• Journal of Pharmaceutical Investigation
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• 제33권3호
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• pp.245-253
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• 2003

Dissolution profile comparsions can be done by virtue of the similarity factor $(f_2)$. It is a logarithmic reciprocal square root transformation of the sum of squared error of % dissolution differences between two profiles at several time points. It gives information on the degree of similarity between the two profiles: An $f_2$ value between 50 and 100 suggests the similarity/equivalence of the two dissolution curves being compared. The objective of this report was to provide a careful examination on the $f_2$ metrics in detail. It was shown that $f_2$ values exceeded 50, when relative differences in % dissolved between two products were less than 15% at all time points. The similarity factor value was also found to be greater than 50, in cases when absolute % dissolution differences were below 10% at all time points. Interestingly, the $f_2$ value was changed by the number of the time points selected for calculation. In particular, $f_2$ tended to have higher values, when the $f_2$ metrics used a large number of time points in which % dissolved reached plateau. Finally, since the similarity factor was a sample statistics, it was impossible to infer type I/II errors and sampling error. Despite certain limitations inherited in the $f_2$ metrics, it was easy and convenient to evaluate how similar the two dissolution profiles were.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제11권12호
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• pp.5855-5877
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• 2017

In view of personal health and disease management based on cost effective healthcare services, there is a growing need for real-time monitoring services. The electrocardiogram (ECG) signal is one of the most important of health information and real-time monitoring of the ECG can provide an efficient way to cope with emergency situations, as well as assist in everyday health care. In this system, it is essential to continuously collect and transmit large amount of ECG data within a given time and provide maximum user convenience at the same time. When considering limited wireless capacity and unstable channel conditions, appropriate signal processing and transmission techniques such as compression are required. However, ISO/IEEE 11073 standards for interoperability between personal health devices cannot properly support compressed data transmission. Therefore, in the present study, the problems for handling compressed data are specified and new extended agent and manager are proposed to address the problems while maintaining compatibility with existing devices. Extended devices have two PM-stores enabling compression and a novel transmission scheme. A variety of compression techniques can be applied; in this paper, discrete cosine transformation (DCT) is used. And the priority of information after DCT compression enables new transmission techniques for performance improvement. The performance of the compressed signal and the original uncompressed signal transmitted over the noisy channel are compared in terms of percent root mean square difference (PRD) using our simulation results. Our transmission scheme shows a better performance and complies with 11073 standards.

• 대한임상전기생리학회지
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• 제8권2호
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• pp.33-37
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• 2010

Purpose : We investigated the effects of the insole types on lower leg muscle activation during treadmill walking. The three insole types investigated for this study were normal insole, medial wedge insole, and viscoheel. Methods : Participants were assigned into three groups. People with foot transformation were excluded from this study. Each participant walked for ten minutes. The first day we applied a normal insole. On the second day, a medial wedge insole was applied. Finally, on the last day a viscoheel was applied. After walking on a treadmill for ten minutes, we measured muscle activation in lower leg muscles (gastrocnemius and tibialis anterior). Surface electromyography (EMG) was used to measure muscle activity. The data were analyzed using one-way analysis of variance (ANOVA) with repeated measures to determine the statistical significance. Results : The results of this study were summarized as follows. While walking on the treadmill, root mean square (RMS) values of the gastrocnemius when the viscoheel was applied were significantly lower than the other insole types. There was no significant difference for the RMS values for the tibialis anterior using viscoheel. The normal insole and viscoheel insole were significantly different in a post hoc analysis. However, there was no significant difference for normal insole and medial wedge insole. Conclusion : Using a viscoheel insole decreases muscle activity of the lower leg. Therefore, in conclusion, the viscoheel insole type reduces the load on the lower leg during walking.

• Smart Structures and Systems
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• 제25권1호
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• pp.65-80
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• 2020

In order to protect a structure over its full life cycle, a novel tuned mass damper (TMD), the so-called semi-active eddy current pendulum tuned mass damper (SAEC-PTMD), which can retune its frequency and damping ratio in real-time, is proposed in this study. The structural instantaneous frequency is identified through a Hilbert-Huang transformation (HHT), and the SAEC-PTMD pendulum is adjusted through an HHT-based control algorithm. The eddy current damping parameters are discussed, and the relationship between effective damping coefficients and air gaps is fitted through a polynomial function. The semi-active eddy current damping can be adjusted in real-time by adjusting the air gap based on the linear-quadratic-Gaussian (LQG)-based control algorithm. To verify the vibration control effect of the SAEC-PTMD, an idealized linear primary structure equipped with an SAEC-PTMD excited by harmonic excitations and near-fault pulse-like earthquake excitations is proposed as one of the two case studies. Under strong earthquakes, structures may go into the nonlinear state, while the Bouc-Wen model has a wild application in simulating the hysteretic characteristic. Therefore, in the other case study, a nonlinear primary structure based on the Bouc-Wen model is proposed. An optimal passive TMD is used for comparison and the detuning effect, which results from the cumulative damage to primary structures, is considered. The maximum and root-mean-square (RMS) values of structural acceleration and displacement time history response, structural acceleration, and displacement response spectra are used as evaluation indices. Power analyses for one earthquake excitation are presented as an example to further study the energy dissipation effect of an SAECPTMD. The results indicate that an SAEC-PTMD performs better than an optimized passive TMD, both before and after damage occurs to the primary structure.

• 한국지형학회지
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• 제23권3호
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• pp.105-122
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• 2016

To evaluate the changes in the physical characteristics of open rainfall related to canopy effects and rainfall intensity in Korea, the terminal velocity of raindrops and drop size distributions(DSD) were continuously measured by an optical-laser disdrometer in an open site(Op) and in two forest stands(Th1: Larix leptolepis, Th2: Pinus koraiensis) during five rainfall events in 2008. The terminal velocity, DSD and two forms of kinetic energy(KE, $Jm^{-2}$ $mm^{-1}$; KER, $Jm^{-2}$ $h^{-1}$) of open rainfall drops were determined and were compared with those of throughfall drops under two different canopy heights. The effects of the canopy and rainfall intensity, together with wind speed, on the changes in drop size and kinetic energy of throughfall were evaluated. Throughfall drops were larger than open rainfall drops. The distribution of terminal velocities for the drop sizes measured at Th2 was lower than that at Op; however, at Th1 the distribution was similar to that at Op. The total kinetic energy of throughfall at Th1 and Th2 was higher than the total kinetic energy of open rainfall, and the kinetic energy distribution for the drop sizes wassimilar to the drop size distribution. The observed throughfall-KER at Th1 was lower than an estimate previously produced using a model. The overestimation from the modeled value at Th1 was likely to be due to overestimated values of a square root transformation of fall height and its coefficient in the model because the distributions of terminal velocity for the drop size measured at Th1 were similar to those of open rainfall.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2022년도 학술발표회
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• pp.141-141
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• 2022

Drought is a global phenomenon that affects almost all landscapes and causes major damages. Due to non-linear nature of contributing factors, drought occurrence and its severity is characterized as stochastic in nature. Early warning of impending drought can aid in the development of drought mitigation strategies and measures. Thus, drought forecasting is crucial in the planning and management of water resource systems. The primary objective of this study is to make improvement is existing drought forecasting techniques. Therefore, we proposed an improved version of Seasonal Autoregressive Integrated Moving Average (SARIMA) model (MD-SARIMA) for reliable drought forecasting with three years lead time. In this study, we selected four watersheds of Han River basin in South Korea to validate the performance of MD-SARIMA model. The meteorological data from 8 rain gauge stations were collected for the period 1973-2016 and converted into watershed scale using Thiessen's polygon method. The Standardized Precipitation Index (SPI) was employed to represent the meteorological drought at seasonal (3-month) time scale. The performance of MD-SARIMA model was compared with existing models such as Seasonal Naive Bayes (SNB) model, Exponential Smoothing (ES) model, Trigonometric seasonality, Box-Cox transformation, ARMA errors, Trend and Seasonal components (TBATS) model, and SARIMA model. The results showed that all the models were able to forecast drought, but the performance of MD-SARIMA was robust then other statistical models with Wilmott Index (WI) = 0.86, Mean Absolute Error (MAE) = 0.66, and Root mean square error (RMSE) = 0.80 for 36 months lead time forecast. The outcomes of this study indicated that the MD-SARIMA model can be utilized for drought forecasting.

• 한국전산구조공학회논문집
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• 제36권6호
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• pp.415-421
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• 2023

본 논문에서는 시멘트에 탄소나노튜브를 혼입하여 전기 전도성을 향상시킨 복합재료의 압저항 특성을 딥러닝 기반 트랜스포머 알고리즘을 적용하여 분석하였다. 훈련 데이터 확보를 위한 실험수행을 병행하였으며, 기존 연구문헌을 참조하여 배합설정, 시편제작, 화학조성 분석, 압저항 성능측정 실험을 수행하였다. 특히 본 연구에서는 탄소나노튜브 혼입 시편뿐 아니라 플라이애시를 바인더 대비 50% 대체한 시편에 대한 제작 및 성능평가를 함께 수행하여, 전도성 시멘트 복합재료의 압저항 특성 향상 가능성을 탐구하였다. 실험결과, 플라이애시 대체 바인더의 경우 보다 안정적인 압저항 특성결과가 관찰되었으며, 측정된 데이터의 80%를 이용하여 트랜스포머 모델을 훈련시키고 나머지 20%를 통해 검증하였다. 해석 결과는 실험적 측정과 대체로 부합하였으며, 평균 절대 오차 및 평균 제곱근 오차는 각각 0.069~0.074와 0.124~0.132을 나타내었다.

• 대한원격탐사학회지
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• 제40권3호
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• pp.257-268
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• 2024

Drone-mounted hyperspectral sensors (DHSs) have revolutionized remote sensing in agriculture by offering a cost-effective and flexible platform for high-resolution spectral data acquisition. Their ability to capture data at low altitudes minimizes atmospheric interference, enhancing their utility in agricultural monitoring and management. This study focused on addressing the challenges of radiometric and geometric distortions in preprocessing drone-acquired hyperspectral data. Radiometric correction, using the empirical line method (ELM) and spectral reference panels, effectively removed sensor noise and variations in solar irradiance, resulting in accurate surface reflectance values. Notably, the ELM correction improved reflectance for measured reference panels by 5-55%, resulting in a more uniform spectral profile across wavelengths, further validated by high correlations (0.97-0.99), despite minor deviations observed at specific wavelengths for some reflectors. Geometric correction, utilizing a rubber sheet transformation with ground control points, successfully rectified distortions caused by sensor orientation and flight path variations, ensuring accurate spatial representation within the image. The effectiveness of geometric correction was assessed using root mean square error(RMSE) analysis, revealing minimal errors in both east-west(0.00 to 0.081 m) and north-south directions(0.00 to 0.076 m).The overall position RMSE of 0.031 meters across 100 points demonstrates high geometric accuracy, exceeding industry standards. Additionally, image mosaicking was performed to create a comprehensive representation of the study area. These results demonstrate the effectiveness of the applied preprocessing techniques and highlight the potential of DHSs for precise crop health monitoring and management in smart agriculture. However, further research is needed to address challenges related to data dimensionality, sensor calibration, and reference data availability, as well as exploring alternative correction methods and evaluating their performance in diverse environmental conditions to enhance the robustness and applicability of hyperspectral data processing in agriculture.

• 대한원격탐사학회지
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• 제37권2호
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• pp.221-232
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• 2021

본 연구는 KOMPSAT-3 및 KOMPSAT-3A호에서 전처리 단계에 따라 구분하여 제공하는 Level 1R 영상과 Level 1G 영상을 이용하여 기준영상의 기하품질에 따른 상호좌표등록 결과 분석을 수행하였다. 기준영상으로 Level 1R 영상 및 1G 영상 각각을 사용하고 대상영상은 Level 1R 영상을 사용하여 상호좌표등록을 수행하였다. 실험을 위해 대전지역에서 촬영된 KOMPSAT-3 및 3A호의 Level 1R, 1G 영상 총 7장을 이용하였다. 상호좌표등록을 수행하기 위해, 우선적으로 특징기반 정합기법인 SURF (Speeded-Up Robust Feature) 기법과 영역기반 정합기법인 위상상관 (Phase Correlation) 기법을 함께 이용한 반복적 정합기법을 통해 두 영상의 기하학적 위치를 개략적으로 일치시켜 주었다. 개략적으로 일치된 영상에서 SURF 기법을 이용하여 정합쌍을 추출하고 Affine 변환모델과 Piecewise Linear 변환모델을 각각 구성하여 상호좌표등록을 수행하였다. 실험결과, 기하오차가 보정된 Level 1G 영상을 기준영상으로 선정하였을 경우, Level 1R 영상을 이용하였을 때보다 상대적으로 많은 수의 정합쌍을 추출하였다. 또한, 기준영상이 Level 1G 영상일 때의 상호좌표등록 RMSE (Root Mean Square Error) 값이 평균 5화소 미만으로 Level 1R 영상을 이용하였을 때보다 더 낮은 것을 확인하였다. 이는 상호좌표등록 수행 시 두 위성영상 간의 초기위치관계가 상호좌표등록 결과에 영향을 끼칠 수 있음을 의미하며, 기준영상의 기하품질이 우수할수록 안정적인 상호좌표등록 정확도를 나타내는 것을 확인하였다.

• 한국근적외분광분석학회:학술대회논문집
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• 한국근적외분광분석학회 2001년도 NIR-2001
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• pp.2111-2111
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• 2001

A chemoinfometrical method for evaluating the quantitative determination of crystallinity one polymorphs based on fourie-transformed near-infrared (FT-NIR) spectroscopy was established. A direct comparison of the data with the ones collected from using the and compared with the conventional powder X-ray diffraction method was performed. [Method] The pPure a and g forms of indomethacin (IMC) were prepared by reportedusing published methods. Six kinds of standard samples obtained by physically mixing of a and g forms. After the powder X-ray diffraction profiles of samples have been measured, the intensity values were normalized to against the intensity of silicon powder as the as an external standard. The calibration curves for quantification of crystal content were based upon the total relative intensity of four diffraction peaks from of the form g crystal. FT-NIR spectra of six calibration sample sets were recorded 5 times with the NIR spectrometer (BRAN+LUEBBE). Chemoinfometric analysis was performed on the NIR spectral data sets by applying the principal component regression (PCR). [Results] The relation between the actual and predicted polymorphic contents of form g IMC measured using by the X-ray diffraction method shows a good straight linen linear relation., and it has slope of 0.023, an intercept of 0.131 and a correlation coefficient of 0.986. PCR analyses wereis was performed based on normalized NIR spectra sets offer standard samples of known content of IMC g form. IMC. A calibration equation was determined to minimize the root mean square error of the predictionthe prediction. Figure 1 shows a plot of the calibration data obtained by NIR method between the actual and predicted contents of form g IMC. The predicted values were reproducible and had a smaller standard deviation. Figure 2 shows that the plot for the predicted transformation rate (%) of form a IMC to form g as measured by X-ray diffractomeoy against to those as measured by NIR method. The plot has a slope of 1.296, an intercept of 1,109, and a correlation coefficient of 0.992. The line represents a satisfactory correlation between the two predicted values of form g IMC content. Thus NIR spectroscopy is an effective method for the evaluation to the pharmaceutical products of quantitative of polymorph.