifying. In this dynamic competitive environment, companies need to focus on customer preferences, quality, and technical interfaces to gain competitive advantage. As a result, companies are required to measure the performance of service values in order to provide differentiated services from competitors. In the franchise industry, customer experience marketing of service values will enable companies to create new businesses. Franchise firms should explore a variety of services to increase service value and reduce failures. Research design, data, methodology - The questionnaire of this study was based on the previous research. Surveys were conducted on panels of online surveys. Surveys were conducted on the panel who had visited the restaurant franchise within the past month. The survey was conducted for about 7 days from February 13, 2019 to February 19, 2019. Total 300 samples, 293 were used in the analysis except for seven unfair questionnaires. Results - The findings of this study are as follows: Emotional, monetary, and reputation values have positive effects on cognitive and affective attitudes. Quality value and behavioral value did not effect cognitive attitude and affective attitude significantly. In addition, affective attitude has positive effect on loyalty, but cognitive attitude did not significant effect on loyalty. Conclusions - First, food-service franchise company should develop a service that enables customers to use the store conveniently. We need to develop a comfortable environment for our customers and provide intangible services. Second, food-service franchise company should provide a reasonable price service. Food-service franchise company needs to sell a high quality menu at a reasonable price to generate profits. Third, food-service franchise companies need to strategically respond to their reputation. In other words, food-service franchise company needs to constantly monitor the reputation of its customers and respond appropriately to market conditions. Fourth, food-service franchise company needs to develop a service method capable of emotional interaction with customers. Food-service franchise firms need to develop ongoing service methods and educate their staff.

• 한국컴퓨터정보학회논문지
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• 제26권3호
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• pp.1-7
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• 2021

본 논문에서는 Hybrid CDN/P2P 구조를 기반으로 최적화된 미디어 데이터 탐색과 전송을 수행하며 사용자의 요청 가능성 예측을 통한 선별적 저장을 통해 사용자로의 끊김없는 데이터 전송과 불필요한 트래픽의 감소를 가능하게 한다. 또한 전송지연 및 패킷 손실의 가능성을 최소화하여 실시간으로 미디어를 활용할 수 있도록 하는 새로운 미디어 관리 기법을 제안한다. 이를 위해 각 미디어를 논리적인 세그먼트로 나누어 구성하고 각 세그먼트에 대한 가중치를 지속적으로 계산하며 계산된 가중치에 따라 세그먼트 데이터의 저장 여부를 결정하도록 한다. 또한 네트워크상에 산재되어 있는 컴퓨팅 노드들을 거리에 따라 지역적 그룹으로 지정하고 해당 그룹 내에서 저장 공간을 효율적으로 공유하고 활용하도록 한다. 제안하는 기법의 효율성을 검증하기 위해 수행된 실험을 통해 제안하는 방식이 기존의 방법들에 비해 비교적 좋은 성능 평가가 도출되는 것을 확인하였으며 이는 전송과정에서 발생되는 초기 지연시간 감소와 끊김 없는 전송 모두를 가능하게 할 수 있음을 알 수 있다.

• Tuberculosis and Respiratory Diseases
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• 제85권2호
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• pp.147-154
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• 2022

Background: The expression of calcium signaling pathway molecules is altered in various carcinomas, which are related to the proliferation and altered characteristics of cancer cells. However, changes in calcium signaling in anti-cancer drug-resistant cells (bearing a T790M mutation in epidermal growth factor receptor [EGFR]) remain unclear. Methods: Afatinib-mediated changes in the level of store-operated Ca²⁺ entry (SOCE)-related proteins and intracellular Ca²⁺ level in non-small cell lung cancer cells with T790M mutation in the EGFR gene were analyzed using western blot and ratiometric assays, respectively. Afatinib-mediated autophagic flux was evaluated by measuring the cleavage of LC3B-II. Flow cytometry and cell proliferation assays were conducted to assess cell apoptosis and proliferation. Results: The levels of SOCE-mediating proteins (ORAI calcium release-activated calcium modulator 1 [ORAI1], stromal interaction molecule 1 [STIM1], and sarco/endoplasmic reticulum Ca²⁺ ATPase [SERCA2]) decreased after afatinib treatment in non-small cell lung cancer cells, whereas the levels of SOCE-related proteins did not change in gefitinib-resistant non-small cell lung cancer cells (PC-9/GR; bearing a T790M mutation in EGFR). Notably, the expression level of SOCE-related proteins in PC-9/GR cells was reduced also responding to afatinib in the absence of extracellular Ca²⁺. Moreover, extracellular Ca²⁺ influx through the SOCE was significantly reduced in PC-9 cells pre-treated with afatinib than in the control group. Additionally, afatinib was found to decrease the level of SOCE-related proteins through autophagic degradation, and the proliferation of PC-9GR cells was significantly inhibited by a lack of extracellular Ca²⁺. Conclusion: Extracellular Ca²⁺ plays important role in afatinib-mediated autophagic degradation of SOCE-related proteins in cells with T790M mutation in the EGFR gene and extracellular Ca²⁺ is essential for determining anti-cancer drug efficacy.

• Nutrition Research and Practice
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• 제15권3호
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• pp.396-410
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• 2021

BACKGROUND/OBJECTIVES: High-quality meal intake, including snacks, is necessary for optimal development during adolescence. The purpose of this study was to evaluate the nutritional intake of adolescents and the quality of their diet according to snack type, eating location, and sleep hours. SUBJECTS/METHODS: A survey of middle school students living in Seoul and Gyeonggi province was conducted using questionnaires and the 24-h recall method to collect data on the 1-day dietary intake of the students from March to May, 2018. The data were analyzed using SPSS 23.0 and the CAN program. RESULTS: The average nutritional intake status among the respondents showed that the energy intake was lower than the recommended, showing 1,914.8 kcal for middle school boys and 1,752.7 kcal for girls. In terms of the nutritional intake status by gender, only the consumption of protein and niacin were significantly higher in boys than girls (P < 0.05). According to the sleep amounts, vitamin C intake was significantly higher in the sleep-deprived group than in the sleep-moderate or sleep-recommended group (P < 0.05), but the intake did not meet the recommendation in any group. The lower density nutrients found in the index of nutritional quality according to eating places were vitamin C, calcium, iron, and folic acid. School meals showed a higher nutritional density in protein, vitamin B₁, and niacin compared to convenience store meals (P < 0.05). CONCLUSIONS: This study suggested that sleep amount, and eating place affected the dietary quality of adolescents.

• 인간식물환경학회지
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• 제24권3호
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• pp.277-283
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• 2021

Background and objective: This study was conducted to increase understanding of agriculture through agricultural experience programs for adolescents living in self-reliance residence hall, and to investigate changes in work performance ability through changes in hand function. Methods: There were 11 subjects, and the average age was 18.2 years, all males without disabilities. The agricultural experience program consists of a total of 10 sessions including orientation and watching videos on future agriculture, creating vegetable gardens, planting, managing each crop, harvesting, visiting the processing room, and selling at a local food store. Results: The change in agricultural literacy by the agricultural experience program positively improved from a score of 113.73 to 127.91 (p = .008). The changes by sub-item are as follows. The value and safety of agri-foods (p = .020) and agriculture and natural environment (p = .007) were significantly improved. The function and value of rural areas (p = .050), production of agricultural products (p = .160), processing and distribution of agricultural products (p = .248), and agricultural policies (p = .058) were not significantly changed. The simple function of the hands was measured by the number of pegs inserted during 30 seconds, and the assembly function was measured by the number of pegs inserted during 60 seconds. In the case of simple function, the dominant hand was improved from 14.82 to 15.83 (p = .014), andthe non-dominant hand was also significantly improved from 13.79 to 15.01 (p = .002). There was no significant improvement in the simple function (p = .153) and assembly function (p = .770) of both hands. Conclusion: It is considered that the agricultural experience program will enable youths living in self-reliance residence halls to enhance their understanding of agriculture as an occupation, and enable them to play a role as wise consumers by positively affecting improvements in their agricultural literacy and simple hand functions.

• 대한본초학회지
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• 제27권6호
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• pp.77-81
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• 2012

Objectives : The purpose of this research was to examine the oriental medical term 'Yukjin(in chinese, liuchen)' i.e. 'good long-term storage of the six oriental medicinal herbs'. Yukjin has meant the six sorts of drugs which were well known for the older they stored, the better efficacious they were. This research was carried out to obtain more conclusive information about the time and the reason of the giving a naming Yukjin, and to arrange Yukjin's properties, toxicities and processes. Methods : We investigated the documents recorded in the medical classics of Yukjin and did the current issues and recent experimental researches of these medicines. Results : 1. The properties and flavors of Yukjin are pungent and bitter. When they were stored for a long time after gathering, their toxicities and stimuli were growing thinner, regarded as positive clinically with age and they should be used after processing. 2. The efficacies of Yukjin are not always in proportion to storage period. In case, they are stored too long, their efficacies and qualities may be deteriorated though volatility or pungent flavors are enfeebled. Conclusions : Consequently, toxicities and strong flavors of Yukjin can be reduced in various processes. So the traditional theory of long-term preservation is not necessarily retained. It may be desirable to store them for 1 to 3 years after harvest, to safen their toxicities and adverse reactions in the way of processing. If we use them properly according to oriental medicine method, it will be effective on treating and preventing the various diseases.

• 방송공학회논문지
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• 제27권4호
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• pp.561-568
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• 2022

최근 대부분의 딥러닝 기반 동영상 물체 분할 방법들에서는 외부 메모리에 과거 예측 정보를 저장한 상태에서 알고리즘 수행을 하며, 일반적으로 메모리에 많은 과거 정보를 저장할수록 관심 물체의 다양한 변화에 대한 근거들이 축적되어 좋은 결과를 얻을 수 있다. 하지만 하드웨어의 제한으로 인해 메모리에 모든 정보를 저장할 수 없어 이에 따른 성능 하락이 발생한다. 본 논문에서는 저장되지 않는 정보들을 기존의 메모리에 추가적인 메모리 할당 없이 저장하는 방법을 제안한다. 구체적으로, 기존 메모리와 새로 저장할 정보들과의 어텐션 점수를 계산한 후에, 각 점수에 따라 해당 메모리에 새 정보를 더한다. 이 방법으로 물체 형체의 변화에 대한 정보가 반영되어 물체 변화에 대한 강인성이 높아져서 분할 성능이 유지됨을 확인할 수 있었다. 또한, 메모리의 누적 매칭 횟수에 따라 적응적으로 업데이트 비율을 결정하여, 업데이트가 많이 되는 샘플들은 과거의 정보를 더 기억하여 신뢰성 있는 정보를 유지할 수 있게 하였다.