• Title/Summary/Keyword: statistical significance

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Effectiveness of ultra-wide implants in the mandibular and maxillary posterior areas: a 5-year retrospective clinical study

  • So-Yeon Kim;Hyeong-Gi Kim;Pil-Young Yun;Young-Kyun Kim
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.49 no.1
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    • pp.13-20
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    • 2023
  • Objectives: Ultra-wide implants may be used as a replacement if existing implants fail. This study was conducted to evaluate the factors influencing the prognosis and failure of ultra-wide implants. Patients and Methods: This study evaluated whether sex, age, site, diameter, length, additional surgery, implant stability (primary and secondary), and reason for ultra-wide implant placement affect the 5-year survival and success rates and marginal bone loss (MBL) of ultra-wide implants. Seventy-eight ultra-wide implants that were placed in 71 patients (39 males and 32 females) from 2008 to 2010 were studied. One-way ANOVA analysis was conducted to evaluate the statistical significance of MBL according to the patient's sex, implant site, and diameter. Independent sample t-tests were used to determine the statistical significance of MBL analysis which was used to determine the significance of the 5-year success and survival rates related to the variables. One-way ANOVA was conducted to evaluate the statistical significance of sex, implantation site, diameter, and MBL. Independent sample t-tests were used to evaluate the correlation between implantability and MBL for implantation reasons, while additional surgery, length, and Kaplan-Meier analysis were used to evaluate 5-year survival and success rates. Results: The mean age of patients was 54.2 years with a survival rate of 92.3% and a success rate of 83.3% over a mean 97.8-month period of observation. MBL averaged 0.2 mm after one year of prosthetic function loading and 0.54 mm at the time of final observation. Success rates correlated with primary stability (P=0.045), survival rates correlated with secondary stability (P=0.036), and MBL did not correlate with any variables. Conclusion: Ultra-wide implants can be used to achieve secure initial fixation in the maxillary and mandibular molar regions with poor bone quality or for alternative purposes in cases of previous implant failure.

A Review of the Statistical Analysis used in Clinical Articles Published on Journal of Korean Neurosurgical Society

  • Kang, Wee-Chang
    • Journal of Korean Neurosurgical Society
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    • v.40 no.4
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    • pp.304-308
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    • 2006
  • Statistical analyses used in clinical articles published on the Journal of Korean Neurosurgical Society were identified and appropriateness of statistical aspects in reporting results was assessed. Forty seven clinical articles were selected in this study, which were published from February, 2005 to February, 2006 on the journal. The frequency of statistical analysis was as follows : descriptive statistics only 24 [51.1%]. one type of statistical method 10 [21.3%], two or more methods 13 [27.6%]. An assessment of statistical aspects was performed in 24 clinical articles reporting inferential statistics. Ten articles [41.7%] did not adequately describe or reference all statistical methods used. There were six articles [25.0%] not reporting the confidence level used as the critical criteria of the statistical significance. In thirteen articles [54.2%] it seems more appropriate to implement multivariate analyses in addition to univariate analyses. We recommend that the journal readers should concentrate on improving their knowledge of basic statistics and statistical review for manuscripts submitted should be sought from professionals in the fields of biostatistics and epidemiology.

A Comparative study on the Maternal Behavior between Mothers of Tic-disordeed Children and Mothers of Normal (Tic 장애아동과 정상아동의 어머니 양육태도의 비교연구)

  • 이주리
    • Journal of the Korean Home Economics Association
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    • v.33 no.5
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    • pp.177-186
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    • 1995
  • The purpose of this study was to investigate the differences in the maternal behavior between mothers of tic-disordered children and mothers of normal. The subjects of this study were 30 mothers of tic-disordered children from Seoul National University Hospital, Seoul National Mental Hospital and two personal mental practice offices, also, there were another 30 mothers of normal. Statistical methods selected for data analyses were freqences, t-test. The main results of this study were summerized as follows; 1. The maternal behavior of normal children was warmer than that of tic-disordered at the level of p<.001. 2. The maternal behavior of normal children was more acceptable than that of tic-disordered. But, no statistical significance. 3. Mothers of normal children were more extrovert than mothers of tic-disordered at the level of p<.01. 4. The maternal behavior of tic-disordered provoked more dependency than that of normal at the level of p<.001. 5. Mothers of tic-disordered controlled children more than those of normal. But, no statistical significance. 6. Mothers of tic-disordered evaluated children and themselves more negative than those of normal at the level of p<.001. 7. Mothers of tic-disordered have more dependent tendencies than those of normal. But, no statistical significant.

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A Penalized Spline Based Method for Detecting the DNA Copy Number Alteration in an Array-CGH Experiment

  • Kim, Byung-Soo;Kim, Sang-Cheol
    • The Korean Journal of Applied Statistics
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    • v.22 no.1
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    • pp.115-127
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    • 2009
  • The purpose of statistical analyses of array-CGH experiment data is to divide the whole genome into regions of equal copy number, to quantify the copy number in each region and finally to evaluate its significance of being different from two. Several statistical procedures have been proposed which include the circular binary segmentation, and a Gaussian based local regression for detecting break points (GLAD) by estimating a piecewise constant function. We propose in this note a penalized spline regression and its simultaneous confidence band(SCB) approach to evaluate the statistical significance of regions of genetic gain/loss. The region of which the simultaneous confidence band stays above 0 or below 0 can be considered as a region of genetic gain or loss. We compare the performance of the SCB procedure with GLAD and hidden Markov model approaches through a simulation study in which the data were generated from AR(1) and AR(2) models to reflect spatial dependence of the array-CGH data in addition to the independence model. We found that the SCB method is more sensitive in detecting the low level copy number alterations.

The Effects of Radix Ophiopogon japonicus on the NC/Nga Atopy Model (소엽맥문동(小葉麥門冬)이 NC/Nga 아토피모델에 미치는 영향)

  • Jang, Sung-Eun;Kim, Yoon-Bum
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.21 no.3
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    • pp.10-19
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    • 2008
  • Objective : To investigate the effects of Radix Ophiopogon japonieus on atopic dermatitis, I prepared DNCB(2,4-dinitrochlorobenzen) induced atopic dermatitis NC/Nga mice and observed the mice by four ways; eye observation, the number of skin behavior times, histological changes of skin and cytokine(Total IgE, IL-4, $IFN-{\gamma}$). Methods : After prepare Radix Ophiopogon japonicus extract, DNCB induced atopic dermatitis NC/Nga mice were divided into three groups. The first is Control group which was intact group. The second is Medication group which was orally medicated Radix Ophiopogon japonicus extract one time a day for consecutive 5 days. The third group is Application group which was applied Radix Ophiopogon japonicus extract externally one time a day for consecutive 5 days. After that, the effect of Radix Ophiopogon japonicus on atopic dermatitis was observed. Statistical analysis was performed by using Kmskal-Wallis test and statistical significance was set at less than 5%. Results : 1. Radix Ophiopogon japonicus showed some in both Medication group and Application At observation of skin morphologic change, effects to prevent erythema reaction on skin group. 2. At the number of scratching behavior times, Radix Ophiopogon japonicus showed an effect to decrease scratching behavior times, but there was no statistical significance among three groups. 3. At skin tissue H-E stain, Radix Ophiopogon japonicus showed an effect to prevent skin epidermal tissue damages and also showed that it could keep the skin healthy in both Medication group and Application group. Especially in Application group, the skin of mouse showed almost normal recovery. 4. At cytokines, there was no statistical significance among three groups in IgE and IL-4. But Radix Ophiopogon japonicus showed an significant effect to suppress $IFN-{\gamma}$ in both Medication group and Application group. There was no significant difference between two groups. Conclusion : Radix Ophiopogon japonicus has some effects on atopic dermatitis in both internal medication and external application.

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The Effect of Bee Venom Acupuncture(BVA) on acute Ankle Sprain : A Randomized Controlled Trial and double blinding - Pilot study (급성 족관절 염좌에 대한 봉약침 효과-무작위대조시험, 이중맹검)

  • Song, Ho-Seub
    • Journal of Pharmacopuncture
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    • v.8 no.2
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    • pp.11-16
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    • 2005
  • Objective : The aim of the study was to investigate the therapeutic effect of BVA in the treatment of patients with acute ankle sprain. Design : A prospective randomized double-blind study of BVA was conducted. Setting : The study was done in the Kyungwon University Seoul Hospital from August 1st, 2004 to June 15th, 2005. Patients : 30 patients diagnosed with acute ankle sprain, especially 2nd degree on the Ankle grade pain chart(AGPC) participated in the study, who were divided into two groups (A and B) randomly by a coordinator flipping a coin. Group A and B were relevant to control and BVA group respectively, of which a coordinator never informed any other participant involved. Eventually 13 of 17 in group A and 11 of 13 in Group B finished all the process of the clinical trial. Intervention : In both group A and B, The Procedure of acupuncture treatment was made similar by appearance that four acupoints such as 坵墟(GB40), 中封(LR4), 商丘(SP5), 解谿(ST41) of the injured side were selected and Normal saline aqua-acupuncture(control, as a placebo) or BVA was done and then acupuncture at 坵墟(GB40), 中封(LR4), 商丘(SP5), 解谿(ST41), 足三里(ST36), 陽陵泉(G34) of the affected side was given again. the needles were retained for 20 minutes under the infrared rays. The treatment was given daily for a week. Outcome Measures : Ankle-Hindfoot Scale (AHS) and Visual Analogue Scale(VAS) were followed by three treatments. Statistical Analysis : Analysis regarding variations in AHS and VAS is carried out by applying Mann-Whitney test and Wilcoxon signed rank test sign test with level of significance at 5%. Results : At the end of the treatment, there was significant statistical differences between the two groups in VAS and AHS as well, while at the 3rd day only a VAS showed statistical significance. In each group, both VAS and AHS showed statistical significance along with duration of treatment. Conclusions : BVA was thought to be effective alternatives for relieving symptoms of acute ankle sprain, although further study was needed on the large scale.

A study of the health related habits of dental technicians (치과기공사의 건강관련 생활습관에 관한 연구)

  • Kwon, Soon-Suk
    • Journal of Technologic Dentistry
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    • v.32 no.4
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    • pp.369-386
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    • 2010
  • Purpose: This study aims to present practical data available for the effective health management and improvement for the dental technicians by exploring the interrelationships between general characteristics of dental technicians and seven health related habits like drinking, smoking, breakfast, and snacks among the others(alameda 7). Methods: Out of the random selection of the registered dental offices of Dental Technicians Association of Korea, 2,000 working dental technicians were asked to fill out the questionnaire from January 19 to April 30, 2009. We collected the 1,502 sheets of the questionnaire and took frequency analysis, crosstabulation, t-test, and analysis of variance using SPSS Win 12.0 program. Results: Among the seven health related habits, 54.9% of the subject answered 'never do exercise' in the question of exercise habits, which is the most problematic of all. Hours of sleep and BMI were found to be quite low. Of the general characteristics, sex proved statistically significant to all the seven habits(p<.001). Marital status, job title, and health check-up showed statistical significance in six items among the seven habits. Age, monthly income, job position showed statistical meanings in five items among the seven habits. The frequency of break showed statistical significance in four items among the seven habits. Working environment showed statistical significance only in the item of hours of sleep among the seven habits(p<.05). Conclusion: This study proved that it is vital to educate the dental technicians to learn the right habits for enhancing their health and quality of life and motivate them to practice those habits.

The Structural Relationship about Country Image and Corporate Image of Exporting Goods under Global Trade Environment

  • Lee, Bong Soo
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.56
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    • pp.3-27
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    • 2012
  • The purpose of this thesis is to develop a relational model which can explain consumer selection for exporting goods and analyze the effect of corporate image on the relations between country image and consumer selection under global trade environment. The specific objectives are as follows: 1) to suggest a concept of consumer selection and measurement criteria, 2) to analyze correlations among country image, corporate image and consumer selection and 3) to find out the effect of corporate image on the relations between country image and consumer selection. The SPSS program for window and LISREL program were used to analyze the data for this study. The statistical method used in this study was the covariance structure analysis estimating parameters by maximum likelihood method. Path coefficients were tested for t-tests with a statistical significance level of .05. The conclusions of this study are as follows. First, significant correlations were observed among all sub-variables proposed in this study. In addition, significant correlations were detected among country image, consumer selection and corporate image. Second, a hypothetical model proposed in this study was mostly appropriate. Country image had a positive direct effect on consumer selection and corporate image with statistical significance. In addition, it has an indirect impact on consumer selection with statistical significance with corporate image as an intervening variable. Third, corporate image had a significant moderation effect in country image-consumer selection relations. As corporate image levels increased, the effect of country image on consumer selection increased as well. In other words, it has been confirmed that if corporate image levels are high, country image could end up with consumer selection.

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Statistical significance test of polynomial regression equation for Huff's quartile method of design rainfall (설계강우량의 Huff 4분위 방법 다항회귀식에 대한 유의성 검정)

  • Park, Jinhee;Lee, Jaejoon;Lee, Sungho
    • Journal of Korea Water Resources Association
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    • v.51 no.3
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    • pp.263-272
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    • 2018
  • For the design of hydraulic structures, the design flood discharge corresponding to a specific frequency is generally used by using the design storm calculated according to the rainfall-runoff relationship. In the past, empirical equations such as rational equations were used to calculate the peak flow rate. However, as the duration of rainfall is prolonged, the outflow patterns are different from the actual events, so the accuracy of the temporal distribution of the probability rainfall becomes important. In the present work, Huff's quartile method is used for the temporal distribution of rainfall, and the third quartile is generally used. The regression equation for Huff's quadratic curve applies a sixth order polynomial equation because of its high accuracy throughout the duration of rainfall. However, in statistical modeling, the regression equation needs to be concise in accordance with the principle of simplicity, and it is necessary to determine the regression coefficient based on the statistical significance level. Therefore, in this study, the statistical significance test for regression equation for temporal distribution of the Huff's quartile method, which is used as the temporal distribution method of design rainfall, is conducted for 69 rainfall observation stations under the jurisdiction of the Korea Meteorological Administration. It is statistically significant that the regression equation of the Huff's quartile method can be considered only up to the 4th order polynomial equation, as the regression coefficient is significant in most of the 69 rainfall observation stations.

Statistical tests for biosimilarity based on relative distance between follow-on biologics for ordinal endpoints

  • Yoo, Myung Soo;Kim, Donguk
    • Communications for Statistical Applications and Methods
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    • v.27 no.1
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    • pp.1-14
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    • 2020
  • Investigations of biosimilarity between reference drugs and test drugs required statistical tests; in addition, statistical tests to evaluate biosimilarity have been recently proposed. Ordinal outcome data has been observed in research; however, appropriate statistical tests to deal with ordinal endpoints for biosimilar have not yet been proposed. This paper extends existing design for ordinal endpoints. Using measure of nominal-ordinal association and relative distances between drugs are defined so that testing procedures are developed. Through simulation studies, we investigate type I error rate and power to show the performance of our suggested method. Furthermore, a comparison between the statistical tests and other designs is proviede to show significance of ordinal endpoints.