• KSII Transactions on Internet and Information Systems (TIIS)
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• 제14권3호
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• pp.924-942
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• 2020

The facial expression is diverse and various among persons due to the impact of the psychology factor. Whilst the facial action is comparatively steady because of the fixedness of the anatomic structure. Therefore, to improve performance of the action unit recognition will facilitate the facial expression recognition and provide profound basis for the mental state analysis, etc. However, it still a challenge job and recognition accuracy rate is limited, because the muscle movements around the face are tiny and the facial actions are not obvious accordingly. Taking account of the moving of muscles impact each other when person express their emotion, we propose to make full use of co-occurrence relationship among action units (AUs) in this paper. Considering the dynamic characteristic of AUs as well, we adopt the 3D Convolutional Neural Network(3DCNN) as base framework and proposed to recognize multiple action units around brows, nose and mouth specially contributing in the emotion expression with putting their co-occurrence relationships as constrain. The experiments have been conducted on a typical public dataset CASME and its variant CASME2 dataset. The experiment results show that our proposed AU co-occurrence constraint 3DCNN based AU recognition approach outperforms current approaches and demonstrate the effectiveness of taking use of AUs relationship in AU recognition.

• 한국임상약학회지
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• 제22권2호
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• pp.153-159
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• 2012

Licorice is a very useful herbal medicine frequently prescribed, but glycyrrhizin, one of its components, can cause pseudoaldosteronism presenting hypokalemia, metabolic alkalosis and hypertension as a result of prolonging a biological half-life of systemic steroid by strongly inhibiting the enzyme $11{\beta}$-hydroxysteroid dehydrogenase type 2. The risk factors for this side effect are still unclear. Here, 479 hospitalized patients taking herbal medicines including licorice for more than five days were recruited to analyze their serum potassium levels, under following parameters ; age and gender of patient, dose and period of licorice, disease state such as hypertension and with or without diuretics. They were divided into the non-occurrence group (over 3.5 mEq/L) and the occurrence group (under 3.5 mEq/L) of hypokalemia based on serum potassium levels during hospitalization. The average ages of the non-occurrence group and the occurrence group were $52.6{\pm}17.8$ and $68{\pm}10.5$, respectively (p < 0.001). But there were no noticeable differences in the daily dose of licorice, days of taking, and total dose between groups. Regression analysis showed that odd ratio of age (>60) and taking diuretics inducing hypokalemia was 3.5 (95%CI 1.5-8.1), 4.6 (95%CI 2.0-10.9) that indicates significant correlation with hypokalemia. Based upon this analysis, it is imperative to monitor regularly the risk of pseudoaldosteronism or hypokalemia not only when administered licorice of high dose for long period but also when combined it with diuretics causing hypokalemia to the elderly patients over 60 year old.

• The Korean Journal of Physiology
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• 제6권2호
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• pp.1-8
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• 1972

A study was planned to see if the mammillary bodies have any influence upon orienting response Thirty-nine male rats were divided into two groups. One group of animals received electrolytic lesion of the mammillary bodies through stereotaxically implanted electrodes (mammillary body group), and the other group received the same treatment short of electrolytic lesion(operated control group). All animals were tested for orienting response 3 weeks after surgery. Orienting response was regarded as elicited when an animal in alertness ceased ongoing activity upon 1,000 Hz tone presentation and/or turned head toward the source of stimulus. Weak (momentary and inconspicuous) and strong (marked and more persistent) responses were discriminated. Occurrence and duration of orienting response were measured, and the rate of habituation was estimated in 20 trials. Shift of attention from sound to light stimulus (10 trials) as well as orienting response of thirsty animals to sound stimulus while drinking (5 trials) and while at rest (5 trials) were also tested. 1. Simple orienting respons to sound stimulus tended to occur more often and its duration tended to be shorter in the mammillary body group than in the operated control group. 2. With repetition of trials, the occurrence of orienting response in each trial decreased progressively in both groups (habituation). However, the rate of habituation was significantly less prominent in the mammillary body group than in the operated control group. 3. Under attention·shift situation, orienting response tended to occur less often and its duration tended to be shorter in the mammillary body group than in the operated control group. 4. Orienting response to sound stimulus while drinking to quench thirst tended to occur more often and its duration tended to be shorter in the mammillary body group than in the operated control group. In quiet state, however, there existed no group difference with regard to the occurrence and duration of the orienting response. Although no obvious inference can be drawn from the above results, they may suggest the mammillary bodies being involved in the orienting response as a control mechanism inhibitory to the occurrence and facilitatory to the habituation of the response.

• 한국건축시공학회지
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• 제15권1호
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• pp.123-131
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• 2015

본 연구의 목적은 공동주택에서 발생하는 실내 외 생활소음원들의 종류를 파악하고, 발생 빈도가 높거나 소음레벨이 높은 특정 소음원을 선정하여 소음원별 발생 실태 및 특성을 분석하는 것이다. 공동주택 생활 소음원 실태 조사를 통해 24개의 생활 소음원을 도출하였으며, 그 중 소음의 발생 빈도 및 소음레벨이 높은 소음원 10개를 선정하여 실태조사 분석을 수행하였다. 연구 결과, 생활 소음원 10개 모두 시간대별 소음 발생 특징이 다르게 나타났다. 따라서 생활 소음 저감을 위해서는 소음원별 소음레벨이 크거나 발생빈도가 높은 시간대를 중심으로 강화된 법적 소음 기준 및 소음원별 발생 특성에 관한 거주자 대상의 교육 시행이 필요할 것이다.

• 터널과지하공간
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• 제25권6호
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• pp.534-542
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• 2015

대심도 시추공사는 시추비트의 마모로 인해 발생하는 라운드트립(round trip)이 이산적으로 발생된다. 라운드트립은 심도가 깊어질수록 교체에 소요되는 시간이 증가하여 공사 성능에 많은 영향을 끼친다. 따라서 시추 프로젝트의 타당성분석 및 관리 효율화를 위해서는 라운드트립의 신뢰적인 예측기술이 확보되어야 한다. 이승수 등(2013)은 TOSA(round trip occurrence simulation algorithm)을 제시하여 비트의 마모단계별 라운드트립이 발생되는 깊이와 시점을 분석할 수 있는 알고리즘을 제시하였다. 그러나 시뮬레이션 구간의 수가 증가할수록 시뮬레이션 횟수가 기하급수적으로 증가하여 연산시간이 오래 걸린다는 단점을 가지고 있다. 본 연구에서는 유전자 알고리즘을 활용하여 단 시간에 TOSA를 통한 최적화된 라운드트립의 발생을 예측할 수 있는 모듈을 개발하고 검증한 내용에 대하여 소개한다.

• 한국환경과학회지
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• 제6권2호
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• pp.95-106
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• 1997

The characteristics on the transtion probabilities and periodicity for the daily precipitation occurrence in Korean peninsula are investigated by applying the Markov chain properties to daily precipitation occurrence. In order to examine the responses of Markov Chain properties to the applied period and their magnitudes, three cases (Case A: 1956~ 1985 at 14 stations, Case B: 1965~ 1994 at 14 stations, and Case C: 1985~ 1994 at 63 stations) are considered In this study. The transition probabilities from wet day to wet day for all cases are about 0.50 and in summer, especially July, are higher. In addition, considering them in each station we can find that they are the highest at Ullung-do and lowest at Inchon for all cases. The annual equilibrium probabilities of a wet day appear 0.31 In Case A, 0.30 Case B, and 0. 29 Case C, respectively. This may explain that as the data-period used becomes shorter, the higher the equilibrium probability is. The seasonal distributions of equilibrium probabilities are appeared the lowest(0.23~0.28) in winter and the highest(more than 0.39) in spring and monthly in .truly and in October, repectively. The annual mean wet duration for all cases is 2.04 days in Case A, 1.99 Case B, and 1.89 Case C, repectively. The weather cycle obtained from the annual mean wet and dry duration is 6.54~6.59 days, which are closely associated with the movement of synoptic systems. And the statistical tests show that the transitions of daily precipitation occurrence for all cases may have two-state first Markov chain property, being the stationarity in time and heterogeneity in space.

• BMB Reports
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• 제40권2호
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• pp.172-179
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• 2007

PCR-mediated recombination describes the process of in vitro chimera formation from related template sequences present in a single PCR amplification. The high levels of genetic redundancy in eukaryotic genomes should make recombination artifacts occur readily. However, few evolutionary biologists adequately consider this phenomenon when studying gene lineages. The cytosolic glyceraldehyde-3-phosphate dehydrogenase gene (GapC), which encodes a NADP-dependent nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase in the cytosol, is a classical lowcopy nuclear gene marker and is commonly used in molecular evolutionary studies. Here, we report on the occurrence of PCR-mediated recombination in the GapC gene family of Hibiscus tiliaceus. The study suggests that recombinant areas appear to be correlated with DNA template secondary structures. Our observations highlight that recombination artifacts should be considered when studying specific and allelic phylogenies. The authors suggest that nested PCR be used to suppress PCRmediated recombination.

• 성인간호학회지
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• 제16권3호
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• pp.452-459
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• 2004

Purpose: To investigate the effect of oral care either with normal saline or with tantum solution on the oral state of the patients in intensive care unit as well as the frequency of bacteria occurrence inside their oral cavities. Method: The study was performed from March thru May of 2003 on the nonequivalent control group non-synchronized quasi-experimental design. Forty subjects were selected for each group. The data were analyzed using the SPSS 10.0 Win. The pre-experimental homogeneity and post-experimental differences between the two groups were analyzed with t-test. Result: There was a significant difference in the oral cavity state between the experimental group that had used normal saline and the control group that had used tantum solution. Conclusion: Based on the results described above, it is considered that normal saline is more effective than the tantum solution for the oral care of the patients in intensive care unit.

• 한국산학기술학회논문지
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• 제11권1호
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• pp.130-140
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• 2010

SIP(Session Initiation Protocol)는 IP 기반의 VoIP(Voice over IP) 서비스를 실현하기 위한 시그널링 프로토콜이다. 그러나 SIP 프로토콜은 기존의 IP 망을 활용하기 때문에 많은 보안 취약점이 존재한다. 특히 SIP 헤더의 정보를 변경하여 전송하는 SIP Malformed 메시지 공격 같은 경우 VoIP 서비스의 오작동을 유발하거나, 악성코드를 삽입하여 SIP 클라이언트 시스템내 개인정보를 유출하는 등 심각한 문제점을 보이고 있어 이에 대한 대체 방안이 제시되어야 한다. 이에 본 논문에서는 SIP Malformed 메시지 공격탐지에 대한 기존의 연구를 분석하고, 언어 처리에서 단어의 연관성을 분석하는 기법으로 사용되는 공기 정보(Co-occurrence Information)와 네트워크에서 발생하는 실제 SIP 세션 상태 정보를 반영하여 SIP 연관규칙 패턴을 생성하는 기법을 제안하였다. 본 논문에서 제안한 공기정보 기반 SIP 연관규칙 패턴을 이용하여 SIP 비정상메시지 공격을 탐지한 결과 평균 87%의 탐지율을 보였다.

• Journal of Microbiology and Biotechnology
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• 제26권5호
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• pp.928-937
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• 2016

S-Nitrosoglutathione reductase (GSNOR) metabolizes S-nitrosoglutathione (GSNO) and has been shown to play important roles in regulating cellular signaling and formulating host defense by modulating intracellular nitric oxide levels. The enzyme has been found in bacterial, yeast, mushroom, plant, and mammalian cells. However, to date, there is still no evidence of its occurrence in filamentous fungi. In this study, we cloned and investigated a GSNOR-like enzyme from the filamentous fungus Aspergillus nidulans. The enzyme occurred in native form as a homodimer and exhibited low thermal stability. GSNO was an ideal substrate for the enzyme. The apparent K_m and k_cat values were 0.55 mM and 34,100 min^-1, respectively. Substrate binding sites and catalytic center amino acid residues based on those from known GSNORs were conserved in this enzyme, and the corresponding roles were verified using site-directed mutagenesis. Therefore, we demonstrated the presence of GSNOR in a filamentous fungus for the first time.