• 한국방사선학회논문지
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• 제12권4호
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• pp.541-547
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• 2018

흉부 디지털 단층합성(chest digital tomosynthesis, CDT) 검사 시 관전압 및 감도(sensitivity) 변화에 의한 선량감소 효과와 정량적 평가로 선량 최적화 조건을 평가하고자 한다. 관전압 125 kV, 135 kV 설정에 따른 sensitivity 200, 320, 400 변화하여 팬텀의 CDT 영상을 획득하였다. 감도와 관전압 변화 따른 선량과 면적선량(DAP)을 평가하였다. 화질평가는 최대신호 대 잡음비(PSNR), 대조도 대 잡음비(CNR), 신호 대 잡음비(SNR)를 image J를 이용하여 분석하였다. 선량은 14~23%, 면적선량은 13~26% 정도 sensitivity 200, 125 kV에 비해 측정치가 낮아졌고, sensitivity 가 높아짐에 따라 감소율 커짐을 알 수 있었다. PSNR은 27dB 이상으로 모두 의미 있는 수치였고, CNR, SNR은 sensitivity가 낮을수록 우수했으나, 항목마다 통계의 유의성은 달랐다. CNR과 SNR 모두 sensitivity 320, 135 kV가 sensitivity 200, 125 kV와 통계적으로 유의하지 않았다(p>0.05). CDT는 감도, 관전압과 디지털 촬영의 장비의 장점인 보정능력을 이용하여 더 작은 선량으로 화질을 유지 시킬 수 있다.

• Journal of Korean Neurosurgical Society
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• 제29권1호
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• pp.108-112
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• 2000

Objective : Many authors suggest that patients with traumatic subarachnoid hemorrhage(tSAH) visible on first CT after heve injury had a significantly worse prognosis than patients who do not. The aim of this study is to identify patients with tSAH who present with a bad prognosis by reviewing their clinicoradiological features and plan appropriate treatments. Patients and Methods : We reviewed and analysed the factors that influenced discharge outcomes in 172 patients with tSAH for a 3-year period. The outcome was divided into good(good recovery and moderate disability of glasgow outcome scale) and good(severe disability, vegetative state and death). Results : A regression analysis of statistical significant factors(p<0.05) among the clinical and CT features ranked them by descending order of contribution to Glasgow Outcome Scale(GOS) scores at the time of discharge from acute hospitalization as follows 1) clinical : admission Glasgow Coma Scale(GCS), hypotension, CT grade, abnormal APTT, skull fracture, hyperglycemia(>160mg/dl), hypoxia, operation, 2) CT : basal cistern effacement(BCE), mass lesion, cortical sulcal effacement(CSE), midline shift. Conclusion : We have also experienced that the CT grading scale proposed by Green et al is a simple and useful prognostic factor. The authors believe that the patients with high CT grade need adjuvant therapies as of well surgery but it seems mandatory to consider early identification and correction of hypotension, hyperglycemia, and hypoxia in emergency setting.

• 대한치과교정학회지
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• 제47권2호
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• pp.77-86
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• 2017

Objective: The aim of this study was to evaluate the skeletal and dentoalveolar changes after miniscrew-assisted rapid palatal expansion (MARPE) in young adults by cone-beam computed tomography (CBCT). Methods: This retrospective study included 14 patients (mean age, 20.1 years; range, 16-26 years) with maxillary transverse deficiency treated with MARPE. Skeletal and dentoalveolar changes were evaluated using CBCT images acquired before and after expansion. Statistical analyses were performed using paired t-test or Wilcoxon signed-rank test according to normality of the data. Results: The midpalatal suture was separated, and the maxilla exhibited statistically significant lateral movement (p < 0.05) after MARPE. Some of the landmarks had shifted forwards or upwards by a clinically irrelevant distance of less than 1 mm. The amount of expansion decreased in the superior direction, with values of 5.5, 3.2, 2.0, and 0.8 mm at the crown, cementoenamel junction, maxillary basal bone, and zygomatic arch levels, respectively (p < 0.05). The buccal bone thickness and height of the alveolar crest had decreased by 0.6-1.1 mm and 1.7-2.2 mm, respectively, with the premolars and molars exhibiting buccal tipping of $1.1^{\circ}-2.9^{\circ}$. Conclusions: Our results indicate that MARPE is an effective method for the correction of maxillary transverse deficiency without surgery in young adults.

• Journal of Radiation Protection and Research
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• 제23권4호
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• pp.251-257
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• 1998

국내 원전에 적용하기 위한 기체 방사성 물질 확산 및 피폭 평가 코드를 개발하였다. 정상 운전에 의한 기체 방사성 물질 확산 및 피폭 평가에는 직선 궤도 가우시안 플륨 모델을 사용하는 XOQDOQ 코드가 사용되어 왔다. 본 연구에서는 이 코드의 단점인 발전소 주변 지역에서의 바람 방향의 영향, 산악 지형에 대한 모델, 습식 침적에 대한 개선이 이루어졌다. 현실적인 유효 고도 보정 및 산악 침투 모델을 통해서 산악 지형에 대한 고려를 하였고, 바람 발생 확률 빈도를 수정하여 직선 궤도 모델을 보완하였다. 개발된 코드는 영광원전의 주민피폭선량평가를 위해 채택되었으며, 산악이 많은 우리 나라 다른 발전소에 적용하기 위해 산악지형 입력변경을 통하여 적절히 사용될 수 있을 것이다.

• 대한치과교정학회지
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• 제23권4호
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• pp.707-724
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• 1993

The purpose of the study is to estimate hard and soft tissue changes after orthognathic surgery for the correction of the mandibular prognathism and to describe interrelationship and ratios of soft and hard tissue changes. The presurgical and postsurgical lateral cephalograms of 31 treated patients(17 males and 14 females) was used ; these patients had received combined orthodontic-surgical treatment by means of a bilateral sagittal split ramus osteotomy. Their ages ranged from 16 to 31 years and mean age was 21.4 years. A computerized cephalometric appraisal was developed and used to analyse linear and angular changes of skeletal and soft tissue profile. The statistical elaboration of the data was made by means of $SPSS/PC^+$. The results of the study were as follows : 1. The correlations of soft and hard tissue horizontal changes were significantly high and the ratios were $97\%$ at LI, $107\%$ at ILS, and $93\%$ at Pog'. 2. The correlations of vertical changes at Stm, LI and horizontal changes at Pog were high$(26\%)$ and at the other areas were not statistically high. 3. The correlations of soft ad hard tissue vertical changes were not significantly high in all areas except Gn' $(30\%)$ and Me' $(56\%)$. 4. The soft tissue thickness was significantly decreased in upper lip and increased in lower lip, and the amount of changes after surgery was reversely correlated with initial thickness. 5. The facial convexity was increased and relative protrusion of upper lip was increased and that of lower lip was decreased. 6. The upper to lower facial height(Gl-Sn/Sn-Me') was increased and upper to lower jaw height(Sn-Stms/Stmi-Me') was increased.

• 생물정신의학
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• 제22권4호
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• pp.173-178
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• 2015

Objectives Previous genome-wide association studies have indicated the association between ankyrin 3 (ANK3) and the vulnerability of schizophrenia. We investigated the association between single nucleotide polymorphisms (SNPs) covering the whole ANK3 locus and schizophrenia in the Korean population. Methods The study subjects were 582 patients with schizophrenia and 502 healthy controls. Thirty-eight tag SNPs on ANK3 and five additional SNPs showing significant association with schizophrenia in previous studies were genotyped. Results Three (rs10994181, rs16914791, rs1938526) of 43 SNPs showed a nominally significant association (p < 0.05) with at least one genotype model. But none of these associations remained significant after adjusting for multiple testing errors with Bonferroni's correction. Conclusions We could not identify a significant association between ANK3 and schizophrenia in the Korean population. However, three SNPs showing an association signal with nominal significance need to be investigated in future studies with higher statistical power and more specific phenotype crossing the current diagnostic categories.

• 대한토목학회논문집
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• 제9권4호
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• pp.113-124
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• 1989

인공위성 데이타 정보의 용용분야는 여러가지가 있으나, 본 연구에서는 LANDSAT MSS데이타와 TM데이타를 처리 분석하여 서울시 토지이용정보를 경년변화에 따라 추출하고자 하였다. 사용 데이터는 MSS(72, 79, 81, 83년), TM(85년)이며 입수된 데이타를 전처리를 통해 기하보정, 디지타이징(행정구역에 따라) 등을 하고, 유효 band 선정 및 filtering을 통하여 정확도를 높인 후 MLC(Maximum Likelihood Classifier)로 토지이용분류를 실시하였다. 토지이용분류시 training field 선정 자료로는 현지조사자료, 지형도, 항공사진을 참조하였고, 분류결과의 정확도는 각각 그 당시의 통계자료를 토대로 하여 비교해 보았다. 분석결과, 서울시의 도시지역은 72년 (25.3 %), 81년 (43.0 %), 85년 (51.9 %)로 증가되었고, 이에 대해 삼림은 72년(39.0 %)에서 85년(28.4 %)로 점차 감소되고 있었다. 이상과 같이 토지이용 경년변화를 추출함으로써 도시의 토지 이용상황 monitoring에는 반복 주기를 가지는 인공위성 데이터의 활용이 경제적이며 효과적임을 알 수 있었다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권17호
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• pp.7443-7447
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• 2014

Aim: Little is known about the genetic associations with Basal cell carcinoma (BCC) risk in non-Caucasian populations, in which BCC is rare, as in Korea. We here conducted a pilot genome-wide association study (GWAS) in 12 patients and 48 standard controls. Method: A total of 263,511 SNPs were analyzed with the Illumina HumanOmni1 Quad v1.0 DNA Analysis BeadChip for cases and Korean HapMap 570K for controls. Results: SNP-based analyses, based on the allele genetic model with adjustment for sex and age showed suggestive associations with BCC risk for 6 SNPs with a P-value (P < 0.0005). However, these associations were not statistically significant after Bonferroni correction: rs1040503, rs2216491, rs13407683, rs4751072, rs9891263, and rs1368474. In addition, results from gene-based analyses showed suggestive associations with BCC risk for 33 candidate genes with a P-value (P <0.0005). Consistent with previous GWAS and replication studies in Caucasian populations, PADI6, RHOU and SLC45A2 were identified as having null associations with BCC (P > 0.05), likely due to the smaller sample size. Conclusions: Although this was a small-scale negative study, to our knowledge, we have conducted the first GWAS for BCC risk in an Asian population. Further large studies in non-Caucasian populations are required to achieve statistical significance and confirm these findings.

• 치과방사선
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• 제6권1호
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• pp.27-31
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• 1976

A study was performed to investigate the size of pharynegeal cavity and sexual differences between Korean adult male and female by introducing linear analysis of the lateral cephalogram. The radiograms were composed of 46 adult males aged 24.64 and 52 adult females aged 22.74 respectively. In order to study and measure the pharyngeal area the following skeletal landmarks were selected: S, N, A, Ptm, B, H, H', M, S' N, FH and CV, and the angle CV-FH was measured to provide a factor for correction of error resulting from improper head positioning of subjects, especially in the relative positions of A and H, while radiography. All points to be measured were projected at right angles to the Frankfort plane. For the purpose of measuring the anteroposterior dimensions of pharyngeal cavity the distances were measured in A-Ptm, A-S, S-Ptm and CV-H, and vertical measurements were made in SN-A, SN-PNS, SN-H' and M-H'. The obtained results were as follows: 1. The pharyngeal cavity is broader in the vertical than in the anteroposterior diameter in both sex and the maxium sexual differences were showed in the distances between SN and H', and minimal sexual differences in the distances between S and Ptm. 2. In general, the measurements of male were larger than those of female in the anteroposterior dimensions of pharyngeal cavity, but the distances bet-ween A and S, between CV and H showed significant sexual differences when evaluated statistically. 3. All of the measurements were larger in male than in female in vertical dimensions of pharyngeal cavity, and there were statistical significances of sexual differences in all variables.

• 한국해양학회지:바다
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• 제6권1호
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• pp.35-39
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• 2001

해저면의 지형과 형상을 조사하기 위해 획득되는 다중빔 음향측심자료는 조사선의 움직임과 빔의 위치에 따른 음압의 보정부족 등에 기인하는 이상치를 포함하고 있다. 이 연구에서는 자기회귀이동평균(ARMA)기법을 이용하여 이상치에 의해 왜곡된 자료를 보정해주는 통계학적 절차를 소개하고 이를 동해에서 얻어진 자료에 적용하였다. 이 방법에서는 자료의 자기 상관을 1차 자기회귀모형 AR(1)으로 표현하고 이를 추정한 후 추정된 모형에 현저하게 부합하지 않는 자료(이상치)는 추정된 모형을 인용하여 수정한다. 이러한 방법을 이상치가 발견되지 않을 때까지 반복적으로 되풀이한다. 자료의 처리결과 해저지형을 나타내는 신호에 비해 월등히 큰 이상치들이 대부분 제거되었음을 볼 수 있다.