• 한국정보전자통신기술학회논문지
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• 제15권6호
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• pp.492-505
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• 2022

본 연구는 IoT 센싱 데이터의 무 손실 실시간 전송에 활용 가능한 BL-beta 코드의 엔코딩 및 디코딩 성능 개선을 통해 효과적으로 압축 데이터를 실시간으로 전송하고, 해독할 수 있도록 로직을 개선한 결과에 대한 연구이다. BL-beta 코드의 엔코딩 과정에는 비교적 연산 부담이 큰 로그 함수와 지수 함수, 나눗셈 및 제곱근 연산 등이 포함되어 있는데 이를 개선하여 비트 연산과 이진수 패턴 분석 그리고 비트 패턴을 이용한 뉴턴-랩슨 방법의 초기 값 설정을 통해 빠르게 데이터를 BL-beta 코드로 엔코딩 및 디코딩 할 수 있는 새로운 규칙성을 발견하였으며 이를 적용하여 기존 연구와 비교하여 알고리즘의 엔코딩 속도를 평균 24.8%, 디코딩 속도를 평균 5.3% 개선하였다.

• 한국식품위생안전성학회지
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• 제28권3호
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• pp.217-221
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• 2013

본 연구는 가공치즈에서 Staphylococcus aureus의 생장을 예측하기 위한 수학적 모델을 개발하였다. 모짜렐라 슬라이스 치즈와 체다 슬라이스 치즈에 S. aureus 혼합균액(ATCC13565, ATCC14458, ATCC23235, ATCC27664, NCCP10826) 0.1 ml (log CFU/g)을 접종한 후 $4^{\circ}C$ (1440 h), $15^{\circ}C$ (288 h), $25^{\circ}C$ (72 h), and $30^{\circ}C$ (48 h)에 저장하면서 총 세균수와 S. aureus 세균수를 tryptic soy agar와 mannitol salt agar를 이용해 각각 확인하였다. S. aureus의 세균 수를 Baranyi model로 분석하여 생장률(${\mu}_{max}$; ${\log}CFU{\cdot}g^{-1}{\cdot}h^{-1}$), 유도기(LPD; h), 초기 세균 수(log CFU/g), 최대 생장 세균수(log CFU/g)를 계산함으로써 1차 모델을 개발하였다. 또한 저장온도와 S. aureus의 ${\mu}_{max}$, LPD의 관계를 분석하기 위해 square root model과 exponential decay model을 이용하였고 이를 통해 2차모델을 개발하였으며 개발된 모델의 평균제곱근 편차(RMSE)를 계산하여 적합성을 검증하였다. $4^{\circ}C$에서는 모든 가공치즈에서 황색포도상구균의 생장이 관찰되지 않았으나 $15^{\circ}C$, $25^{\circ}C$, $30^{\circ}C$에서는 모짜렐라 슬라이스와 체다 슬라이스 치즈에서 황색포도상구균이 생장하였으며($R^2=0.785-0.996$) 저장온도가 높아짐에 따라 생장률은 증가한 반면 유도기는 감소하였다($R^2=0.879-0.999$). 또한 개발된 모델의 RMSE 값은 0.3500-0.5344로 적합하였다. 따라서 본 연구결과는 가공치즈에서 황색포도상구균의 생장 예측에 유용하게 사용될 것이다.

• 대한원격탐사학회지
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• 제30권2호
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• pp.315-329
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• 2014

서울을 포함한 수도권의 지표면 온도를 분석하기 위하여 Landsat과 MODIS의 지표면 온도, AWS의 기온, 지표면 고도 및 토지이용도를 이용하였다. Landsat과 MODIS 위성의 지표면 온도와 AWS 기온의 분석은 상관계수, 평방근 오차(Root Mean Squared Error, RMSE), 선형회귀분석 등의 통계분석방법을 적용하였다. Landsat과 MODIS 지표면 온도의 상관계수는 0.32이고 RMSE는 4.61 K였다. 그리고 Landsat과 MODIS 지표면 온도와 AWS 기온의 상관성은 각각 0.83과 0.96이며 RMSE는 3.28 K, 2.25 K이었다. Landsat과 MODIS 지표면 온도는 비교적 높은 상관성을 보였으나 각각의 선형회귀의 기울기는 0.45와 1.02이었다. Landsat 5의 경우 전체 관측소에 대하여 0.5이하의 낮은 상관성을 보였고 Landsat 8의 경우는 일치되는 지점이 다른 위성에 비하여 적었으나 0.5이상의 상관성을 나타냈다. Landsat 7은 대부분 0.8이상의 높은 상관성을 보였고 대체적으로 서울중심부에서 높은 상관성이 나타났다. 위성의 지표면 온도와 지표유형에 따른 AWS 기온사이의 상관성은 0.8이상의 높은 상관성을 보였다. Landsat 위성의 지표면 온도의 상관성은 0.84이었고 RMSE는 3.1 K이상이었으며 MODIS 위성의 상관계수는 0.96이상이고 RMSE는 2.6 K이하였다. 결과적으로 두 위성의 지표온도의 차이는 관측시각 차이에 의한 것으로 위성의 해상도에 따라 복사량을 탐지하는 지표면의 면적 차이에 의하여 발생되는 것으로 사료된다.

• The Journal of Korean Physical Therapy
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• 제20권3호
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• pp.9-18
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• 2008

Purpose: We determined the effect of global synkinesis(GS) on gait ability, muscle contraction, and central neuron action potentials in post-stroke hemiplegic subjects. Methods: Thirty hemiplegia patients were evaluated for walking ability, muscle contraction, central neuron action potential, and comparing differences between the H-GS(high-global synkinesis) group and L-GS(low-global synkinesis) group. To obtain the GS level, surface electromyography(EMG) data were digitized and processed to root mean square(RMS). Walking ability was tested with a modified motor assessment scale(MMAS), a 10 m walking test, timed up and go(TUG) test, and a Fugl-Meyer assessment(FMA). Muscle contraction ability was measured as maximal isometric contraction(MIC) peak, MIC slope, and MIC ramp up using mechanomyography(MMG). Central neuron action potential was measured as the H/Mmax ratio or V/Mmax ratio using EMG. The data were analyzed with t-tests to determine the statistical significance. Results: MMAS(p<0.01), 10 m walking velocity(p<0.01), TUG(p<0.01), FMA-HKA(Hip, Knee, Ankle)(p<0.05), FMA-coordination(p<0.05), MIC peak (p<0.05), MIC slope(p<0.01), and MIC ramp up(p<0.05) were significantly different between H-GS and L-GS, as was the V/Mmax ratio(p<0.05), but H/Mmax was not. Conclusion: Lower GS levels indicated better walking ability and motor function. Therefore, intervention programs should consider GS levels in gait training of chronic hemiplegia.

• 대한토목학회논문집
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• 제14권2호
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• pp.307-316
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• 1994

기상 자료 미계측 지점의 단기 강우 예보 모형을 개발하였다. 본 연구 모형은 강우 모의 모형, 기상학적 동질성, 그리고 기상 변수 예측 및 추정에 관한 몇 가지 가정을 전제로 하였으며 강우의 예보에는 칼만 필터 기법을 사용하였다. 기존 모형의 방정식은 수운적 크기 분포(HSD)가 강우 강도에 종속이므로 강우량에 대하여 비선형이다. 본 연구 모형의 방정식은 HSD를 구름층 저류량의 함수로 구성함으로써 강우량에 대하여 비선형이다. 본 연구 모형의 방정식은 HSD를 구름층 저류량의 함수로 구성함으로써 강우량에 대하여 선형화되었다. 또한 기상 입력 변수는 경험 모형에 의하여 예측되었다. 본 연구 모형을 대청댐 유형의 호우 사상에 적용하였다. 그 결과 예보 및 실측 강우 강도간의 평균 자승 오차는 0.30~1.01 mm/hr이었다. 이 결과로 미루어 볼 때, 본 연구 모형에 수반된 가정은 합리적이며 본 연구 모형은 기상 자료 미계측 지점에서 강우를 단기 예보하는데 유용하다고 판단된다.

• 대한한의학회지
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• 제35권4호
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• pp.24-35
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• 2014

Objectives: Although the autonomic nervous system (ANS) is thought to play an important role in treatment of obesity, no study has been conducted to investigate acupuncture's effects on this aspect of the ANS. This study aimed to describe the effects of acupuncture in the ANS by means of heart rate variability (HRV) analysis. Methods: A total of 46 obese women aged from 21 to 54 with body mass index ranging from 25.1 to $39.3kg/m^2$ were recruited and randomized into both the real acupuncture group (n=23) and sham acupuncture group (n=23). A total of 3 instances of HRV analysis were conducted before, during, and after treatment. Statistically significant differences between time and groups were analyzed using repeated measure analysis of variance. Results: All parameters of time domain analysis and frequency domain analysis except for the square root of the mean squared differences of successive normal sinus intervals (RMSSD) and very low frequency (VLF) showed significant differences between times. The mean of all R-R intervals (mean RR) showed significant level of interaction between time and group. Between groups, time domain analysis of standard deviation of the normal-to-normal intervals (SDNN), RMSSD and frequency domain analysis of total power (TP) and high frequency (HF) showed significant differences. Conclusions: The real acupuncture group showed deactivation of parasympathetic function and relative increase of sympathetic activity in obese subjects. Further studies are necessary to uncover the mechanisms of acupuncture in obesity treatment.

• Genomics & Informatics
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• 제13권1호
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• pp.15-24
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• 2015

Fatty acid synthase (FASN, EC 2.3.1.85), is a multi-enzyme dimer complex that plays a critical role in lipogenesis. This lipogenic enzyme has gained importance beyond its physiological role due to its implications in several clinical conditions-cancers, obesity, and diabetes. This has made FASN an attractive pharmacological target. Here, we have attempted to predict the theoretical models for the human enoyl reductase (ER) and ${\beta}$-ketoacyl reductase (KR) domains based on the porcine FASN crystal structure, which was the structurally closest template available at the time of this study. Comparative modeling methods were used for studying the structure-function relationships. Different validation studies revealed the predicted structures to be highly plausible. The respective substrates of ER and KR domains-namely, trans-butenoyl and ${\beta}$-ketobutyryl-were computationally docked into active sites using Glide in order to understand the probable binding mode. The molecular dynamics simulations of the apo and holo states of ER and KR showed stable backbone root mean square deviation trajectories with minimal deviation. Ramachandran plot analysis showed 96.0% of residues in the most favorable region for ER and 90.3% for the KR domain, respectively. Thus, the predicted models yielded significant insights into the substrate binding modes of the ER and KR catalytic domains and will aid in identifying novel chemical inhibitors of human FASN that target these domains.

• International Journal of Fuzzy Logic and Intelligent Systems
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• 제15권2호
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• pp.102-110
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• 2015

The main source of noise in computed tomography (CT) images is a quantum noise, which results from statistical fluctuations of X-ray quanta reaching the detector. This paper proposes a neural network (NN) based hybrid filter for removing quantum noise. The proposed filter consists of bilateral filters (BFs), a single or multiple neural edge enhancer(s) (NEE), and a neural filter (NF) to combine them. The BFs take into account the difference in value from the neighbors, to preserve edges while smoothing. The NEE is used to clearly enhance the desired edges from noisy images. The NF acts like a fusion operator, and attempts to construct an enhanced output image. Several measurements are used to evaluate the image quality, like the root mean square error (RMSE), the improvement in signal to noise ratio (ISNR), the standard deviation ratio (MSR), and the contrast to noise ratio (CNR). Also, the modulation transfer function (MTF) is used as a means of determining how well the edge structure is preserved. In terms of all those measurements and means, the proposed filter shows better performance than the guided filter, and the nonlocal means (NLM) filter. In addition, there is no severe restriction to select the number of inputs for the fusion operator differently from the neuro-fuzzy system. Therefore, without concerning too much about the filter selection for fusion, one could apply the proposed hybrid filter to various images with different modalities, once the corresponding noise characteristics are explored.

• 동의신경정신과학회지
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• 제13권1호
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• pp.19-37
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• 2002

Objectives : This study sought to define autonomic functional difference on heart rate variability between headache patients and normal subjects Methods : We determined, heart rate variability of 52 headache patients and 30 normal subjects by means of three time domain measures: Mean PR(mean pulse rate), SDNN(standard deviation of all normal R-R intervals), RMSSD(the square root of the mean of sum of the squares of differences between adjacent normal R-R intervals), and five frequency domain measures: TP(total power), VLF(very low frequency), LF(low frequency), HF(high frequency). Results : 1) RMSSD, TP, HF, HF Norm of HRV decreased with aging and LF Norm, LF/HF increased with aging in headache patients. 2) There was no significant differences between migraine and tention headache in any standard index of HRV, whereas, HRV of total headache patients were smaller than those of normal subjects. 3) In the gender comparison, SDNN, RMSSD, HF of tention headache patients were the smallest and then migraine patients, normal subjects in order with man, whereas, LF Norm, LF/HF of normal subjects were the smallest with man. RMSSD of migraine patients were the smallest and then tention headache patients, normal subjects in order with women. 4) In the term of history of headache patients, SDNN, RMSSD were getting lower as long term. 5) There was no significant differences of HRV in physical symptom of headache patients. Conclusions : All of these results show that standard index of HRV of headache patients were significantly different with normal subjects.

• 동의신경정신과학회지
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• 제19권3호
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• pp.45-54
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• 2008

Objective: To treat psychogenic headache patients, doctors have to amplify on the headache caused by emotional stress to patients, and assist the patients to cope with difficulties. So, we investigated HRV of the headache patients caused by Chiljungsang and would like to apply to the clinical treatment. Method: Our study measured time and frequency domain HRV indicies(5-min resting study) of 123 headache patients caused by emotional stress. Standardized tests of HRV allow a quantitative estimation of autonomic nervous system function. Results & Conclusions: 1. The study classed as aspects of the head pain showed the differences in RMS-SD(square root of mean squared difference of successive NN intervals) band, HF(high frequency) band significantly. 2. The male headache patients showed higher all the indicies except heart rate compared to the female patients, significantly in SDNN(standard deviation of NN interval), TP(total Power), HF band. 3. As the patients grow older, SDNN, RMS-SD band was lower and LF(low frequency) band, LF/HF ratio higher significantly. The beginning age lower, SDNN, RMS-SD band was higher significantly. The duration of the disease longer, LF band, LF/HF ratio was higher significantly.