• Transactions of the Korean Society of Mechanical Engineers B
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• v.22 no.11
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• pp.1521-1529
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• 1998

The objective of this study is to investigate the effects of the hemodynamics on the morphological changes of the human endothelial cells due to the blood flow by in vitro experiment and computer simulation. The morphological changes of the endothelial cells due to the t10w shear stress were observed in the laminar t10w chamber as a function of the exposure time. The observed shapes of the endothelial cells are used to the model shapes of the endothelial cells for numerical study and the pressure and the wall shear stress variations around the endothelial cells are calculated from the numerical results. The endothelial cells elongate along the t10w direction and lessen their heights in the flow field to reduce the pressure and the wall shear stress on the surface.

• Korea-Australia Rheology Journal
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• v.19 no.3
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• pp.133-139
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• 2007

Low density polyethylene nanocomposites were prepared by melt intercalating maleic anhydride grafted polyethylene and montmorillonite clay. It has been found that maleic anhydride has promoted strong interactions between polyethylene and montmorillonite, leading to the homogeneous dispersion of clay layers. Rheological experiments revealed that prepared nanocomposites exhibited shear thinning behaviour. Polyethylene nanocomposites exhibited an increase in steady shear viscosities compared to virgin polyethylene owing to strong polymer clay interactions. The tensile strength of nanocomposites was improved but elongation at break decreased considerably. Also, barrier properties improved significantly with montmorillonite content.

• KSBB Journal
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• v.5 no.4
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• pp.391-396
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• 1990

4.0$\times$10-3 (IU/cells/day) of maximum specific scu-PA production, which was higher than those by a 75$\textrm{cm}^2$ T-flask and conventional perfusion systems, was maintained by tube-type bioreactor at 0.35 (1/h) of perfusion rate corresponding to 0.15 (dynes/$\textrm{cm}^2$) of shear stress. The production of scu-PA is also increased as shear stress was slowly increased, which is similar to natural human blood circulation. The tube reactor proves that there may be no limitation of oxygen supply by showing 1.0 (1/h) of oxygen transfer coefficient at steady state and this system yields much lower shear stress of 0.3(dynes/$\textrm{cm}^2$) than that of 5-8(dynes/$\textrm{cm}^2$) by conventional agitation systems.

• Journal of computational fluids engineering
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• v.14 no.4
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• pp.101-108
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• 2009

We present a new finite-element scheme for direct numerical simulation of particle suspensions in simple shear flow of a viscoelastic fluid in 3D. The sliding tri-periodic representative cell concept has been combined with DEVSS/DG finite element scheme by introducing constraint equations along the domain boundary. Rigid body motion of the freely suspended particle is described by the rigid-shell description and implemented by Lagrangian multipliers on particle boundaries. We present the bulk rheology of suspensions through the numerical examples of single-, two- and many-particle problems, which represent a large number of such systems in simple shear flow. We report the steady bulk viscosity and the first normal stress coefficient, which show shear-thickening behavior for both properties.

• Proceedings of the KSME Conference
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• 2001.06e
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• pp.560-565
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• 2001

The objective of the present study is to investigate the characteristics for flow and wall shear stress in the aneurysm which is a local dilatation of the blood vessel. The numerical simulation using the commercial software for the laminar and steady flow were carried out over the diameter ratios(ratio of maximum diameter of aneurysm to the diameter of blood vessel) ranging from 1.5 to 2.5 and Reynolds number ranging from 900 to 1800. It was shown that a recirculating vortex occupied the entire bulge with its core located closer to the distal end of the bulge and the strength of vortex increased with increase of the Reynolds number and diameter ratio. Especially, for the Reynolds number of 1800 and diameter ratio of 2.5, the very weak secondary recirculating flow was produced at the left upper of the aneurysm. The position of a maximum wall shear stress was the distal end of the aneurysm(z=18mm) regardless of the Reynolds number and diameter ratios. But the maximum values of the wall shear stress increased in proportion to the increase of Reynolds number and diameter ratio.

• Korea-Australia Rheology Journal
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• v.17 no.4
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• pp.181-190
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• 2005

Rheological characterisation of flocculated kaolinite pulps has been undertaken to elucidate particle interactions underpinning the dewatering behaviour induced by flocculation with polyethylene oxide (PEO), anionic polyacrylamide (PAM A) and their blends. Shear yield stress $(\tau_y)$ analysis indicated that polymer mediated particle interactions were markedly amplified upon shear of PEG based pulps. In contrast, PAM A based pulps showed a significant decrease in yield values upon shear. Steady stress measurements analysed using a modified Ellis model indicated subtle differences between the respective linear viscoelastic plateaus of the pulps. Furthermore, modified shear thinning behaviour was evident in PEG based pulps. Estimation of elastic and viscous moduli (G', G') was made using dynamic stress analysis for comparison with values determined from vane measurements. Despite a noticeable difference in the magnitude of G' between the two methods, similar trends indicating sheared PEG-based pulps to be more elastic than PAM based pulps, were observed. Floc microstructural observations obtained in support of rheological properties indicate that PEG flocculant induces significantly more compact particle aggregation within the clay pulps under shear consistent with the yield stress data, in contrast to PAM A, or indeed unsheared PEG based pulps. Consequentially, sheared PEG based pulps show significantly improved dewatering behaviour. The implications of the results, potential benefits and drawbacks of flocculation with PEG and PAM A are discussed with respect to improvements in current dewatering processes used in the minerals industry.

• Geomechanics and Engineering
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• v.23 no.6
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• pp.535-546
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• 2020

The stress environment of deep rock masses is complex. Under the action of earthquakes or blasting, the strength and stability of anchored rock masses in fracture zones or faults are affected. To explore the variation in anchored rock masses under creep-fatigue loading, shear creep comparative testing of anchored marble specimens with or without fatigue loading is performed. Considering the damage variable of rock under fatigue loading, a rheological model is established to characterize the whole shear creep process of anchored rock masses under creep-fatigue loading. The results show that (1) the overall deformation of marble under creep-fatigue loading is larger than that under only shear creep loading, and the average deformation is increased by 18.3%. (2) By comparing the creep curves with and without fatigue loading, the two curves basically coincide when the first level stress is applied, and the two curves are stable with the increase in stress level. The results show that the strain difference among the specimens increases gradually in the steady-state stage and reaches the maximum at the fourth level. (3) The shear creep is described by considering the creep mechanical properties of anchored rock masses under fatigue loading. The accuracy of this creep-fatigue model is verified by laboratory tests, and the applicability of the model is illustrated by the fitting parameter R2. The proposed model provides a theoretical basis for the study of anchored rock masses under low-frequency earthquakes or blasting and new methods for the stability and reinforcement of rock masses.

• Steel and Composite Structures
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• v.29 no.2
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• pp.273-286
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• 2018

In recent years, significant progress has been made in developing design rules for stainless steel members, while the investigation on bolted connections is relatively limited, in particular at elevated temperatures. In this paper, experimental and numerical investigations on stainless steel bolted connections at ambient and elevated temperatures from the literature were reviewed. Firstly, the research program that focused on structural behavior of cold-formed stainless steel (CFSS) bolted connections at elevated temperatures carried out by the authors were summarized. Over 400 CFSS single shear and double shear bolted connection specimens were tested. The tests were conducted in the temperature ranged from 22 to $950^{\circ}C$ using both steady state and transient state test methods. It is shown that the connection strengths decrease as the temperature increases in the similar manner for the steady state test results and the transient state test results. Generally, the deterioration of the connection strengths showed a similar tendency of reduction to those of the material properties for the same type of stainless steel regardless of different connection types and different configurations. It is also found that the austenitic stainless steel EN 1.4571 generally has better resistance than the stainless steel EN 1.4301 and EN 1.4162 for bolted connections at elevated temperatures. Secondly, extensive parametric studies that included 450 specimens were performed using the verified finite element models. Based on both the experimental and numerical results, bearing factors are proposed for bearing resistances of CFSS single shear and double shear bolted connections that subjected to bearing failure in the temperature ranged from 22 to $950^{\circ}C$. The bearing resistances of bolted connections obtained from the tests and numerical analyses were compared with the nominal strengths calculated from the current international stainless steel specifications, and also compared with the predicted strengths calculated using the proposed design equations. It is shown that the proposed design equations are generally more accurate and reliable than the current design rules in predicting the bearing resistances of CFSS (EN 1.4301, EN 1.4571 and EN 1.4162) bolted connections at elevated temperatures. Lastly, the proposed design rules were further assessed by the available 58 results of stainless steel bolted connections subjected to bearing failure in the literature. It is found that the proposed design rules are also applicable to the bearing resistance design of other stainless steel grades, including austenitic stainless steel (EN 1.4306), ferritic stainless steel (EN 1.4016) and duplex stainless steel (EN 1.4462).

• KSCE Journal of Civil and Environmental Engineering Research
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• v.13 no.2
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• pp.191-199
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• 1993

Diffusion of a steady horizontal line source in a turbulent shear flow is simulated by numerically solving a steady two-dimensional advective diffusion equation. The computational result is compared with the analytic solution for uniform velocity and diffusivity distributions over the depth. The analytic solution for constant velocity and diffusivity overestimates the degree of vertical mixing. The normalized equation indicates that friction factor is the only physical parameter that governs the vertical diffusion process. Sensitivities of the diffusion process to the friction factor and initial source position are analyzed. The rate of vertical mixing varies approximately as the square root of the friction factor. The optimal source position, which gives the most rapid mixing, lies above the mid-depth and moves toward the water surface as the friction factor increases.

• Journal of Biomedical Engineering Research
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• v.18 no.2
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• pp.187-196
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• 1997

The three-dimensional flow analysis using the finite volume method is presented to compare the steady flow characteristics of blood with those of blood substitutes such as water and aqueous polymer solution in an idealized double branching model. The model is used to simlllate the region of the abdominal aorta near the celiac and superior mesenteric branches. Apparent viscosities of blood and the aqueous Separan solution are represented as a function of shear rate by the Carreau model, Water and aqueoiu Separan AP-273 500wppm solution are frequently used as blood substitutes in vitro experiments. Water is a typical Newtonian fluid and blood and Separan solution are non-Newtonian fluids. Flow phenomena such as velocity distribution, pressure variation and wall shear stress distribution of water, blood and polymer solution are quite different due to differences of the rheological characteristics of fluids. Flow phenomena of polymer solution are qualitatively similar to those of blood but the phenomena of water are quite different from those of blood and polymer solution. It is recommended that a lion-Newtonian fluid which exhibits very similar rheological behavior to blood be used in vitro experiments. A non-Newtonian fluid whose rheological characteristics are very similar to those of blood should be used to obtain the meaninylll hemodynamic data for blood flow in vitro experiment and by numerical analysis