• Title/Summary/Keyword: statistical evidence

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A Study on the Quality Requirements of Administrative Data Using Statistical Purposes (행정정보의 통계적 활용을 위한 품질요건에 관한 연구)

  • Jang, On-Soon
    • Journal of Digital Convergence
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    • v.12 no.6
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    • pp.43-53
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    • 2014
  • This study aims to improve the openness of administrative data and to make extensive use of it in the academic and policy development, analyzing the quality requirements as the users' view of administrative data using statistical purposes. Conducted the exploratory analysis on the case of the Transaction-based Price Index of Housing, applying the administrative data of Realestate Transaction Management System in Korea, based on Denmark's 7 quality indicators for the statistical use of administrative data. According to the results of this study, the administrative data could improve the efficacy of the policy by facilitating the collection of the statistical data which help analyzing the actual market situations. On the other hand, the data have some constraints in adding the required items to producing the statistics, or improving the timeliness problem, due to the characteristics focused on the civil service.

A Study on the Methods for the Robust Job Stress Management for Nuclear Power Plant Workers using Response Surface Data Mining (반응표면 데이터마이닝 기법을 이용한 원전 종사자의 강건 직무 스트레스 관리 방법에 관한 연구)

  • Lee, Yonghee;Jang, Tong Il;Lee, Yong Hee
    • Journal of the Korean Society of Safety
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    • v.28 no.1
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    • pp.158-163
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    • 2013
  • While job stress evaluations are reported in the recent surveys upon the nuclear power plants(NPPs), any significant advance in the types of questionnaires is not currently found. There are limitations to their usefulness as analytic tools for the management of safety resources in NPPs. Data mining(DM) has emerged as one of the key features for data computing and analysis to conduct a survey analysis. There are still limitations to its capability such as dimensionality associated with many survey questions and quality of information. Even though some survey methods may have significant advantages, often these methods do not provide enough evidence of causal relationships and the statistical inferences among a large number of input factors and responses. In order to address these limitations on the data computing and analysis capabilities, we propose an advanced procedure of survey analysis incorporating the DM method into a statistical analysis. The DM method can reduce dimensionality of risk factors, but DM method may not discuss the robustness of solutions, either by considering data preprocesses for outliers and missing values, or by considering uncontrollable noise factors. We propose three steps to address these limitations. The first step shows data mining with response surface method(RSM), to deal with specific situations by creating a new method called response surface data mining(RSDM). The second step follows the RSDM with detailed statistical relationships between the risk factors and the response of interest, and shows the demonstration the proposed RSDM can effectively find significant physical, psycho-social, and environmental risk factors by reducing the dimensionality with the process providing detailed statistical inferences. The final step suggest a robust stress management system which effectively manage job stress of the workers in NPPs as a part of a safety resource management using the surrogate variable concept.

Detection of Imprinted Quantitative Traits Loci (QTL) for Reproductive and Growth Traits in Region of IGF II Gene on fig Chromosome (돼지 염색체상의 IGF II 유전자 인접 부위에서 번식 및 성장형질에 연관된 Imprinting 양적형질 유전자 좌위(QTL)의 탐색)

  • Lee, Hakkyo
    • Korean Journal of Animal Reproduction
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    • v.25 no.4
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    • pp.295-304
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    • 2001
  • Characterization of quantitative trait loci (QTL) was investigated in the experimental crosses between Berkshire and Yorkshire breed. A total of 525 F$_2$ progenies from 65 matting of F$_1$ Parents were produced. Phenotypic measurements included average daily gain (ADG), average back fat thickness (ABF), and loin eye area (LEA). To identify the presence of QTL for reproductive performance, birth weight (BWT) and body weight at 16 days (16DAY) were included as indirect trait. QTL segregation was deduced using 8 markers assigned to chromosome 2 (SSC2). Quantitative trait locus analyses were performed using interval mapping by regression under line-cross model. Presence of imprinting was tested under the statistical model that separated the expression of paternally and maternally inherited alleles. To set the evidence of QTL presence, significance thresholds were derived by permutation following statistical tests, respectively. Genome scan revealed significant evidence for three quantitative trait loci (QTL) affecting growth and body compositions, of which two were identified to be QTL with imprinting expression mode near the ICF II gene region. For average back fat thickness (ABF), a paternally expressed QTL was found on chromosome 2 (SSC2). A paternally expressed QTL affecting loin eye area (LEA) was found in the region of SSC2 where evidence of imprinted QTL was found for average back fat thickness (ABF). For average daily gain (ADG), QTL expressed with Mendelian mode was found on chromosome 2 (SS2). Also, QTL affecting average daily gain (ADC), was identified to be expressed with Mendelian express mode.

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The Feature of the Program components in the Meta Analysis Research : Evidence Based Program Development Perspective (메타분석연구에서 나타난 프로그램 구성요소의 실태 : 증거기반 프로그램 개발의 관점에서)

  • Seo, In Hae;Kong, Gye Soon
    • Korean Journal of Social Welfare Studies
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    • v.49 no.3
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    • pp.247-275
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    • 2018
  • In the absence of a research study on meta-analysis in terms of program development, the purpose of the study is to analyze the contents of the meta-analysis research studies which has been conducted for 18 years, and is to identify the level of program component evidence for the development of social work program. In order to achieve these purposes, the study analyzed the feature and usefulness of the 110 meta-analysis studies(5,781 program evaluation studies)published from 2010 to June 2017 in major academic journals related to the areas of the social welfare, psychology, counseling and health. The major findings are as follows. The 110 meta-analysis studies tended to narrow down the scope of the population, problems, and program types, but they also included a lot of heterogeneous types. In the statistical methods, there were relatively few studies to explain the factors behind the heterogeneity of program effectiveness. In addition, researchers tended to select program components arbitrarily with bias on specific components. The important program components with the statistical validity are as follows; the age of the subjects, the severity of the problem, the expertise of the providers, and the strength and activities of the intervention, The academic meanings of the study results was discussed, and the direction of future research was presented to increase the usefulness of the metaanalysis for program development.

A Study for Anatomical Evidence of Anxiety Using Magnetic Resonance Imaging in Patients with Panic Disorder and Complex Partial Seizure (공황장애와 복합부분간질 환자의 뇌자기공명촬영소견을 통한 불안의 해부학적 증거에 대한 연구)

  • Choi, Byung-Hwi;Lee, Young-Ho;Chung, Young-Cho
    • Korean Journal of Biological Psychiatry
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    • v.2 no.1
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    • pp.107-114
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    • 1995
  • This study was to investigate the anatomical evidence of anxiety. MRI was used to study 11 patients with panic disorder and 15 patients with complex partial seizure, and 21 controls. The regions of interest in the MRI were measured with computer-assisted planimetry using the AutoCad and digitizer. The following results were obtained ; 1) The mean age was 49.7(12.4) years in patients with panic disorder and 30.1(7.5) years in patients with complex partial seizure. 2) There were na signi ficant differences between 3 groups in the values of cerebral area, temporal lobe, caudate nucleus, hippocampus, parahippocampus, amygdala, third ventricle and VBR. The right parahippocampal region which attracted most attention in neurobiological studies regarding anxiety, tended to be larger in both study groups compared to the control group, but with no statistical significance. 3) There was lett-right reversal of temporal lobes in both study groups. And these are mainly due to asymmetrical increase in area of the temporal lobe on right side. These results suggest that temporal lobe, especially right temporal, is the anatomical correspondence of anxiety and functional activation of temporo-limbic system may be accompanied by the structural change of temporal lobe.

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An exploratory study for an evidence of electroencephalographic changes in isolated subjects for distant mental intention

  • Kim, Dae-Keun
    • Science of Emotion and Sensibility
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    • v.17 no.4
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    • pp.51-60
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    • 2014
  • This double-blind study, as a human experiment of nonlocality, investigated the effects of senders' intention on the central nervous system of a distant human receiver and it explored the roles that motivation might have in modulating these effects. Whole brain activity was measured in the receiver whom was asked to relax in a distant room for 16 minutes; the sending person directed intention of oneness toward the receiver during repeated variable-second epochs separated by variable-second non-intention epochs. The total length of intention epochs and that of nonintention epochs were balanced. Eighteen sessions were conducted. In 9 of those sessions, the sender was the receiver's lover. In another 9 of those sessions, the sender was just acquainted with the receiver before the session. The receiver's whole brain activity recorded during the intention epochs were compared with the same measures recorded during the nonintention epochs used as controls. The statistical difference between the intentions versus controls across 18 sessions was examined by paired-t test. In addition, subgroup analysis for the 9 couple sessions and 9 non-couple sessions were additionally examined by the same test. The effect of distant intentionality decreased slow waves or increased EEG fast waves mainly in frontal regions, and increased EEG coherence during the intention epochs. The effects was not statistically significant after Bonferroni correction, but the couple sessions combined showed the largest effect followed by all sessions combined. Non-couple sessions combined showed the smallest effect. The changes in EEG power mean that receiver participants became more alert during the intention epochs and the change in EEG coherence might be evidence of coherent heart influence on EEG activity. Planned comparison with specific hypothesis testing for the suggested changes in this study have to be followed for an evidence of electroencephalographic changes in isolated subjects for the distant mental intention.

A Study on the relations between change of productivity and conversion factor of the Accredited Hospitals based on Malmquist index (Malmquist 지수에 기초한 의료기관평가 대상 병원의 생산성 변동과 환산지수 변동에 관한 연구)

  • O, Dong-Il
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.1
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    • pp.125-137
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    • 2011
  • This study aims to know whether the Accreditation of Hospitals can help to improve productivity of hospital and affect the conversion factor. Based on the Malmquist productivity Index, the productivity of accredited hospital improves. There exists an tendency that as the scores of Accreditation rises, productivity increases. Also the higher the productivity, the lower the conversion factors in the rigid statistical evidence. This evidence is independent of hospital classification, geographical distribution, grouping. This evidence supports the productivity index can be included in the fee negotiations. It also means that rather than static efficiency, the multi-year change of productivity information can be usefully combined to set a conversion factor in Korean National Insurance Contract especially in the discussion of the structural change of payment system.

Association between Praziquantel and Cholangiocarcinoma in Patients Infected with Opisthorchis viverrini: A Systematic Review and Meta-Analysis

  • Kamsa-Ard, Supot;Laopaiboon, Malinee;Luvira, Vor;Bhudhisawasdi, Vajarabhongsa
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.11
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    • pp.7011-7016
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    • 2013
  • Background: The liver fluke, Opisthorchis viverrini, and the associated incidence of subsequent cholangiocarcinoma (CCA) are still a public health problem in Thailand, and praziquantel (PZQ) remains the antihelminthic drug of choice for treatment. Evidence in hamsters shows that repeated infection and PZQ treatments could increase the risk of CCA. However, the existing evidence in humans is inconclusive regarding increased risk of CCA with frequency of PZQ intake. Objectives: To investigate the relationship between number of repeated PZQ treatments and CCA in patients with O viverrini infection. Materials and Methods: The reviewed studies were searched in EMBASE, MEDLINE, ProQuest, PubMed and SCOPUS from inception to October, 2012 using prespecified keywords. The risk of bias (ROB) of included studies was independently assessed by two reviewers using a quality scale from the Newcastle-Ottawa Scale (NOS). Risk effect of PZQ was estimated as a pooled odds ratio (OR) with its 95% confidence interval (95%CI) in the random-effects model using DerSimonian and Laird's estimator. Results: Three studies involving 637 patients were included. Based on the random effects model performed in two included studies of 237 patients, the association between PZQ treatments and CCA was not statistical significant with a pooled OR of 1.8 (95%CI; 0.81 to 4.16). Conclusions: The present systematic review and meta-analysis provides inconclusive evidence of risk effect of PZQ on increasing the risk of CCA and significant methodological limitations. Further research is urgently needed to address the shortcomings found in this review, especially the requirement for histological confirmation.

An Empirical Study on the Effect of the Separation of Dispensary from Medical Practice (의약분업제도 도입효과에 대한 실증 분석)

  • Yoon, Ji-Woong;Kim, Yang-Kyun;Beak, Byung-Su
    • Health Policy and Management
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    • v.21 no.2
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    • pp.179-194
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    • 2011
  • Although there have been studies regarding the separating policy of dispensary and medical practice, little study have provided a concrete empirical evidence to what extent the policy objectives are achieved. In this paper, we try to provide empirical evidence whether the policy separating dispensary from medical practice achieved the policy objectives, which representatively are reducing the mis-use or over-use of anti-biotic prescriptions and medicines, and decreasing the government spending for the cost of pharmaceutical support. By comparing the average of the rate of change of the number of medicines prescribed, the rate of anti-biotics prescribed, and the government spending for the cost of pharmaceutical support between the areas where the separation policy was implemented and the exceptional areas, we concluded that it is difficult to conclude that the policy separating dispensary and medical practice achieved its policy objects, as it first announced to achieve in the introduction of the policy in 2000. However, the limitation of this study is that the data, that can thoroughly analyze the effect of separating policy of dispensary from medical practice, cannot be collected as expected. Hence, we could not use a parsimonious empirical model to evaluate the effect of the policy introduced in 2000. Rather we used a simple statistical method to extract enough empirical evidence fro m the data available. In the near future, we would expect to see more research that analyze the exact effect of policy separating dispensary and medical practice with concrete empirical model using more sophisticated dataset.

Using of the "Consolidated Standards of Reporting Trials:CONSORT" to heighten quality of Medical Education study (의학교육연구의 질을 향상시키기 위한 '연구보고의 표준' 의 활용)

  • Yoo, Ji-Soo
    • Korean Medical Education Review
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    • v.10 no.2
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    • pp.25-44
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    • 2008
  • Objectives: Through using of the strong research method like a Randomized Controlled Trial: RCT, we have to heighten quality of Medical Education study. I'd like to introduce "CONSORT", which stands for Consolidated Standards of Reporting Trials. Contents: Preventive Service Task Force(200l) in USA proposed Levels of evidence for enlarging evidence-based Practice: EBP. And the CONSORT was introduced, which encompasses various initiatives developed by the CONSORT Group to alleviate the problems arising from inadequate reporting of randomized controlled trials (RCTs). the CONSORT has 13 guides like these: 1. How participants were allocated to interventions 2. Scientific background and explanation of rationale 3. Eligibility criteria for participants. The settings and locations where the data were collected. 4. Precise details of the interventions intended for each group and how and when they were actually administered 5. Specific objectives and hypotheses 6. Clearly defined primary and secondary outcome measures, When applicable. any methods to enhance the quality of measurements (e.g., multiple observations, training of assessors) 7. How sample size was determined. When applicable, explanation of any interim analyses and stopping rules 8. Method used to generate the random allocation sequence, Details of any restriction [of randomization] 9. Method used to implement the random allocation sequence 10. Who generated the allocation sequence, who enrolled participants. and who assigned participants to their groups 11. Whether or not participants, those administering the interventions, and those assessing the outcomes were blinded to group assignment. If done, how the success of blinding was evaluated 12. Statistical methods used to compare groups for primary outcome(s), Methods for additional analyses, such as subgroup analyses and adjusted analyses 13. Flow of participants through each stage (a diagram is strongly recommended) Specifically, for each group report the numbers of participants randomly assigned. receiving intended treatment, completing the study protocol. and analyzed for the primary outcome. Results and Conclusion: Randomized Controlled Trial: RCT guided of CONSORT will contribute to do stronger evidence-based medical studies.