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Collimator Selection in Nuclear Medicine Imaging Using I-123 Generated by Te-124 Reaction (Te-124 Target로 생산된 I-123 SPECT 영상에서의 조준기 선택)

  • Kim, Hee-Joung;Son, Hye-Kyung;Bong, Joung-Kyun;Nam, Ki-Pyo;Lee, Hee-Kyung
    • The Korean Journal of Nuclear Medicine
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    • v.30 no.3
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    • pp.372-378
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    • 1996
  • In the case of $^{123}I$ from the $^{124}Te$(p,2n)reaction, the radionuclidic impurity is the high-energy gamma-emitting $^{124}I$, which interferes greatly with nuclear medicine images. The choice of a collimator can affect the quality of clinical SPECT images of [I-123]MIBG, [I-123] ${\beta}$-CIT, or [I-123]IPT. The tradeoffs that two different collimators make among spatial resolution, sensitivity, and scatter were studied by imaging a line source at 5cm, 10cm, 15cm distance using a number of plexiglass sheets between source and collimator, petri dish, two-dimensional Hoffman brain phantom, Jaszczak phantom, and three-dimensional Hoffman brain phantom after filling with $^{123}I$. (FWHM, FWTM, Sensitivity) for low-energy ultrahigh-resolution parallel - hole (LEUHRP) collimator and medium- energy general - purpose (MEGP) collimator were measured as (9.27mm, 61.27mm, $129CPM/{\mu}Ci$) and (10.53mm, 23.17mm, $105CPM/{\mu}Ci$), respectively. The image quality of two-dimensional Hoffman brain phantom with LEUHRP looked better than the one with MEGP. However, the image quality of Jaszczak phantom and three-dimensional Hoffman brain phantom with LEUHRP looked much worse than the one with MEGP because of scatter contributions in three-dimensional imaging situation. The results suggest that the MEGP is preferable to LEUHRP for three-dimensional imaging studies of [I-123]MIBG, [I-123] ${\beta}$-CIT, or [I-123]IPT.

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Radiological Dose Analysis to the Public Resulting from the Operation of Daedeok Nuclear Facilities (대덕부지 원자력관련시설 운영에 따른 주민피폭선량 현황분석)

  • Jeong, Hae Sun;Kim, Eun Han;Jeong, Hyo Joon;Han, Moon Hee;Park, Mi Sun;Hwang, Won Tae
    • Journal of Radiation Protection and Research
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    • v.39 no.1
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    • pp.38-45
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    • 2014
  • This paper describes the results of assessment of radiological dose resulting from operation of the Daedeok nuclear facilities including the HANARO research reactor, which has been performed to assure whether or not to comply with the regulation standards of the radioactive effluents releases. Based on the meteorological data and the radiation source term, the maximum individual doses were evaluated from 2010 to 2012. The atmospheric dispersion and the deposition factors of gaseous effluents were calculated using the XOQDOQ computer code. ENDOS-G and ENDOS-L code systems were also used for maximum individual dose calculation from gaseous and liquid effluents, respectively. The results were compared with the regulation standards for the radioactive effluents presented by the Nuclear Safety and Security Commission (NSSC). The effective doses and the thyroid doses of the maximum individual were calculated at the maximum exposed point in the Daedeok site, and contributions of exposure pathways to the radiological doses resulting from gaseous and liquid radioactive effluents were evaluated at each facility of the Daedeok site. As a result, the maximum exposed age was analysed to be the child group, and the operation of HANARO research reactor had a major effect more than 90% on the individual doses. The main exposure pathways for gaseous radioactive effluent were from ingestion and inhalation. The effective doses and the thyroid doses were considerably influenced by tritium and iodine, respectively. The gaseous radioactive effluents contributed more than 90% on the total doses, whereas the contributions of the liquid radioactive effluents were relatively low. Consequently, the maximum individual dose due to radioactive effluents from the nuclear facilities within the Daedeok site were less than 3% of the regulation standard over 3 years; therefore, it can be concluded that radioactive effluents from the nuclear facilities were well managed, with the radiation-induced health detriment for residents around the site being negligible.

Origin and Source Appointment of Sedimentary Organic Matter in Marine Fish Cage Farms Using Carbon and Nitrogen Stable Isotopes (탄소 및 질소 안정동위원소를 활용한 어류 가두리 양식장 내 퇴적 유기물의 기원 및 기여도 평가)

  • Young-Shin Go;Dae-In Lee;Chung Sook Kim;Bo-Ram Sim;Hyung Chul Kim;Won-Chan Lee;Dong-Hun Lee
    • Korean Journal of Ecology and Environment
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    • v.55 no.2
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    • pp.99-110
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    • 2022
  • We investigated physicochemical properties and isotopic compositions of organic matter (δ13CTOC and δ 15NTN) in the old fish farming (OFF) site after the cessation of aquaculture farming. Based on this approach, our objective is to determine the organic matter origin and their relative contributions preserved at sediments of fish farming. Temporal and spatial distribution of particulate and sinking organic matter(OFF sites: 2.0 to 3.3 mg L-1 for particulate matter concentration, 18.8 to 246.6 g m-2 day-1 for sinking organic matter rate, control sites: 2.0 to 3.5 mg L-1 for particulate matter concentration, 25.5 to 129.4 g m-2 day-1 for sinking organic matter rate) between both sites showed significant difference along seasonal precipitations. In contrast to variations of δ13CTOC and δ15NTN values at water columns, these isotopic compositions (OFF sites: -21.5‰ to -20.4‰ for δ13 CTOC, 6.0‰ to 7.6‰ for δ15NTN, control sites: -21.6‰ to -21.0‰ for δ13CTOC, 6.6‰ to 8.0‰ for δ15NTN) investigated at sediments have distinctive isotopic patterns(p<0.05) for seawater-derived nitrogen sources, indicating the increased input of aquaculture-derived sources (e.g., fish fecal). With respect to past fish farming activities, representative sources(e.g., fish fecal and algae) between both sites showed significant difference (p<0.05), confirming predominant contribution (55.9±4.6%) of fish fecal within OFF sites. Thus, our results may determine specific controlling factor for sustainable use of fish farming sites by estimating the discriminative contributions of organic matter between both sites.

Development of Mobile Cloud Computing Client UI/UX based on Open Source SPICE (오픈소스 SPICE 기반의 모바일 클라우드 컴퓨팅 클라이언트 UI/UX 개발)

  • Jo, Seungwan;Oh, Hoon;Shim, Kyusung;Shim, Kyuhyun;Lee, Jongmyung;An, Beongku
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.8
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    • pp.85-92
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    • 2016
  • Mobile cloud computing (MCC) is not just extensions of cloud concepts into mobile environments, but the service technologies that all mobile devices including smartphone can use the desired services by using cloud technology without the constraints of time and space. Currently, a lot of works on mobile cloud computing have been actively researching, whereas user interfaces are not so much researched. The main features and contributions of this paper are as follows. First, develop UI considering UX that is different from conventional interfaces supported by SPICE. Second, combine two button interface into one button interface when keyboard is used in mobile cloud computing clients. Third, develop a mouse interface suitable for mobile cloud computing clients. Fourth, in mobile cloud computing client, solve a problem that the selection of button/files/folder has at the corner. Finally, in mobile cloud computing clients we change mouse scroll mapping functions from volume button to scroll interface in touch-screen. The results of performance evaluation shows that users can input easily with the increased and fixed mouse interface. Since shortcut keys instead of the complex button keys of keyboard are provided, the input with 3-6 steps is reduced into 1 step, which can simply support complex keys and mouse input for users.

G Protein-Coupled Receptor Signaling in Gastrointestinal Smooth Muscle

  • Sohn, Uy-Dong;Kim, Dong-Seok;Murthy, Karnam S.
    • The Korean Journal of Physiology and Pharmacology
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    • v.5 no.4
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    • pp.287-297
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    • 2001
  • Contraction of smooth muscle is initiated by an increase in cytosolic $Ca^{2+}$ leading to activation of $Ca^{2+}$/ calmodulin-dependnet myosin light chain (MLC) kinase and phosphorylation of MLC. The types of contraction and signaling mechanisms mediating contraction differ depending on the region. The involvement of these different mechanisms varies depending on the source of $Ca^{2+}$ and the kinetic of $Ca^{2+}$ mobilization. $Ca^{2+}$ mobilizing agonists stimulate different phospholipases $(PLC-{\beta},\;PLD\;and\;PLA_2)$ to generate one or more $Ca^{2+}$ mobilizing messengers $(IP_3\;and\;AA),$ and diacylglycerol (DAG), an activator of protein kinase C (PKC). The relative contributions of $PLC-{\beta},\;PLA_2$ and PLD to generate second messengers vary greatly between cells and types of contraction. In smooth muscle cell derived form the circular muscle layer of the intestine, preferential hydrolysis of $PIP_2$ and generation of $IP_3$ and $IP_3-dependent\;Ca^{2+}$ release initiate the contraction. In smooth muscle cells derived from longitudinal muscle layer of the intestine, preferential hydrolysis of PC by PLA2, generation of AA and AA-mediated $Ca^{2+}$ influx, cADP ribose formation and $Ca^{2+}-induced\;Ca^{2+}$ release initiate the contraction. Sustained contraction, however, in both cell types is mediated by $Ca^{2+}-independent$ mechanism involving activation of $PKC-{\varepsilon}$ by DAG derived form PLD. A functional linkage between $G_{13},$ RhoA, ROCK, $PKC-{\varepsilon},$ CPI-17 and MLC phosphorylation in sustained contraction has been implicated. Contraction of normal esophageal circular muscle (ESO) in response to acetylcholine (ACh) is linked to $M_2$ muscarinic receptors activating at least three intracellular phospholipases, i.e. phosphatidylcholine-specific phospholipase C (PC-PLC), phospholipase D (PLD) and the high molecular weight (85 kDa) cytosolic phospholipase $A_2\;(cPLA_2)$ to induce phosphatidylcholine (PC) metabolism, production of diacylglycerol (DAG) and arachidonic acid (AA), resulting in activation of a protein kinase C (PKC)-dependent pathway. In contrast, lower esophageal sphincter (LES) contraction induced by maximally effective doses of ACh is mediated by muscarinic $M_3$ receptors, linked to pertussis toxin-insensitive GTP-binding proteins of the $G_{q/11}$ type. They activate phospholipase C, which hydrolyzes phosphatidylinositol bisphosphate $(PIP_2),$ producing inositol 1, 4, 5-trisphosphate $(IP_3)$ and DAG. $IP_3$ causes release of intracellular $Ca^{2+}$ and formation of a $Ca^{2+}$-calmodulin complex, resulting in activation of myosin light chain kinase and contraction through a calmodulin-dependent pathway.

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Methane Gas Emission from an Artificial Reservoir under Asian Monsoon Climate Conditions, with a Focus on the Ebullition Pathway (아시아 몬순 기후지역에 위치한 대형 인공호에서 기포형태로의 메탄 (CH4) 가스 배출량)

  • Kim, Kiyong;Jung, Sungmin;Choi, Youngsoon;Peiffer, Stefan;Knorr, Klaus-Holger;Kim, Bomchul
    • Korean Journal of Ecology and Environment
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    • v.51 no.2
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    • pp.160-167
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    • 2018
  • The role played by reservoirs in the biogeochemical cycles of elements is a subject of ongoing debate. Recent research has revealed that reservoirs emit significant levels of greenhouse gases. To assess the importance of reservoirs in monsoon climate areas as a source of methane gas into the atmosphere, we investigated variations in organic carbon (OC) input into the reservoir, oxic state changes, and finally the amount of methane emitted (focusing on the ebullition pathway) in Lake Soyang, which is the largest reservoir in South Korea. Total organic carbon (TOC) concentrations were higher during summer after two years of heavy rainfall. The sedimentation rates of particulate organic carbon (POC) and particulate organic nitrogen (PON) were higher in the epilimnion and hypolimnion than the metalimnioin, indicating that autochthonous and allochthonous carbon made separate contributions to the TOC. During stratification, oxygen depletion occurred in the hypolimnion due to the decomposition of organic matter. Under these conditions, $H_2S$ and $CH_4$ can be released from sediment. The methane emissions from the reservoir were much higher than from other natural lakes. However, the temporal and spatial variations of methane ebullition were huge, and were clearly dependent on many factors. Therefore, more research via a well-organized field campaign is needed to investigate methane emissions.

A Bibliometric Analysis of Citation Patterns in Conference Papers of Information Science (학술대회 논문의 참고자료 인용패턴 분석 - 정보과학 분야를 중심으로 -)

  • Lee, Danielle
    • Journal of the Korean Society for Library and Information Science
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    • v.51 no.4
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    • pp.35-52
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    • 2017
  • This paper aims to explore the citation patterns of conference papers in 'Information Science' discipline and to analze impacts of various cited works-related factors on future citations of conference papers. Existing bibliometric studies has investigated citation patterns and the statistical relations between a variety of bibliographic factors and the future citations of literature. However, the attentions have been focused largely on journal articles, and the bibliometric studies targeting conference papers are still in an infant stage. Therefore, this study, which is based on 1,904 conference papers in 'Information Science' field, examined several citation patterns and the contributions of the factors about cited works - the number of cited works, type of cited works, citation rates and ages of cited works at the time of being cited and the rate of self-citedness - to the future citation of the citing target articles. The data source of this study including the properties of target articles and cited works and citation rates of target articles was Scopus. As the results, 53% and 29% of the cited works were conference papers and journal articles, respectively. 14% of them are non-traditional types such as web pages, technical reports, patent, etc. More than 60% of the cited works were 5 years old or less. Among several factors considered in this paper, the number of conference papers and the number of non-traditional types of works are the most contributing factors on the citation rates of target articles. The recency of the cited works is also significant contributor on the citation rates of target articles. That is, the target articles citing more conference papers and non-traditonal types of works earned more citations. The target articles citing recent works also earned more citations.

Estimation of Nutrients Intakes and Dietary Fiber Intake of Teenagers in Urban, Fishing, and Rural Areas. (일부 농어촌과 도시 청소년들의 영양소와 식이섬유 섭취실태)

  • 김말분;이연경;이혜성
    • Korean Journal of Community Nutrition
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    • v.2 no.3
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    • pp.281-293
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    • 1997
  • Dietary fiber(DF) intake of teenagers was estimated and the major food sources of fiber were analyzed using three-day food records and data from 365 middle school students in urban, rural and fishing areas. Mean dwily DF intake of males was 9.2$\pm$3.9g in urban, 10.4$\pm$5.4g in rural, and 7.9$\pm$4.0g in fishing areas and the intake of female was 10.6$\pm$5.1g in urban, 10.6$\pm$5.2g in rural, and 7.7$\pm$3.3g in fishing areas. When related to energy intake, female consumed more DF(5.7$\pm$2.5g/1000㎉, 7.0$\pm$3.5g/1000㎉, 4.6$\pm$2.2g/1000㎉, in urban, and rural, fishing areas respectively) than males(4.2$\pm$1.3g/1000㎉, 4.6$\pm$1.5g/1000㎉, 4.4$\pm$2.0g/1000㎉ in urban, rural, fishing respectively). Mean crude fiber(CF) intake of males was 4.1$\pm$1.7g, 4.5$\pm$2.4g, 3.7$\pm$2.4g, and female's intake was 4.7$\pm$1.9g, 4.8$\pm$2.2g, 3.7$\pm$1.9g in urban, rural, and fishing areas respectively. The mean DF : CF ratio for the subjects was 2.2-2.6, indicating that the DF intake is 2-3 times that of CF intakes. The intakes of the two measures of fiber were highly correlated(r=0.7781) . The major food sources for DF were cereals, vegetables and fruits and the percentage contributions of the food groups to the DF intake were 27-37$\%$, 22-30$\%$, and 11.5-19.7$\%$ respectively. The present study indicates that the DF intake of teenagers is considerably lower than the recommended level and they need to consume more DF than that indicated by the present levels. The importance of nutrition education on health and dietary pattern should also be emphasized among teenagers.

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Pollution Characteristics of Rainwater at Jeju Island during 2009~2010 (2009~2010년 제주지역 강우의 오염 특성 연구)

  • Kim, Ki-Ju;Bu, Jun-Oh;Kim, Won-Hyung;Lee, Yoon-Sang;Hyeon, Dong-Rim;Kang, Chang-Hee
    • Journal of Korean Society for Atmospheric Environment
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    • v.29 no.6
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    • pp.818-829
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    • 2013
  • The collection of rainwater samples was made at Jeju area during 2009~2010, and the major ionic species were analyzed. In the comparison of ion balance, conductivity, and acid fraction for the validation of analytical data, the correlation coefficients showed a good linear relationship within the range of 0.966~0.990. The volume-weighted mean pH and electric conductivity were 4.9 and $17.8{\mu}S/cm$, respectively, at the Jeju area. The volume-weighted mean concentrations of ionic species in rainwater were in the order of $Cl^-$ > $Na^+$ > $nss-SO_4{^{2-}}$ > $NH_4{^+}$ > $NO_3{^-}$ > $Mg^{2+}$ > $H^+$ > $nss-Ca^{2+}$ > $HCOO^-$ > $K^+$ > $PO_4{^{3-}}$ > $CH_3COO^-$ > $NO_2{^-}$ > $F^-$ > $HCO_3{^-}$ > $CH_3SO_3{^-}$. The ionic strength of rainwater was $0.26{\pm}0.21$ mM during the study period. The composition ratios of ionic species were such as 50.1% for the marine sources ($Na^+$, $Mg^{2+}$, $Cl^-$), 30.9% for the anthropogenic sources ($NH_4{^+}$, $nss-SO_4{^{2-}}$, $NO_3{^-}$), and 4.7% for the soil source ($nss-Ca^{2+}$), and 3.1% for organic acids ($HCOO^-$, $CH_3COO^-$). From the seasonal comparison, the concentrations of $NO_3{^-}$, $nss-Ca^{2+}$, and $nss-SO_4{^{2-}}$ increased in winter and spring seasons, indicating a reasonable possibility of long range transport from Asia continent. Especially, the acidifying contributions by major inorganic acids ($nss-SO_4{^{2-}}$ and $NO_3{^-}$) and organic acids ($HCOO^-$ and $CH_3COO^-$) were 87.6% and 12.4%, respectively. In comparison by sectional inflow pathway of air mass during the rainy sampling days, the concentrations of $nss-SO_4{^{2-}}$ and $NO_3{^-}$ were relatively high when the air mass was moved from the China continent into Jeju area.

The Controlling factors of Ra Isotopes in Masan Bay (마산만에서 Ra 동위원소의 농도를 결정하는 인자)

  • Kim Young Ill;Chung Chang Soo;Kim Suk Hyun;Moon Duk Soo;Park Jun Kun;Seo Sung Mo;Choi Jun Sun;Yang Dong Beom;Hong Gi Hoon
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.4 no.2
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    • pp.25-34
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    • 2001
  • /sup 226/Ra and /sup 228/Ra analysis were carried out at the representative station of Masan Bay from May to August, 1999. The high activities of /sup 226/Ra and /sup 228/Ra in the surface water were appeared in rainy season (August, 1). However, there is no significant variation in concentrations in the other season. A high negative linear correlation between /sup 226/Ra activities and salinity in the surface water suggests that /sup 226/Ra activity in the surface water was controlled by simple mixing between the two end-members low salinity high /sup 226/Ra activity water of inner Bay and a high salinity low /sup 226/Ra activity water of the continental shelf water out of Bay. /sup 226/Ra activities below the surface mixed layer were higher than those of expected level from the /sup 226/Ra versus salinity. And also /sup 228/Ra//sup 226/Ra ratios in the bottom water were lower compared to those in surface water due to the presence of potential source of /sup 226/Ra below the surface mixed layer. However, it is known that /sup 228/Ra compared to /sup 226/Ra is enriched in bottom sediments and pure water. Therefore, the most probable sources for low /sup 228/Ra//sup 226/Ra activity ration is submarine ground water discharge. Further studies are required to quantify the various sources of /sup 226/Ra and /sup 228/Ra and their relative contributions.

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