• Journal of Genetic Medicine
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• v.11 no.2
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• pp.43-48
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• 2014

Chorionic villus sampling has gained importance as a tool for early cytogenetic diagnosis with a shift toward first trimester screening. First trimester screening using nuchal translucency and biomarkers is effective for screening. Chorionic villus sampling generally is performed at 10-12 weeks by either the transcervical or transabdominal approach. There are two methods of analysis; the direct method and the culture method. While the direct method may prevent maternal cell contamination, the culture method may be more representative of the true fetal karyotype. There is a concern for mosaicism which occurs in approximately 1% of cases, and mosaic results require genetic counseling and follow-up amniocentesis or fetal blood sampling. In terms of complications, procedure-related pregnancy loss rates may be the same as those for amniocentesis when undertaken in experienced centers. When the procedure is performed after 9 weeks gestation, the risk of limb reduction is not greater than the risk in the general population. At present, chorionic villus sampling is the gold standard method for early fetal karyotyping; however, we anticipate that improvements in noninvasive prenatal testing methods, such as cell free fetal DNA testing, will reduce the need for invasive procedures in the near future.

• Journal of Veterinary Science
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• v.24 no.3
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• pp.40.1-40.6
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• 2023

Analysis of the VP1 gene sequence of the foot and mouth disease virus (FMDV) is critical to understanding viral evolution and disease epidemiology. A standard set of primers have been used for the detection and sequence analysis of the VP1 gene of FMDV directly from suspected clinical samples with limited success. The study validated VP1-specific degenerate primer-based reverse transcription polymerase chain reaction (RT-PCR) for the qualitative detection and sequencing of serotype O FMDV lineages circulating in India. The novel degenerate primer-based RT-PCR amplifying the VP1 gene can circumvent the genetic heterogeneity observed in viruses after cell culture adaptation and facilitate precise viral gene sequence analysis from clinical samples.

• Journal of Korean Physical Therapy Science
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• v.10 no.1
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• pp.212-221
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• 2003

To observe the anatomical structures which cause a cervicogenic headache it reports, from viewpoint of physical therapist in treatment multiple to observe method which approaches, the reporter it does. With the manipulation the vertebral manipulation effected an affirmative effect to cervicogenic headache(Niels Nilsson et al,1997). The manipulation, soft the tissue massage, postural education/advice, muscular elongation, the traction, and postural exercises initially came to be used with that technique which the upper cervical vertebra(0-C3) passive accessory intervertebral movement comes to be used with a cervicogenic headache treatment technique(Grant T & Niere K., 2000). Also, it relates with the diagnosis standard about a cervicogenic headache when the body function over of the cervical vertebra is discovered, the Muscle energy technique was proposed in the treatment which is safety and effect(Bogduk N,2001). The TENS and the Mange gave a reduction effect of pain often.

• Journal of International Society for Simulation Surgery
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• v.2 no.1
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• pp.40-42
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• 2015

Purpose Usability is an important factor in our life. This paper presents an approach to design the clinical work-flow for ultrasound system. And, we tried to apply this work-flow in diagnosis ultrasound system. Materials and Methods For user learnability, we follow international standard IEC 60601-1-1 and IEC 62366 which describes usability of medical instrument. User requirement are applied by 10 clinicians who are well aware of usability. We considered user environment and designed clinical work-flow into two types: general use and emergency use. The designed clinical work-flow was evaluated by 10 clinicians and results derived from the evaluation were analyzed. Results We could successfully design optimized clinical workflow of ultrasound system. Conclusion This paper suggests usability testing for optimized ultrasound clinical workflow. Using this clinical work flow, users can enhance their clinical performance and reduce operation time.

• Proceedings of the KIEE Conference
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• 2000.07b
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• pp.726-728
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• 2000

In this paper, after considering the standard data that are obtained by the study of the dynamic and mechanical characteristics (such as the torque characteristics and the force distribution analysis of the wobble motor), we design the prototype of the magnetostatic wobble motor. It can be applied to the high-precision medical instruments such as the ultrasonic catheter for the diagnosis and treatment of vascular disease.

• Journal of Interdisciplinary Genomics
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• v.6 no.1
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• pp.1-5
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• 2024

Chromosome 22 is an acrocentric chromosome containing 500-600 genes, representing 1.5%-2% of the total DNA in cells. It was the first human chromosome to be fully sequenced by the Human Genome Project. Several syndromes involving the partial deletion or duplication of chromosome 22 are well descibed, including 22q11.2 deletion syndrome, 22q11.2 duplication syndrome, 22q11.2 distal deletion syndrome, Phelan-McDermid syndrome caused by a 22q13 deletion or pathogenic variant in SHANK3, and cat-eye syndrome caused by a 22 pter-q11 duplication. This review aims to provide concise information on the clinical characteristics of these syndromes. In particular, the similarities in features among these syndromes, genetic basis, and standard detection techniques are described, providing guidance for diagnosis and genetic counselling.

• Proceedings of the Korean Geotechical Society Conference
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• 2003.06a
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• pp.3.1-11
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• 2003

Recently the problems related to the failure of the retaining wall structure has become great concern since the damage to the properties and human losses have occurred in the rainy season. However, a detail guideline on safety inspection and appropriate diagnosis on the retaining wall structure have not yet proposed and therefore, the inspection process and results are mainly dependant upon the engineers. The objective of this study is to propose objective and quantitative evaluation method for the condition based on the damage shapes and material types. In this purpose, composing materials of retaining wall are divided Into concrete, gabion, stone and reinforced earth, and then the evaluation items and method are suggested on the basis of the materials and structural characteristics of the retaining wall.

• Proceedings of the KSPS conference
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• 2002.11a
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• pp.141-144
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• 2002

The relations between words intelligibility and sentences intelligibility were tested on adults with cerebral palsy(athetoid type). Intelligibility is used as an important evaluation value in the field of diagnosis and therapy of dysarthric patients. In order to develop one syllable phonetic contrast intelligibility test using specific phonetic contrasts, the correlation with sentences intelligibility was tested to find out the validity. Pearson's simple correlation coefficient was .83 that shows a high correlation. Also, comparing the range and standard deviation given by seven evaluators on each subject, it was shown that when evaluating patients of moderate intelligibility, words intelligibility was more reliable than sentences intelligibility.

• Journal of Environmental Health Sciences
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• v.4 no.1
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• pp.23-25
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• 1977

Transaminase has been a popular methods in the clinical laboratory for the diagnosis of particular diseases. The methods we are familiar with should be considered further on the serum states provided on the test to be done. (serum freshness, temperature and duration preserved) I have studied transaminase activities of the serum preserved under frozen (-10$\circ$C), refrigerated (4$\circ$C) and room temperature conditions. At a given interval those activities of serum are measured and then the results are compared with the optical density and calculated for the standard deviation and percent variation (Table 1. & Fig. 1.) G.O.T. activity is maintained decreased at a relatively constant rate from 2nd day to 14th day preservation under frozen and refrigerated but its activity variation at 25$\circ$C are far greater than the above conditions throughout the test periods. Elevated G.P.T. level of serum compared with G.O.T. are remained at any temperature and duration. Unless the determination of amino acid level study can not ruled out clearly.

• Proceedings of the KIEE Conference
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• 2006.05a
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• pp.78-82
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• 2006

The Partial Discharge Monitoring System is technology which is available to measure & analysis the partial discharge of Power equipment. This technology is in the limelight as a pre-forecast system of equipment defect but there are some problems like no protocol standard, layered network management and the limitation of physical size. This paper presents whole system structure includes engineering centers, LN(Logical Node) to apply PDMS for, base-digital substation system, ICE61850 compatible Condition Monitoring &Diagnosis (CMD), Local Unit(LU), Intelligent Electronic Device (IED) for the solution scheme of these limitations.