• Journal of International Academy of Physical Therapy Research
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• v.6 no.2
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• pp.846-851
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• 2015

This neurological damage accelerates the infection reaction of cells and apoptosis at the time of reperfusion after ischemia occurs. BCL-2/BCL-2 allogeneic begeminum has a function of suppressing the apoptosis of cells, and thus it is inferred that the susceptibility of cells to apoptosis is determined by the amount of allogeneic begeminum present which is determined based on the amount of BAX. Ischemia was induced in SD mice by occluding the common carotid artery for 5 minutes, after which blood was re-perfused. NEES was applied to acupuncture points, at 12, 24, and 48 hours post-ischemia on the joksamri, Hapgok. Protein expression was investigated through BAX antibody immuno-reactive cells in the cerebral nerve cells and Western blotting. The results were as follows: In the present study as well, as a result of observation of the change in the number of the BAX reaction cells after the inducement of GI, there was the aspect of most of the BAX reaction cells being observed in the corpus striatum area of the GI group 24 hours after the inducement of ischemia. This revealed the same results as those of previous studies in which the change in the number of BAX reaction cells occurred in all areas while ischemia was in progress. The change in the expression of BAX protein after 24 hours showed that there was a very significant reduction in the NEES group compared to the GI group (p<.01). As a result, a greatest amount of change in the number of BAX immunoreactive cells related to apoptosis 24 hours after ischemia appeared in the NEES group. This study that ischemia increases the expression of BAX that induces apoptosis. Thus, it is determined that ischemia is the main cause of the apoptosis of neurons, and this study reveals that low frequency needle electrode electrical stimulation has the effect of blocking the apoptosis of neurons by reducing protein related to the apoptosis of cells that has increased after ischemia has occurred.

• Clinical and Experimental Reproductive Medicine
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• v.42 no.2
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• pp.67-71
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• 2015

Objective: Elevated serum progesterone (P) levels on triggering day have been known to affect the pregnancy rate of in vitro fertilization (IVF). This study aimed to identify the possible factors influencing serum P levels on triggering day in stimulated IVF cycles. Methods: Three hundred and thirty consecutive fresh IVF cycles were included in the study. All cycles were first attempts and were performed in a single infertility center. The indications for IVF were male factor infertility (n=114), ovulatory infertility (n=84), endometriosis (n=61), tubal infertility (n=59), unexplained infertility (n=41), and uterine factor infertility (n=39). A luteal long protocol of a gonadotropin-releasing hormone (GnRH) agonist (n=184) or a GnRH antagonist protocol (n=146) was used for pituitary suppression. Ovarian sensitivity was defined as the serum estradiol level on triggering day per 500 IU of administered gonadotropins (OS[a]) or the retrieved oocyte number per 500 IU of administered gonadotropins (OS[b]). Results: Univariate analysis revealed that the serum P level on triggering day was associated with the serum estradiol level on triggering day (r=0.379, p<0.001), the number of follicles ${\geq}14mm$ (r=0.247, p<0.001), the number of retrieved oocytes (r=0.384, p<0.001), and ovarian sensitivity (OS[a]: r=0.245, p<0.001; OS[b]: r=0.170, p=0.002). The woman's age, body mass index, antral follicle count, and basal serum follicle stimulating hormone and estradiol levels were not associated with serum P level on triggering day. The serum P level on triggering day did not show significant variation depending on the type or cause of infertility, pituitary suppression protocol, or the type of gonadotropins used. Conclusion: The serum P level on triggering day was closely related to the response to ovarian stimulation.

• Convergence Security Journal
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• v.15 no.3_1
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• pp.41-51
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• 2015

Human have more complicate and skilled ability for lying even cheat ourself. It is not easy to cheat unconscious things like sweat, eyes, or voice, but if some one cheat own self, he can cheat every of that. Lie is one of the way to spread our gene and our instinct make a lie. Every living organism even bacteria or virus use similar trick to survive. In human body, there are more complicate and profound mechanism for lying like breathe, sweat, eyes, face or voice. We can control some of that and make a fake, but it can't be perfect. Human also called 'Homo Fallax' cause we have a language and skill to lie with it. In present, we can detect lie with polygraph, but it has few weakness. So we try to use Vibraimage technology for resolve it. In this paper, we describe how to use Vibraimage for lie detection and the research history.

• Journal of the Korean Society of Physical Medicine
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• v.2 no.2
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• pp.243-250
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• 2007

Purpose : Shoulder subluxation is a very common problem in patients with hemiplegia with stroke. Prevention of the low tone subluxed shoulder has been an issue for physical therapists working with neurological patients for many years. Methods : This study reviewed the literature to definite the management and a cause of shoulder subluxation with hemiplegia patients after stroke. Various modalities have been suggested for realigning the glenohumeral joint, but their use is controversial. The purpose of this paper is to review critically the evidence base in order to inform the clinical decision-making process for physiotherapists working in neurology. Results : Literature has identified supports, strapping and functional electrical stimulation(FES) in the management of low tone shoulders. Following review of this evidence it is suggested that there is a lack of reliable and valid research evidence on which to base conclusions. The modalities with the best supporting evidence for realigning the low tone subluxed glenohumeral joint are the triangular sling, Harris hemi sling and the Rolyan humeral cuff used in a standing position and the lap board and arm trough while the patient is sitting. However, due to soft tissue adaptation with associated lack of movement, over-correction and the need for careful patient positioning these supports need to be evaluated for each patient and should be used only in appropriate situations. Conclusion : Similarly, there is a lack of evidence on the effects of long-term use to this equipment. Electrical stimulation is also thought to have potential in the treatment to subluxed low tone shoulders but additional research is required to clarify the parameters for use and the long-term effects of these forms of management.

• Journal of the Korean Institute of Educational Facilities
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• v.27 no.3
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• pp.3-14
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• 2020

The purpose of this study is to discuss the planning direction of educational spaces to support children's healthy and creative learning based on bio_philic theory. This study analyzed the characteristics of the application of biophilic patterns in children's education space through case analysis. The conclusion of this study is summarized as follows. As a result of the analysis of children's classroom space, the pattern of 'A(Visual connection with nature), F(Dynamic & Diffuse Light), K(Prospect)' shows high application rate, but the pattern of 'C(Non-Rhythmic Sensory Stimuli), G(Connection with Natural Systems), I(Material Connection with Nature)' shows low application rate. In particular, there is a lack of connection with patterns such as hearing, smell, touch, taste stimulation and water experience, and curiosity through exploration of nature about 'B(Non-visual connection with nature), E(Presence of Water), N(Risk/Peril)' changes in nature and ecosystem. In the corridor and rest space, the pattern of 'A(Visual connection with nature), D(Thermal & Airflow Variability), F(Dynamic & Diffuse Light), G(Connection with Natural Systems), K(Prospect)' shows high application rate, but 'B(Non-visual connection with nature)' shows low application rate. In addition, the application of patterns related to the stimulation of curiosity through direct exploration of nature and the exploration of the patterns of 'E(Presence of Water), N(Risk/Peril)' is insufficient. Therefore, in the case of classroom spaces, the active use of nature as it is should be considered within the scope that does not cause visual confusion, and it should provide an area that can be experienced through the five senses. And corridors and rest spaces should be designed to introduce more active natural elements as spaces to recover stress caused by learning. In other words, the characteristics of children's education facilities need to be connected between classroom space, corridor, rest space and external space. This study is meaningful in that it analyzes and derives the application characteristics of 'biophilic design' which affects the 'Attention Restoration' of children's educational spaces through foreign cases.

• Journal of The Korea Institute of Healthcare Architecture
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• v.21 no.4
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• pp.7-15
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• 2015

Purpose: The definition of healing and treatment is different between the East and the West. I suppose that the different definitions of them affect the notion of healing environment in two cultural area. Therefore the aim of this study is to consider the different perspective in healing environment between the East and the West. Methods: Relevant literature review around domestic and foreign reference in fields of medicine and architecture has been conducted to consider the purpose. Results: First, the perspective that the cause of disease stems from inside of body approaches the body from standpoint of healing for recovery. Healing is the way to conquer imbalance by entering into a connection with nature around body. The concept of healing could analyze that it come from relevant perspective. Second, the healing environment in the East is the place where the flow of Qi between, human and human, and, human and environment, keep a balance. The notion of healing environment in the East is the filed of relations. In the West, the notion of healing environment is the place where arouse fine emotions through sensory stimulations. Implications: Recently the studies of healing environment focus on deducing sensory stimulation factors scientifically in the perspective of the West. But the healing environment couldn't be possible without the notion of place of relations. In the future, the notion of healing environment as the field of relations in the East has to be concerned.

• Proceedings of the Ginseng society Conference
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• 2002.10a
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• pp.401-415
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• 2002

Lim and his coworkers (1987; 1988; 1989) have also found that all of total Ginseng saponin, panaxadiol-and panaxatriol-type saponins cause the increased secretion of catecholamines (CA) in a $Ca^{2+}$ -dependent fashion from the isolated perfused rabbit adrenal glands through the activation of cholinergic (both nicotinic and muscarinic) receptors. These CA secretory effects are partly due to the direct action on the rabbit adrenomedullary chromaffin cells. However, the present study was designed to examine the effect of total ginseng saponin on CA secretion evoked by activation of cholinergic nicotinic receptors in the isolated perfused model of the rat adrenal gland. Total ginseng saponin given (100 ${\mu}g$/20 min) into an adrenal vein did fail to produce alteration of spontaneous CA release from the rat adrenal medulla. Acetylcholine(5.32 mM)- and DMPP(100 ${\mu}M$, a selective nicotinic receptor agonist)-evoked CA secretory responses were reduced markedly after the pretreatment with the total ginseng saponin at a rate of 100 ${\mu}g$/6.2 ml/20 min, respectively. Pretreatment with total ginseng saponin also depressed greatly high potassium (56 mM, a membrane depolarizing agent)- and Bay-K-8644 (10 ${\mu}M$, a calcium channel activator)-induced CA secretions. Taken together, it is thought that total ginseng saponin can inhibit the releasing effect of CA evoked by nicotinic receptor stimulation from the isolated perfused rat adrenal medulla, which seems to be associated to the direct inhibition of influx through L-type calcium channel into the rat adrenomedullary chromaffin cells. It seems that there is species differences in the adrenomedullary catecholamine secretion between the rabbit and rat.

• Journal of Fashion Business
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• v.26 no.4
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• pp.112-122
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• 2022

The purpose of this study is to investigate the effect of using socks combined with EMS on ankle pain reduction and ankle function improvement in home training participants. In this study, the conductive fabric was combined using socks that can properly compress the ankle. First, VAS was measured during EMS training after fatigue was induced and compared with fatigue during rest. It was confirmed that the level of VAS after EMS training was lower than after rest and fatigue. It was also confirmed that EMS training, which combines EMS with socks, was effective in reducing pain. The experimental action is a measurement action of WBLT and lying posture, and the situation before and after EMS training was compared by performing 30 minutes on the treadmill to cause delayed muscle pain during exercise. As a result of this study, it was found that pain reduction and ROM function were improved when electrical stimulation was performed using EMS socks. It was also confirmed that the application of electrical stimulation to EMS socks effected on ankle fatigue and function improvement. From the study results, it is expected that wearing socks equipped with EMS significantly reduces ankle injuries and improves functional recovery for home training participants.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.9 no.4
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• pp.135-144
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• 2014

This study has examined how the childcare teachers have been evaluating themselves on system absorption who have been working in the house of the children at the time when the sight of the society has been expanding to the house of the children through the spread of the understanding of the importance of the role and the strengthening of the leadership of the diverse types of the leadership of the childcare teachers in the house of the children, and also this study has observed the main causes affecting such situations. This study has also analyzed the main causes such as the cause of self understanding on job satisfaction of the children's house teachers, the cause of self understanding on the leadership of the principal, demographic characters, and characters related with the place of work affecting the system absorption(Emotional Absorption, Normative absorption, and lasting absorption) with the children's house teachers as the objects working in the area of the City of Seoul. The results of the analysis have showed that job satisfaction, individual consideration, intellectual stimulation, giving motive, age, schooling, type and scale of facility, grade and others have been appeared to have been significantly affecting the self evaluation on system absorption demographically. In other words, the child care teachers have had higher degree of reaction to the system absorption in affirmative direction when they come into contact with the leadership of the principal in raising the intellectual stimulation, providing the motivation, and giving consideration individually, and when they have higher evaluation on the job satisfaction they them selves understand. Based on such results the principal of the house of the children should spread the leadership for the careful operation of the house of the children for the teachers more positively, and what has been required was giving and developing the diverse operation service for the elevation of the job satisfaction of the childcare teachers.

• The Korean Journal of Pain
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• v.19 no.1
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• pp.33-44
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• 2006

Background: Peripheral nerve injury leads to neuropathic pain, including mechanical hyperalgesia (MH). Nerve discharges produced by an injury to the primary afferents cause the release of glutamate from both central and peripheral terminals. While the role of centrally released glutamate in MH has been well studied, relatively little is known about its peripheral role. This study was carried out to determine if the peripherally conducting nerve impulses and peripheral glutamate receptors contribute to the generation of neuropathic pain. Methods: Rats that had previously received a left L5 dorsal rhizotomy were subjected to a spinal nerve lesion (SNL) or brief electrical stimulation (ES, 4 Hz pulses for 5 min) of the left L5 spinal nerve. The paw withdrawal threshold (PWT) to von Frey filaments was measured. The effects of an intraplantar (i.pl.) injection of a glutamate receptor (GluR) antagonist or agonist on the changes in the SNL- or ES-produced PWT was investigated. Results: SNL produced MH, as evidenced by decrease in the PWT, which lasted for more than 42 days. ES also produced MH lasting for 7 days. MK-801 (NMDAR antagonist), DL-AP3 (group-I mGluR antagonist), and APDC (group-II mGluR agonist) delayed the onset of MH when an i.pl. injection was given before SNL. The same application blocked the onset of ES-induced MH. NBQX (AMPA receptor antagonist) had no effect on either the SNL- or ES-induced onset of MH. When drugs were given after SNL or ES, MK-801 reversed the MH, whereas NBQX, DL-AP3, and APDC had no effect. Conclusions: Peripherally conducting impulses play an important role in the generation of neuropathic pain, which is mediated by the peripheral glutamate receptors.